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Clinical trials for Prostaglandin analogue

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44363   clinical trials with a EudraCT protocol, of which   7387   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    16 result(s) found for: Prostaglandin analogue. Displaying page 1 of 1.
    EudraCT Number: 2010-022433-29 Sponsor Protocol Number: LATANO-2 Start Date*: 2010-10-13
    Sponsor Name:Aarhus University Hospital, Department of Ophthalmology
    Full Title: Pharmacological intervention on diabetic retinopathy with PGF
    Medical condition: Diabetic retinopathy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2004-002051-13 Sponsor Protocol Number: PANN3006 Start Date*: 2005-08-17
    Sponsor Name:Imperial College, London
    Full Title: A randomised double-blind placebo-controlled trial of oral misoprostol for cervical priming before outpatient hysteroscopy
    Medical condition: Abnormal uterine bleeding (hysteroscopy to investigate and treatment of abnormal uterine bleeding)
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2014-000540-15 Sponsor Protocol Number: SPON1266-14 Start Date*: 2014-05-01
    Sponsor Name:Cardiff University
    Full Title: Prostaglandin F2-alpha eye drops (Bimatoprost) in thyroid eye disease: a randomised controlled double blind crossover trial
    Medical condition: Graves' ophthalmopathy
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004853 10057889 Graves' ophthalmopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-000438-16 Sponsor Protocol Number: LT2347-PIV-02/20 Start Date*: 2020-07-29
    Sponsor Name:Laboratoires Théa S.A.S
    Full Title: RANDOMIZED SINGLE-BLIND CLINICAL TRIAL TO STUDY THE TOLERABILITY, EFFICACY, QUALITY OF LIFE, AND ADHERENCE OF FIXAPROST® COMPARED TO GANFORT® P IN PATIENTS WITH OPEN-ANGLE GLAUCOMA AND/OR OCULAR HY...
    Medical condition: Open angle glaucoma and ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000580-41 Sponsor Protocol Number: LTG1030-PIV-12/07 Start Date*: 2008-04-02
    Sponsor Name:Laboratoires THEA
    Full Title: Safety and Efficacy assessment of Geltim LP ® 1 mg/g (unpreserved Timolol gel – TG1030) in ocular hypertensive or glaucomatous patients stabilized by Xalatan® with ocular intolerance signs
    Medical condition: The main objective is to assess the safety and the efficacy, in intra ocular pressure, of Geltim LP ® 1 mg/g (0.1% unpreserved timolol maleate gel) in glaucomatous patients initially treated and st...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10018304 Glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-003187-31 Sponsor Protocol Number: GN09CA403 Start Date*: 2015-03-19
    Sponsor Name:NHS Greater Glasgow & Clyde
    Full Title: Misoprostol for the Healing of Small Bowel Ulceration in Patients with Obscure Blood Loss while Taking Low-Dose Aspirin or Non-Steroidal Anti-inflammatory Drugs [MASTERS Trial]
    Medical condition: Small bowel ulcers associated with iron deficiency anaemia or obscure blood loss in patients using aspirin or non-steroidal anti-inflammatory drugs
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10066761 Acute anaemia LLT
    20.0 10005329 - Blood and lymphatic system disorders 10057220 Acute post haemorrhagic anaemia LLT
    20.0 10005329 - Blood and lymphatic system disorders 10002034 Anaemia PT
    20.0 10005329 - Blood and lymphatic system disorders 10002034 Anaemia PT
    20.1 10005329 - Blood and lymphatic system disorders 10002083 Anaemia- Hypochromic microcytic picture LLT
    20.0 10005329 - Blood and lymphatic system disorders 10002062 Anaemia iron deficiency LLT
    20.0 10022891 - Investigations 10014816 Endoscopy small intestine PT
    20.0 10022891 - Investigations 10014816 Endoscopy small intestine PT
    20.1 10022891 - Investigations 10014817 Endoscopy small intestine abnormal PT
    20.1 10022891 - Investigations 10014818 Endoscopy small intestine normal PT
    20.1 10017947 - Gastrointestinal disorders 10041133 Small intestine ulcer PT
    20.1 10017947 - Gastrointestinal disorders 10041133 Small intestine ulcer PT
    20.1 10017947 - Gastrointestinal disorders 10041134 Small intestine ulcer haemorrhagic LLT
    20.1 10017947 - Gastrointestinal disorders 10055339 Small intestine ulcer hemorrhagic LLT
    20.0 10017947 - Gastrointestinal disorders 10045335 Ulcer small intestine LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-005314-29 Sponsor Protocol Number: QTM/OMN-0115 Start Date*: 2016-03-02
    Sponsor Name:OMNIVISION GmbH
    Full Title: Randomized, open-label, two parallel group clinical trial, conducted under blinding evaluator conditions to compare the efficacy and tolerability of preservative-free formulation of Latanoprost 50µ...
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002501-45 Sponsor Protocol Number: EMD-06-02 Start Date*: 2008-03-14
    Sponsor Name:Alcon Laboratories Inc.
    Full Title: Phase IV randomised double masked clinical trial: Assessing morning versus evening dosing of a fixed dose combination of Travoprost 0.004% / Timolol Maleate 0.5% in patients with primary open angle...
    Medical condition: Open - angle glaucoma or ocular hypertension.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-013178-42 Sponsor Protocol Number: C-09-032 Start Date*: 2009-07-31
    Sponsor Name:Alcon Research, Ltd.
    Full Title: A Twelve-Month Open-Label Safety Study of Polyquaternium-Preserved DuoTrav APS Dosed Once Daily in Patients with Open-Angle Glaucoma or Ocular Hypertension
    Medical condition: Open-Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    12.0 10030043 Ocular hypertension LLT
    12.0 10030348 Open angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) LV (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-000736-15 Sponsor Protocol Number: GLH694-P001 Start Date*: 2015-09-14
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Additive Effect of Twice Daily Brinzolamide 1% /Brimonidine 0.2% Fixed Dose Combination as an Adjunctive Therapy to a Prostaglandin Analogue
    Medical condition: Ocular Hypertension Open-angle Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    20.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) GB (Completed) FR (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2010-021039-14 Sponsor Protocol Number: S001-2010 Start Date*: 2010-08-19
    Sponsor Name:Tampere University, Faculty of Medicine, Department of Ophthalmology
    Full Title: An open-label, phase IV, pilot study, to evaluate confocal microscopic findings of cornea, ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switching from latan...
    Medical condition: Ocular Hypertension (OH) or Open-Angle Glaucoma (OAG); primary open-angle glaucoma [POAG] or capsular glaucoma.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030043 Ocular hypertension LLT
    12.1 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005339-15 Sponsor Protocol Number: QTM/OMN0211 Start Date*: 2012-02-03
    Sponsor Name:Omnivision GmbH
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of the Fixed Combin...
    Medical condition: Primary open angle glaucoma or intraocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.0 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-004763-19 Sponsor Protocol Number: FARM7CZ54W Start Date*: 2009-06-03
    Sponsor Name:AZIENDA OSPEDALIERA SPEDALI CIVILI DI BRESCIA
    Full Title: EFFICACY AND SAFETY OF TOPICALLY APPLIED PROSTAGLANDIN ANALOGUE AND CARBONIC ANHYDRASE INHIBITOR FOR THE TREATMENT OF PAEDIATRIC GLAUCOMA REFRACTORY TO SURGICAL PROCEDURES
    Medical condition: Children affected to primary Paediatric Glaucoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10064033 Infantile glaucoma LLT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000026-22 Sponsor Protocol Number: QTM/OMN0112 Start Date*: 2012-07-23
    Sponsor Name:Omnivision GmbH
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of Travoprost 40 µg...
    Medical condition: Primary open angle glaucoma or intraocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10030043 Ocular hypertension PT
    14.1 10015919 - Eye disorders 10036719 Primary open angle glaucoma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-011036-36 Sponsor Protocol Number: C-01-78 Start Date*: 2009-05-07
    Sponsor Name:Alcon Research, Ltd.
    Full Title: Estudio multicéntrico de la pigmentación en la red trabecular después de dos años de tratamiento con TRAVATAN 0,004% solución oftálmica. A multicenter study of the pigmentation in the trabecular me...
    Medical condition: Glaucoma de angulo abierto o hiperstensión ocular. Open-angle glaucoma or ocular hypertension
    Disease: Version SOC Term Classification Code Term Level
    9.1 10030348 Open angle glaucoma LLT
    9.1 10030043 Ocular hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000044-10 Sponsor Protocol Number: QTM/OMN0114 Start Date*: 2015-03-30
    Sponsor Name:OMNIVISION
    Full Title: Open, Observer-blind, two Parallel Group, Randomized, Multicentric Clinical Phase III Trial on the Comparison of Efficacy and Tolerability of a New Preservative-free Formulation of the Fixed Combin...
    Medical condition: Open Angle Glaucoma or Ocular Hypertension
    Disease: Version SOC Term Classification Code Term Level
    18.0 10015919 - Eye disorders 10018307 Glaucoma and ocular hypertension HLGT
    18.0 10015919 - Eye disorders 10030348 Open angle glaucoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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