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Clinical trials for Orthopedics

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    10 result(s) found for: Orthopedics. Displaying page 1 of 1.
    EudraCT Number: 2006-006439-39 Sponsor Protocol Number: Packat ver 5 Start Date*: 2007-04-25
    Sponsor Name:Lund University Hospital
    Full Title: Bisfosfonatbehandling av bentransplantat vid höftrevisionhöftplastikrevision utvärderat med radiostereofotogrametri. En randomiserad, dubbel-blind studie hos patienter opererade för osteolys och as...
    Medical condition: Revision of hip prostheses with osteolysis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-001481-18 Sponsor Protocol Number: 6925 Start Date*: 2011-10-07
    Sponsor Name:Uppsala University Hospital
    Full Title: Uncemented total hip implant and subcutaneous injection of Denosumab for patients with osteoarthritis of the hip. A randomised double blind placebo controlled study on the effects on bone evaluated...
    Medical condition: Patients with osteoarthritis of the hip treated with an uncemented total hip arthroplasty. This procedure is accompanied with an increased risk for loss of bone adjacent to the implants
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2020-003444-80 Sponsor Protocol Number: 2020-01471 Start Date*: 2020-11-17
    Sponsor Name:Sahlgrenska University Hospital
    Full Title: Evaluation of the clinical implementation of biofilm susceptibility to antibiotics using Minimum Biofilm Eradication Concentration (MBEC) in addition to Minimum Inhibitory Concentration (MIC) to gu...
    Medical condition: Periprosthetic hip or knee joint infections
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-000870-36 Sponsor Protocol Number: 1447 Start Date*: 2015-03-26
    Sponsor Name:Maxima Medical center
    Full Title: Epiphysiodesis for adolescents; what is the most effective postoperative pain treatment? An RCT
    Medical condition: expected excessive body heigth
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004193-41 Sponsor Protocol Number: 35RC14_9179 Start Date*: 2014-12-12
    Sponsor Name:CHU de Rennes
    Full Title: Development of a tool for adapting dosage of fluoroquinolones by using a population pharmacokinetic model
    Medical condition: pharmacokinetics of fluoroquinolones
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002608-33 Sponsor Protocol Number: KI CLINTEC mikro 02 Start Date*: 2006-10-27
    Sponsor Name:Karolinska Institute, CLINTEC, div of orthopedics
    Full Title: En dubbelblind placebokontrollerad studie för utvärdering av postoperativa analgetikaeffekter via mikrodialys synovialt på patienter som genomgår artroskopi.
    Medical condition: Painfull knee condition of traumatic or other origin, where arthroscopic surgery is indicated, as judged by the surgeon.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-004393-28 Sponsor Protocol Number: 06-2011 Start Date*: 2012-07-12
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: "Effectiveness of leech therapy in treatment of chronic low back pain - a randomised controlled clinical study"
    Medical condition: chronic low back pain -diagnosis assured by specialist (orthopedy, neurology, pain therapy) as chronic low back pain for at least 3 month caused by nonspecific lumbar syndrome - averaged pain int...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-000242-17 Sponsor Protocol Number: Protocol_PPB_TKA_14012021 Start Date*: 2021-03-12
    Sponsor Name:Region Hospital Silkeborg
    Full Title: The effect of the popliteal plexus block on postoperative opioid consumption, pain, muscle strength and mobilization after total knee arthroplasty - a randomized, controlled, blinded study
    Medical condition: Postoperative pain following a total knee arthroplasty surgery
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2014-004474-42 Sponsor Protocol Number: V3_06082015 Start Date*: 2015-05-07
    Sponsor Name:Copenhagen University Hospital at Hvidovre
    Full Title: Treatment of equinus gait caused by dynamic tightening of the calf muscles in children with cerebral palsy. A randomized, placebo controlled Botulinum toxin type A volume/response study.
    Medical condition: Treatment of equinus gait caused by dynamic tightening of the calf muscles in children with cerebral palsy.
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004859 10015112 Equinus deformity of foot, acquired LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003003-22 Sponsor Protocol Number: N-20170060 Start Date*: 2017-11-27
    Sponsor Name:Aalborg University Hospital, Department of Orthopedics [...]
    1. Aalborg University Hospital, Department of Orthopedics
    2. Mogens Brouw Jørgensen
    Full Title: postoperative effect of optimal multimodal pain management supplemented with systemic single dose of Dexamethason in the first week after UKA. Low dose (8mg) or mean dose
    Medical condition: knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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