interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development
EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).
The EU Clinical Trials Register currently displays
44336
clinical trials with a EudraCT protocol, of which
7366
are clinical trials conducted with subjects less than 18 years old.
The register also displays information on
18700
older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).
Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see
Frequently Asked Questions ).
Full Title: An open label, multicenter, single arm study of pasireotide LAR in patients with rare tumors of neuroendocrine origin
Medical condition: The following tumors are included:
1. NETs of the pancreas or duodenum: Insulinoma, Gastrinoma, VIPoma, glucagonoma,
2. Pituitary NETs: Thyrotropic-pituitary adenoma (TSH), Gonadotropic adenoma, Pr...
Full Title: An open label, multicenter, pilot phase II study of SOM230 s.c. in patients with duodeno-pancreatic (neuro) endocrine tumors and different pituitary diseases (Nelsonメs syndrome, non-functioning ad...
Medical condition: duodeno-pancreatic (neuro) endocrine tumors and different pituitary diseases (Nelsonメs syndrome, non-functioning adenoma, TSH-adenoma,Gonadotroph adenoma, and PRL-adenoma)
Full Title: Development of an innovative Gallium 68 radiolabeling of DOTATOC (68Ga-DOTATOC) for PET-CT imaging of neuro-endocrine tumors and preliminary clinical evaluation
Medical condition: neuroendocrine tumors
Disease:
Version
SOC Term
Classification Code
Term
Level
16.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: PHASE 1/2A DOSE ESCALATION, FINDING AND EXPANSION STUDY EVALUATING SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS AND ANTI TUMOR ACTIVITY OF PF-07104091 AS A SINGLE AGENT AND IN COMBINATI...
Medical condition: HR+ HER2- Metastatic Breast Cancer, Ovarian Cancer, Small Cell Lung Cancer (Part 1 also had Triple Negative BC and Non Small Cell Lung Cancer)
Disease:
Version
SOC Term
Classification Code
Term
Level
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10072737
Advanced breast cancer
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10033128
Ovarian cancer
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: PHASE 1B/2, OPEN-LABEL, MULTICENTER, DOSE ESCALATION AND DOSE EXPANSION STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTITUMOR ACTIVITY OF PF-07220060 IN COMB...
Medical condition: HR-positive HER2-negative metastatic/advanced BC
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10006187
Breast cancer
PT
20.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10055113
Breast cancer metastatic
PT
Population Age: Adults, Elderly
Gender: Male, Female
Trial protocol:BG(Trial now transitioned)CZ(Trial now transitioned)ES(Ongoing)
Trial results:(No results available)
EudraCT Number: 2021-002452-37
Sponsor Protocol Number: IMG-7289-CTP-202
Start Date*: 2022-01-27
Sponsor Name:Imago BioSciences Inc.
Full Title: A Multi-Center, Open Label, Extension Study Evaluating the Safety and Efficacy of Bomedemstat for the Treatment of Patients with Myeloproliferative Neoplasms (MPNs) Enrolled in a Prior Bomedemstat ...
Medical condition: Patients with Myeloproliferative Neoplasms (MPNs)
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: A Phase 2 Basket Study of Tucatinib in Combination with Trastuzumab in Subjects with Previously Treated, Locally Advanced Unresectable or Metastatic Solid Tumors Driven by HER2 Alterations
Medical condition: Previously Treated, Locally-Advanced Unresectable or Metastatic Solid Tumors Driven by HER2 Alterations
Disease:
Version
SOC Term
Classification Code
Term
Level
27.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10008593
Cholangiocarcinoma
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10017614
Gallbladder cancer
PT
27.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10025697
Malignant neoplasm of ampulla of Vater
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10064467
Urothelial carcinoma
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10006187
Breast cancer
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10008342
Cervix carcinoma
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10046766
Uterine cancer
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061873
Non-small cell lung cancer
PT
Population Age: Adults, Elderly
Gender: Male, Female
Trial protocol:BE(Trial now transitioned)NL(Ongoing)DE(Trial now transitioned)PL(Completed)IT(Completed)
Trial results:(No results available)
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• EEA CTAs: Date study was authorised to proceed • Outside EU/EEA: Date study was submitted in EudraCT