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Clinical trials for Medical ethics

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    469 result(s) found for: Medical ethics. Displaying page 1 of 24.
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    EudraCT Number: 2010-021518-45 Sponsor Protocol Number: ARA290_PAIN_v1 Start Date*: 2010-07-12
    Sponsor Name:Leiden University Medical Center
    Full Title: A pilot study on the effect of ARA290 on pain and pain responses and retinal edema in patients with diabetes mellitus and neuropathic pain
    Medical condition: Neuropathic pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10054095 Neuropathic pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001487-23 Sponsor Protocol Number: TPU-SL-EU05-02 Start Date*: 2006-06-05
    Sponsor Name:Teikoku Pharma USA, Inc.
    Full Title: A Double Blind Randomized Controlled Study of the Effiacy and Safety of Topical Sterile 5% Lidocaine Patch in the Treatment of Postoperative Pain Due to Plastic Surgery of the Breast
    Medical condition: Postoperative Pain Due to the Plastic Surgery of the Breast
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: LV (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-000510-37 Sponsor Protocol Number: GTN-1 290107 Start Date*: 2008-04-25
    Sponsor Name:Nottingham Univeristy Hospitals NHS Trust
    Full Title: The effect of transdermal GTN on arterial size and procedure outcomes in transradial coronary angiography - pilot study.
    Medical condition: The trial is to investigate whether applying a transdermal GTN patch over the radial artery reduces spasm of the artery during coronary angiography. This is a pilot study
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001070-27 Sponsor Protocol Number: EP-PAE Metalyse Start Date*: 2005-07-07
    Sponsor Name:Division of Angiology Graz
    Full Title: Open, randomised, monosite pilot trial for comparison of thrombolytic efficacy of tenecteplase and alteplase in patients with acute pulmonary embolism
    Medical condition: Patients with acute pulmonary embolism and indication for thrombolytic therapy are included in the study
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-003563-22 Sponsor Protocol Number: CAT-1004-302 Start Date*: 2020-04-23
    Sponsor Name:Catabasis Pharmaceuticals Inc.
    Full Title: An Open-Label Extension Study of Edasalonexent in Pediatric Patients with Duchenne Muscular Dystrophy
    Medical condition: Duchenne Muscular Dystrophy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10013801 Duchenne muscular dystrophy PT
    Population Age: Children, Adolescents, Under 18 Gender: Male
    Trial protocol: GB (Prematurely Ended) IE (Prematurely Ended) DE (Prematurely Ended) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-001016-30 Sponsor Protocol Number: NODAGA-RGD-2 Start Date*: 2018-12-11
    Sponsor Name:Department of Nuclear Medicine, Medical University Innsbruck
    Full Title: PROSPECTIVE STUDY OF 68GA-NODAGA-RGD-PET FOR THE NON-INVASIVE DETERMINAITON OF THE INTEGRIN αvβ3 EXPRESSION IN PATIENTS WITH UNTREATED OR RECURRENT BREAST CANCER, COLORECTAL CANCER, NON-SMALL CELL ...
    Medical condition: Patient with untreated or reccurent breast cancer, non-small cell lung cancer, colorectal cancer and neuroendocrine tumors
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-002874-75 Sponsor Protocol Number: ov1005 Start Date*: 2007-09-10
    Sponsor Name:OVATION PHARMACEUTICALS INC
    Full Title: Safety and effectivness of Open- Label Melperone in the treatment of Patients with Psycosis Associated with Parkinson's Disease''
    Medical condition: Psycosis associated to Parkinson's Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027361 Mental disorders due to a general medical condition NEC HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-001093-55 Sponsor Protocol Number: NL77315.078.21 Start Date*: 2022-10-03
    Sponsor Name:Erasmus Medical center
    Full Title: COATS study: genetic Clopidogrel response testing to finetune the antithrombotic regimen in (D)OAC Treated patients undergoing PCI
    Medical condition: Patients on oral anticoagulation drugs who undergo a percutaneous coronary intervention (PCI) temporarily and treatment with concomitant antiplatelet therapy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002954-25 Sponsor Protocol Number: ASND0036 Start Date*: 2023-03-21
    Sponsor Name:Ascendis Pharma Growth Disorders A/S
    Full Title: ApproaCH: A Phase 2b, Multicenter, Double-Blind, Randomized, Placebo-controlled Trial evaluating Efficacy and Safety of Subcutaneous Doses of TransCon CNP Administered Once Weekly for 52 Weeks in C...
    Medical condition: Achondroplasia (ACH) in prepubertal children
    Disease: Version SOC Term Classification Code Term Level
    25.0 10010331 - Congenital, familial and genetic disorders 10000452 Achondroplasia LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: IE (Trial now transitioned) DK (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000464-29 Sponsor Protocol Number: CAT-1004-301 Start Date*: 2019-01-31
    Sponsor Name:Catabasis Pharmaceuticals, Inc.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, GLOBAL PHASE 3 STUDY OF EDASALONEXENT IN PEDIATRIC PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY
    Medical condition: Duchenne muscular dystrophy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10013801 Duchenne muscular dystrophy PT
    Population Age: Children, Under 18 Gender: Male
    Trial protocol: DE (Completed) SE (Completed) IE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005246-38 Sponsor Protocol Number: 143660 Start Date*: 2013-05-13
    Sponsor Name:University of Oslo
    Full Title: The effects of methylphenidate on brain processes for decision making in adult attention deficit hyperactivity disorder
    Medical condition: Attention deficit hyperactivty disorder
    Disease: Version SOC Term Classification Code Term Level
    15.1 10037175 - Psychiatric disorders 10003736 Attention deficit/hyperactivity disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002518-11 Sponsor Protocol Number: 8835-004 Start Date*: 2014-01-16
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL-GROUP STUDY TO ASSESS CARDIOVASCULAR OUTCOMES FOLLOWING TREATMENT WITH ERTUGLIFLOZIN (MK-8835/PF-04971729) IN SUBJECTS WITH TYPE 2 DIABETES ME...
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) NL (Completed) GB (Completed) IT (Completed) ES (Completed) BG (Completed) PL (Completed) GR (Completed) HR (Completed) SK (Completed) LT (Completed) LV (Completed) CZ (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-005695-14 Sponsor Protocol Number: 3165A1-1108-EU Start Date*: 2008-01-18
    Sponsor Name:Wyeth Research Division of Wyeth Pharmaceuticals Inc., Clinical Research and Development
    Full Title: A Double-Blind, Placebo-Controlled, Randomized, Single-Dose, 2-Period Crossover Study of the Pharmacodynamics of Orally Administered PSI-697 in Healthy Subjects Who Smoke
    Medical condition: PSI-697 is an orally active inhibitor of the cellular adhesion molecule P-selectin that offers a unique, first in class mechanism for preventing the vascular atherothrombotic state that is driven b...
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022809-18 Sponsor Protocol Number: 2010-022809-18 Start Date*: 2010-11-26
    Sponsor Name:Hywel Dda Health Board
    Full Title: Effectiveness of Glucophage® SR as an adjunct to insulin in improving glycaemic control, without increasing the episodes of hypoglycaemia, in non-overweight patients with type-1 Diabetes.
    Medical condition: Type-1 Diabetes Mellitus
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-004442-11 Sponsor Protocol Number: JAZ-01 Start Date*: 2020-12-01
    Sponsor Name:Zealand University Hospital
    Full Title: The effect of Melatonin in patients with Low Anterior Resection Syndrome
    Medical condition: Low anterior resection syndrome
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10080023 Low anterior resection syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-003885-19 Sponsor Protocol Number: NOT-APPLICABLE-HUFA Start Date*: 2023-03-15
    Sponsor Name:NO-COMERCIAL
    Full Title: ECOGUIDED GENICULAR NERVE BLOCK IN PATIENTS WITH KNEE OSTEOARTHRITIS BY LOCAL ANESTHETIC OR BY COMBINATION OF LOCAL ANESTHETIC AND CORTICOID: PLACEBO-CONTROLLED RANDOMIZED BLIND CLINICAL TRIAL
    Medical condition: KNEE OSTEOARTHRITIS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003688-24 Sponsor Protocol Number: P12.??? Start Date*: 2012-12-12
    Sponsor Name:Leiden University Medical Center
    Full Title: Treatment of Complex Regional Pain Syndrome type 1: A randomized placebo controlled double-blind study with ARA 290
    Medical condition: Complex regional pain syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001252-21 Sponsor Protocol Number: CSPP100A2230 Start Date*: 2005-06-30
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open-label, multiple-dose study to evaluate the pharmacokinetics, safety and tolerability of SPP100 (Aliskiren) and Atenolol (Tenormin®) administered alone and in combination in healthy subjects
    Medical condition: Hypertension
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004275-11 Sponsor Protocol Number: CASM981M2308 Start Date*: 2005-03-25
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An open-label study to investigate blood concentrations, safety, tolerability and efficacy of Elidel® Cream 1% in patients with moderate or severe seborrheic dermatitis treated topically for 3 weeks.
    Medical condition: Seborrheic dermatitis
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-003972-12 Sponsor Protocol Number: CAEB071A2201 Start Date*: 2005-01-25
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 2 week multiple ascending dose, double-blind placebo controlled study to evaluate the safety, tolerability and pharmacokinetics (PK) of twice daily administration of oral AEB071 and to explore th...
    Medical condition: moderate to severe chronic plaque psoriasis patients
    Disease: Version SOC Term Classification Code Term Level
    M15 10050576 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed) GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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