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Clinical trials for Sign test

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    3,789 result(s) found for: Sign test. Displaying page 1 of 190.
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    EudraCT Number: 2005-003162-42 Sponsor Protocol Number: M/37779/21 Start Date*: 2005-10-21
    Sponsor Name:Almirall Prodesfarma S.A.
    Full Title: A double-blind, randomized, parallel, multicenter, vehicle-controlled, left/right paired comparison to study the efficacy, safety and tolerability of 1% LAS 37779 cream administered once and twice ...
    Medical condition: patients with mild to moderate chronic plaque psoriasis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002367-24 Sponsor Protocol Number: PC TA001/04 Start Date*: 2004-10-20
    Sponsor Name:PhotoCure ASA
    Full Title: A blinded, prospective, randomised, placebo-controlled, multi-centre, split-face study of photodynamic therapy with Metvix 160 mg/g cream in subjects with acne vulgaris.
    Medical condition: Moderate inflammatory acne vulgaris.
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003311-32 Sponsor Protocol Number: F 0106 Start Date*: 2008-02-01
    Sponsor Name:FORIM GmbH
    Full Title: Comparative surveillance study to assess the effect of lipid based nutrition vs. standard regimen on clinical outcome in ventilated patients.
    Medical condition: The aim of the presented surveillance is to confirm the results of the pilot study showing a significant reduction in respirator days and ICU-stay in patients with lipid based nutrition compared to...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-016261-28 Sponsor Protocol Number: H 521 000 - 0915 Start Date*: 2010-01-26
    Sponsor Name:Almirall Hermal GmbH
    Full Title: Randomized, observer-blind, multi-center, reference-controlled phase IIb study to evaluate the efficacy of topically applied LAS41002 lotion in the treatment of scalp psoriasis
    Medical condition: Psoriasis vulgaris on the scalp
    Disease: Version SOC Term Classification Code Term Level
    12.0 10037157 Psoriasis of scalp LLT
    12.0 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-000871-16 Sponsor Protocol Number: JBJ-2005-01 Start Date*: 2006-03-07
    Sponsor Name:Dr John Berth-Jones
    Full Title: Methotrexate in adults with severe atopic dermatitis: a double-blind, randomised, parallel-group, placebo-controlled trial
    Medical condition: Severe atopic dermatitis in adults
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2019-000612-29 Sponsor Protocol Number: IM011075 Start Date*: 2019-11-21
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: An Open-Label, Multi-Center Extension Study to Characterize the Long-Term Safety and Efficacy of BMS-986165 in Subjects with Moderate-to-Severe Plaque Psoriasis
    Medical condition: Moderate-to-Severe Plaque Psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Trial now transitioned) PL (Trial now transitioned) GB (GB - no longer in EU/EEA) CZ (Trial now transitioned) SE (Trial now transitioned) ES (Ongoing) DE (Ongoing) FI (Trial now transitioned) FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-013707-63 Sponsor Protocol Number: 1 Start Date*: 2010-03-05
    Sponsor Name:C.U.B ERASME HOSPITAL
    Full Title: POSTOPERATIVE ANALGESIA USING PREPERITONEAL CONTINUOUS INFUSIONS OF ROPIVACAINE IN PATIENTS UNDERGOING LIVER SURGERY -CONSEQUENCES ON ROPIVACAINE METABOLISM
    Medical condition: PATIENTS WITH HEPATIC TUMORS BUT WITH A GOOD HEPATIC FUNCTION BEFORE SURGERY
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000435-99 Sponsor Protocol Number: 03/06/OXD/TP3 Start Date*: 2006-06-07
    Sponsor Name:Zentiva a.s.
    Full Title: A Randomized, Double Blind, Placebo Controlled Multicenter Study to Assess the Efficacy and Safety of nasal spray ANTIRIN® and NASIC® in the Treatment of Allergic Rhinitis.
    Medical condition: Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039083 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2013-001262-42 Sponsor Protocol Number: NTA1201 Start Date*: 2013-12-10
    Sponsor Name:National Stroke Research Institute
    Full Title: STOP-AUST: The Spot sign and Tranexamic acid On Preventing ICH growth – AUStralasia Trial
    Medical condition: Intracerebral Haemorrhage
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10019551 Hemorrhage intracerebral LLT
    14.1 100000004852 10022751 Intracerebral bleed LLT
    14.1 100000004852 10055815 Haemorrhage intracerebral LLT
    14.1 100000004852 10068342 Intracerebral haematoma LLT
    14.1 100000004852 10022754 Intracerebral hemorrhage LLT
    14.1 100000004852 10022753 Intracerebral haemorrhage LLT
    14.1 100000004852 10068344 Intracerebral hematoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2004-002350-63 Sponsor Protocol Number: SL300/2004/002/D Start Date*: 2004-11-19
    Sponsor Name:Stallergenes GmbH & Co.KG
    Full Title: Efficacy and Safety of Sublingual Immunotherapy with Ultra-Rush Titration in Children with Allergic Rhinoconjunctivitis to Tree Pollen, a Multicentre DBPC Trial
    Medical condition: Allergic rhinitis against birch pollen
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005876-33 Sponsor Protocol Number: 13/05/OXD/TP3 Start Date*: 2006-05-10
    Sponsor Name:Zentiva a.s.
    Full Title: A Randomised, Double Blind, Placebo Controlled, Multicenter Study to Assess the Efficacy and Safety of nasal spray ANTIRIN® and NASIC® in the Treatment of Acute Viral Rhinitis
    Medical condition: Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039083 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2020-005547-23 Sponsor Protocol Number: 12217 Start Date*: 2021-07-22
    Sponsor Name:AZ Delta vzw
    Full Title: Management of Popeye sign with botulinum toxin after tenotomy of the long head of the biceps tendon: a double-blinded randomized controlled trial
    Medical condition: Popeye sign or cramping pain after shoulder artroscopy with biceps tenotomy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005461-19 Sponsor Protocol Number: 11/06/OXD/TP3 Start Date*: 2006-12-20
    Sponsor Name:Zentiva a.s.
    Full Title: A Randomized, Double Blind, Placebo Controlled Multicenter Study to Assess the Tolerability and Safety of ANTIRIN® nasal spray and drops in two Age Groups of Children with Acute Rhinitis
    Medical condition: Rinitis acuta
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039083 Rhinitis LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-002098-40 Sponsor Protocol Number: LP0133-1182 Start Date*: 2016-02-10
    Sponsor Name:LEO Pharma A/S
    Full Title: A Phase 2a, Proof of Concept Trial, testing twice daily application of LEO 124249 ointment 30mg/g in the treatment of mild to moderate inverse psoriasis
    Medical condition: inverse psoriasis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004858 10063160 Inverse psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-004350-82 Sponsor Protocol Number: OV-1004 Start Date*: 2008-03-17
    Sponsor Name:Lundbeck Inc
    Full Title: Safety and Effectiveness of Open-Label Clobazam in Subjects with Lennox Gastaut Syndrome
    Medical condition: Lennox-Gastaut syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048816 Lennox-Gastaut syndrome LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: LT (Completed) BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002477-31 Sponsor Protocol Number: AB0602/1 Start Date*: 2007-05-23
    Sponsor Name:Artu Biologicals Europe B.V.
    Full Title: A randomised, double-blind, placebo-controlled, multi-centre, multi-national Phase II / III follow-up study to assess long-term efficacy and safety of three different dose regimens of Oralgen® Gras...
    Medical condition: Allergic rhinoconjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001728 Allergic rhinoconjunctivitis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed) LT (Completed) HU (Completed) DE (Completed) CZ (Completed) SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-002660-41 Sponsor Protocol Number: NVG14L127 Start Date*: 2019-04-29
    Sponsor Name:SANTEN SAS
    Full Title: A Phase IIIb, prospective, interventional, multicentre, three-year study to explore the long-term evolution of sign and symptoms, and occurrence of complications in Dry Eye Disease patients with se...
    Medical condition: DRY EYE DISEASE WITH SEVERE KERATITIS
    Disease: Version SOC Term Classification Code Term Level
    20.0 10015919 - Eye disorders 10023332 Keratitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004278-28 Sponsor Protocol Number: RD.03.SPR.29058 Start Date*: 2007-02-26
    Sponsor Name:GALDERMA Research & Development
    Full Title: Efficacy and Safety of a Fixed Combination Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel Compared to Clindamycin 1% / Benzoyl Peroxide 5% Gel in the Treatment of Acne Vulgaris
    Medical condition: Treatment of acne vulgaris
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) DE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2019-002533-11 Sponsor Protocol Number: AC-055-315 Start Date*: 2020-06-17
    Sponsor Name:ACTELION Pharmacteuticals Ltd.
    Full Title: A Phase 3, Prospective, Multicenter, Double-blind, Double-dummy, Randomized, Active-controlled, Parallel-group, Group-sequential, Adaptive, Event-driven Study to Compare Efficacy, Safety, and Toler...
    Medical condition: Pulmonary arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10064911 Pulmonary arterial hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) CZ (Trial now transitioned) HU (Trial now transitioned) SE (Trial now transitioned) FR (Trial now transitioned) GB (GB - no longer in EU/EEA) DK (Trial now transitioned) NL (Trial now transitioned) PL (Trial now transitioned) PT (Trial now transitioned) BE (Trial now transitioned) NO (Completed) SK (Trial now transitioned) AT (Trial now transitioned) IT (Trial now transitioned) BG (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-000986-17 Sponsor Protocol Number: ALZ-801-201ADBM Start Date*: 2020-09-11
    Sponsor Name:Alzheon Inc.
    Full Title: A Phase 2, Single Arm, Study of the Biomarker Effects of ALZ-801 in Subjects with Early Alzheimer’s Disease Who Are Carriers of the ε4 Variant of the Apolipoprotein E Gene (APOE4/4 or APOE3/4)
    Medical condition: Subjects with a clinical diagnosis of Alzheimer's disease who are APOE 4 carriers (APOE4/4, APOE3/4) and at the Early stage of disease, ages 50-80 years
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Trial now transitioned) NL (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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