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Clinical trials for Reperfusion

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    157 result(s) found for: Reperfusion. Displaying page 1 of 8.
    1  2  3  4  5  6  7  8  Next»
    EudraCT Number: 2008-004613-10 Sponsor Protocol Number: IRIVITC2008 Start Date*: 2008-09-12
    Sponsor Name:University College Hospital Galway
    Full Title: The role of the antioxidants ascorbic acid and n-acetylcysteine in the attenuation of ischaemia reperfusion injury in a human model
    Medical condition: Ischaemia reperfusion injury
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063837 Reperfusion injury LLT
    9.1 10063837 Reperfusion injury PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005343-27 Sponsor Protocol Number: Metformin-FMD001 Start Date*: 2012-01-27
    Sponsor Name:Radboud University Nijmegen Medical Centre
    Full Title: Can metformin prevent endothelial ischemia and reperfusion injury? The Metformin-FMD trial.
    Medical condition: ischemia and reperfusion injury endothelial dysfunction
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10063837 Reperfusion injury PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014831-18 Sponsor Protocol Number: fmd/01 Start Date*: 2009-09-25
    Sponsor Name:RUNMC
    Full Title: Short term statin treatment and endothelial dysfunction due to ischemia and reperfusion injury
    Medical condition: ischemia and reperfusion injury endothelial dysfunction
    Disease: Version SOC Term Classification Code Term Level
    12.0 10063837 Reperfusion injury LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022393-13 Sponsor Protocol Number: Helium-MI Start Date*: 2010-11-24
    Sponsor Name:Academical Medical Center, University of Amsterdam
    Full Title: Does helium protect the heart against ischaemia-reperfusion damage in patients with acute myocardial infarction?
    Medical condition: Acute myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000891 Acute myocardial infarction LLT
    12.1 10051624 Myocardial reperfusion injury LLT
    12.1 10063837 Reperfusion injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-000623-73 Sponsor Protocol Number: LIDO Start Date*: 2016-09-29
    Sponsor Name:FUNDACIÓN INVESTIGACIÓN BIOMÉDICA HOSPITAL PUERTA DE HIERRO
    Full Title: LIDOCAINE IN ISCHEMIA-REPERFUSION INJURY FROM MICROSURGICAL BREAST RECONSTRUCTION. RANDOMISED UNICENTRIC, DOUBLE-BLIND, CLINICAL, CONTROLLED TRIAL.
    Medical condition: Ischemia-reperfusion injury from breast reconstruction microsurgical flaps.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001581-20 Sponsor Protocol Number: IRRB/72/14 Start Date*: 2018-02-08
    Sponsor Name:ISTITUTO MEDITERRANEO PER I TRAPIANTI E TERAPIE AD ALTA SPECIALIZZAZIONE - ISMETT
    Full Title: THE ADDITION OF SIMVASTATIN ADMINISTRATION TO COLD STORAGE SOLUTION OF EXPLANTED WHOLE LIVER GRAFTS FOR FACING ISCHEMIA/REPERFUSION INJURY IN AN AREA WITH LOW RATE OF DECEASED DONATION. A MONOCENT...
    Medical condition: ISCHEMIC REPERFUSION INJURY AFTER LIVER TRANSPLANTATION: HEPATIC ISCHEMIA AND REPERFUSION INJURY REPRESENTS THE MAIN UNDERLYING MECHANISM FOR GRAFT DYSFUNCTION, AND FAILURE, POST-TRANSPLANTATION. H...
    Disease: Version SOC Term Classification Code Term Level
    21.1 10047065 - Vascular disorders 10063837 Reperfusion injury PT
    20.0 10042613 - Surgical and medical procedures 10024714 Liver transplant PT
    20.1 10022117 - Injury, poisoning and procedural complications 10058060 Graft complication PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002312-27 Sponsor Protocol Number: 13-031 Start Date*: 2013-08-14
    Sponsor Name:Zealand Pharma
    Full Title: A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Trial to Assess Clinical Efficacy and Safety of Danegaptide in Patients with ST-Elevation Myocardial Infarction undergoing Primary Per...
    Medical condition: The treatment of acute myocardial infarction, AMI is aimed at enabling the return of blood flow to the ischemic myocardium, thereby limiting the size of the infarct. However the reperfusion by itse...
    Disease: Version SOC Term Classification Code Term Level
    16.1 10047065 - Vascular disorders 10063837 Reperfusion injury PT
    16.1 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2018-003640-23 Sponsor Protocol Number: IRRB/05/18 Start Date*: 2019-05-29
    Sponsor Name:ISTITUTO MEDITERRANEO PER I TRAPIANTI E TERAPIE AD ALTA SPECIALIZZAZIONE - ISMETT
    Full Title: USE OF HEPATITIS C+ DONORS FOR SOLID ORGAN TRANSPLANTATION IN A GEOGRAPHICAL AREA WITH HCV+ ENDEMIC INFECTION AND WITH A LOW-RATE CADAVERIC ORGAN DONOR AVAILABILITY. A PHASE II OPEN, MONOCENTRIC CL...
    Medical condition: USE OF POSITIVE DONORS FOR INFECTION OF THE HEPATITIS VIRUS FOR THE TRANSPLANTATION OF SOLID ORGANS IN AN ENDEMIC AREA FOR HEPATITIS C WITH LOW RATE OF DONATIONS FROM CADAVERS: OPEN PHASE II CLINI...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10024714 Liver transplant PT
    21.1 10047065 - Vascular disorders 10063837 Reperfusion injury PT
    20.1 10022117 - Injury, poisoning and procedural complications 10058060 Graft complication PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-001922-24 Sponsor Protocol Number: 120541 Start Date*: 2013-07-12
    Sponsor Name:University College London (UCL)
    Full Title: The effect of remote ischaemic preconditioning and glyceryl trinitrate on peri-operative myocardial injury in cardiac bypass surgery patients (ERIC-GTN study)- a four arm randomised controlled trial
    Medical condition: We are investigating the phenomenon of ischaemic-reperfusion injury. Reperfusion of the ischaemic myocardium is known to cause further myocardial damage. We wish to investigate the phenomenon of Re...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-006034-18 Sponsor Protocol Number: 06004 Start Date*: 2007-05-21
    Sponsor Name:Medicure International Inc.
    Full Title: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTI-CENTER STUDY TO EVALUATE THE CARDIOPROTECTIVE EFFECTS OF MC-1 IN PATIENTS UNDERGOING HIGH-RISK CORONARY ARTERY BYPASS GRAFT (CABG) SURGERY
    Medical condition: For treatment to reduce cardiovascular events associated with ischemic damage and/or ischemia-reperfusion injury in patients undergoing CABG surgery.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10051624 Myocardial reperfusion injury LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001089-33 Sponsor Protocol Number: 2007-001089-33 Start Date*: 2008-09-23
    Sponsor Name:University Medical Center Groningen, dept. of Cardiology [...]
    1. University Medical Center Groningen, dept. of Cardiology
    2. University Medical Center Nijmegen, dept. of Pharmacology-Toxicology
    Full Title: Infusion of a single dose of erythropoietin to Prevent Injury in an Ischemia Reperfusion forearm model - A randomised cross-over study to evaluate if infusion of a single dose of EPO protects again...
    Medical condition: Myocardial ischemia-reperfusion injury.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059512 Apoptosis LLT
    9.1 10028601 Myocardial ischemia LLT
    9.1 10051624 Myocardial reperfusion injury LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-006266-29 Sponsor Protocol Number: 2504/2008 Start Date*: 2008-11-20
    Sponsor Name:AZIENDA OSPEDALIERA PISANA
    Full Title: Optimal Strategy for Coronary Artery Reperfusion
    Medical condition: Acute coronary syndrome ST-elevation patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051592 Acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-001321-17 Sponsor Protocol Number: 11275 Start Date*: 2016-12-02
    Sponsor Name:University of Oxford
    Full Title: A randomised control trial of 5-Aminolevulinic Acid in combination with Sodium Ferrous Citrate to Enhance Cardioprotection in Adults undergoing Cardiac Surgery
    Medical condition: Low cardiac output states following cardioplegic arrest for cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004863 10007602 Cardiac and vascular procedural complications HLT
    19.0 10007541 - Cardiac disorders 10051624 Myocardial reperfusion injury PT
    19.0 10042613 - Surgical and medical procedures 10066123 Cardiopulmonary bypass PT
    19.0 10007541 - Cardiac disorders 10024920 Low output state LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2017-002784-18 Sponsor Protocol Number: 13005 Start Date*: 2018-07-24
    Sponsor Name:Clinical Trials and Research Governance
    Full Title: Safety and efficacy of Tofacitinib in ameliorating ischaemia reperfusion injury and allograft pancreatitis in solid organ transplantation – a pilot study
    Medical condition: Ischaemia reperfusion injury and allograft pancreatitis.
    Disease: Version SOC Term Classification Code Term Level
    20.1 10017947 - Gastrointestinal disorders 10066127 Ischaemic pancreatitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-004198-10 Sponsor Protocol Number: SCT-Cpx-003 Start Date*: 2012-03-22
    Sponsor Name:Swiss Cardio Technologies AG
    Full Title: A Single-Centre, Single Blind, Randomized, Active-Controlled Phase III Non-Inferiority Study to Investigate the Safety and Efficacy of the Cardioplegic Solution Cardioplexol when used during a Ca...
    Medical condition: Medical conditions necessitating an elective surgical coronary artery bypass grafting (CABG) and/or a valve repair/replacement.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2009-016954-42 Sponsor Protocol Number: SCT-Cpx-001 Start Date*: 2010-10-28
    Sponsor Name:Swiss Cardio Technologies AG
    Full Title: Randomized Clinical Safety and Efficacy Investigation of the Swiss Cardio Technologies Cardioplexol Solution in comparison with Buckberg Solution
    Medical condition: Medical conditions necessitating an elective surgical coronary artery bypass grafting (CABG) and/or a valve repair/replacement.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004878-28 Sponsor Protocol Number: dipy001 Start Date*: 2006-12-27
    Sponsor Name:UMCN farm-tox
    Full Title: Does caffeine reduce dipyridamole-induced protection against ischemia-reperfusion injury?
    Medical condition: Reperfusion after an ischemic accident will limit tissue damage (infacrt size), though on the other hand reperfusion injury will also cause tissue damage by the release of ROS and facilitating cell...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10062828 Ischemic heart disease prophylaxis LLT
    Population Age: Adults Gender: Male
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2004-004983-56 Sponsor Protocol Number: 3010410 Start Date*: 2005-02-28
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust [...]
    1. Hull and East Yorkshire Hospitals NHS Trust
    2. University of Hull
    Full Title: A randomised placebo controlled trial of pre-operative statin use in elective abdominal aortic aneurysm repair to determine the effect on systemic and cellular responses of ischaemia reperfusion in...
    Medical condition: Ischaemia reperfusion injury following elective abdominal aortic aneurysm repair. This occurs when muscle or organ is subjected to an ischaemic insult with associated damage followed by reperfusio...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2020-000123-39 Sponsor Protocol Number: VITACTOH Start Date*: 2020-04-02
    Sponsor Name:Fundación Investigación Biomédica Hospital Ramón y Cajal
    Full Title: Phase II clinical trial, randomized, double blind, masked, controlled with physiological serum about the efficacy of intravenous administration of vitamin C during the anhepatic phase of liver tran...
    Medical condition: Reperfusion syndrome
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-004464-57 Sponsor Protocol Number: SWIFT-DIRECT Start Date*: 2019-04-17
    Sponsor Name:Universtiy Hospital Bern
    Full Title: Solitaire™ With the Intention For Thrombectomy Plus Intravenous t-PA Versus DIRECT Solitaire™ Stent-retriever Thrombectomy in Acute Anterior Circulation Stroke
    Medical condition: Acute Anterior Circulation Stroke
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Ongoing) AT (Completed) GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
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