Flag of the European Union EU Clinical Trials Register Help

Clinical trials for carvedilol

The European Union Clinical Trials Register allows you to search for protocol and results information on:
  • interventional clinical trials that are conducted in the European Union (EU) and the European Economic Area (EEA);
  • clinical trials conducted outside the EU / EEA that are linked to European paediatric-medicine development.
  • Learn   more about the EU Clinical Trials Register   including the source of the information and the legal basis.


    The EU Clinical Trials Register currently displays   42567   clinical trials with a EudraCT protocol, of which   7008   are clinical trials conducted with subjects less than 18 years old.
    The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).


    Phase 1 trials conducted solely in adults and that are not part of an agreed PIP are not public in the EU CTR (refer to European Guidance 2008/C 168/02   Art. 3 par. 2 and   Commission Guideline 2012/C 302/03,   Art. 5) .

    Clinical Trials marked as "Trial now transitioned" were transitioned to the Clinical Trial Regulation 536/2014 and can be further followed in the Clinical Trial Information System  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    43 result(s) found for: carvedilol. Displaying page 1 of 3.
    1  2  3  Next»
    EudraCT Number: 2009-014643-36 Sponsor Protocol Number: MeBe/08/NEB-MICR/001 Start Date*: 2010-04-23
    Sponsor Name:MENARINI Benelux NV/SA
    Full Title: Effects Of The Administration Of Nebivolol Versus Carvedilol On Microcirculatory Endothelial Function, Arterial Stiffness And Wave Reflection In Healthy Volunteers” (NeCaMic-study)
    Medical condition: Microcirculatory Endothelial Function, Arterial Stiffness And Wave Reflection
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: BE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-002754-62 Sponsor Protocol Number: 2004-001 Start Date*: 2006-06-20
    Sponsor Name:University of Göttingen; Dep. of Clinical Pharmacology
    Full Title: Development of CYP2D6 genotype based dosage guidelines for the beta-blockers metoprolol and carvedilol based on hepatic clearance and resting and exercise heart rate reduction
    Medical condition: Healthy male and female volunteers
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-006534-17 Sponsor Protocol Number: CL-EG-006 Start Date*: 2007-01-26
    Sponsor Name:Egalet a/s
    Full Title: A Phase II, Multi-center, Multiple-dose, Double-blind, Randomized, Crossover Study Comparing the Pharmacodynamic Effects of a Once-daily Controlled-Release Carvedilol (CRC; Egalet® Formulation) an...
    Medical condition: Hypertension
    Disease: Version SOC Term Classification Code Term Level
    8.1 10020772 Hypertension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2011-006208-11 Sponsor Protocol Number: 1544?H?254 Start Date*: 2012-04-18
    Sponsor Name:CAIBER
    Full Title: A randomized, controlled multicenter clinical trial comparing endoscopic band ligation versus oral carvedilol in the primary prophylaxis of esophageal variceal bleeding in patients with cirrosis
    Medical condition: Esophageal variceal bleeding in patients with cirrhosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-003075-12 Sponsor Protocol Number: 290478 Start Date*: Information not available in EudraCT
    Sponsor Name:Department Of Paediatric Cardiology
    Full Title: Effect of carvedilol on left ventricular systolic and diastolic function and the neurohormonal axis in patients with Duchenne muscular dystrophy and left ventricular dysfunction.
    Medical condition: Duchenne muscular dystrophy is an X-linked inherited disorder which primarily affects skeletal muscle through a mutation in dystrophin which maps to the long arm of the X chromosome (Xp21). Patient...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002509-78 Sponsor Protocol Number: BOPPP Start Date*: 2019-04-24
    Sponsor Name:Kings College Hospital NHS Foundation Trust
    Full Title: Beta-blockers Or Placebo for Primary Prophylaxis of oesophageal varices (BOPPP Trial). A blinded, UK multi-centre, clinical effectiveness and cost-effectiveness randomised controlled trial.
    Medical condition: Liver cirrhosis with small oesophageal varices
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10024667 Liver cirrhosis LLT
    21.1 100000004856 10055489 Esophageal varices in cirrhosis of liver LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-004438-18 Sponsor Protocol Number: MeIn/06/NEB-DIA/001 Start Date*: 2008-04-08
    Sponsor Name:A. Menarini Farmaceutica Internazionale s.r.l.
    Full Title: Comparative effects of Nebivolol and Carvedilol on orthostatic hypotension in hypertensive patients with type 2 diabetes mellitus (DIANECA)
    Medical condition: Orthostatic hypotension in hypertensive patients with type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031127 Orthostatic hypotension LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) IE (Prematurely Ended) LV (Prematurely Ended) AT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023395-61 Sponsor Protocol Number: 2010-ECOFA-01 Start Date*: 2011-07-14
    Sponsor Name:Isidre Vilacosta
    Full Title: Estudio de la eficacia de los corticoides en la prevención de la fibrilación auricular tras cirugía cardiaca Corticosteroids for the prevention of atrial fibrillation after cardiac surgery: a ra...
    Medical condition: Prevención de la fibrilación auricular tras cirugía cardica de revascularización coronaria, valvular o ambas Prevention of atrial fibrillation after cardiac surgery in patients undergoing corona...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-006604-38 Sponsor Protocol Number: OVERCOME Start Date*: 2008-02-22
    Sponsor Name:HOSPITAL CLINIC
    Full Title: Prevención de la disfunción ventricular con enalapril y carvedilol en pacientes sometidos a quimioterapia intensiva para el tratamiento de hemopatías malignas. Prevention of ventricular dysfunctio...
    Medical condition: Disfunción ventricular post quimioterapia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10059056 Ventricular dysfunction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-000957-47 Sponsor Protocol Number: 12052004 Start Date*: 2007-11-22
    Sponsor Name:Charité
    Full Title: Comparison of Bisoprolol and Carvedilol in elderly patients with heart failure. A randomised doubleblind multicenter trial
    Medical condition: Patients, 65 years or older, suffering from chronic heart failure and who are so far not treated with betablockers or treated with a low dose betablocker (<1/4 standard dose)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2007-003781-17 Sponsor Protocol Number: CCM S78/407 Start Date*: 2007-07-16
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: COMPARED EFFECTS OF THREE DIFFERENT BETA BLOCKERS (CARVEDILOL, BISOPROLOL AND NEBIVOLOL) ON EXERCISE CAPACITY, PULMONARY FUNCTION AND RESPONSE TO HYPOXIA IN CHRONIC HEART FAILURE
    Medical condition: chronic heart failure
    Disease: Version SOC Term Classification Code Term Level
    6.1 10007558 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001509-40 Sponsor Protocol Number: BETAVASC-IV-08-1 Start Date*: 2008-10-18
    Sponsor Name:Hungarian Kidney Foundation
    Full Title: Effects of beta blockers on central arterial pressure and vascular stiffness
    Medical condition: Patients with hypertension and/or ischemic heart disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003286-21 Sponsor Protocol Number: SVUH-UCD-LEAD/CAR/01/2014 Start Date*: 2015-08-17
    Sponsor Name:University College Dublin
    Full Title: A multicentre, interventional, parallel group, randomised, open-label, exploratory study to assess the earlier introduction of Ivabradine in the Management of Systolic Dysfunction Heart Failure. Th...
    Medical condition: Heart Failure with reduced ejection fraction and borderline systolic blood pressure.
    Disease: Version SOC Term Classification Code Term Level
    18.1 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2007-001994-27 Sponsor Protocol Number: 2006B180 Start Date*: 2007-09-03
    Sponsor Name:Netherlands Heart Foundation
    Full Title: The effect of beta-adrenergic receptor blockade on sympathetic activity and coagulation in patients with heart failure (BACH-F study)
    Medical condition: Congestive heart failure
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010684 Congestive heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006008-11 Sponsor Protocol Number: ANDA2 Start Date*: 2012-08-22
    Sponsor Name:Tayside Clinical Trials Unit, University of Dundee
    Full Title: Evaluation of effects of chronic dose exposure to cardioselective and non-cardioselective beta blockers on measures of cardiopulmonary function in moderate to severe COPD.
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10009026 Chronic obstructive airways disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-000896-99 Sponsor Protocol Number: AC16148 Start Date*: 2017-06-20
    Sponsor Name:University of Edinburgh [...]
    1. University of Edinburgh
    2. NHS Lothian
    Full Title: A multicentre prospective randomised open-label blinded end-point controlled trial of high-sensitivity cardiac troponin I-guided combination angiotensin receptor blockade and beta blocker therapy t...
    Medical condition: Myocardial toxicity and the development of left ventricular systolic dysfunction
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004848 10007612 Cardiac troponin I increased LLT
    20.0 100000004849 10069501 Left ventricular systolic dysfunction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-007236-18 Sponsor Protocol Number: 1484/08 Start Date*: 2008-12-01
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effects of cardioprotective therapy, carvedilol vs ramipril, in patients affected by Duchenne and Becker muscular dystrophy. Clinical significance and prognostic value of Cardiac Magnetic Resonance...
    Medical condition: Duchenne and Becher muscular dystrophy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10013801 Duchenne muscular dystrophy LLT
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-023979-25 Sponsor Protocol Number: 2010/353 Start Date*: 2011-01-03
    Sponsor Name:Department of Nephrology
    Full Title: Role of renal and systemic vascular resistance for progression of chronic kidney disease
    Medical condition: We want to investigate whether increased vasodilitation ( angiotensin converting enzyme inhibitor and calcium channel blocker) compared to standard treatment ( beta-blocker and angiotensin convert...
    Disease: Version SOC Term Classification Code Term Level
    13.1 10047065 - Vascular disorders 10063097 Peripheral vasodilatation LLT
    13.1 10047065 - Vascular disorders 10047141 Vasodilatation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011163-36 Sponsor Protocol Number: FIHGM-09-02 Start Date*: 2009-08-25
    Sponsor Name:FUNDACION PARA LA INVESTIGACION BIOMEDICA HOSPITAL GREGORIO MARAÑON
    Full Title: Ablación de sustrato de las taquicardias ventriculares monomórficas versus fármacos antiarrítmicos en pacientes con descargas apropiadas de desfibrilador automático implantable
    Medical condition: PREVENCION DE ARRITMIAS EN CARDIOPATIA ISQUEMICA
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-000890-29 Sponsor Protocol Number: Destro Start Date*: 2011-03-28
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Instrumental and clinical effects of withdrawal of beta blockers therapy in patients with heart failure and right ventricular dysfunction''
    Medical condition: heart failure
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10011949 Decompensation cardiac LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    1  2  3  Next»
    Query did not match any studies.
    For support, visit the EMA Service Desk , log in using your EMA account and open a ticket specifying "EU CTR" in your request.
    If you do not have an account, please visit the EMA Account management page page click on "Create an EMA account" and follow the instructions.
    The status of studies in GB is no longer updated from 1.1.2021
    For the UK, as from 1.1.2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI
    EU Clinical Trials Register Service Desk: https://servicedesk.ema.europa.eu
    European Medicines Agency © 1995-2022 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    Legal notice
    EMA HMA