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Clinical trials for Pharmacological effect

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    217 result(s) found for: Pharmacological effect. Displaying page 1 of 11.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2018-002637-37 Sponsor Protocol Number: NL66693.058.18 Start Date*: 2020-06-29
    Sponsor Name:Leiden University
    Full Title: Manipulating NMDA-dependent learning to alter nocebo effects: A pharmacological fMRI study on pain and itch.
    Medical condition: Nocebo effects on pain and itch
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004812-73 Sponsor Protocol Number: BP18-1-501 Start Date*: 2022-05-16
    Sponsor Name:Leiden University
    Full Title: The influence of pharmacological conditioning with S-ketamine on pain sensitivity in patients with Fibromyalgia Syndrome
    Medical condition: Fibromyalgia Syndrome
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2008-001384-11 Sponsor Protocol Number: captaf Start Date*: 2008-04-03
    Sponsor Name:
    Full Title: Catheter Ablation compared with Pharmacological Therapy for Atrial Fibrillation – the CAPTAF trial
    Medical condition: To study the effect of catheter ablation (using CE marked products) on the quality of life an in patients with atrial fibrillation depsite treatment with conevntional antiarrhythmic medical therapy...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066664 Recurrent symptomatic atrial fibrillation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005087-93 Sponsor Protocol Number: Start Date*: 2006-11-17
    Sponsor Name:East Kent Hospitals NHS Trust
    Full Title: A randomized double blind placebo controlled trial of Memantine in the treatment of Agitation in Alzheimers Dementia
    Medical condition: Alzheimers dementia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002890-37 Sponsor Protocol Number: 1 Start Date*: 2017-02-07
    Sponsor Name:Esther Aleo Lujan
    Full Title: Double-blind randomized clinical trial to compare presurgery anxiolysis in children treated with hydroxyzine versus non-pharmacological intervention (distractoria technique clown).
    Medical condition: Presurgery anxiety
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004873 10040760 Situational anxiety LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-002289-62 Sponsor Protocol Number: ST200-SSMA-14-001 Start Date*: 2014-09-11
    Sponsor Name:SIGMA-TAU, Industrie Farmaceutiche Riunite S.p.A.
    Full Title: Electroneurographic and clinical evaluation in patients with mild / moderate Carpal Tunnel Syndrome , following conservative pharmacological treatment with Nicetile®.
    Medical condition: Carpal Tunnel Syndrome
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10007697 Carpal tunnel syndrome PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000287-17 Sponsor Protocol Number: RC12-01 Start Date*: 2012-05-21
    Sponsor Name:FONDAZIONE SANTA LUCIA
    Full Title: PROMOTION OF FUNCTIONAL RESTORATION THROUGH PHARMACOLOGICAL MODULATION OF BRAIN PLASTICITY WITH AMINOPYRIDINE IN PATIENTS WITH MULTIPLE SCLEROSIS STUDIED BY FUNCTIONAL MRI
    Medical condition: Patients with MS, without relevant medical conditions, with right upper limb impairment assessed by a hand dexterity test will be included.Patients will be in a non-active phase of the disease and ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10028053 MS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001291-71 Sponsor Protocol Number: W005PS0208_1 Start Date*: 2008-07-23
    Sponsor Name:University of Wuerzburg
    Full Title: Electrophysiological correlates of putative endophenotypes of attention-deficit / hyperactivity disorder (ADHD)
    Medical condition: Attention-deficit hyperactivity disorder (ADHD)
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001066-14 Sponsor Protocol Number: DENERVHTA Start Date*: 2012-07-17
    Sponsor Name:Consorci Mar Parc de salut de Barcelona ( Parc de Salut Mar)
    Full Title: Sympathetic renal denervation versus increment of pharmacological treatment in resistant arterial hypertension
    Medical condition: subjects with resistant hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-004548-31 Sponsor Protocol Number: HUB-PSI-CAMAD Start Date*: 2020-04-18
    Sponsor Name:Cinto Segalàs
    Full Title: A RANDOMIZED, CONTROLLED, OPEN AND UNICENTRIC PHASE II CLINICAL TRIAL, WITH TWO PARALLEL GROUPS, TO EVALUATE THE ANTIDEPRESSANT EFFICACY OF PSYCHOTHERAPY AND CITALOPRAM IN WOMEN DIAGNOSED WITH BREA...
    Medical condition: Female patients diagnosed with breast cancer who, during the first year following the diagnosis of oncological disease, have affective symptomatology that meets DSM-V criteria for major depression.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10037175 - Psychiatric disorders 10057840 Major depression PT
    21.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057654 Breast cancer female PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-004350-91 Sponsor Protocol Number: TAK-375/EC301 Start Date*: 2005-11-10
    Sponsor Name:Takeda Europe R&D Centre Ltd
    Full Title: A multicentre, randomised, double-blind, double-dummy, placebo-controlled study to evaluate the safety and efficacy of ramelteon compared to placebo with zopiclone as a reference arm in adults with...
    Medical condition: chronic insomnia
    Disease: Version SOC Term Classification Code Term Level
    8 10053851 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) AT (Completed) FI (Completed) IT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002755-42 Sponsor Protocol Number: 1069/12 Start Date*: 2012-11-06
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: OBESITY AND ASPIRIN RESPONSIVENESS
    Medical condition: OBESITY
    Disease: Version SOC Term Classification Code Term Level
    15.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-000483-29 Sponsor Protocol Number: Wada_2012 Start Date*: 2013-07-17
    Sponsor Name:Bispebjerg Hospital
    Full Title: The influence of exercise and hydration to the pharmacological response to inhaled terbutalin and salbutamol in men
    Medical condition: To investigate the pharmacokinetic effect of the medicine under physical work in healthy men
    Disease: Version SOC Term Classification Code Term Level
    16.1 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-000230-39 Sponsor Protocol Number: FOG 2006 Start Date*: 2008-04-14
    Sponsor Name:Endocrine Society of Czech Republic
    Full Title: Protective effect of gonadoliberin analogues on endocrine and reproduction ovarian function during antitumour treatment in young girls and women in fertile period: Project of pharmacological gonada...
    Medical condition: The patient with diagnosis: Hodgkin disease and leukaemia. Patients starting at adolescence (B3 - B4 for breast development accordig Tanner criteria) till 34 years be included. ...
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001659-42 Sponsor Protocol Number: ANTITROMBINA Start Date*: 2020-04-18
    Sponsor Name:Fundación para la Investigación Biomédica de Córdoba
    Full Title: Pilot study of antithrombin as prophylaxis of acute respiratory distress syndrome in patients with COVID-19
    Medical condition: Confirmed SARS-CoV-2 respiratory infection with poor prognostic factors
    Disease: Version SOC Term Classification Code Term Level
    20.0 10021881 - Infections and infestations 10051905 Coronavirus infection LLT
    20.1 10021881 - Infections and infestations 10061982 Severe acute respiratory syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-000650-21 Sponsor Protocol Number: PHARMADIPOAGE Start Date*: 2018-10-31
    Sponsor Name:Universidad Autónoma de Madrid
    Full Title: CLINICAL TRIAL FOR EVALUATION OF THE ADIPOQUINAS: NEW PHARMACOLOGICAL TARGETS TO PREVENT VASCULAR AGING
    Medical condition: PREDIABETES
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004861 10065542 Prediabetes LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-001327-41 Sponsor Protocol Number: IMIB-RMV-2021-02 Start Date*: 2021-07-12
    Sponsor Name:Fundación para la formación e investigación sanitarias de la Región de Murcia
    Full Title: Withdrawal of pharmacological treatment in patients responding to cardiac resynchronization therapy: Open and randomized study
    Medical condition: Heart failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003745-14 Sponsor Protocol Number: D1448C00005 Start Date*: 2006-01-13
    Sponsor Name:AstraZeneca AB
    Full Title: A Multi-centre, Double-blind, Randomised Withdrawal, Parallel-group, Placebo-controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Sustained Release (Seroquel SR®) as Monothe...
    Medical condition: Maintenance treatment of patients with Major Depressive Disorder
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed) FI (Completed) SK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000206-36 Sponsor Protocol Number: DOPA1 Start Date*: 2014-10-27
    Sponsor Name:
    Full Title: DRD4 genotype as a moderator of L-Dopa intervention effects on parent-related neurocognitive processes, behaviors, and attitudes: A micro-trial of differential susceptibility to pharmacological int...
    Medical condition: There are no medical conditions or diseases under investigation.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-002372-36 Sponsor Protocol Number: 2022-16039 Start Date*: 2024-01-02
    Sponsor Name:Wageningen Research Stichting
    Full Title: The CanISleepinMS Study: Effect of cannabidiol (CBD) on sleep quality in patients with multiple sclerosis, a series of 15 randomised, placebo controlled N-of-1 trials
    Medical condition: Insomnia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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