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Clinical trials for Osteoarthritis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43874   clinical trials with a EudraCT protocol, of which   7293   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    370 result(s) found for: Osteoarthritis. Displaying page 1 of 19.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2016-001906-41 Sponsor Protocol Number: MRHT_ES-IF_RCT001 Start Date*: 2016-08-08
    Sponsor Name:Royal College of Surgeons in Ireland
    Full Title: A randomised control trial of intra articular injectates in knee osteoarthritis: A comparison of corticosteroid (Methylprednisolone Acetate) and NSAID (Ketorolac tromethamine) injections
    Medical condition: Knee osteoarthritis is the condition of interest. Osteoarthritis is a common musculoskeletal complaint, with an underlying pathogenesis related to bio-mechanical stress loading, resulting in initia...
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001132-23 Sponsor Protocol Number: CCOX189A2369 Start Date*: 2004-07-01
    Sponsor Name:NOVARTIS FARMA
    Full Title: A 52-week, international, multicenter, randomized, double-blind, double-dummy, parallel-group clinical trial to compare retention on treatment, safety, tolerability and efficacy of lumiracoxib 100m...
    Medical condition: Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    6.1 10031164 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-004796-39 Sponsor Protocol Number: PT-SM-14-OA Start Date*: 2013-04-30
    Sponsor Name:Fondazione IRCCS Policlinico San Matteo
    Full Title: A Comparative Study of Oxycodone/Naloxone versus Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Knee and/or hip Pain Due to Osteoarthritis
    Medical condition: Moderate to Severe Chronic Knee and/or hip Pain Due to Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    14.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-001830-16 Sponsor Protocol Number: 42160443PAI3001 Start Date*: 2015-11-11
    Sponsor Name:Janssen-Cilag International NV
    Full Title: Randomized, 16-Week, Multi-Phase, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Fulranumab as Adjunctive Therapy in Subjects with Signs and Symptoms o...
    Medical condition: Osteoarthritis of the Hip or Knee
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004859 10023476 Knee osteoarthritis LLT
    18.1 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) HU (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2021-005020-38 Sponsor Protocol Number: KF7039-02 Start Date*: 2022-07-12
    Sponsor Name:Grünenthal GmbH
    Full Title: A randomized, double-blind, placebo-controlled, Phase III trial to evaluate the efficacy and safety of a single intra-articular injection of RTX-GRT7039 in adult subjects with pain associated with ...
    Medical condition: Moderate to severe pain associated with osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) DK (Ongoing) PT (Completed) BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2021-005046-15 Sponsor Protocol Number: KF7039-03 Start Date*: 2022-06-22
    Sponsor Name:Grünenthal GmbH
    Full Title: A single-arm, open-label, Phase III trial to evaluate the safety and tolerability of intra-articular injections of RTX-GRT7039 in subjects with moderate to severe pain associated with osteoarthrit...
    Medical condition: Moderate to severe pain associated with Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    21.1 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Ongoing) PL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004931-25 Sponsor Protocol Number: INDEX Start Date*: 2021-09-10
    Sponsor Name:Turku University Hospital
    Full Title: Intranasal dexmedetomidine pharmacokinetics on patients under general anesthesia
    Medical condition: Knee osteoarthritis Hip osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10020108 Hips osteoarthritis LLT
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000444-26 Sponsor Protocol Number: TM-CS+SG/301 Start Date*: 2013-05-24
    Sponsor Name:Tedec-Meiji Farma, S.A.
    Full Title: Phase III clinical trial to evaluate the efficacy and safety of chondroitin sulphate and glucosamine sulphate in combination versus placebo in patients with osteoarthritis of the knee.
    Medical condition: Knee osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-003205-18 Sponsor Protocol Number: Cingal17-02 Start Date*: 2018-01-26
    Sponsor Name:Anika Therapeutics, Inc.
    Full Title: Extension Study to Cingal 16-02: Trial Extension to 39 Week Follow Up in the Randomized, Double-Blind, Active Comparator Controlled, Multi-Center Study of a Single Injection Cross-Linked Sodium Hya...
    Medical condition: Osteoarthritis of the Knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001501-13 Sponsor Protocol Number: GS PSPK2 Start Date*: 2007-07-31
    Sponsor Name:ROTTAPHARM / ROTTA RESEARCH LABORATORIUM
    Full Title: An open, randomized study to investigate the plasma and synovial fluid concentrations of glucosamine before and after repeated doses of crystalline glucosamine sulfate administered as oral soluble ...
    Medical condition: Joint disorders
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048794 Gonarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-019684-11 Sponsor Protocol Number: 2010-WL01 Start Date*: 2010-06-09
    Sponsor Name:Maasstad Hospital
    Full Title: Pharmacological Treatment in Osteoarthritis
    Medical condition: Osteoarthritis of the hand
    Disease: Version SOC Term Classification Code Term Level
    12.1 10019115 Hand osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002675-97 Sponsor Protocol Number: ONO-4474-02 Start Date*: 2016-12-23
    Sponsor Name:Ono Pharmaceutical Co., Ltd.
    Full Title: A randomised, double-blind, placebo controlled, parallel group, multi-centre, study to evaluate the efficacy, safety, tolerability and pharmacokinetics of ONO-4474 in patients with pain due to oste...
    Medical condition: Osteoarthritic Pain
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004859 10073925 Generalised osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DK (Prematurely Ended) ES (Completed) PL (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-015849-22 Sponsor Protocol Number: 2009/147 Start Date*: 2010-01-27
    Sponsor Name:Salford Royal Foundation NHS Trust
    Full Title: An open label study of intra-articular steroid injection in the management of symptomatic knee OA
    Medical condition: Osteoarthritis of the Knee
    Disease: Version SOC Term Classification Code Term Level
    6.1 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-011785-28 Sponsor Protocol Number: CEN BIOTECH 150309 Start Date*: 2009-10-12
    Sponsor Name:SUBSTIPHARM DEVELOPPEMENT
    Full Title: Multicenter randomized, double blind, 3 parallel arms, controlled trial of the clinical efficacy of topical 'Diclofenac 1%, gel' (diclofenac diethylamine 1.16%) for the treatment of osteoarthritis ...
    Medical condition: Patient présentant une ostéorthrose douloureuse d'au moins un des genoux.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10031165 Osteoarthritis knee LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004114-28 Sponsor Protocol Number: 0801-38 Start Date*: 2009-04-01
    Sponsor Name:Erasmus Medical Center; Department of general practice [...]
    1. Erasmus Medical Center; Department of general practice
    2. Fonds NutsOhra
    Full Title: Effectiveness of Diclofenac versus Paracetamol in primary care patients with knee osteoarthritis.
    Medical condition: Knee Osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001185-20 Sponsor Protocol Number: 167700-005CL Start Date*: 2017-12-05
    Sponsor Name:Proximagen Limited
    Full Title: A Randomized, Double Dummy, Parallel Arm, Placebo and Active Controlled, Double Blind, Study of the Safety and Efficacy of PRX167700 as Monotherapy in Adults with Moderate to Severe Knee Pain Due ...
    Medical condition: Moderate to Severe Knee Pain Due to Osteoarthritis in subjects who are Inappropriate for Oral Non steroidal Anti inflammatory Therapy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031161 Osteoarthritis PT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10023476 Knee osteoarthritis LLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031165 Osteoarthritis knee LLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10024776 Localised osteoarthritis LLT
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10031166 Osteoarthritis knees LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-006485-42 Sponsor Protocol Number: 35GA0608 Start Date*: 2007-03-08
    Sponsor Name:Q-Med AB
    Full Title: Double-Blind, Randomized, Parallel Group, Multicenter Study of Durolane Compared to Methylprednisolone in Subjects with Osteoarthritis of the Knee
    Medical condition: Osteoarthritis of the knee
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004718-27 Sponsor Protocol Number: INRETRAM3/2014 Start Date*: 2017-01-11
    Sponsor Name:Medical Unviersity of Warsaw
    Full Title: A randomised, multicenter, single-blinded, parallel-group study to assess efficacy, safety and tolerability of the combination of Immediate Release (IR) tramadol with micronized magnesium lactate a...
    Medical condition: Chronic knee and/or hip pain due to Osteoarthritis.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-004441-32 Sponsor Protocol Number: MSV-crio Start Date*: 2013-03-06
    Sponsor Name:Fundación Teknon
    Full Title: Pilot clinical trial to determine the feasibility and safety of MSV * cryopreserved in the treatment of gonartrosis. * MSV = mesenchymal progenitor cells of expanded autologous bone marrow with GMP...
    Medical condition: Patients diagnosed with gonarthrosis II, III and IV degrees of Kellgren and Lawrence
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012956-26 Sponsor Protocol Number: 1690 Start Date*: 2009-06-08
    Sponsor Name:AZIENDA OSPEDALIERA ISTITUTI OSPITALIERI DI VERONA
    Full Title: Randomized clinical trial on efficacy and tolerability of intra-articular clodronate compared to placebo in knee osteoarthritis
    Medical condition: Knee osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048794 Gonarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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