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Clinical trials for NRT

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    23 result(s) found for: NRT. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2007-006236-63 Sponsor Protocol Number: EVT 302/3011 Start Date*: 2008-01-23
    Sponsor Name:Evotec Neurosciences GmbH
    Full Title: A double-blind, randomized, placebo- and NRT-controlled Phase II study to assess the effects of EVT 302 alone and in combination with NRT on craving and withdrawal in healthy male smokers deprived ...
    Medical condition: Smoking cessation. Assessment of the effect of EVT 302 alone or in combination with a nicotine replacement therapy (NRT) on craving and withdrawal in smokers after short-term deprivation of cigare...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053325 Smoking cessation therapy LLT
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006426-34 Sponsor Protocol Number: 1705480563 Start Date*: 2009-03-06
    Sponsor Name:Pulmonary dept. Gentofte Hospital
    Full Title: Varenicline for long-term nicotine replacement therapy (NRT) users A double blind, placebo controlled trial
    Medical condition: Long-term dependence of nicotine substitution products (gum, inhaler, sublingual, spay)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005513-37 Sponsor Protocol Number: A3051148 Start Date*: 2012-07-25
    Sponsor Name:Pfizer Inc., 235 East 42nd Street, New York, NY 10017 US
    Full Title: A PHASE 4, NON-TREATMENT FOLLOW-UP FOR CARDIAC ASSESSMENTS FOLLOWING USE OF SMOKING CESSATION TREATMENTS IN SUBJECTS WITH AND WITHOUT A HISTORY OF PSYCHIATRIC DISORDERS
    Medical condition: Nicotine Addiction with the desire to quit smoking
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10053325 Smoking cessation therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) FI (Completed) BG (Completed) DK (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2005-000662-39 Sponsor Protocol Number: BMS2/05 Start Date*: 2005-10-04
    Sponsor Name:Oxford Brookes University
    Full Title: A 2x2 phase II randomized controlled trial to investigate the efficacy of NRT plus St John's wort versus NRT plus placebo in smoking cessation and to examine the efficacy of chromium nicotinate ve...
    Medical condition: Stopping smoking.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022334-92 Sponsor Protocol Number: qmul250510 Start Date*: 2011-01-07
    Sponsor Name:Barts and the London School of Medicine and Dentistry, Queen Mary University of London
    Full Title: Effects of a combination of varenicline and transdermal nicotine patch on post-quitting urges to smoke
    Medical condition: Tobacco dependence (smoking cessation)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001607-35 Sponsor Protocol Number: A3051044 Start Date*: 2005-01-26
    Sponsor Name:Pfizer Ltd.
    Full Title: AN OPEN-LABEL, MULTICENTER STUDY WITH FOLLOW-UP EVALUATING THE SAFETY AND EFFICACY OF VARENICLINE TARTRATE IN COMPARISON TO TRANSDERMAL NICOTINE PATCH FOR SMOKING CESSATION
    Medical condition: Partial nicotine agonist for use as an aid to smoking cessation.
    Disease: Version SOC Term Classification Code Term Level
    7.1 10057852 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017862-22 Sponsor Protocol Number: 200110005 Start Date*: 2010-09-28
    Sponsor Name:ZonMw
    Full Title: The effectiveness of Nicotine Replacement Therapy for young people aged 12 to 18 years
    Medical condition: Smoking among young people aged 12 – 18 years.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10053325 Smoking cessation therapy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005363-34 Sponsor Protocol Number: EC/2008/50/FAHS Start Date*: 2009-03-10
    Sponsor Name:University of Surrey
    Full Title: Investigation to explore whether there is a synergistic effect between nicotine replacement therapy and guided bodyscanning on cigarette cravings and withdrawal symptoms in temporarily abstinent sm...
    Medical condition: Healthy volunteers who currently smoke 10 or more cigarettes per day, for the last 3 years. The trial intends to explore whether there is a synergistic effect between the relaxation technique of g...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056484 Nicotine craving LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022914-15 Sponsor Protocol Number: A3051123 Start Date*: 2012-03-01
    Sponsor Name:Pfizer, S.L.U.
    Full Title: A PHASE 4, RANDOMIZED, DOUBLE-BLIND, ACTIVE AND PLACEBO -CONTROLLED, MULTICENTER STUDY EVALUATING THE NEUROPSYCHIATRIC SAFETY AND EFFICACY OF 12 WEEKS VARENICLINE TARTRATE 1MG BID AND BUPROPION HYD...
    Medical condition: Nicotine Addiction with the desire to quit smoking
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10053325 Smoking cessation therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) DE (Completed) DK (Completed) FI (Completed) BG (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2006-004461-34 Sponsor Protocol Number: 1.0 Start Date*: 2006-11-02
    Sponsor Name:University of Nottingham
    Full Title: Open label randomised trial of nicotine replacement therapy and oral smokeless tobacco (snus) in smoking cessation
    Medical condition: Smoking cessation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10053325 Smoking cessation therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-001237-65 Sponsor Protocol Number: Start Date*: 2017-06-29
    Sponsor Name:Queen Mary University of London, Joint Research Management Office
    Full Title: Helping Pregnant smokers quit: A multi-centre RCT of electronic cigarettes and nicotine patches
    Medical condition: Tobacco dependence/smoking cessation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10057852 Nicotine dependence PT
    20.0 100000004869 10008374 Cessation of smoking LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2008-006433-28 Sponsor Protocol Number: RG_08_082_a02 Start Date*: 2009-01-20
    Sponsor Name:University of Birmingham
    Full Title: Rapid reduction versus abrupt quitting for smokers who want to stop soon: a randomised controlled non-inferiority trial.
    Medical condition: Smoking and nicotine addiction.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056478 Nicotine addiction LLT
    9.1 10056484 Nicotine craving LLT
    9.1 10057852 Nicotine dependence LLT
    9.1 10008374 Cessation of smoking LLT
    9.1 10053325 Smoking cessation therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005134-19 Sponsor Protocol Number: RG_11-171 Start Date*: 2012-01-31
    Sponsor Name:University of Birmingham
    Full Title: An open label pragmatic randomised controlled trial of nicotine patch preloading for smoking cessation.
    Medical condition: The IMP will assist smoking cessation in smokers wishing to stop.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-006845-13 Sponsor Protocol Number: A6431111 Start Date*: 2009-02-02
    Sponsor Name:McNeil AB (Johnson & Johnson Consumer and Personal Products Worldwide, J&J CPPW)
    Full Title: Efficacy and safety following use of a novel nicotine replacement therapy. A multicenter, randomized, double blind, placebo-controlled, parallel group, 52-week study in smokers motivated to quit.
    Medical condition: For the treatment of tobacco dependence by relieving nicotine craving and withdrawal symptoms, thereby facilitating smoking cessation in smokers motivated to quit abruptly.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008374 Cessation of smoking LLT
    9.1 10053325 Smoking cessation therapy LLT
    9.1 10059612 Tobacco withdrawal symptoms LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-000106-24 Sponsor Protocol Number: RAA2006/004 Start Date*: 2006-06-26
    Sponsor Name:Kings College London (IOP)
    Full Title: Using genotype to tailor prescribing of nicotine replacement therapy: a randomised controlled trial assessing impact upon adherence
    Medical condition: Smoking addiction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022335-11 Sponsor Protocol Number: qmul010610 Start Date*: 2011-01-07
    Sponsor Name:Barts and the London School of Medicine and Dentistry, Queen Mary University of London
    Full Title: Effects of a tailored dose of varenicline on post-quitting urges to smoke
    Medical condition: Tobacco dependence (smoking cessation)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002621-46 Sponsor Protocol Number: 20878 Start Date*: 2005-06-27
    Sponsor Name:University of Nottingham
    Full Title: Double-blind, randomised, placebo-controlled trial of nicotine replacement therapy in pregnancy
    Medical condition: Smoking during pregnancy Specifically smoking 5 or more cigarettes currently (i.e. whilst pregnant) and having smoked 10 or more cigarettes prior to pregnancy.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-000922-22 Sponsor Protocol Number: TA-NIC/03 Start Date*: 2006-04-18
    Sponsor Name:Xenova Ltd
    Full Title: A phase II double blind, randomised, placebo controlled, multicentre study to assess the efficacy and safety of TA-NIC in maintaining smoking cessation when given in conjunction with Nicotine Repla...
    Medical condition: Prevention of relapse in smokers who have quit.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-023268-42 Sponsor Protocol Number: NICTDP2012 Start Date*: 2011-03-25
    Sponsor Name:McNeil AB
    Full Title: NICOTINE PHARMACODYNAMICS WITH A NEW ORAL NICOTINE REPLACEMENT PRODUCT AND NICOTINE GUM 4 MG. A STUDY IN HEALTHY SMOKERS.
    Medical condition: Tobacco Dependence
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-002472-99 Sponsor Protocol Number: EVT302/3009 Start Date*: 2008-08-12
    Sponsor Name:Evotec Neurosciences GmbH
    Full Title: A phase II multicenter, randomised, double-blind, parallel group, placebo-controlled, study to evaluate the effectiveness of EVT 302 in smoking cessation, effect on its own and in combination with ...
    Medical condition: Male or female subjects who are chronic smokers, but motivated to quit smoking will be recruited.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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