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Clinical trials for Obesity

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    423 result(s) found for: Obesity. Displaying page 1 of 22.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2011-006193-36 Sponsor Protocol Number: P091122 Start Date*: 2016-02-16
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title:
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004861 10027966 Morbid obesity LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-001361-16 Sponsor Protocol Number: PI-11-PR-REGIMBEAU-2 Start Date*: 2013-11-21
    Sponsor Name:CHU AMIENS
    Full Title: Randomized prospective clinical study evaluating the usefulness of fibrin glue (TISSEEL) to prevent gastric fistula, intra abdominal haemorrhage and intra abdominal loco regional collections after ...
    Medical condition: morbid obesity sleeve gastrectomy
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004861 10027966 Morbid obesity LLT
    16.1 10042613 - Surgical and medical procedures 10059610 Obesity surgery PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005287-94 Sponsor Protocol Number: Stulnig_PUFA1 Start Date*: 2008-05-06
    Sponsor Name:Medizinische Universität Wien
    Full Title: Impact of n-3 Polyunsaturated Fatty Acids on Adipose Tissue Inflammation in Morbidly Obese Patients
    Medical condition: morbid obesity
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027966 Morbid obesity LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-006082-88 Sponsor Protocol Number: Rimonamaag Start Date*: 2008-10-21
    Sponsor Name:UZLeuven
    Full Title: INFLUENCE OF RIMONABANT ON GASTRIC SENSITIVITY AND ON THE GASTRIC RESPONSE TO A MEAL IN HEALTHY VOLUNTEERS
    Medical condition: none; this is a physiological study to investigate the influence of CB1 receptor antagonism by rimonabant (normally used for the treatment of obesity) on gastric sensorimotor function
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029883 Obesity LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002755-42 Sponsor Protocol Number: 1069/12 Start Date*: 2012-11-06
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: OBESITY AND ASPIRIN RESPONSIVENESS
    Medical condition: OBESITY
    Disease: Version SOC Term Classification Code Term Level
    15.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002274-31 Sponsor Protocol Number: U1111-1215-8606 Start Date*: 2020-12-16
    Sponsor Name:Department of Biomedical Sciences, University of Copenhagen
    Full Title: Young adults with early-onset obesity treated with semaglutide
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029885 Obesity, unspecified LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-001716-71 Sponsor Protocol Number: RIMON_C_01346 Start Date*: 2006-09-12
    Sponsor Name:sanofi aventis Groupe
    Full Title: A RANDOMIZED, DOUBLE BLIND, TWO ARM, PARALLEL, PLACEBO CONTROLLED STUDY OF RIMONABANT 20MG EFFECT ON HIGH DENSITY LIPOPROTEIN KINETICS IN PATIENTS WITH ABDOMINAL OBESITY AND ADDITIONAL CARDIOMETABO...
    Medical condition: PATIENTS WITH ABDOMINAL OBESITY AND ADDITIONAL CARDIOMETABOLIC RISK FACTORS
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059179 Abdominal obesity LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed) GB (Prematurely Ended) FR (Completed)
    Trial results: View results
    EudraCT Number: 2006-004534-32 Sponsor Protocol Number: MK-0364 037 Start Date*: 2006-10-17
    Sponsor Name:Suomen MSD Oy
    Full Title: A Phase IIb/III Randomized, Placebo-controlled Clinical Trial to Study the Safety and Efficacy of MK-0364 in Obese Patients and in Overweight Patients with Obesity-related Co-morbidities.
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    8.1 10027966 Morbid obesity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended) SE (Prematurely Ended) DE (Completed) DK (Prematurely Ended) FR (Prematurely Ended) CZ (Completed) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001711-30 Sponsor Protocol Number: RIMON_R_00961 Start Date*: 2006-10-11
    Sponsor Name:sanofi aventis Groupe
    Full Title: A Pan-European randomized, parallel group, two-arm placebo-controlled, double-blind multicenter study of Rimonabant 20mg once daily in the treatment of abdominally obese patients with impaired fast...
    Medical condition: abdominally obese patients with impaired fasting blood glucose with or without other comorbidities
    Disease: Version SOC Term Classification Code Term Level
    8.1 10059179 Abdominal obesity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) BE (Completed) PT (Prematurely Ended) CZ (Completed) SI (Completed) FR (Completed) NL (Prematurely Ended) NO (Completed) FI (Prematurely Ended) SE (Prematurely Ended) DK (Prematurely Ended) LT (Prematurely Ended) HU (Completed) SK (Completed) GR (Completed) AT (Prematurely Ended) IT (Prematurely Ended) BG (Prematurely Ended) GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-004951-35 Sponsor Protocol Number: DISOBBED-12 Start Date*: 2013-01-18
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA DI CAGLIARI
    Full Title: Disulfiram, obesity and binge eating disorder
    Medical condition: Obesity and binge eating disorder
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022308-34 Sponsor Protocol Number: JW/IB/AG Start Date*: 2011-04-19
    Sponsor Name:Central Manchester Foundation Hospitals Trust
    Full Title: Eplerenone in Metabolic Syndrome: An investigation into the effects of Eplerenone on perivascular adipose tissue and small artery tone in obesity
    Medical condition: Obesity and Metabolic Syndrome (combination of obesity, hypertension, raised blood glucose and cholesterol abnormalities)
    Disease: Version SOC Term Classification Code Term Level
    13.1 10027433 - Metabolism and nutrition disorders 10052066 Metabolic syndrome PT
    13.1 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015982-29 Sponsor Protocol Number: UMCU-Vasc-14A Start Date*: 2010-07-27
    Sponsor Name:University Medical Center Utrecht
    Full Title: A randomized, placebo-controlled, double blind, 4-period, cross-over trial, to study the effects of aliskiren, hydrochlorothiazide and moxonidine on endothelial dysfunction in obesity related hyper...
    Medical condition: Hypertension in subjects with abdominal obesity and the metabolic syndrome
    Disease: Version SOC Term Classification Code Term Level
    12.1 10059179 Abdominal obesity LLT
    12.1 10052066 Metabolic syndrome LLT
    12.1 10020772 Hypertension LLT
    12.1 10065941 Central obesity LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-009278-29 Sponsor Protocol Number: S51477 Start Date*: Information not available in EudraCT
    Sponsor Name:UZ Leuven
    Full Title: Follow-up studie: Metformin therapie bij kinderen en adolescenten met neurogene of neuromusculaire aandoeningen
    Medical condition: Neuromuscular and neurological diseases, associated with obesity and insulin resistance
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022489 Insulin resistance LLT
    9.1 10022489 Insulin resistance PT
    9.1 10029883 Obesity LLT
    9.1 10065941 Central obesity PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-002077-31 Sponsor Protocol Number: RIMON_L_01814 Start Date*: 2008-09-09
    Sponsor Name:SANOFI-AVENTIS S.P.A
    Full Title: Effects of Rimonabant on urinary albumin excretion rate on the components of the metabolic syndrome in patients with type 2 diabetes mellitus and microalbuminuria on background ramipril treatment. ...
    Medical condition: Abdominal obese patients with type 2 diabetes mellitus and microalbuminuria.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059179 Abdominal obesity LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016417-15 Sponsor Protocol Number: 0908104 Start Date*: 2010-01-07
    Sponsor Name:CHU de SAINT-ETIENNE
    Full Title: Fondaparinux population pharmacokinetic to morbid obese patients in post-operatory bariatric surgery
    Medical condition: obese patients
    Disease: Version SOC Term Classification Code Term Level
    12.0 10027966 Morbid obesity LLT
    12.0 10059610 Obesity surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001384-27 Sponsor Protocol Number: 2022-031 Start Date*: 2023-02-28
    Sponsor Name:Franciscus Gasthuis & Vlietland
    Full Title: Peroperative Administration of Tranexamic acid in Roux-en-Y and one-anastomosis gastric bypass to reduce hemorrhage rates (PATRY study): a randomized controlled trial
    Medical condition: Morbid obesity
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10059610 Obesity surgery LLT
    21.0 100000004861 10027966 Morbid obesity LLT
    21.1 100000004865 10068900 Bariatric surgery LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-003473-34 Sponsor Protocol Number: NN9536-4376 Start Date*: 2018-05-03
    Sponsor Name:Novo Nordisk A/S
    Full Title: Effect and safety of semaglutide 2.4 mg once-weekly in subjects with overweight or obesity who have reached target dose during run-in period
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) NL (Completed) PT (Completed) DK (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-001840-38 Sponsor Protocol Number: BET207 Start Date*: 2008-08-05
    Sponsor Name:OBEcure
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Examine the Effect of Betahistine on Body Weight in Obese Female Subjects
    Medical condition: obesity
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029883 Obesity LLT
    Population Age: Adults Gender: Female
    Trial protocol: BE (Completed) NL (Completed) DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-002862-20 Sponsor Protocol Number: NS2330-001 Start Date*: 2006-08-03
    Sponsor Name:NeuroSearch A/S
    Full Title: Effect of tesofensine on weight reduction in patients with obesity. A randomised, double-blind, placebo-controlled, parallel-group, multi-centre study.
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    8.1 10029883 Obesity LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-000204-11 Sponsor Protocol Number: NN9536-4578 Start Date*: 2021-01-11
    Sponsor Name:Novo Nordisk A/S
    Full Title: Effect of subcutaneous semaglutide 2.4 mg once-weekly compared to placebo in subjects with obesity and knee osteoarthritis
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DK (Completed) SE (Completed) NO (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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