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Clinical trials for modafinil

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

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    37 result(s) found for: modafinil. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2005-002209-22 Sponsor Protocol Number: 7197 Start Date*: 2005-09-23
    Sponsor Name:University Hospitals of Leicester NHS Trust
    Full Title: A randomised, placebo-controlled, rising-dose crossover study to evaluate the effectiveness of modafinil in the management of fatigue in fibromyalgia
    Medical condition: Fibromyalgia
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002699-13 Sponsor Protocol Number: EK 070/05 Start Date*: 2005-11-25
    Sponsor Name:Department of Palliative Medicine, RWTH Aachen
    Full Title: Modafinil in der Behandlung von Müdigkeit bei Tumorpatienten - eine randomisierte doppelblinde N=1 Studie
    Medical condition: advanced cancer disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007033-41 Sponsor Protocol Number: 1200 Start Date*: Information not available in EudraCT
    Sponsor Name:Hephata-Klinik
    Full Title: Pilot study on therapeutic efficacy of modafinil in idiopathic hypersomnie
    Medical condition: To test the efficacy, tolerability and safety of modafinil for the treatment of of excessiv daytime sleepiness in patients with idiopathic hypersomnia without long sleep time.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005107-13 Sponsor Protocol Number: 002083935121 Start Date*: 2015-01-27
    Sponsor Name:Epsom and St Helier University Hospitals NHS Trust R&D Dpt
    Full Title: A pilot study of the use of oral modafinil added to standard care in hypercapnic respiratory failure in COPD
    Medical condition: Hypercapnic respiratory failure in COPD
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2004-005010-37 Sponsor Protocol Number: 62 Start Date*: 2005-08-16
    Sponsor Name:Suffolk Mental Health Partnerships Trust
    Full Title: Enhancing cognition in bipolar disorder
    Medical condition: Bipolar affective disorder, currently in remission
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003102-10 Sponsor Protocol Number: modafinil01 Start Date*: 2009-01-23
    Sponsor Name:fonds NutsOhra
    Full Title: The effect of modafinil on fatigue, cognition and functional connectivity in low-grade glioma patients: a double-blind randomized trial.
    Medical condition: fatigue in low-grade glioma patients
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003196-21 Sponsor Protocol Number: SE 03 Start Date*: 2008-01-22
    Sponsor Name:Technische Universität München
    Full Title: Enhancing the Therapeutic Efficacy of Sleep Deprivation by Modafinil - a double blind, randomized, placebo-controlled, monocentric phase II study
    Medical condition: Inpatients of the Psychiatric Hospital of the Technical University of Munich Diagnoses: - Depressive episode with somatic symptoms (ICD-10: F32.01, F32.11, F32.21) - Recurrent depressive disorder...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005035-41 Sponsor Protocol Number: THN102-201 Start Date*: 2018-05-29
    Sponsor Name:Theranexus SA
    Full Title: SAFETY AND EFFICACY OF THN102 ON SLEEPINESS IN NARCOLEPTIC PATIENTS
    Medical condition: This Proof-of-Concept, Phase IIa trial with THN102 should collect a sufficient body of information to assess efficacy and safety profile of THN102 versus modafinil alone in patient with a diagnosis...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10028713 Narcolepsy PT
    20.0 10029205 - Nervous system disorders 10028715 Narcolepsy with cataplexy LLT
    20.0 10029205 - Nervous system disorders 10007738 Cataplexy and narcolepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2017-002288-16 Sponsor Protocol Number: MOCAFFE Start Date*: 2018-01-24
    Sponsor Name:Center for Man in Aviation
    Full Title: Effects of Modafinil and Caffeine during the circadian trough on vigilance in healthy RNLAF aircrew: a randomized controlled trial
    Medical condition: fatigue in healthy aircew
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2005-000547-28 Sponsor Protocol Number: 070774 Start Date*: 2006-01-15
    Sponsor Name:Department of Psychiatry; Section of Sleep Research and Pharmacopsychiatry
    Full Title: EEG and ERP tomography by means of LORETA (Low-Resolution Brain Electromagnetic Tomography) identifying essential brain regions for vigilance and cognition in narcolepsy: double-blind, placebo-cont...
    Medical condition: Patients complaining of excessive daytime sleepiness will be recruited from our sleep clinics and will be subjected to neuropsychiatric, physical, laboratory and neurophysiological screening examin...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-006486-88 Sponsor Protocol Number: Modafinil/lung/01 Start Date*: 2009-03-17
    Sponsor Name:University of Oxford
    Full Title: Modafinil for the treatment of fatigue in lung cancer: a multicentre, randomised, double-blinded, placebo-controlled trial
    Medical condition: The symptom of fatigue in patients with non-small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029514 Non-small cell lung cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-003882-17 Sponsor Protocol Number: MKM Start Date*: 2013-05-06
    Sponsor Name:Charité Universitaetsmedizin Berlin
    Full Title: Effects of modafinil, caffeine and methylphenidate on functional brain activity and cognitive performance in healthy subjects: a randomized, placebo-controlled, double-blind fMRI study.
    Medical condition: healthy volunteers
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2007-006262-16 Sponsor Protocol Number: P070150 Start Date*: 2009-02-05
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Transporteur de la Dopamine (DAT) dans les traitements pharmacologiques de la dépendance à la cocaïne
    Medical condition: Sujets dépendants à la cocaïne, hospitalisés pour sevrage thérapeutique.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10001125 toxicomanie PT
    Population Age: Adults Gender: Male
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013020-23 Sponsor Protocol Number: RAA09-002 Start Date*: 2010-03-23
    Sponsor Name:King's College London
    Full Title: A Pilot study of cognitive enhancer and cognitive training combination – Testing a therapeutic paradigm for cognitive impairment in schizophrenia
    Medical condition: Cognitive impairment associated with schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10039626 Schizophrenia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-007845-29 Sponsor Protocol Number: P07-07 / BF 2.649 Start Date*: Information not available in EudraCT
    Sponsor Name:Bioprojet
    Full Title: Prospective, randomized, double-blind study, parallel-group, multi-center trial assessing the effects of escalating doses of BF2.649 and BF2.649 add on Modafinil on cataplexy in patients with narco...
    Medical condition: Cataplexy in patients with narcolepsy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028713 Narcolepsy LLT
    9.1 10048322 Narcolepsy aggravated LLT
    9.1 10021235 Idiopathic narcolepsy LLT
    9.1 10007737 Cataplexy LLT
    9.1 10048323 Cataplexy aggravated LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) FR (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-003271-35 Sponsor Protocol Number: KU-AIM-01-2018 Start Date*: 2019-01-07
    Sponsor Name:University of Copenhagen
    Full Title: STUDY OF ATTENTION AND IMPULSIVITY IN HEALTHY HUMAN VOLUNTEERS
    Medical condition: Attentional deficits and impulsive behaviour. These symptoms are common in attention deficit hyperactivity disorder, but also other conditions affecting the central nervous system such as Alzheimer...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-005538-59 Sponsor Protocol Number: 22-09-2008 Start Date*: 2009-02-18
    Sponsor Name:ZonMw
    Full Title: Impulsivity, a risk factor in relapse to substance use disorder: investigating neural substrates before and after pharmacological challenges
    Medical condition: Alcohol dependence Cocaine dependence
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-005510-20 Sponsor Protocol Number: C10953/1100 Start Date*: 2013-03-07
    Sponsor Name:Cephalon, Inc.
    Full Title: A Randomized, Open-Label Study to Characterize the Pharmacokinetics, Pharmacodynamics, and Safety of Single and Multiple Doses of Armodafinil (50, 100, and 150 mg/day) in Children and Adolescents w...
    Medical condition: Excessive Sleepiness associated with Narcolepsy
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-007555-14 Sponsor Protocol Number: C10953/2032/DP/US Start Date*: 2008-08-15
    Sponsor Name:Cephalon, Inc.
    Full Title: An 8-Week, Double-Blind, Placebo-Controlled, Parallel-Group, Fixed-Dosage Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/day) as Adjunctive Therapy in Adults With Major ...
    Medical condition: Major Depression Associated With Bipolar I Disorder
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057840 Major depression LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2004-002505-74 Sponsor Protocol Number: CEP1538/3034/ES/MN Start Date*: 2005-01-05
    Sponsor Name:Cephalon Europe, A Division of Cephalon UK Limited
    Full Title: A 6 month open-label, flexible-dosage study to assess the safety and effectiveness of PROVIGIL® (Modafinil) treatment in children and adolescents with excessive sleepiness associated with narcoleps...
    Medical condition: Excessive sleepiness associated with Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10015595 LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed) FI (Completed) GB (Completed) ES (Completed) IT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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