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Clinical trials for Physical activity

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,725 result(s) found for: Physical activity. Displaying page 1 of 87.
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    EudraCT Number: 2016-003085-32 Sponsor Protocol Number: CLCZ696B3301 Start Date*: 2016-11-14
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A multi-center, prospective, randomized, double-blind study to assess the impact of sacubitril/valsartan vs. enalapril on daily physical activity using a wrist worn actigraphy device in adult chron...
    Medical condition: Heart Failure with reduced ejection fraction (HFrEF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) LT (Completed) SE (Completed) EE (Completed) DK (Completed) LV (Completed) BE (Completed) ES (Completed) FI (Completed) FR (Completed) BG (Completed) NL (Completed) IS (Completed) GR (Completed) CZ (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-002600-18 Sponsor Protocol Number: 43/2007/O/Sper Start Date*: 2007-06-05
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: EVALUATION OF THE RELATIONSHIP BETWEEN INFLAMMATION-PHYSICAL ACTIVITY AND THE ACTIVITY OF THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
    Medical condition: Abdominal obesity with metabolic syndrome
    Disease: Version SOC Term Classification Code Term Level
    6.1 10052066 PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002232-82 Sponsor Protocol Number: KIH18001 Start Date*: 2019-07-25
    Sponsor Name:Karolinska Institutet
    Full Title: Downstream targets of SSRI effect in treatment of Major Depressive Disorder
    Medical condition: Major depressive disorder (MDD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2017-000216-42 Sponsor Protocol Number: AC-065A404 Start Date*: 2017-07-11
    Sponsor Name:Actelion Pharmaceuticals Ltd
    Full Title: A multi-center, double-blind, placebo-controlled, Phase 4 study in patients with pulmonary arterial hypertension to assess the effect of selexipag on daily life physical activity and patient’s self...
    Medical condition: Pulmonary arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) IE (Completed) SE (Completed) DE (Completed) AT (Completed) PT (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2020-000204-11 Sponsor Protocol Number: NN9536-4578 Start Date*: 2021-01-11
    Sponsor Name:Novo Nordisk A/S
    Full Title: Effect of subcutaneous semaglutide 2.4 mg once-weekly compared to placebo in subjects with obesity and knee osteoarthritis
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DK (Completed) SE (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2015-000581-58 Sponsor Protocol Number: BioBioV4.0 Start Date*: 2015-10-14
    Sponsor Name:Revmatologicky ustav Praha
    Full Title: A Randomized, Biomarker Trial to Predict Therapeutic Responses of Patients with Rheumatoid Arthritis to a Specific Biologic Mode of Action
    Medical condition: Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-002836-30 Sponsor Protocol Number: 22218MFPF-Weave Start Date*: 2023-03-15
    Sponsor Name:Vrije Universiteit Brussel
    Full Title: Investigating fundamental mechanisms of mental and physical fatigue using neurotransmitter reuptake inhibitors and electroencephalography: a randomized counterbalanced crossover trial
    Medical condition: Acute mental and physical fatigue in healthy participants
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-005092-13 Sponsor Protocol Number: MO42623 Start Date*: Information not available in EudraCT
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: A MULTICENTER, OPEN-LABEL PHASE IV STUDY TO EVALUATE OVERALL HEALTH, PHYSICAL ACTIVITY, AND JOINT OUTCOMES, IN PARTICIPANTS AGED ≥ 13 AND < 70 YEARS WITH SEVERE OR MODERATE HEMOPHILIA A WITHOUT FVI...
    Medical condition: Severe or Moderate Hemophilia A
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10053753 Hemophilia A without inhibitors LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Prematurely Ended) DE (Trial now transitioned) ES (Ongoing) IT (Trial now transitioned) HU (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-001552-30 Sponsor Protocol Number: PRED-D-TRIAL2015 Start Date*: 2015-10-13
    Sponsor Name:Steno Diabetes Center A/S
    Full Title: Effect of dapagliflozin, metformin and physical activity on glucose variability, body composition and cardiovascular risk in pre-diabetes (The PRE-D Trial) - A randomised, parallel, open-label, int...
    Medical condition: Pre-diabetes
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004861 10065542 Prediabetes LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-005056-96 Sponsor Protocol Number: TRAWADA2015 Start Date*: 2016-05-31
    Sponsor Name:Daniel Sanabria Lucena
    Full Title: Use of tramadol in healthy volunteers. Effects on physical performance and sustained attention in cycling.
    Medical condition: Sport doping
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004873 10076471 Drug doping LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-002435-15 Sponsor Protocol Number: FiHM003 Start Date*: 2017-08-10
    Sponsor Name:Fundación de Investigación HM Hospitales
    Full Title: Pilot study to assess physical exercise intervention in neoadjuvant treatment with nab-paclitaxel in patients with triple negative breast cancer
    Medical condition: Supervised exercise regimen given during neoadjuvant chemotherapy for triple negative breast cancer patients.
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-001710-37 Sponsor Protocol Number: NL73727 Start Date*: 2021-05-26
    Sponsor Name:Academisch Medisch Centrum
    Full Title: Intravenous immunoglobulin and prednisone vs. prednisone in newly diagnosed myositis: a double blind randomized clinical trial.
    Medical condition: idiopathic inflammatory myopathies
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-006352-36 Sponsor Protocol Number: VPN-10-18 Start Date*: 2013-04-11
    Sponsor Name:Lithuanian University of Health Sciences, Endocrinology Department
    Full Title: Obesity in children and adolescents: complications, associated risks and early intervention (lifestyle changes and insulin sensitivity improving medicine (metformin) effectiveness and safety evalua...
    Medical condition: The aim of our study is to establish the effectivenes and safety of metformin use in pediatric obese population; to assess the prevalence of insulin resistance, metabolic syndrome, polycystic ovary...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    14.1 10027433 - Metabolism and nutrition disorders 10033307 Overweight PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-020513-87 Sponsor Protocol Number: Q03-09-01 Start Date*: 2010-09-02
    Sponsor Name:FIDIA
    Full Title: A randomized, placebo-controlled, double-blind study on the intensity and duration of efficacy of sodium hyaluronate therapy (500-730 KDa) (HYALGAN) in the conservative treatment of Achilles tendin...
    Medical condition: Achilles tendinopathy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000433 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2022-001563-26 Sponsor Protocol Number: NCT05355337 Start Date*: 2022-10-03
    Sponsor Name:Region Skåne
    Full Title: Pramipexole for Anhedonic Depression (PRIME-PRAXOL)
    Medical condition: The effect of nine weeks of treatment with the dopamine agonist Pramipexole in patients with depression with clinically significant anhedonia will be evaluated with symptom rating scales, blood and...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10002511 Anhedonia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002611-29 Sponsor Protocol Number: 82050 Start Date*: 2023-06-12
    Sponsor Name:Leiden University Medical Center
    Full Title: DEnosumab for the treatment of FIbrous Dysplasia/McCune-Albright Syndrome in adults (DeFiD): a randomized double-blind placebo-controlled trial
    Medical condition: Fibrous Dysplasia/ McCune Albright Syndrome
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003473-34 Sponsor Protocol Number: NN9536-4376 Start Date*: 2018-05-03
    Sponsor Name:Novo Nordisk A/S
    Full Title: Effect and safety of semaglutide 2.4 mg once-weekly in subjects with overweight or obesity who have reached target dose during run-in period
    Medical condition: Obesity
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) NL (Completed) PT (Completed) DK (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-001238-89 Sponsor Protocol Number: FACE Start Date*: 2016-06-15
    Sponsor Name:Consorci Mar Parc de Salut de Barcelona (Parc de Salut MAR)
    Full Title: IRON DEFICIENCY IN PATIENTS WITH COPD: IMPACT OF TOPPING WITH IRON CARBOXYMALTOSE. FACE STUDY (ASSESSMENT IN PATIENTS WITH FERINJECT AND IRON DEFICIENCY COPD TO IMPROVE EXERCISE TOLERANCE)
    Medical condition: Iron deficiency in Chronic obstructive pulmonary disease patients (COPD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005139-61 Sponsor Protocol Number: EB064 Start Date*: 2006-10-24
    Sponsor Name:Emotional Brain
    Full Title: Neural correlates of sexual arousal during treatment of testosterone combined with sildenafil in healthy female subjects with FSD. Effects of differing levels of attentional engagement on neural co...
    Medical condition: Hypoactive sexual desire disorder and female sexual arousal disorder
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-002964-22 Sponsor Protocol Number: AGO/2013/009 Start Date*: 2013-12-10
    Sponsor Name:Ghent University Hospital
    Full Title: Influence of aromatase inhibitors on insulin sensitivity, liver and hart function in obese men
    Medical condition: Influence of aromatase inhibitors on insulin sensitivity, liver and hart function in obese men
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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