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Clinical trials for Secretion

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    398 result(s) found for: Secretion. Displaying page 1 of 20.
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    EudraCT Number: 2004-005239-25 Sponsor Protocol Number: CPR-SFY5904-EN-E01 Start Date*: 2005-07-06
    Sponsor Name:Sanofi-Synthelabo Research
    Full Title: An open-label, multicenter study evaluating the long-term safety and efficacy of SR121463B in patients with Syndrome of Inappropriate Antidiuretic Hormone Secretion.
    Medical condition: Syndrome of Inappropriate Antidiuretic Hormone (SIADH) with serum sodium between 115 and 132 mmol/L.
    Disease: Version SOC Term Classification Code Term Level
    7.1 10040626 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-003800-38 Sponsor Protocol Number: SAFA-1-2014 Start Date*: 2014-02-24
    Sponsor Name:Department of Medical Research
    Full Title: The effects of tolvaptan on renal handling of water and sodium, vasoactive hormones and circulatory system, during basal conditions and during inhibition of the nitric oxide system in healthy subj...
    Medical condition: Hyponatremia SIADH (Syndrome of Inappropriate Antidiuretic Hormone secretion)
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004861 10021038 Hyponatremia LLT
    14.1 100000004860 10040626 SIADH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-001169-33 Sponsor Protocol Number: SAFA-1-2012 Start Date*: 2012-07-02
    Sponsor Name:Department of Medical Research
    Full Title: Effects of tolvaptan on renal sodium and water handling and circulation during inhibition of the nitric oxide system in healthy subjects
    Medical condition: SIADH (Syndrome of inappropriate ADH production) Overhydration Hyponatrimia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10021038 Hyponatremia LLT
    14.1 10014698 - Endocrine disorders 10040626 SIADH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-001973-15 Sponsor Protocol Number: SAFA-2-2014 Start Date*: 2014-11-18
    Sponsor Name:University Clinic in Nephrology and Hypertension, Department of Medical Research
    Full Title: Renal Handling of Water and Sodium in Autosomal Dominant Polycystic Kidney Disease. The effects of tolvaptan on renal handling of water and sodium , vasoactive hormones and central hemodynamics dur...
    Medical condition: Hyponatreamia SIADH ( Syndrome of Inappropriate Antidiuretic Hormone Secretion) Overhydration Autosomal dominant polycystic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004861 10021038 Hyponatremia LLT
    17.0 100000004860 10040626 SIADH LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-000161-40 Sponsor Protocol Number: AdrenalClock Start Date*: 2022-07-18
    Sponsor Name:Medical University of Vienna, Division of Endocrinology
    Full Title: Investigating cardiometabolic risk factors and changes in chronobiology patterns in patients with autonomous adrenal cortisol secretion
    Medical condition: Autonomous cortisol secretion in patients with adrenal adenoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-004764-31 Sponsor Protocol Number: 02-2006 Start Date*: 2007-01-11
    Sponsor Name:Max Planck Institute of Psychiatry
    Full Title: Effects of corticotropin-releasing hormone on sleep electroencephalogram and sleep associated hormone secretion in young healthy women
    Medical condition: Healthy volunteers. The aim is to test the effects of CRH on sleep electroencephalogram and sleep associated secretion of growth hormone and cortisol
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004115-27 Sponsor Protocol Number: IIBSP-OXI-2020-102 Start Date*: 2021-05-10
    Sponsor Name:Institut de Recerca Hospital de la Santa Creu i Sant Pau - IIB Sant Pau
    Full Title: Identification and clinical relevance of oxytocin deficient status: randomized, crossover, placebo-controlled pathophysiological pilot study: GLP1 study
    Medical condition: Hypopituitarism
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019660-36 Sponsor Protocol Number: Anakinra1 Start Date*: 2010-12-07
    Sponsor Name:UMC St Radboud
    Full Title: The effect of interleukin-1 receptor antagonist on insulin secretion
    Medical condition: Beta-cell dysfunction
    Disease: Version SOC Term Classification Code Term Level
    12.1 10052341 Impaired insulin secretion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-021403-24 Sponsor Protocol Number: 001 Start Date*: 2010-11-10
    Sponsor Name:North Lincolnshire and Goole NHS Foundation Trust
    Full Title: A Prospective Pilot Study to Investigate the Effectiveness of Quinagolide in the Improvement of Psychological Symptoms Associated with Hyperprolactinaemia.
    Medical condition: Hyperprolactinaemia
    Disease: Version SOC Term Classification Code Term Level
    12.1 10020737 Hyperprolactinaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-011228-73 Sponsor Protocol Number: OCTUMI-03 Start Date*: 2010-02-09
    Sponsor Name:University of Oxford [...]
    1. University of Oxford
    2.
    Full Title: A pilot study of Aripiprazole treatment for antipsychotic induced hyperprolactinaemia in young patients with severe mental illness and learning disabilities.
    Medical condition: Antipsychotic induced hyperprolactinaemia
    Disease: Version SOC Term Classification Code Term Level
    12 10020737 Hyperprolactinaemia LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-005579-38 Sponsor Protocol Number: 1 Start Date*: 2022-01-31
    Sponsor Name:Aarhus University Hospital, Department of Endocrinology
    Full Title: Cabergoline as a Preventive Treatment for Chronic Migraine: an Investigator-Initiated, Randomized Clinical Trial
    Medical condition: Migraine
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004860 10020739 Hyperprolactinemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-006514-42 Sponsor Protocol Number: A-99-52030-216 Start Date*: 2008-01-23
    Sponsor Name:Institut Produits Synthèse (IPSEN) AB
    Full Title: A PHASE IV, OPEN-LABEL, RANDOMISED, CROSS-OVER STUDY TO ASSESS PATIENT PREFERENCE AND HEALTH ECONOMY IN PATIENTS WITH NEUROENDOCRINE TUMOURS, TREATED WITH LANREOTIDE AUTOGEL GIVEN AS SELF ADMINISTR...
    Medical condition: Symptoms associated with carcinoid syndrome in patients with neuroendocrine tumours
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007270 Carcinoid syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2013-002596-18 Sponsor Protocol Number: LX1606.1-302-CS Start Date*: 2013-12-17
    Sponsor Name:Lexicon Pharmaceuticals, Inc.
    Full Title: A Multicenter, Long-term Extension Study to Further Evaluate the Safety and Tolerability of Telotristat Etiprate (LX1606)
    Medical condition: Carcinoid Syndrome
    Disease: Version SOC Term Classification Code Term Level
    19.1 10014698 - Endocrine disorders 10007270 Carcinoid syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) ES (Completed) SE (Completed) IT (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004654-81 Sponsor Protocol Number: DL06001/02 Start Date*: 2007-12-20
    Sponsor Name:Summit (Cambridge) Ltd.
    Full Title: A phase IIa study to evaluate the relative efficacy and safety/tolerability of a single agent vs. a combination treatment for reducing saliva secretion in Parkinson’s disease patients
    Medical condition: Sialorrhoea associated with Parkinson's Disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059812 Sialorrhoea LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-013222-16 Sponsor Protocol Number: 8-55-52060-004 Start Date*: 2009-12-02
    Sponsor Name:Ipsen Pharma
    Full Title: Phase II, open, adaptive, dose escalating, multicentre titration study to assess the efficacy and safety of repeated subcutaneous administration of different doses of BIM 23A760 in patients with ca...
    Medical condition: carcinoid syndrome
    Disease: Version SOC Term Classification Code Term Level
    12.0 10007270 Carcinoid syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) NL (Prematurely Ended) LV (Prematurely Ended) CZ (Prematurely Ended) FI (Prematurely Ended) IE (Completed) ES (Prematurely Ended) BE (Completed) AT (Prematurely Ended) FR (Completed) DE (Prematurely Ended) IT (Prematurely Ended) SK (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2021-003794-56 Sponsor Protocol Number: 35RC21_8901_CRYSTAL Start Date*: 2022-03-23
    Sponsor Name:RENNES University Hospital
    Full Title: COMPARISON OF TOPICAL HYDROCORTISONE VERSUS DEXAMETHASONE TREATMENT FOR INFLAMMATORY SECRETIONS OF THE CONJUNCTIVA IN PATIENTS WITH OCULAR PROSTHESIS
    Medical condition: Conjunctival, Conjunctival inflammation, Corticosteroids, Inflammation, Prosthesis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-002950-32 Sponsor Protocol Number: 1502 Start Date*: 2006-11-23
    Sponsor Name:Gentofte University Hospital
    Full Title: Long term effects of DPP-IV inhibitor treatment on the secretion and action of the incretin hormones in patients with type 2 diabetes
    Medical condition: Type 2 diabetes diagnosed according to the criteria from WHO
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003014-22 Sponsor Protocol Number: Thalamus_V3 Start Date*: 2018-06-25
    Sponsor Name:Medical University of Vienna
    Full Title: The role of leptin in regulating hepatic lipid metabolism in humans
    Medical condition: lipodystrophy patients, patients after liver transplantation and healthy controls
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004488-31 Sponsor Protocol Number: S-02005 Start Date*: Information not available in EudraCT
    Sponsor Name:Rikshospitalet University Hospital, University of Oslo
    Full Title: Does cyclosporine A reduce the insulin secretion from the pancreas?
    Medical condition: Kidney failure / dialysis patients / transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001315-22 Sponsor Protocol Number: GH003 Start Date*: 2006-03-09
    Sponsor Name:Ludwig Boltzmann Gesellschaft
    Full Title: The effect of the cholinesterase inhibitor donepezil on organic and functional deficits related to growth hormone deficiency in old age.
    Medical condition: We plan to study healthy aging subjects.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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