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Clinical trials for Periodontal Treatment

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44359   clinical trials with a EudraCT protocol, of which   7383   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    31 result(s) found for: Periodontal Treatment. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2019-002239-27 Sponsor Protocol Number: RAM-LIG-2019-01 Start Date*: 2019-09-24
    Sponsor Name:Clinica Dental AndreuDental
    Full Title: Study on the relationship between periodontal disease and serum levels of ultrasensitive Reactive C-Protein and fibrinogen
    Medical condition: Patients with a diagnosis of periodontitis: There is interdental LCI in two or more non-adjacent teeth, or two or more teeth have a vestibular LCI ≥ 3 with a PD > 3 mm
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005883-25 Sponsor Protocol Number: Scil-MD05-C02 Start Date*: 2007-04-25
    Sponsor Name:Scil Technology GmbH
    Full Title: Pilot Study on Safety and Explorative Efficacy of MD05 in Comparison with Open Flap Debridement in Patients Undergoing Periodontal Surgery to Treat Deep Intrabony Defects
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    8.1 10034536 Periodontal disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001367-36 Sponsor Protocol Number: DoxP-01/2006 Start Date*: 2006-12-05
    Sponsor Name:Prof. Dr. Peter Eickholz
    Full Title: Benefit of adjunctive systemic postsurgical doxycycline in regenerative periodontal surgery
    Medical condition: Periodontitis is an opportunistic infectious disease that destroys the periodontal attachment and bone. Bacterial plaque (biofilm) on the teeth adjacent to the gingiva is the necessary cause gingiv...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10034539 Periodontitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-003940-21 Sponsor Protocol Number: 46361 Start Date*: 2014-03-20
    Sponsor Name:University Medical Center Groningen
    Full Title: Systemic antibiotic therapy (amoxicillin plus metronidazole) as an adjunct to surgical treatment of peri-implantitis; a single blind randomized controlled study
    Medical condition: peri-implantitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000741-39 Sponsor Protocol Number: 6996 Start Date*: 2019-11-07
    Sponsor Name:Hôpitaux Universitaires de Strasbourg
    Full Title: EFFECT OF AZITHROMYCIN ON THE PROPORTION OF FAILURES OF SEVERE PERIODONTITIS NON-SURGICAL TREATMENTS : A RANDOMIZED, DOUBLE-BLIND VERSUS PLACEBO STUDY
    Medical condition: Periodontology
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-002625-35 Sponsor Protocol Number: PERIOC_CTP001 Start Date*: 2015-01-26
    Sponsor Name:PerioC Ltd
    Full Title: The effect of locally delivered ciclosporin as an adjunct to healing after treatment of periodontal pockets
    Medical condition: Moderate to severe chronic periodontitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-005188-12 Sponsor Protocol Number: Clinical Protocol Start Date*: 2005-02-25
    Sponsor Name:University of Leeds
    Full Title: DENTAL TRAUMA: The effectiveness of an internet based computer database for data collection in a randomised controlled trail to evaluate immediate extirpation of necrotic pulp tissue and placement ...
    Medical condition: Tooth Avulsion and Replantation
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-004493-34 Sponsor Protocol Number: 2017/06NOV/503 Start Date*: 2018-01-02
    Sponsor Name:Cliniques universitaires Saint-Luc
    Full Title: Evaluation of multiple subgingival irrigations with 10% povidone iodine after scaling and root planing : a randomized clinical trial
    Medical condition: Periodontitis is characterized by alveolar bone loss induced by the host immune response to bacterial insult. Because povidone iodine is known to be a powerful antiseptic, there is biologic rationa...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001167-75 Sponsor Protocol Number: FIBEA-04-EC-19-ALV Start Date*: 2019-09-09
    Sponsor Name:BTI I MAS D
    Full Title: Randomized Clinical Trial, conventional treatment-controlled, studying the efficacy of Plasma Rich in Growth Factor (PRGF®) in alveolar ridge preservation after simple exodontia in the anterior reg...
    Medical condition: Alveolar ridge preservation after exodontia of uniradiculate dental pience in the anterior region of maxilla
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001068-39 Sponsor Protocol Number: ECPAF11/16 Start Date*: 2018-07-24
    Sponsor Name:OMEQUI
    Full Title: Changes in the bone morphology of the post-extraction socket, preserved with platelet-rich fibrin and leukocytes (L-PRF) versus Conventional treatment
    Medical condition: Regenerative potential of L-PRF
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004457-10 Sponsor Protocol Number: PS0104 Start Date*: 2006-01-16
    Sponsor Name:Laboratoires Expanscience
    Full Title: Clinical and biological activity of Piascledine® 300 in patients with chronic periodontitis
    Medical condition: CHRONIC PERIODONTITIS
    Disease: Version SOC Term Classification Code Term Level
    8.1 10009102 Chronic periodontitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004825-42 Sponsor Protocol Number: Notapplicablenow Start Date*: 2016-12-22
    Sponsor Name:ACTA
    Full Title: Effect of Delmopinol on treatment of Peri - implant mucositis : a randomised controlled clinical trial
    Medical condition: Peri implant mucositis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2006-005854-61 Sponsor Protocol Number: ABPARO Start Date*: 2008-02-15
    Sponsor Name:University Hospital Muenster
    Full Title: Adjunctive antimicrobial therapy of periodontitis: Long-term effects on disease progression and oral microbiological colonization
    Medical condition: periodontal disease (moderate to severe)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10034539 Periodontitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003541-15 Sponsor Protocol Number: 2019-Fungi Start Date*: 2020-02-19
    Sponsor Name:Aarhus University
    Full Title: Adjunct effect of fluconazole in the treatment of Candida-associated refractory severe periodontitis – A single-center, placebo-controlled, triple blind, randomized clinical trial
    Medical condition: Periodontitis. The participants are in good general health, but have at least 2 residual dental lesions after periodontal treatment (standard care).
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004862 10009102 Chronic periodontitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-005202-19 Sponsor Protocol Number: DyMZIS-01 Start Date*: 2017-09-07
    Sponsor Name:Chemische Fabrik Kreussler & Co. GmbH
    Full Title: Multicenter, randomized, split-mouth study to evaluate the acceptance and preference of lidocaine gel compared to injection anesthesia after non surgical periodontal treatment
    Medical condition: Moderate parodontitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002532-16 Sponsor Protocol Number: 02 Start Date*: 2017-12-05
    Sponsor Name:Cliniques Universitaires Saint-Luc
    Full Title: Adjunctive systemic antimicrobial therapy in the surgical treatment of peri-implantitis. A prospective randomized clinical study
    Medical condition: To treat patients with chronic infection of dental implants. One group with antibiotics and one group without.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-005062-61 Sponsor Protocol Number: Protocol01 Start Date*: 2017-03-30
    Sponsor Name:Cliniques universitaires Saint-Luc
    Full Title: Effects of vitamin D supplementation during a non-surgical treatment of generalized chronic periodontitis: a randomized double-blinded placebo-controlled clinical trial
    Medical condition: generalized chronic periodontitis
    Disease: Version SOC Term Classification Code Term Level
    19.1 100000004862 10009102 Chronic periodontitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000836-24 Sponsor Protocol Number: OP-P-5267 Start Date*: 2012-06-14
    Sponsor Name:OraPharma, Inc.
    Full Title: Multi-Center Phase 3 Trial of Minocycline HCl 1mg Microspheres for the Use in Subjects with Peri-Implantitis
    Medical condition: Peri-Implantitis, defined as a condition around an osseointegrated dental implant having at least one peri-implant site with probing depth (PD) ≥5 mm and ≤7 mm that exhibits bleeding on probing and...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004711-23 Sponsor Protocol Number: DT11/9936 Start Date*: 2013-05-22
    Sponsor Name:Leeds Dental Institute
    Full Title: Comparative studies of the anaesthetic efficacy of 4% Articaine used as mandibular infiltration versus 2% Lidocaine used as inferior dental nerve block, in extraction and pulpotomy of mandibular pr...
    Medical condition: Dental caries in primary molars
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006617-32 Sponsor Protocol Number: 06/Q0605/1 Start Date*: 2007-05-02
    Sponsor Name:Kings College Hospital Trust R&D
    Full Title: A prospective randomised double blind parallel trial comparing Articaine versus Lignocaine for mandibular dentistry
    Medical condition: necessary dental surgery
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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