interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development
EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
Clinical Trials Information System (CTIS).
The EU Clinical Trials Register currently displays
44336
clinical trials with a EudraCT protocol, of which
7366
are clinical trials conducted with subjects less than 18 years old.
The register also displays information on
18700
older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).
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8 result(s) found for: Neuroepithelial cells.
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EudraCT Number: 2010-022221-15
Sponsor Protocol Number: PM104-B-003-10
Start Date*: Information not available in EudraCT
Sponsor Name:Pharma Mar S.A., Sociedad Unipersonal
Full Title: Phase II Multicenter, Open-label, Clinical and Pharmacokinetic Study of Zalypsis®
(PM00104) in Patients with Unresectable Locally Advanced and/or Metastatic Ewing
Family of Tumors (EFT) Progressing...
Medical condition: Advanced and/or Metastatic Ewing Family of Tumors (EFT)
Disease:
Version
SOC Term
Classification Code
Term
Level
12.1
10057846
Primitive neuroectodermal tumour
LLT
12.1
10015560
Ewing's sarcoma
LLT
12.1
10015759
Extra-osseous Ewing's sarcoma
LLT
12.1
10057656
Askin's tumour
LLT
Population Age: Adolescents, Under 18, Adults, Elderly
Full Title: Window-of-opportunity study of chemo-immunotherapy in patients with resectable Merkel Cell Carcinoma prior to surgery: the MERCURY trial
Medical condition: The disease under clinical investigation is represented by resectable Merkel Cell Carcinoma (MCC), stage IIA-III (according to the AJCC staging system 8th edition). The study will include patients ...
Full Title: Prospective randomized trial of an adjuvant therapy of completely resected Merkel Cell Carcinoma (MCC) with immune checkpoint blocking antibodies (Nivolumab, Opdivo®; Ipilimumab, Yervoy®) versus ob...
Medical condition: completely resected Merkel cell carcinoma
Disease:
Version
SOC Term
Classification Code
Term
Level
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Sponsor Name:Bristol-Myers Squibb International Corporation
Full Title: Non-Comparative, Open-Label, Multiple Cohort, Phase 1/2 Study of Nivolumab and Nivolumab plus Ipilimumab in Subjects with Virus-Positive and Virus-Negative Solid Tumors
Medical condition: Virus-associated tumors
Disease:
Version
SOC Term
Classification Code
Term
Level
20.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10017758
Gastric cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10060121
Squamous cell carcinoma of head and neck
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10008229
Cervical cancer
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10046885
Vaginal cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061306
Nasopharyngeal cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10047777
Vulvar cancer
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10064025
Merkel cell carcinoma
LLT
Population Age: Adults, Elderly
Gender: Male, Female
Trial protocol:NL(Completed)DE(Completed)BE(Completed)GB(GB - no longer in EU/EEA)ES(Completed)
Sponsor Name:Incyte Biosciences International Sàrl
Full Title: A Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 in Combination With Immune Therapies in Subjects With Advanced or Metastatic Malignancies.
Medical condition: Phase 1: advanced or metastatic cervical cancer, endometrial cancer, gastric cancer, hepatocellular carcinoma, melanoma (mucosal or cutaneous), Merkel cell carcinoma, mesothelioma, MSI-H colorectal...
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10041067
Small cell lung cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10060121
Squamous cell carcinoma of head and neck
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10014733
Endometrial cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10027407
Mesothelioma malignant
PT
20.0
100000017553
10064467
Urothelial carcinoma
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10073071
Hepatocellular carcinoma
PT
20.0
100000018529
10027150
Melanoma malignant
LLT
20.0
100000018548
10064025
Merkel cell carcinoma
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10017758
Gastric cancer
PT
20.0
100000020977
10008229
Cervical cancer
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061873
Non-small cell lung cancer
PT
11.0
100000005104
10038408
Renal cell carcinomas
HLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10061451
Colorectal cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10075566
Triple negative breast cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Full Title: Randomized phase III trial of standard immunotherapy (IO) by checkpoint inhibitors, versus reduced dose intensity of IO in patients with metastatic cancer in response after 6 months of standard IO
Medical condition: Oncologic metastatic tumour (lung cancer (K), renal cell K (except IMDC favorable-risk treated TKI / immunotherapy [IO] combination), head and neck K, bladder K, triple negative breast K, Merkel K ...
Disease:
Version
SOC Term
Classification Code
Term
Level
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10025044
Lung cancer
LLT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10038407
Renal cell cancer
LLT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10067821
Head and neck cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10005003
Bladder cancer
PT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10075566
Triple negative breast cancer
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10053571
Melanoma
LLT
20.0
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
10073071
Hepatocellular carcinoma
PT
21.1
10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)
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