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Clinical trials for Metered dose inhalers

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    15 result(s) found for: Metered dose inhalers. Displaying page 1 of 1.
    EudraCT Number: 2005-005305-32 Sponsor Protocol Number: NEO-005 Start Date*: 2005-12-12
    Sponsor Name:Neolab Limited
    Full Title: A PHASE II, RANDOMISED, DOUBLE-BLIND, DOUBLE-DUMMY CROSSOVER STUDY TO DETERMINE THE SUPERIORITY OF HFA-PROPELLED COMBINATION FLUTICASONE PROPIONATE 125 mcg AND SALMETEROL XINAFOATE 25 mcg PRESSURIS...
    Medical condition: Mild to moderate asthma.
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-001724-20 Sponsor Protocol Number: D5899C00748 Start Date*: 2004-10-08
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, placebo-controlled, double-blind, double-dummy, crossover study to assess the onset of action of two inhalations of Symbicort 160/4.5μg compared with two inhalations of Seretide 25/2...
    Medical condition: This is an application for a phase III study to be conducted in COPD patients.
    Disease: Version SOC Term Classification Code Term Level
    10010952
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2021-001449-11 Sponsor Protocol Number: CLI-01535AA0-02 Start Date*: 2021-11-09
    Sponsor Name:CHIESI FARMACEUTICI S.P.A.
    Full Title: An exploratory, double-blind, randomised, multicenter, psychopharmacological study in adult patients with moderate to severe asthma to compare two pressurised Metered-Dose Inhalers (pMDIs) on patie...
    Medical condition: Moderate to severe asthma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-000512-25 Sponsor Protocol Number: MC/PR/033011/004/05 Start Date*: 2006-04-20
    Sponsor Name:CHIESI
    Full Title: DOUBLE BLIND, DOUBLE DUMMY, RANDOMISED, PARALLEL GROUP, MONOCENTRIC CLINICAL TRIAL ON THE EFFECTS OF CHF 1535 MDI OR SERETIDE DPI ON BIOLOGICAL AND FUNCTIONAL MARKERS OF SMALL AIRWAYS IN PATIENTS W...
    Medical condition: ASTHMA
    Disease: Version SOC Term Classification Code Term Level
    6.1 10003553 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-006078-84 Sponsor Protocol Number: BS558 Start Date*: 2008-07-24
    Sponsor Name:Generics [UK] Ltd trading as Merck Generics
    Full Title: A two-way crossover, sequential-dose, double-blinded, double-dummy, multiple dose, pharmacodynamic, comparative study of fluticasone propionate, 500 μg and 1000 μg twice daily delivered via pressu...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004905-11 Sponsor Protocol Number: D5890C00002 Start Date*: 2005-06-21
    Sponsor Name:AstraZeneca AB
    Full Title: Efficacy and safety of Symbicort® Turbuhaler® 160/4.5 µg/inhalation, two inhalations twice daily plus as-needed compared with Seretide™ Diskus™ 50/500 µg/inhalation, one inhalation twice daily plus...
    Medical condition: This is a Phase IIIB study to be performed in adult and adolescent asthmatic patients.
    Disease: Version SOC Term Classification Code Term Level
    10003553
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-002705-38 Sponsor Protocol Number: 3103013 Start Date*: 2014-11-18
    Sponsor Name:Orion Corporation Orion Pharma
    Full Title: STUDY COMPARING BRONCHODILATOR EFFICACY OF TWO DRY POWDER INHALERS, BUDESONIDE/FORMOTEROL EASYHALER AND SYMBICORT TURBUHALER; A RANDOMISED, DOUBLE-BLIND, DOUBLE-DUMMY, MULTICENTRE, SINGLE DOSE, CRO...
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    17.0 10038738 - Respiratory, thoracic and mediastinal disorders 10006070 Br. asthma LLT
    17.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-003588-31 Sponsor Protocol Number: CCD-1106-PR-0066 Start Date*: 2012-02-03
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A multicentre, randomised, double-blind, active-controlled, 4-way cross-over study to evaluate the efficacy and safety of a free combination of 3 doses of Glycopyrrolate with fixed combination Becl...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) HU (Completed) IT (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2013-004632-30 Sponsor Protocol Number: BDB-AS-302 Start Date*: 2015-05-16
    Sponsor Name:Teva Branded Pharmaceutical Products R&D, Inc.
    Full Title: A Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Parallel-Group, 12-Week Clinical Study to Assess the Efficacy and Safety of 80 or 160 mcg/Day of Beclomethasone Dipropionate Delivered ...
    Medical condition: Persistent Asthma
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: PL (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2013-002652-32 Sponsor Protocol Number: 1237.7 Start Date*: 2013-12-10
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: A randomised, placebo-controlled, double-blind, single dose, cross-over study to evaluate the efficacy and safety of orally inhaled tiotropium + olodaterol as both a fixed dose combination and a fr...
    Medical condition: Chronic Obstructive Pulmonary Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004855 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000135-26 Sponsor Protocol Number: 2006-04-DOS-2 Start Date*: 2007-06-08
    Sponsor Name:Hexal AG
    Full Title: Double-blind, double-dummy, multi-center, randomized parallel group trial to demonstrate therapeutic equivalence of Salmeterol/Fluticasone MDI HEXAL (25 µg/50 µg per actuation) versus SeretideTM 50...
    Medical condition: Persistent, moderate asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003555 Asthma bronchial LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: View results
    EudraCT Number: 2007-005235-29 Sponsor Protocol Number: 2007-41-DOS-3 Start Date*: 2008-03-28
    Sponsor Name:HEXAL AG
    Full Title: Efficacy and safety of Salmeterol/Fluticasone MDI HEXAL versus SeretideTM EvohalerTM in adolescent and adult patients with moderate-to-severe persistent asthma: A 12-week, multicenter, randomized, ...
    Medical condition: moderate-to-severe persistent asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003555 Asthma bronchial LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: HU (Completed) CZ (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2007-000134-39 Sponsor Protocol Number: 2006-03-DOS-1 Start Date*: 2007-04-19
    Sponsor Name:Hexal AG
    Full Title: Double-blind, double-dummy, multi-center, randomized parallel group trial to demonstrate therapeutic equivalence of Salmeterol/Fluticasone MDI HEXAL (25 µg/125 µg per actuation) versus SeretideTM 1...
    Medical condition: persistent moderate asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003555 Asthma bronchial LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: LT (Completed) HU (Completed) PL (Ongoing)
    Trial results: View results
    EudraCT Number: 2020-002389-16 Sponsor Protocol Number: CLI-05993AA3-06 Start Date*: 2021-01-06
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A phase III, 52-week, multinational, multicenter, randomized, double-blind, 2-arm parallel group study comparing efficacy, safety and tolerability of the fixed dose triple combination of beclometha...
    Medical condition: Chronic obstructive pulmonary disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004855 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned) HU (Trial now transitioned) BG (Trial now transitioned) PL (Trial now transitioned) RO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004429-26 Sponsor Protocol Number: CMP0119 Start Date*: 2020-05-08
    Sponsor Name:PRZEDSIEBIORSTWO FARMACEUTYCZNE LEK-AM SPÓŁKA Z OGRANICZONA ODPOWIEDZIALNOSCIA
    Full Title: A multicentre, randomized, open-label, cross-over equivalence study to compare the pharmacodynamic properties, safety, and tolerability of a new combination dry powder of fluticasone propionate and...
    Medical condition: asthma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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