Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Nausea

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43886   clinical trials with a EudraCT protocol, of which   7296   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    810 result(s) found for: Nausea. Displaying page 1 of 41.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2015-003956-32 Sponsor Protocol Number: POSTPAL Start Date*: 2016-03-15
    Sponsor Name:Umeå University
    Full Title: Effects of postoperative palonosetron in ambulatory patients identified with high risk for postdischarge nausea and vomiting (PDNV) – a randomized controlled trial with comparison to placebo.
    Medical condition: Nausea and vomiting in the home (after discharge) after day-case surgery under general anesthesia-
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004856 10028817 Nausea and vomiting symptoms HLT
    18.1 100000004863 10036285 Postoperative nausea LLT
    18.1 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    18.1 100000004865 10054182 Perioperative nausea and vomiting prophylaxis LLT
    18.1 100000004863 10028818 Nausea postoperative LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003070-33 Sponsor Protocol Number: DANSAC-RCT Start Date*: 2015-11-30
    Sponsor Name:Odense University Hospital
    Full Title: DANSAC-RCT: Fosaprepitant in patients with advanced cancer not receiving chemotherapy or irradiation; A multicenter, randomized, double-blind, placebo-controlled study.
    Medical condition: Emesis
    Disease: Version SOC Term Classification Code Term Level
    18.1 10017947 - Gastrointestinal disorders 10028817 Nausea and vomiting symptoms HLT
    18.1 10017947 - Gastrointestinal disorders 10014542 Emesis LLT
    18.1 10017947 - Gastrointestinal disorders 10028813 Nausea PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000351-33 Sponsor Protocol Number: 2005/2:5 Start Date*: 2007-07-26
    Sponsor Name:Karolinska Universitetssjukhuset Solna
    Full Title: Will paracetamol reduce the opioid requirements and the (opioid)related postoperative nausea?
    Medical condition: Paracetamol is used as a complimentary painrelief. Using sealed envelopes, 140 patients will be randomly assigned to receive either 1g paracetamol as tablets (Panodil® Glaxo Smith Kline) or 1g plac...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028818 Nausea postoperative LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003189-33 Sponsor Protocol Number: NHLPal Start Date*: 2006-10-31
    Sponsor Name:G.I.S.L. - GRUPPO ITALIANO STUDIO LINFOMI
    Full Title: Phase II study with Palonosetron alone in preventing chemotherapy-induced nausea and vomiting in untreated patients with aggressive Non Hodgkin’s Lymphomas who underwent moderately emetogenic chemo...
    Medical condition: preventing chemotherapy-induced nausea and vomiting in untreated patients with aggressive Non Hodgkin’s Lymphomas who underwent moderately emetogenic chemotherapy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028817 Nausea and vomiting symptoms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-000658-39 Sponsor Protocol Number: AkupresSNP Start Date*: 2016-07-11
    Sponsor Name:Region Jönköpings län
    Full Title: Randomized multicenter study of Acupressure combined with personalized antiemetics based on genetic variations (SNPs) in women undergoing neoadjuvant or adjuvant chemotherapy EC / FEC against breas...
    Medical condition: Nausea in conjuction with neoadjuvant or adjuvant chemotherapy (FEC/EC) for patients with breast cancer.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005216-28 Sponsor Protocol Number: VNK115640 Start Date*: 2012-04-05
    Sponsor Name:GlaxoSmithKline
    Full Title: A Multicenter, Randomized, Single-blind, Active-controlled, Parallel Group, Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of a Single Intravenous (6 mg, 12 mg, 18 mg, 24 mg or 3...
    Medical condition: Post-operative nausea and vomiting (PONV)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10036285 Postoperative nausea LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) GB (Prematurely Ended) PL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001339-37 Sponsor Protocol Number: 2008-001339-37 Start Date*: 2008-04-10
    Sponsor Name:AZIENDA OSPEDALIERA S. MARIA DI TERNI
    Full Title: Aprepitant in the prevention of cisplatin-induced delayed emesis: a double-blind randomized study
    Medical condition: patiens with different cancers submitted to single dose of cisplatin chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017947 SOC
    9.1 10028817 HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001237-95 Sponsor Protocol Number: 2008-001237-95 Start Date*: 2008-04-10
    Sponsor Name:AZIENDA OSPEDALIERA S. MARIA DI TERNI
    Full Title: Aprepitant in the prevention of delayed emesis induced by moderately emetogenic chemotherapy (cyclophosphamide + anthracycline) in breast cancer patients: a double-blind randomized study
    Medical condition: patients with breast cancer receiving chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017947 SOC
    9.1 10028817 HLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004853-27 Sponsor Protocol Number: Palonosetron Start Date*: 2007-09-05
    Sponsor Name:OSPEDALE POLICLINICO S. MATTEO
    Full Title: A phase IV monocentre study to evaluate palonosetron in nausea/vomiting prevention in patients with breast or colon cancer, treated with moderately aemotogenic chemotherapic agents
    Medical condition: nausea and vomiting prevention
    Disease: Version SOC Term Classification Code Term Level
    9.1 10054133 Prophylaxis of nausea and vomiting LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2016-003260-39 Sponsor Protocol Number: ML16633 Start Date*: 2016-08-05
    Sponsor Name:F. Hoffmann-La Roche AG
    Full Title: Intravenous Granisetron (Kytril) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy
    Medical condition: Prevention of Post-operative Nausea and Vomiting (PONV) in pediatric subjects
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2009-013543-11 Sponsor Protocol Number: 2009057 Start Date*: 2009-10-19
    Sponsor Name:James Cook University Hospital
    Full Title: A comparison of nausea with two routine ways of managing low blood pressure after delivery of the baby during spinal anaesthesia for Caesarean section.
    Medical condition: We are investigating nausea associated with hypotension caused by spinal anaesthesia in healthy women undergoing elective Caesarean section. NICE recommend phenylephrine in this population. The aim...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002428-34 Sponsor Protocol Number: ANE-DEX-2019 Start Date*: 2019-09-27
    Sponsor Name:HOSPITAL CLINICO SAN CARLOS
    Full Title: ONE CENTRE, DOUBLE BLIND, ONE CENTRE, RANDOMIZED CLINICAL TRIAL, IN TWO PARALLEL GROUPS TO EVALUATE THE EFICACY IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING OF DEXAMETHASONE VERSUS METHIL...
    Medical condition: Postoperative nausea and vomiting after not urgent laparoscopic cholecystectomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005928-13 Sponsor Protocol Number: 52/2005 Start Date*: Information not available in EudraCT
    Sponsor Name:Landspitali-University Hospital
    Full Title: Prospective randomized double blind trial on the use of Scopoderm patch for control of post-operative nausea and vomitting in patients undergoing gynecologic laparoscopic procedures.
    Medical condition: Post-operative nausea and vomiting in patients undergoing gynecologic laparoscopic procedures.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: IS (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-003730-20 Sponsor Protocol Number: NEPA-15-31 Start Date*: 2020-09-17
    Sponsor Name:Helsinn Healthcare SA
    Full Title: A multicenter, multinational, randomized, double-blind, pharmacokinetic and pharmacodynamic (PK/PD) dose-finding study of oral netupitant administered concomitantly with oral palonosetron in pediat...
    Medical condition: nausea and vomiting associating with emetogenic chemotherapy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10047700 Vomiting PT
    20.0 10017947 - Gastrointestinal disorders 10028813 Nausea PT
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2015-003992-30 Sponsor Protocol Number: DP10019 Start Date*: 2016-03-08
    Sponsor Name:Acacia Pharma Ltd
    Full Title: Randomised, double-blind, placebo-controlled study of APD421 (amisulpride for IV injection) as treatment of established post-operative nausea and vomiting, in patients who have had prior prophylaxis
    Medical condition: Post-operative nausea and vomiting
    Disease: Version SOC Term Classification Code Term Level
    19.0 10022117 - Injury, poisoning and procedural complications 10066962 Procedural nausea PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-013923-43 Sponsor Protocol Number: Nichel-SNAS/09 Start Date*: 2010-03-03
    Sponsor Name:LOFARMA
    Full Title: Studio in doppio cieco controllato con placebo sulla efficacia e tollerabilita' della terapia desensibilizzante con nichel in pazienti affetti da sindrome sistemica da allergia al nichel
    Medical condition: Pazienti affetti da SNAS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10046736 HLT
    9.1 10017926 HLT
    9.1 10013949 HLT
    9.1 10028817 HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022746-24 Sponsor Protocol Number: TS-P04834 Start Date*: 2012-05-07
    Sponsor Name:Tesaro, Inc.
    Full Title: A Phase 3, Multicenter, Randomized, Double-Blind, Active-Controlled Study of the Safety and Efficacy of Rolapitant for the Prevention of Chemotherapy- Induced Nausea and Vomiting (CINV) in Subject...
    Medical condition: Chemotherapy-Induced Nausea and Vomiting (CINV) in Subjects Receiving Moderately Emetogenic Chemotherapy (MEC)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10049091 Chemotherapy antiemetic prophylaxis LLT
    14.1 10042613 - Surgical and medical procedures 10054133 Prophylaxis of nausea and vomiting PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) LV (Completed) ES (Completed) BE (Completed) CZ (Completed) PL (Completed) BG (Completed) SK (Completed) PT (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022971-79 Sponsor Protocol Number: PALO-10-14 Start Date*: 2011-05-23
    Sponsor Name:Helsinn Healthcare SA
    Full Title: A Multicenter, Double-blind, Double-dummy, Randomized, Parallel Group, Stratified Study to Evaluate the Efficacy and Safety of a Single IV Dose of Palonosetron Compared to a Single IV Dose of Ondan...
    Medical condition: Postoperative nausea and vomiting (PONV)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10022117 - Injury, poisoning and procedural complications 10036238 Postoperative vomiting LLT
    14.0 10022117 - Injury, poisoning and procedural complications 10036285 Postoperative nausea LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed) HU (Completed)
    Trial results: View results
    EudraCT Number: 2015-002041-59 Sponsor Protocol Number: DP10018 Start Date*: 2015-09-11
    Sponsor Name:Acacia Pharma Ltd
    Full Title: Randomised, double-blind, placebo-controlled study of APD421 (amisulpride for IV injection) as treatment of established post-operative nausea and vomiting, in patients who have had no prior prophyl...
    Medical condition: Post-operative nausea and vomiting
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022117 - Injury, poisoning and procedural complications 10066962 Procedural nausea PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004789-20 Sponsor Protocol Number: GDW07/08 Start Date*: 2008-09-05
    Sponsor Name:UZLEUVEN
    Full Title: ” A comparative double-blind placebo-controlled study between alizapride and ondansetron for the prevention of postoperative nausea and vomiting.”
    Medical condition: Prevention of post-operative nausea and vomiting.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: BE (Completed)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Tue May 21 23:14:48 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA