Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Quetiapine XR (Seroquel XR)

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44337   clinical trials with a EudraCT protocol, of which   7367   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    16 result(s) found for: Quetiapine XR (Seroquel XR). Displaying page 1 of 1.
    EudraCT Number: 2007-004246-32 Sponsor Protocol Number: D1443L00031 Start Date*: 2007-12-05
    Sponsor Name:ASTRAZENECA
    Full Title: Comparison of Quetiapine Extended-Release (Seroquel XR™ ) and Risperidone in the treatment of depressive symptoms, in schizophrenic or schizoaffective patients: A randomized, open label, flexible-d...
    Medical condition: Patient with schizophrenia or schizoaffective disorder with depressive symptoms
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039620 Schizoaffective and schizophreniform disorders HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-007190-20 Sponsor Protocol Number: D144AC00003 Start Date*: 2009-12-14
    Sponsor Name:AstraZeneca AB
    Full Title: An International, Multicenter, Double-blind, Randomized, Placebo-controlled, Phase IV Study of the Safety and Efficacy of Lithium versus Placebo as an add on to SEROQUEL XR™ (Quetiapine Fumarate) i...
    Medical condition: Acut mania in subjects with bipolar I disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10004939 Bipolar I disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-001371-30 Sponsor Protocol Number: D1443L00051 Start Date*: 2009-02-16
    Sponsor Name:Universitätsklinikum Münster
    Full Title: Anxiolytic effects of single-dose quetiapine XR administration on clinical symptoms and amygdala activation during exposure in patients with simple phobia
    Medical condition: simple phobia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-020579-21 Sponsor Protocol Number: D1443L00082 Start Date*: 2010-08-19
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase IV Prospective, Double-blind, Double-dummy, Randomised, Crossover Study to Assess the Impact on Daily Cognitive Functioning of Quetiapine Fumarate Immediate Release (Seroquel IR®) Dosed twi...
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10039626 Schizophrenia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed) ES (Completed) IT (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-000088-12 Sponsor Protocol Number: D1443C00012 Start Date*: 2008-08-18
    Sponsor Name:Department of Psychiatry, LMU Munich
    Full Title: A prospective, single-blinded (rater-blinded), randomized, parallel group study of the efficacy of Quetiapine XR in the treatment of patients with Acute Stress Disorder (DSM-VI 308.3)
    Medical condition: 40 patients with Acute Stress Disorder will be recruited within 2 years. The subjects must meet DSM- IV criteria for acute stress disorder (no acute suicidality) and will be treated with Quetiapine...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-007127-40 Sponsor Protocol Number: D1443L00048 Start Date*: 2008-09-10
    Sponsor Name:Astra ZenecaGmbH
    Full Title: CARE II - Evaluation of treatment outcomes in schizophrenic patients taking part in the integrated care program - a single-country, multi-centre phase IV study
    Medical condition: Symptomatic schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder or psychotic disorder not otherwise specified
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-004740-79 Sponsor Protocol Number: D1443L00039 Start Date*: 2008-06-10
    Sponsor Name:AstraZeneca GmbH
    Full Title: A One-Year Randomized, Prospective, Parallel, Open Comparison of Subjective Well-being in Schizophrenic Out-patients Treated with Quetiapine XR (SEROQUEL Prolong®) or Oral Risperidone at Flexible D...
    Medical condition: Schizophrenia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) FI (Completed) BE (Completed) PT (Completed) IT (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2008-000908-91 Sponsor Protocol Number: D1443L00044 Start Date*: 2008-10-16
    Sponsor Name:AstraZeneca AB
    Full Title: A randomised, 6-week, multicentre, open-label, rater-blinded parallelgroup study comparing Quetiapine extended release monotherapy and augmentation with Lithium augmentation in patients with Treatm...
    Medical condition: Treatment resistant depression
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057840 Major depression PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) SK (Completed) AT (Completed) HU (Completed) DK (Prematurely Ended) BE (Completed) GB (Completed) IT (Completed) PT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2005-001217-17 Sponsor Protocol Number: Max-Planck-Institute of Psychiatry Start Date*: 2005-09-12
    Sponsor Name:Max-Planck-Institute of Psychiatry
    Full Title: Comparison of venlafaxine augmentation with lamotrigine, quetiapine, or placebo in treatment resistant depression
    Medical condition: Treatment resistant depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001520-12 Sponsor Protocol Number: D1443C00013 Start Date*: 2008-01-11
    Sponsor Name:Unidade de Investigação em Saúde Mental e Psiquiatria do Centro Hospitalar Conde de Ferreira
    Full Title: Efficacy and distinctive effects of atypical antipsychotics on cognitive symptoms in dual diagnosis – A phase IIIb, randomized, open-labelled study to evaluate the cognitive effects of quetiapine X...
    Medical condition: Patients with both schizophrenia and substance abuse disorder
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: PT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-003948-67 Sponsor Protocol Number: 331-12-282 Start Date*: 2013-05-08
    Sponsor Name:Otsuka Pharmaceutical Development & Commercialization,Inc
    Full Title: A Phase 3, Multicenter, Randomized, Double-blind, Placebo- and Active Comparator-controlled Trial of Flexible-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With M...
    Medical condition: Major Depressive Disorder (MDD)
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004873 10025454 Major depressive disorder, recurrent episode LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SK (Completed) FR (Completed) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-003984-38 Sponsor Protocol Number: D1050233 Start Date*: 2009-06-02
    Sponsor Name:Dainippon Sumitomo Pharma America Ltd
    Full Title: A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO- AND ACTIVE COMPARATOR CONTROLLED CLINICAL TRIAL TO STUDY THE EFFICACY AND SAFETY OF TWO DOSES OF LURASIDONE IN ACUTELY PSYCHOTIC SUBJECTS WITH SCHIZOPHR...
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039626 Schizophrenia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: RO (Completed)
    Trial results: View results
    EudraCT Number: 2008-003331-20 Sponsor Protocol Number: D11443C00027 Start Date*: Information not available in EudraCT
    Sponsor Name:Technical University Munich, Klinikum rechts der Isar
    Full Title: Effect of quetiapine XR on sleep in patients with major depression, as compared with mirtazapine
    Medical condition: During the past years, growing evidence of a pronounced antidepressant effect of quetiapine has been demonstrated in several studies; in the same time, quetiapine turned out to have sleep-promoting...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012399 Depressive disorder LLT
    9.1 10025453 Major depressive disorder NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-002259-40 Sponsor Protocol Number: SEP361-304 Start Date*: 2021-06-03
    Sponsor Name:Sunovion Pharmaceuticals Inc.
    Full Title: A Randomized, Double-blind, Active Comparator-Controlled Study to Evaluate the Long-term Safety and Tolerability of SEP-363856 in Subjects with Schizophrenia
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004873 10039632 Schizophrenia NOS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: RO (Ongoing)
    Trial results: View results
    EudraCT Number: 2009-011911-19 Sponsor Protocol Number: QUE/09 Start Date*: Information not available in EudraCT
    Sponsor Name:Ludwig-Maximilian-University of Munich, Department of Psychiatry
    Full Title: Impact of quetiapine prolong and escitalopram on the hypothalamic-pituitary-adrenocortical (HPA)-axis activity in depressed patients
    Medical condition: In this study, patients suffering from unipolar depression are investigated. 40 unipolar depressed inpatients (age 18-65) enter the study after the procedure has been fully explained and written in...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012378 Depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013028-21 Sponsor Protocol Number: ------ Start Date*: 2009-10-16
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALE
    Full Title: USE OF CLINICAL AND INTERMEDIATE PHENOTYPES TO ASSESS RESPONSE TO QUETIAPINE: THE ROLE OF PUTATIVE CAUSATIVE GENES
    Medical condition: schizophrenia using the Structured Clinical Interview for Diagnosis (SCID) for the Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV);
    Disease: Version SOC Term Classification Code Term Level
    9.1 10037175 SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Thu May 22 07:57:35 CEST 2025 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA