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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,988 result(s) found. Displaying page 108 of 550.
    «« First « Previous 104  105  106  107  108  109  110  111  112  Next» Last»»
    EudraCT Number: 2013-002966-38 Sponsor Protocol Number: CCD-01535BC1-02 Start Date*: 2013-11-20
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A PHASE II, PARTIAL-BLIND, RANDOMIZED, PLACEBO-CONTROLLED, 5-WAY CROSS-OVER CLINICAL PHARMACOLOGY STUDY TO EVALUATE THE PHARMACODYNAMICS OF BDP/B17MP AND FORMOTEROL ACROSS TWO DIFFERENT DOSE LEVELS...
    Medical condition: COPD patients
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004855 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005570-56 Sponsor Protocol Number: GLINT Start Date*: 2014-01-28
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: Glucose Lowering In Non-diabetic hyperglycaemia Trial (GLINT) - a randomised controlled trial to establish the effectiveness and cost-effectiveness of metformin in preventing cardiovascular events ...
    Medical condition: Non-diabetic hyperglycaemia (elevated blood glucose levels below the diagnostic threshold for diabetes) and high risk of cardiovascular disease (>20% risk over 10 years)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-005565-20 Sponsor Protocol Number: QMUL111111 Start Date*: 2012-05-02
    Sponsor Name:QUEEN MARY, UNIVERSITY OF LONDON
    Full Title: Comparison of the effects of the electronic cigarette and nicotine inhalator on tobacco withdrawal symptoms over 24 hours of abstinence
    Medical condition: Nicotine withdrawal state
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10056484 Nicotine craving LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005581-37 Sponsor Protocol Number: 5946 Start Date*: 2012-08-06
    Sponsor Name:The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Full Title: Efficacy of Switch to Lopinavir/Ritonavir in Improving Cognitive function in Efavirenz treated patients
    Medical condition: Cognitive function and sleep pattern in HIV-1 patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021428 - Immune system disorders 10021425 Immune system disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2014-001784-13 Sponsor Protocol Number: ISRCTN91422391 Start Date*: 2014-12-29
    Sponsor Name:Queen Mary University of London
    Full Title: PROVENT: A randomised, double blind, placebo controlled feasibility study to examine the clinical effectiveness of aspirin and/or Vitamin D3 to prevent disease progression in men on active surveill...
    Medical condition: Prostate cancer disease progression
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10060862 Prostate cancer PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-000292-15 Sponsor Protocol Number: S241-GB-10 Start Date*: 2006-03-13
    Sponsor Name:Stiefel Laboratories Maidenhead Ltd.
    Full Title: A Phase II, Single-Centre, Randomised,Double-Blind, Parallel Group, CPO Solution, Dose Range Finding Study in Subjects with Seborrhoeic Dermatitis of the Scalp
    Medical condition: Seborrhoeic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039793 Seborrhoeic dermatitis LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-002068-25 Sponsor Protocol Number: CSLCT-NHF-05-13 Start Date*: 2006-05-23
    Sponsor Name:CSL Limited
    Full Title: A Single Site, Open-Label Study to Evaluate the Immunogenicity and Safety of Enzira in Healthy 'Adults' aged >18 to <60 years and in Healthy 'Older Adults' aged >60 years for the 2006/2007 Northern...
    Medical condition: Prophylaxis of influenza
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004902-16 Sponsor Protocol Number: Start Date*: 2007-10-01
    Sponsor Name:Royal Bournemouth Hospital
    Full Title: A randomized phase II trial to determine whether the application of imiquimod cream to the vaccination site can improve the immune responsiveness to influenza vaccination in patients with untreated...
    Medical condition: Early stage (Binet stage A) Patients with chronic lymphocytic leukaemia and control group of age and sex matched healthy volunteers
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008968 Chronic lymphocytic leukaemia stage A(0) LLT
    9.1 10008969 Chronic lymphocytic leukaemia stage A(I) LLT
    9.1 10008970 Chronic lymphocytic leukaemia stage A(II) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-003291-19 Sponsor Protocol Number: VAI01 Start Date*: 2009-07-30
    Sponsor Name:University of Dundee
    Full Title: A proof of concept study to evaluate if concomitant topical intranasal steroid prevents tolerance and rebound congestion due to regular oxymetazoline in persistent allergic rhinitis
    Medical condition: Allergic Rhinitis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10001723 Allergic rhinitis LLT
    9.1 10039090 Rhinitis medicamentosa LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001811-40 Sponsor Protocol Number: PAW01 Start Date*: 2008-08-27
    Sponsor Name:The University of Dundee
    Full Title: A Proof of Concept Study to Evaluate the Additive Effects of HFA-BDP (Qvar) to fluticasone/salmeterol (Seretide) on Surrogate Markers of Small and Large Airway Inflammation in Refractory Asthma
    Medical condition: Severe refractory asthma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-005566-39 Sponsor Protocol Number: 06_DOG07_64 Start Date*: 2008-03-05
    Sponsor Name:Christie Hospital NHS Foundation Trust
    Full Title: Concurrent chemoradiotherapy for stage III non small cell lung cancer followed by consolidation pemetrexed: a phase II study
    Medical condition: Non-small cell lung cancer, stage III
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029520 Non-small cell lung cancer stage IIIA LLT
    9.1 10029521 Non-small cell lung cancer stage IIIB LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-000517-30 Sponsor Protocol Number: 3065 Start Date*: 2009-03-26
    Sponsor Name:The Royal Marsden Hospital NHS Trust
    Full Title: A multicentre randomised phase II clinical study of UFT/leucovorin (LV), radiotherapy with or without cetuximab following induction gemcitabine plus capecitabine in patients with locally advanced p...
    Medical condition: Locally-advanced (unresectable) pancreatic adenocarcinoma, undifferentiated carcinoma or non-small cell carcinoma.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033606 Pancreatic cancer non-resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-001723-19 Sponsor Protocol Number: EC001(MenC1) Start Date*: 2006-06-02
    Sponsor Name:University of Bristol
    Full Title: AN OPEN LABEL, SINGLE CENTRE PILOT STUDY TO EVALUATE THE KINETICS OF THE SYSTEMIC B-CELL IMMUNE RESPONSE TO A MENINGOCOCCAL SEROGROUP C CONJUGATE VACCINE IN HEALTHY ADULTS
    Medical condition: Meningococcal serogroup C infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-008141-37 Sponsor Protocol Number: diab123v1.0 Start Date*: 2009-09-08
    Sponsor Name:Sherwood Forest Hospitals Foundation Trust
    Full Title: Effects of Exenatide on excess daytime sleepiness (EDS), wakefulness and driving performance in obese type-2 diabetes patients without sleep apnea – proof of concept study
    Medical condition: sleepiness and lethargy among obese patients with diabetes
    Disease: Version SOC Term Classification Code Term Level
    1 10012594 LLT
    1 10029883 LLT
    Population Age: Adults Gender: Male
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2007-002137-37 Sponsor Protocol Number: T-004 Start Date*: 2007-07-13
    Sponsor Name:TRIO Medicines Ltd
    Full Title: Does adding YF476 to amoxicillin and clarithromycin aid eradication of H. pylori from healthy carriers?
    Medical condition: H pylori carriage in healthy adults
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063593 Helicobacter pylori identification test positive LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-003285-42 Sponsor Protocol Number: PHT/2005/37 Start Date*: 2005-11-28
    Sponsor Name:Portsmouth Institution Medicine, Health & Social Care, Portsmouth University [...]
    1. Portsmouth Institution Medicine, Health & Social Care, Portsmouth University
    2. Research & Development Unit, Queen Alexandra Hospital
    Full Title: A RCT to test the analgesic efficacy of topical morphine on minor and partial thickness burns in A&E
    Medical condition: Minor superficial and partial thickness burns <5% body surface area.
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-003596-12 Sponsor Protocol Number: C/21/07 Start Date*: 2008-01-28
    Sponsor Name:Imperial College of Science Technology and Medicine
    Full Title: A neoadjuvant study of chemotherapy versus endocrine therapy in postmenopausal patients with primary breast cancer
    Medical condition: This trial will involve postmenopausal patients with histologically confirmed breast tumours in whom it is felt cytoreductive systemic therapy would enable conservative surgery to be carried out.
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006187 Breast cancer PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: Removed from public view
    EudraCT Number: 2007-000774-23 Sponsor Protocol Number: CCD-0701-PR-0020 Start Date*: 2007-05-10
    Sponsor Name:Chiesi Farmaceutici S.p.A
    Full Title: EVALUATION OF CARDIAC SAFETY, TOLERABILITY AND EFFICACY OF CUMULATIVE DOSES OF CHF5188 pMDI (FIXED COMBINATION BUDESONIDE/CARMOTEROL 200/1 µg) COMPARED TO SAME CUMULATIVE DOSES OF CARMOTEROL pMDI A...
    Medical condition: Stable persistent asthma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000056-14 Sponsor Protocol Number: 06/DTD/3791E Start Date*: 2008-03-03
    Sponsor Name:Cardiff University
    Full Title: Determination of method-specific normal cortisol and adrenal hormone responses to the short Synacthen test
    Medical condition: Normal, healthy volunteers to establish a reference range for the synacthen test, plus patients with hypoadrenalism/hypopituitarism
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020936 Hypoadrenalism LLT
    9.1 10021067 Hypopituitarism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-006362-41 Sponsor Protocol Number: RM06/8013 Start Date*: 2007-04-05
    Sponsor Name:Leeds Teaching Hospital NHS Trust
    Full Title: An open study on the pharmacokinetics and safety of oral voriconazole in adult patients with cystic fibrosis
    Medical condition: Adult patients with cystic fibrosis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011762 Cystic fibrosis LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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