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Clinical trials for Leg

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    472 result(s) found for: Leg. Displaying page 1 of 24.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2008-004964-38 Sponsor Protocol Number: Trauma-fenta version 1 Start Date*: 2008-12-29
    Sponsor Name:Kari Leino
    Full Title: Perioperative pain treatment with fentanyl patch in trauma patients having an ankle or crural fracture/ Nilkka- ja säärimurtumapotilaiden perioperatiivinen kivunhoito fentanyylilaastarilla
    Medical condition: Patients having an ankle or crural fracture will be included.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061599 Lower limb fracture LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-004143-36 Sponsor Protocol Number: CL2-42909-016 Start Date*: 2017-05-30
    Sponsor Name:Ilkos Thérapeutique Inc.
    Full Title: Dose-response relationship study of S42909 on leg ulcer healing after oral repeated administration in patients with active venous leg ulcer. A 10-week randomized, double-blind, placebo-controlled...
    Medical condition: Venous leg ulcer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10068310 Leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DK (Prematurely Ended) CZ (Completed) SK (Completed) ES (Completed) PL (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-003252-30 Sponsor Protocol Number: Aston2008/1 Start Date*: 2009-03-20
    Sponsor Name:Aston University
    Full Title: Will the application of Morphine Gel to my leg ulcer ease the pain?
    Medical condition: Painful venous leg ulcers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066677 Chronic leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-000314-29 Sponsor Protocol Number: HULP2016-001 Start Date*: 2017-05-31
    Sponsor Name:Servicio de Angiología y cirugía vascular. Hospital Universitario La Paz
    Full Title: RANDOMIZED STUDY TO CHECK THE EFFECTIVENESS OF TOPICAL TREATMENT WITH PLATELET- RICH PLASMA IN THE HEALING OF LOWER LIMBS' VENOUS CHRONIC ULCERS
    Medical condition: Venous ulcers in lower limbs
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004858 10045373 Ulcers of extremities LLT
    20.0 100000004858 10024946 Lower extremities ulcers of LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003574-66 Sponsor Protocol Number: 34964 Start Date*: 2013-01-04
    Sponsor Name:Ortopædkirurgisk Forskning - Aarhus Universitetshospita
    Full Title: Osseointegrated transdermal femoral amputation prostheses - Denusomab Trial
    Medical condition: leg amputee
    Disease: Version SOC Term Classification Code Term Level
    16.0 10042613 - Surgical and medical procedures 10024124 Leg amputation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005667-26 Sponsor Protocol Number: 130256 Start Date*: 2007-07-11
    Sponsor Name:Ninewells Hospital
    Full Title: A randomised, placebo controlled trial of levobupivacaine or the combination of levobupivacaine and clonidine when administered as a sciatic perineural infusion for the prevention of phantom limb p...
    Medical condition: Pain after amputation
    Disease: Version SOC Term Classification Code Term Level
    8.1 10004227 Below knee amputation LLT
    9.1 10000243 Above knee amputation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-000875-33 Sponsor Protocol Number: PLATA Start Date*: 2013-08-27
    Sponsor Name:Academic Medical Center, University of Amsterdam
    Full Title: Prevention of Phantom Limb Pain After Transtibial Amputation (PLATA) - Randomized, double-blind, controlled, multi-center trial comparing Optimized intravenous pain control vs Optimized intravenous...
    Medical condition: Phantom limb pain following amputation of the lower leg due to critical limb ischemia.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10004227 Below knee amputation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) ES (Ongoing) AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-023426-20 Sponsor Protocol Number: AUGUST-2 Start Date*: 2011-04-08
    Sponsor Name:GWT-TUD GmbH
    Full Title: Low dose Urokinase therapy in patients with diabetic foot syndrome, critical limb ischemia as well as rest ischemia or missing of option revascularisation in comparison to the standard therapy - ra...
    Medical condition: Diabetic foot syndrome with critical limb ischemia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-005079-90 Sponsor Protocol Number: PPA/904W/003 Start Date*: 2008-12-18
    Sponsor Name:Photopharmica Ltd
    Full Title: Phase II randomised, placebo controlled trial to investigate repeat dose antimicrobial photodynamic therapy in patients with chronic leg ulcers
    Medical condition: Chronic leg ulcers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066677 Chronic leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-003402-25 Sponsor Protocol Number: OCT-UKE-2011 Start Date*: 2011-12-13
    Sponsor Name:Schülke & Mayr GmbH
    Full Title: Randomized, Double-blind, Single-center, Placebo-controlled Study to evaluate the Efficacy of octenisept® in Patients with Chronic Wounds.
    Medical condition: Chronic leg ulcers
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004858 10068310 Leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-019887-35 Sponsor Protocol Number: ABH-DERMAGRAFT-001-09 Start Date*: 2010-09-06
    Sponsor Name:Advanced BioHealing Inc
    Full Title: A Prospective, Multi-center, Longitudinal Cohort Study of Dermagraft® in Subjects with Venous Leg Ulcers: A Long-term Follow-up to the DEVO-Trial
    Medical condition: Venous leg ulcers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024134 Leg ulcer (exc varicose) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) EE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-005532-18 Sponsor Protocol Number: PLX-CLI-03 Start Date*: 2017-01-02
    Sponsor Name:Pluristem Ltd.
    Full Title: A Randomized, Double-Blind, Multicenter, Placebo-Controlled, Parallel-Group Phase III Study to Evaluate the Efficacy, Tolerability and Safety of Intramuscular Injections of PLX-PAD for the Treatmen...
    Medical condition: Critical Limb Ischemia (CLI)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004866 10058069 Critical limb ischemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) CZ (Prematurely Ended) AT (Completed) HU (Prematurely Ended) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-000381-36 Sponsor Protocol Number: 26083 Start Date*: 2006-04-26
    Sponsor Name:University of Nottingham
    Full Title: Randomised controlled trials to investigate whether prophylactic antibiotics can prevent further episodes of cellulitis (erysipelas) of the leg (PATCH I & PATCH II)
    Medical condition: Cellulitis of the leg
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001855-37 Sponsor Protocol Number: OCT02-2006 Start Date*: 2007-05-14
    Sponsor Name:Schülke & Mayr GmbH
    Full Title: Effect of an octenidine-based topical antimicrobial agent (Octenisept) on wound healing of chronic venous leg ulcers: a prospective, twelve-week comparison versus local treatment with Ringer soluti...
    Medical condition: Chronic venous leg ulcers In Germany, approximately three million people suffer from chronic leg ulcers of various origins. These ulcers are often very painful and extremely cost-intensive disease...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066677 Chronic leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) FR (Completed) HU (Prematurely Ended) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-010062-33 Sponsor Protocol Number: ABH-DERMAGRAFT-001-08 Start Date*: 2009-09-24
    Sponsor Name:Advanced BioHealing Inc
    Full Title: A Prospective, Multi-center, Randomized, Controlled Clinical Investigation of Dermagraft® in Subjects with Venous Leg Ulcers
    Medical condition: Venous leg ulcers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024134 Leg ulcer (exc varicose) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) GB (Completed) EE (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-003748-43 Sponsor Protocol Number: TKA 4 Start Date*: 2006-11-23
    Sponsor Name:Ortopædkirurgisk Center, Aarhus Universitets Hospital
    Full Title: Kan topical bisfosfonat øge fiksation og overlevelse af ucementeret knæledsprotese? Et prospektivt randomiseret migrations- og knogledensitetsstudie på tibia-implantater af trabeculært metal.
    Medical condition: Osteoarthritis of the knee treated with knee alloplastic
    Disease: Version SOC Term Classification Code Term Level
    8.1 10031200 Osteoarthrosis, localized, primary, involving lower leg LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-000235-14 Sponsor Protocol Number: allo-APZ2-PAOD-II-01 Start Date*: 2017-08-21
    Sponsor Name:RHEACELL GmbH & Co. KG
    Full Title: A RANDOMISED, PLACEBO-CONTROLLED, DOUBLE-BLIND, INTERVENTIONAL, MULTICENTER, PHASE I/IIA CLINICAL TRIAL TO INVESTIGATE THE EFFICACY AND SAFETY OF ALLO-APZ2-PAOD FOR THE TREATMENT OF PERIPHERAL ARTE...
    Medical condition: peripheral arterial occlusive disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 10047065 - Vascular disorders 10062585 Peripheral arterial occlusive disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) CZ (Prematurely Ended) AT (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005093-40 Sponsor Protocol Number: CS I-040202/01 Start Date*: 2007-10-22
    Sponsor Name:Kuros Biosurgery AG
    Full Title: A phase II randomized, controlled, open-labeled (dose-blinded) dose finding study of the safety and efficacy of I-040202 in the treatment of patients with acute open tibial shaft fractures
    Medical condition: Acute open tibial shaft fractures
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024956 Lower limb fractures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) FR (Completed) HU (Completed) SI (Completed) FI (Completed) CZ (Completed) SK (Completed) IT (Completed) BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003286-18 Sponsor Protocol Number: 802-247-09-032 Start Date*: 2013-11-06
    Sponsor Name:Smith & Nephew Inc.
    Full Title: A Phase 3 Randomized Safety and Efficacy Trial of HP802-247 in the Treatment of Chronic Venous Leg Ulcers (EU)
    Medical condition: Chronic venous leg ulcer
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004858 10066677 Chronic leg ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) PL (Prematurely Ended) DE (Prematurely Ended) BE (Completed) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2023-000170-97 Sponsor Protocol Number: 2023-01-1200-01 Start Date*: 2023-06-30
    Sponsor Name:LMU Universitätsklinikum München
    Full Title: A single dose of apixaban for the prevention of thrombotic events in the context of long-distance flights
    Medical condition: Symptomatic leg vein thrombosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 10047065 - Vascular disorders 10051055 Deep vein thrombosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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