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Clinical trials for Stenosis

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    442 result(s) found for: Stenosis. Displaying page 1 of 23.
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    EudraCT Number: 2007-003162-17 Sponsor Protocol Number: 04062007 Start Date*: 2007-10-11
    Sponsor Name:Markku Kupari
    Full Title: Lääkehoito aorttaläpän stenoosin ehkäisyssä Angiotensiinireseptorin salpaajan vaikutukset stenoottisen aorttaläpän tulehdukseen, fibroosiin ja kalkkiutumiseen
    Medical condition: Aorttaläpän stenoosi
    Disease: Version SOC Term Classification Code Term Level
    9.1 10002918 Aortic valve stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005962-36 Sponsor Protocol Number: inv driven trial with RVG26872 Start Date*: 2006-03-22
    Sponsor Name:
    Full Title: Prospective randomized trial of effects of rosuvastatin on the progression of stenosis in adult patients with congenital aortic stenosis
    Medical condition: congenital aortic stenosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-013259-31 Sponsor Protocol Number: 6232 Start Date*: 2009-12-29
    Sponsor Name:UMC Utrecht
    Full Title: A multicenter double blind placebo-controlled randomised trial for benign esophageal anastomotic strictures: Savary dilation vs savary dilation with Triamcinolon
    Medical condition: Patients with first time dysphagia (grade 2-4) due to a benign anastomotic esophageal stricture
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015449 Esophageal stricture LLT
    9.1 10030199 Oesophageal stricture LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000111-26 Sponsor Protocol Number: MEIN/10/Ran-Did/002 Start Date*: 2011-07-01
    Sponsor Name:A. MENARINI PHARMA U.K.,
    Full Title: Effect of late sodium current inhibition on MRI measured diastolic dysfunction and myocardial perfusion reserve in aortic stenosis - a proof of concept study.
    Medical condition: Aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-003391-39 Sponsor Protocol Number: 9026 Start Date*: 2012-10-26
    Sponsor Name:University Hospital of Montpellier
    Full Title: Ballon aortic valvuloplasty performed without heparin to decrease vascular and bleeding complications of the procedure
    Medical condition: Aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2016-002291-27 Sponsor Protocol Number: RIVAR-CTP-01 Start Date*: 2016-11-07
    Sponsor Name:Aalborg University Hospital
    Full Title: Randomized trial of aspirin versus rivaroxaban after replacement of the aortic valve with a biological valve prosthesis
    Medical condition: Aortic valve stenosis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-018490-38 Sponsor Protocol Number: 1616 Start Date*: 2010-06-14
    Sponsor Name:Anæstesiologisk Afd. I, Skejby Sygehus
    Full Title: Effekten af levosimendan på systolisk deformation og diastolisk funktion hos patienter med operationskrævende aortastenose og svær hypertrofi af venstre ventrikel
    Medical condition: Aortaklapsstenose Diastolisk dysfunktion
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002906 Aortic stenosis LLT
    12.1 10052337 Diastolic dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-003927-13 Sponsor Protocol Number: REAC-TAVI2 Start Date*: 2021-10-15
    Sponsor Name:Fundación Biomédica Galicia Sur
    Full Title: Single antiplatelet therapy with Ticagrelor vs Aspirin after Transcatheter Aortic Valve Implantation: multicenter randomized clinical trial. REAC TAVI 2
    Medical condition: Symptomatic severe aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10077017 TAVI LLT
    20.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    20.1 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-005856-33 Sponsor Protocol Number: AT10008 Start Date*: 2007-02-13
    Sponsor Name:The Department of Molecular Medicin and Surgery, P9:03, Karolinska Institutet
    Full Title: Local Glucocorticoid Injektion in the Treatment of Benign Oesophageal Strictures, a Randomized Clinical Study
    Medical condition: Patients with benign oesophageal strictures and symptoms where dilatation of the stricture is planned.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10030199 Oesophageal stricture LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001853-41 Sponsor Protocol Number: 57698 Start Date*: 2018-09-19
    Sponsor Name:Academic Medical Center
    Full Title: Intensive endoscopic therapy versus conventional treatment for untreated benign anastomotic strictures after esophagectomy: a pilot and randomized controlled trial
    Medical condition: Benign esophagogastric anastomotic strictures after esophagectomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004856 10030199 Oesophageal stricture LLT
    20.0 100000004856 10015449 Esophageal stricture LLT
    20.0 10042613 - Surgical and medical procedures 10030215 Oesophagectomy PT
    20.0 10042613 - Surgical and medical procedures 10015460 Esophagectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2017-002799-18 Sponsor Protocol Number: ICICOR-2017-01 Start Date*: 2017-12-27
    Sponsor Name:José Alberto San Román Calvar
    Full Title: Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI)
    Medical condition: Severe aortic stenosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10002906 Aortic stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007085-38 Sponsor Protocol Number: 1012007 Start Date*: 2008-05-05
    Sponsor Name:Kuopio University Hospital
    Full Title: Estääkö postoperatiivisesti annettu kortikosteroidi hiippaläppäleikkauksen jälkeisen eteisvärinän ilmaantumista?
    Medical condition: Tutkimukseen otetaan 220 peräkkäistä hiippaläppäleikkaukseen tulevaa potilasta, joilla ennen leikkausta on sinusrytmi. Tutkimukseen valittavilla potilailla on siis sydämen hiippaläpän leikkaushoito...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027729 Mitral valve insufficiency and aortic valve stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-002015-17 Sponsor Protocol Number: 2016-002015-17 Start Date*: 2017-03-10
    Sponsor Name:Odense University Hospital
    Full Title: Low-flow Low-gradient Aortic Stenosis – Diagnostic Usefullness of Ivabradine
    Medical condition: Aortic valve stenosis with reduced ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004653-24 Sponsor Protocol Number: ARBAS041218 Start Date*: 2020-06-15
    Sponsor Name:Odense Universitets Hospital
    Full Title: Impact of an Angiotensin Receptor Blocker in Aortic Stenosis – A Randomized Controlled Trial
    Medical condition: Aortic valve stenosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000608-40 Sponsor Protocol Number: No-DAPT-TAVI Start Date*: 2018-07-06
    Sponsor Name:AOU DI BOLOGNA POLICLINICO S.ORSOLA-MALPIGHI
    Full Title: Aspirin versus Aspirin plus Clopidogrel in Patients Undergoing Transcatheter Aortic Valve Replacement: a Randomized Multicenter Study
    Medical condition: valvular aortic stenosis submitted to TAVI
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-005296-18 Sponsor Protocol Number: BI8021_5101 Start Date*: 2007-08-27
    Sponsor Name:Heinrich-Heine-Universität Duesseldorf
    Full Title: Einsatz von Haemateâ HS bei Patienten mit schweren Blutungskomplikationen bei Herzklappenersatz wegen Aortenstenose HAVAS-Studie (Haemate HS in patients with severe bleeding undergoing valve repl...
    Medical condition: Intraoperative Blutungsneigung während des Aortenklappenersatzes bei Patienten mit isolierter valvulärer Aortenstenose oder kombiniertem Aortenvitium mit führender Stenose Klassifikationscode ICD1...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009730 Coagulation defects, other and unspecified LLT
    9.1 10002918 Aortic valve stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005630-21 Sponsor Protocol Number: D5130C00173 Start Date*: 2016-06-30
    Sponsor Name:National and Kapodistrian University of Athens
    Full Title: A Prospective, Multicentre, Randomized, Open Label, Blinded Endpoint, Phase 3 Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr with Acetylsalicylic Acid versus CLopidogrel with Ac...
    Medical condition: Preventing cerebrovascular embolic events during the TAVI procedure
    Disease: Version SOC Term Classification Code Term Level
    19.0 10007541 - Cardiac disorders 10002918 Aortic valve stenosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-002650-38 Sponsor Protocol Number: Pre65 Start Date*: 2008-07-01
    Sponsor Name:Organisation name was not entered
    Full Title: Vähentääkö pregabaliini opioidikipulääkityksen tarvetta ja kroonisen kivun esiintyvyyttä alle 65-vuotiailla potilailla sydänleikkauksen jälkeen?
    Medical condition: Tutkimukseen otetaan potilaan suostumuksella alle 65-vuotiaita avosydänleikkauk-seen joko koronaariohitus- tai sydämen läppärekonstruktioon tulevia potilaita, jotka leikatataan perfuusioleikkauksena.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011099 Coronary disease LLT
    9.1 10002906 Aortic stenosis LLT
    9.1 10027716 Mitral insufficiency LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-000929-59 Sponsor Protocol Number: MultiH/BRA/708 Start Date*: Information not available in EudraCT
    Sponsor Name:Bracco ALTANA Pharma GmbH
    Full Title: INTRAINDIVIDUAL CROSS-OVER STUDY TO COMPARE MULTIHANCE® AND MAGNEVIST® AT A DOSE OF 0.1 MMOL/KGBW IN CERVICO-CEREBRAL MR ANGIOGRAPHY AND CEREBRAL MR PERFUSION IMAGING AT 3 TESLA IN PATIENTS WITH CA...
    Medical condition: Carotid artery stenosis and scheduled for MRA, for MR perfusion examination and for an elective stent treatment
    Disease: Version SOC Term Classification Code Term Level
    8.1 10007687 Carotid artery stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-007041-39 Sponsor Protocol Number: IOP-108 Start Date*: 2008-12-18
    Sponsor Name:BRACCO IMAGING
    Full Title: A Phase II Multicenter Randomized Double-Blind Dose-Finding Study of Iopamidol Injection 370 in Multidetector Computed Tomographic Angiography (MDCTA) in Patients with Suspected Coronary Artery Ste...
    Medical condition: Patients who have known or suspected CAD and suspected significant (> 50%) coronary artery stenosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011089 Coronary artery stenosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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