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Clinical trials for Occlusion effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44335   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    355 result(s) found for: Occlusion effect. Displaying page 1 of 18.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2012-000800-13 Sponsor Protocol Number: V1 Start Date*: 2013-01-24
    Sponsor Name:Universitätsklinik für Augenheilkunde und Optometrie
    Full Title: Influence of sustained-release dexamethasone on intraocular cytokines and growth factors and retinal blood vessels in retinal vein occlusion
    Medical condition: Retinal vein occlusion
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10066426 Hemiretinal vein occlusion LLT
    14.1 10015919 - Eye disorders 10007972 Central retinal vein occlusion LLT
    14.1 10015919 - Eye disorders 10038907 Retinal vein occlusion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2018-001842-33 Sponsor Protocol Number: CRTH258C2301 Start Date*: 2019-06-14
    Sponsor Name:Novartis Pharma AG
    Full Title: An Eighteen-Month, Two-Arm, Randomized, Double Masked, Multi center, Phase III Study Assessing the Efficacy and Safety of Brolucizumab versus Aflibercept in Adult Patients with Visual Impairment du...
    Medical condition: Branch retinal vein occlusion
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10038907 Retinal vein occlusion PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended) DK (Prematurely Ended) ES (Prematurely Ended) GB (GB - no longer in EU/EEA) IT (Prematurely Ended) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005450-71 Sponsor Protocol Number: LUZVT06 Start Date*: 2007-06-29
    Sponsor Name:Augenklinik der LMU München
    Full Title: INTRAVITREAL RANIBIZUMAB THERAPY FOR MACULA EDEMA SECONDARY TO CENTRAL RETINAL VEIN OCCLUSION (RAVO)
    Medical condition: Macula edema resulting from central retinal vein occlusion in the eye
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-001788-21 Sponsor Protocol Number: CRTH258C2302 Start Date*: 2019-06-06
    Sponsor Name:Novartis Pharma AG
    Full Title: An Eighteen-Month, Two-Arm, Randomized, Double Masked, Multi center, Phase III Study Assessing the Efficacy and Safety of Brolucizumab versus Aflibercept in Adult Patients with Visual Impairment du...
    Medical condition: Central retinal vein occlusion
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004853 10007972 Central retinal vein occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended) DE (Prematurely Ended) HU (Completed) NL (Prematurely Ended) GR (Prematurely Ended) FI (Completed) ES (Prematurely Ended) GB (GB - no longer in EU/EEA) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-002546-36 Sponsor Protocol Number: 2018-002546-36 Start Date*: 2020-03-10
    Sponsor Name:Oslo University Hospital
    Full Title: TENECTEPLASE IN CENTRAL RETINAL ARTERY OCCLUSION STUDY (TenCRAOS): A PROSPECTIVE, RANDOMIZED-CONTROLLED, DOUBLE-DUMMY, DOUBLE-BLIND PHASE 3 MULTI-CENTRE TRIAL OF TNK 0.25 MG/KG + PLACEBO VS. ASA...
    Medical condition: Central retinal artery occlusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned) LT (Completed) FI (Trial now transitioned) DK (Trial now transitioned) IE (Trial now transitioned) BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-005473-20 Sponsor Protocol Number: V121102015 Start Date*: 2016-11-23
    Sponsor Name:UZ Leuven
    Full Title: Pilot study on robot assisted retinal vein cannulation with ocriplasmin infusion for central retinal vein occlusion.
    Medical condition: Patients with central retinal vein occlusion (CRVO)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-002675-17 Sponsor Protocol Number: TIGER-BVS Start Date*: 2014-05-30
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Ticagrelor and absorb bioresorbable vascular scaffold implantation for recovery of vascular function after successful chronic total occlusion recanalization
    Medical condition: Chronic total coronary occlusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2018-002008-15 Sponsor Protocol Number: NL65095.041.18 Start Date*: 2018-06-08
    Sponsor Name:University Medical Center Utrecht
    Full Title: Optimal cerebral perfusion after an extracranial-intracranial bypass: should we increase blood pressure or cardiac output?
    Medical condition: Patients with an indication for an extracranial-intracanial bypass (e.g. Moya Moya Disease, occluded carotid artery, giant aneurysm)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10029999 Occlusion carotid LLT
    20.1 100000004852 10002333 Aneurysm cerebral LLT
    20.1 100000004852 10002337 Aneurysm intracranial LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-002086-54 Sponsor Protocol Number: NTR5685 Start Date*: 2018-09-03
    Sponsor Name:University Medical Center Utrecht
    Full Title: A randomized trial of the effect of antiplatelet therapy (Aspirin, Aspirin and Clopidogrel or Ticagrelor) on the occurrence of atherothrombotic and cardiovascular adverse events following lower ext...
    Medical condition: It is known that the atherothrombotic cardiovascular adverse event rate in patients with peripheral artery disease (PAD) is high. Also patency rates after (endo)vascular interventions in PAD patien...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002142-50 Sponsor Protocol Number: POPCABG03 Start Date*: 2019-04-09
    Sponsor Name:St. Antonius Hospital
    Full Title: A Randomized, Double-Blind, Placebo-Controlled Trial Investigating The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery.
    Medical condition: Coronary artery bypass grafting surgery with the use of one or more saphenous vein grafts.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000765-20 Sponsor Protocol Number: ANTIVEGFVEP Start Date*: 2015-11-27
    Sponsor Name:Kuopion yliopistollinen sairaala/silmätautien poliklinikka
    Full Title: The Effect of Intravitreal Bevacizumab Injections in Patients with Macular Oedema Caused by AMD, CRVO or DME on the Plasticity of Nerves Studied by Visual Evoked Potentials
    Medical condition: Wet age-related macular degeneration, diabetic macular edema, central retinal vein occlusion
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004853 10012675 Diabetic macular retinopathy LLT
    18.1 100000004853 10007972 Central retinal vein occlusion LLT
    18.1 100000004853 10015902 Exudative senile macular degeneration of retina LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002289-21 Sponsor Protocol Number: 48655 Start Date*: 2015-11-26
    Sponsor Name:Academic Medical Center
    Full Title: Parameters in fractional laser assisted delivery of topical anesthetics: role of laser type, laser settings, type of anesthetic and occlusion time
    Medical condition: local anesthesia of the skin prior to minor cutaneous surgical procedures
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-002329-27 Sponsor Protocol Number: ETLAS-2 Start Date*: 2020-12-10
    Sponsor Name:Herlev Gentofte Hospital
    Full Title: Improving cerebral blood flow and cognition in patient with cerebral small vessel disease. The ETLAS-2 Trial.
    Medical condition: Cerebral small vessel disease and stroke.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10029205 - Nervous system disorders 10070879 Cerebral small vessel ischemic disease LLT
    22.1 10029205 - Nervous system disorders 10076994 Lacunar stroke PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002089-37 Sponsor Protocol Number: CLS1003-302 Start Date*: 2018-09-27
    Sponsor Name:Clearside Biomedical, Inc.
    Full Title: TOPAZ: A RANDOMIZED, MASKED, CONTROLLED TRIAL TO STUDY THE SAFETY AND EFFICACY OF SUPRACHOROIDAL CLS-TA IN COMBINATION WITH AN INTRAVITREAL ANTI-VEGF AGENT IN SUBJECTS WITH RETINAL VEIN OCCLUSION
    Medical condition: Retinal Vein Occlusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) HU (Completed) EE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-000189-12 Sponsor Protocol Number: ABR43234 Start Date*: 2013-03-14
    Sponsor Name:University Medical Centre Nijmegen
    Full Title: Effects of the selective mineralocorticoid receptor antagonist eplerenone on extracellular formation of adenosine
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-005685-30 Sponsor Protocol Number: 2015-005685-30 Start Date*: 2016-04-08
    Sponsor Name:Hôpital Erasme
    Full Title: Evaluation of microcirculation alterations in cardiac surgery, by FMD (Flow Mediated vasoDilation), Near Infrared Spectrophotometry (NIRS) and biological analysis
    Medical condition: Cardiac pathology eligible for surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-000238-16 Sponsor Protocol Number: APD791-202 Start Date*: 2021-05-07
    Sponsor Name:Arena Pharmaceuticals, Inc.
    Full Title: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Effect on Microvascular Obstruction of Temanogrel in Subjects Undergoing Percutane...
    Medical condition: Microvascular Obstruction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004866 10079682 Microvascular occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended) SE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-002622-75 Sponsor Protocol Number: 2013 Start Date*: 2013-05-21
    Sponsor Name:Vibeke Hjortdal
    Full Title: Lymphatic dysfunction as a cause of calcium channel blocker oedema
    Medical condition: Fluid accumulation in the leg associated with calcium channel blocker therapy.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004867 10067033 Drug side effect LLT
    16.0 100000004867 10034570 Peripheral edema LLT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-004342-42 Sponsor Protocol Number: 201302 Start Date*: 2014-03-26
    Sponsor Name:Medisch Centrum Alkmaar
    Full Title: The effect of fish oil supplements on hemorheological parameters and walking distance in patients with intermittent claudication
    Medical condition: Patients suffering from intermittent claudication
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004866 10067825 Peripheral arterial disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-001466-21 Sponsor Protocol Number: 61364 Start Date*: 2017-10-19
    Sponsor Name:Erasmus MC University Medical Center
    Full Title: Multicenter Randomized CLinical trial of Endovascular treatment for Acute ischemic stroke in the Netherlands. The effect of periprocedural MEDication: heparin, antiplatelet agents, both or neither.
    Medical condition: Acute ischemic stroke
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000013700 10055221 Ischemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing) FR (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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