Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Serotonin

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43875   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    126 result(s) found for: Serotonin. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2009-016716-20 Sponsor Protocol Number: 08/152/WRI Start Date*: 2010-03-03
    Sponsor Name:Brighton and Sussex University Hospitals NHS Trust
    Full Title: Better targeting of antidepressants in older people: the influence of age and genetic background on serotonin signalling
    Medical condition: Depression
    Disease: Version SOC Term Classification Code Term Level
    12.0 10021036 Hyponatraemia LLT
    12.0 10017955 Gastrointestinal haemorrhage LLT
    12.0 10040108 Serotonin syndrome LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-004156-39 Sponsor Protocol Number: no sponsor Start Date*: 2005-11-18
    Sponsor Name:Dept. of Neurology Vienna
    Full Title: Brain serotonin 5-HT1A receptor binding in human mesial temporal lobe epilepsy measured by positron emission tomography and [11C]WAY-100635
    Medical condition: Application of [11C]WAY-100635, a brain serotonin 5-HT1A receptor ligand, in patients with mesial temporal lobe epilepsy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000106-31 Sponsor Protocol Number: 2958 Start Date*: 2005-03-15
    Sponsor Name:Royal Liverpool University Hospital Clinical Trials 4th floor Linda McCartney Centre
    Full Title: IMPACT OF CYP2D6, SEROTONIN TRANSPORTER, 5HT1, 5HT2 AND 5HT3 RECEPTOR AND MU RECEPTOR GENE POLYMORPHISMS ON EFFICACY AND TOXICITY OF TRAMADOL
    Medical condition: OSTEOPOROSIS
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-003280-38 Sponsor Protocol Number: PSY-NIL-0006 Start Date*: 2016-05-04
    Sponsor Name:Medical University of Vienna
    Full Title: Positron Emission Tomography assessment of Ketamine Binding of the Serotonin Transporter and its Relevance for Rapid Antidepressant Response
    Medical condition: 20 patients with severe unipolar depression (structured clinical interview for DSM-IV and the 17-item Hamilton Depression Rating Scale), also 20 age and sex matched healthy controls. plus 12 HC f...
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10045543 Unipolar depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2004-004004-20 Sponsor Protocol Number: UI04/6748 Start Date*: 2005-09-26
    Sponsor Name:University of Leeds
    Full Title: A Randomised, Double-blind, Placebo Controlled trial to test the efficacy of St John's Wort (Hypericum Perforatum) for Premenstrual Syndrome.
    Medical condition: The 'premenstrual syndrome' is a cyclical condition occurring 7-10 days before the onset of menstruation, and is relieved at, or shortly after commencement of menstrual flow. The most commonly repo...
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-001217-25 Sponsor Protocol Number: 2016-001217-25 Start Date*: 2016-09-07
    Sponsor Name:Uppsala University
    Full Title: Emotion, Serotonin and Premenstrual Dysphoric Disorder (EmSeP)
    Medical condition: Premenstrual Dysphoric Disorder
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-006576-38 Sponsor Protocol Number: 11821 Start Date*: 2007-09-04
    Sponsor Name:Siegfried KASPER, O.Univ.Prof.Dr.Dr.h.c., Medizinische Universität Wien
    Full Title: Longitudinal imaging of serotonin transporter occupancy using PET and [11C]DASB in patients with major depression treated with escitalopram or citalopram
    Medical condition: Major depression
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002992-33 Sponsor Protocol Number: 54135419TRD3013 Start Date*: 2020-08-04
    Sponsor Name:Janssen-Cilag International NV
    Full Title: A Randomized, Open-label, Rater-Blinded, Active-Controlled, International, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Flexibly Dosed Esketamine Nasal Spray Compared Wit...
    Medical condition: Treatment-Resistant Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004873 10081270 Major depressive disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) CZ (Completed) PL (Completed) DE (Completed) HU (Completed) FR (Completed) BE (Completed) PT (Completed) BG (Completed) DK (Completed) AT (Completed) NO (Completed) FI (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2015-000502-19 Sponsor Protocol Number: PSY-NIL-0002 Start Date*: 2016-06-21
    Sponsor Name:Medical University of Vienna, Department of Psychiatry and Psychotherapy
    Full Title: Effects of sex steroid hormones on serotonin synthesis and degradation measured with PET
    Medical condition: Gender Dysphoria (Female-to-male transsexuals and male-to-female transsexuals)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-002232-82 Sponsor Protocol Number: KIH18001 Start Date*: 2019-07-25
    Sponsor Name:Karolinska Institutet
    Full Title: Downstream targets of SSRI effect in treatment of Major Depressive Disorder
    Medical condition: Major depressive disorder (MDD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000309-60 Sponsor Protocol Number: 120101 Start Date*: 2016-03-30
    Sponsor Name:Göteborgs universitet
    Full Title: Biochemical and neuropsychological effects on Premenstrual Dysphoric Disorder after acute administration of escitalopram
    Medical condition: Premenstrual Dysphoric Disorder
    Disease: Version SOC Term Classification Code Term Level
    18.1 10038604 - Reproductive system and breast disorders 10051537 Premenstrual dysphoric disorder PT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019423-61 Sponsor Protocol Number: GENRAS Start Date*: 2010-10-28
    Sponsor Name:Medizinische Universität Wien,Univ.Klinik f.Psychiatrie und Psychotherapie
    Full Title: GENRAS (GENetics of Response to Agomelatine vs. EScitalopram)
    Medical condition: depressive disorder
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2022-001989-36 Sponsor Protocol Number: SIGN Start Date*: 2022-09-07
    Sponsor Name:Med. Univ. Wien, Klinik f. Innere Med I, Onkologie
    Full Title: Selective serotonin reuptake inhibition in patients with advanced gastroesophageal cancer receiving immunochemotherapy: a prospective phase II trial
    Medical condition: gastroesophageal cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005772-35 Sponsor Protocol Number: LINEZOLID01 Start Date*: 2021-04-21
    Sponsor Name:UCLouvain
    Full Title: Study on linezolid use and adverse drug reactions in clinical practice: Follow-up of patients treated in Belgian Hospitals
    Medical condition: All infections treated with the antibiotic linezolid
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-013222-16 Sponsor Protocol Number: 8-55-52060-004 Start Date*: 2009-12-02
    Sponsor Name:Ipsen Pharma
    Full Title: Phase II, open, adaptive, dose escalating, multicentre titration study to assess the efficacy and safety of repeated subcutaneous administration of different doses of BIM 23A760 in patients with ca...
    Medical condition: carcinoid syndrome
    Disease: Version SOC Term Classification Code Term Level
    12.0 10007270 Carcinoid syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) NL (Prematurely Ended) LV (Prematurely Ended) CZ (Prematurely Ended) FI (Prematurely Ended) IE (Completed) ES (Prematurely Ended) BE (Completed) AT (Prematurely Ended) FR (Completed) DE (Prematurely Ended) IT (Prematurely Ended) SK (Prematurely Ended) GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023996-25 Sponsor Protocol Number: 26081985 Start Date*: 2010-12-21
    Sponsor Name:
    Full Title: The effect of fluoxetine and 5-HT4 serotonin receptor agonists on cerebral axonal energy metabolism and glutamate levels in multiple sclerosis.
    Medical condition: Multiple sclerosis (both relapsing remitting and progressive forms)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004029-87 Sponsor Protocol Number: KCL/PCT-CT2004-1 Start Date*: 2005-01-24
    Sponsor Name:Institute of Psychiatry
    Full Title: Pillot randomised controlled trial of antidepressant switching for treatmetn-refractory depression in primary care
    Medical condition: Depression
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000216-24 Sponsor Protocol Number: 2006-Traz_insomnia Start Date*: 2006-04-21
    Sponsor Name:University of Bristol
    Full Title: Serotonin sensitivity in insomnia: a placebo-controlled crossover study of sleep after 5HT2 blockade in primary insomnia.
    Medical condition: Primary insomnia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2019-000737-39 Sponsor Protocol Number: AD04-301 Start Date*: 2020-04-28
    Sponsor Name:Adial Pharmaceuticals Inc.
    Full Title: A 24-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Tolerability of AD04 (Ondansetron) in Adults with A...
    Medical condition: Adult patients diagnosed with moderate or severe alcohol use disorder
    Disease: Version SOC Term Classification Code Term Level
    20.1 10037175 - Psychiatric disorders 10080021 Alcohol use disorder PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) BG (Completed) PL (Completed) EE (Completed) LV (Completed) HR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-000846-32 Sponsor Protocol Number: SELEIS Start Date*: 2014-11-06
    Sponsor Name:Fundació Privada Hospital Asil de Granollers
    Full Title: EFFECT OF SEROTONIN AND LEVODOPA FUNCTIONAL RECOVERY IN PATIENTS WITH CEREBRAL INFARCTION
    Medical condition: Functional recovery in patients with cerebral infarction
    Disease: Version SOC Term Classification Code Term Level
    17.0 10029205 - Nervous system disorders 10008118 Cerebral infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  4  5  6  7  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Fri May 17 12:16:39 CEST 2024 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA