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Clinical trials for Smoking Tobacco

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    122 result(s) found for: Smoking Tobacco. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2022-002492-11 Sponsor Protocol Number: PRECESTO Start Date*: 2023-09-13
    Sponsor Name:NFL BIOSCIENCES SA
    Full Title: Phase II Study Assessing Efficacy and Safety of NFL-101 on Reduction of Reinforcing Properties of Cigarettes
    Medical condition: Tobacco addiction
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004869 10043905 Tobacco use HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-007020-18 Sponsor Protocol Number: 1999/07 Start Date*: 2008-05-26
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Efficacy of baclofen in the treatment of nicotine addicted patients:randomized, double blind study of Baclofen versus placebo
    Medical condition: Smoking addiction
    Disease: Version SOC Term Classification Code Term Level
    12.0 10043903 Tobacco abuse LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000546-31 Sponsor Protocol Number: A3051104 Start Date*: 2008-07-16
    Sponsor Name:Pfizer Ltd, Ramsgate Road,Sandwich,Kent CT13 9NJ
    Full Title: A RANDOMIZED, MULTICENTRE, DOUBLE BLIND, PLACEBO CONTROLLED STUDY EVALUATING THE EFFICACY OF VARENICLINE IN CESSATION OF ORAL TOBACCO USE
    Medical condition: Cessation of oral smokeless tobacco use in current non-smokers.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10053325 Smoking cessation therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2019-003720-20 Sponsor Protocol Number: WI231434 Start Date*: 2019-10-16
    Sponsor Name:University of Zagreb School of Medicine
    Full Title: Varenicline Versus Cytisine for Smoking Cessation in the Primary Care Setting in Croatia and Slovenia - a Randomized Controlled Trial
    Medical condition: Tobacco addiction
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004978-42 Sponsor Protocol Number: ADDICTSTATINE Start Date*: 2015-02-25
    Sponsor Name:CHU DE POITIERS
    Full Title: Pilot randomized double blind, placebo controlled trial of the efficacy of simvastatin for smoking cessation
    Medical condition: Smoking cessation
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004869 10008374 Cessation of smoking LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003250-29 Sponsor Protocol Number: IPAB-07-002 Start Date*: 2008-03-14
    Sponsor Name:Independent Pharmaceutica AB
    Full Title: A randomised, placebo-controlled, multi-centre study on the efficacy of Niccine, a vaccine for nicotine, in smoking relapse prevention, assessed in abstinent, adult smokers.
    Medical condition: The intended indication for the drug under investigation is smoking relapse prevention. Tobacco smoking has been identified as the single largest preventable cause of morbidity and premature death ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056478 Nicotine addiction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003588-37 Sponsor Protocol Number: P150952J Start Date*: 2018-05-09
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: A randomized, placebo controlled, double blind, double dummy, multicenter trial comparing electronic cigarettes with nicotine to varenicline and to electronic cigarettes without nicotine
    Medical condition: Smokers smoking at least 10 cigarettes/day in the past year
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10053325 Smoking cessation therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-004461-34 Sponsor Protocol Number: 1.0 Start Date*: 2006-11-02
    Sponsor Name:University of Nottingham
    Full Title: Open label randomised trial of nicotine replacement therapy and oral smokeless tobacco (snus) in smoking cessation
    Medical condition: Smoking cessation
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10053325 Smoking cessation therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-001764-21 Sponsor Protocol Number: MANS11 Start Date*: 2011-05-19
    Sponsor Name:Magle AB
    Full Title: The effect of 6 weeks’ use of the Nicachet 4 mg nicotine powder in pouch on the oral mucosa. A short-term smoking cessation and tolerability study.
    Medical condition: Nicotine addiction
    Disease: Version SOC Term Classification Code Term Level
    13.1 10042613 - Surgical and medical procedures 10053325 Smoking cessation therapy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004626-10 Sponsor Protocol Number: 10003 Start Date*: 2006-03-16
    Sponsor Name:Pulmonary Department, Gentofte Hospital
    Full Title: Smoking cessation by nurses with smokelesstobacco buccal tabltes, nicotine buccal tablets, nicotine patches with repeated thearapy every 6 months for 2 years
    Medical condition: Smopking (nicotine addiction/Tobacco addiction)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006845-13 Sponsor Protocol Number: A6431111 Start Date*: 2009-02-02
    Sponsor Name:McNeil AB (Johnson & Johnson Consumer and Personal Products Worldwide, J&J CPPW)
    Full Title: Efficacy and safety following use of a novel nicotine replacement therapy. A multicenter, randomized, double blind, placebo-controlled, parallel group, 52-week study in smokers motivated to quit.
    Medical condition: For the treatment of tobacco dependence by relieving nicotine craving and withdrawal symptoms, thereby facilitating smoking cessation in smokers motivated to quit abruptly.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008374 Cessation of smoking LLT
    9.1 10053325 Smoking cessation therapy LLT
    9.1 10059612 Tobacco withdrawal symptoms LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004720-24 Sponsor Protocol Number: qmul120508 Start Date*: 2009-03-27
    Sponsor Name:Queen Mary and Westfield College, University of London
    Full Title: Effects of an extended period of varenicline use prior to quitting smoking on post-quitting urges to smoke
    Medical condition: Tobacco Dependence (Smoking Cessation)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008374 Cessation of smoking LLT
    9.1 10053325 Smoking cessation therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-002731-28 Sponsor Protocol Number: P12-01/BP1.4979 Start Date*: 2013-03-01
    Sponsor Name:Bioprojet
    Full Title: Randomized placebo controlled trial assessing the efficacy and safety of BP1.4979 in smoking cessation
    Medical condition: Smoking cessation
    Disease: Version SOC Term Classification Code Term Level
    16.1 100000004869 10008374 Cessation of smoking LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2007-002203-40 Sponsor Protocol Number: 07.0056 Start Date*: 2007-10-03
    Sponsor Name:St. George's, University of London
    Full Title: Effect of hydrocortisone on desire to smoke and tobacco withdrawal symptoms
    Medical condition: Nicotine addiction; specifically, cortisol deficiency following smoking cessation.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056478 Nicotine addiction LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022334-92 Sponsor Protocol Number: qmul250510 Start Date*: 2011-01-07
    Sponsor Name:Barts and the London School of Medicine and Dentistry, Queen Mary University of London
    Full Title: Effects of a combination of varenicline and transdermal nicotine patch on post-quitting urges to smoke
    Medical condition: Tobacco dependence (smoking cessation)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005334-21 Sponsor Protocol Number: DRI6938 Start Date*: 2007-03-21
    Sponsor Name:sanofi-aventis recherche et developpement
    Full Title: A randomized, double-blind, placebo-controlled, parallel group, fixed-dose, 8-week treatment, multi-center trial evaluating the dose effect relationship for efficacy and the safety of 3 oral doses ...
    Medical condition: Aid to smoking cessation in cigarette smokers
    Disease: Version SOC Term Classification Code Term Level
    8.1 10057852 Nicotine dependence LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) BE (Completed) FR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-022335-11 Sponsor Protocol Number: qmul010610 Start Date*: 2011-01-07
    Sponsor Name:Barts and the London School of Medicine and Dentistry, Queen Mary University of London
    Full Title: Effects of a tailored dose of varenicline on post-quitting urges to smoke
    Medical condition: Tobacco dependence (smoking cessation)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-001099-20 Sponsor Protocol Number: CPR-EFC5515-EN-E02 Start Date*: 2006-05-18
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: An international, seven-week, double blind, placebo-controlled, two parallel group study to assess the efficacy of dianicline 40 mg bid as an aid to smoking cessation in cigarette smokers
    Medical condition: Cigarette smokers willing to quit
    Disease: Version SOC Term Classification Code Term Level
    8.1 10057852 Nicotine dependence LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) NO (Completed) DK (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-001237-65 Sponsor Protocol Number: Start Date*: 2017-06-29
    Sponsor Name:Queen Mary University of London, Joint Research Management Office
    Full Title: Helping Pregnant smokers quit: A multi-centre RCT of electronic cigarettes and nicotine patches
    Medical condition: Tobacco dependence/smoking cessation
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10057852 Nicotine dependence PT
    20.0 100000004869 10008374 Cessation of smoking LLT
    Population Age: Adults Gender: Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2008-006433-28 Sponsor Protocol Number: RG_08_082_a02 Start Date*: 2009-01-20
    Sponsor Name:University of Birmingham
    Full Title: Rapid reduction versus abrupt quitting for smokers who want to stop soon: a randomised controlled non-inferiority trial.
    Medical condition: Smoking and nicotine addiction.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10056478 Nicotine addiction LLT
    9.1 10056484 Nicotine craving LLT
    9.1 10057852 Nicotine dependence LLT
    9.1 10008374 Cessation of smoking LLT
    9.1 10053325 Smoking cessation therapy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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