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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44381   clinical trials with a EudraCT protocol, of which   7393   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    10,987 result(s) found. Displaying page 182 of 550.
    «« First « Previous 178  179  180  181  182  183  184  185  186  Next» Last»»
    EudraCT Number: 2018-004019-34 Sponsor Protocol Number: ABI-H0731-211 Start Date*: 2019-02-20
    Sponsor Name:Assembly Biosciences
    Full Title: A Multi-center, Open-label, Long-term Extension Study of ABI-H0731 + Nucleos(t)ide as Finite Treatment for Chronic Hepatitis B Patients
    Medical condition: Chronic Hepatitis B
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2016-001049-24 Sponsor Protocol Number: ACW0002 Start Date*: 2017-04-03
    Sponsor Name:Actinogen Medical
    Full Title: XanADu: A Phase II, Double-Blind, 12-Week, Randomised, Placebo-Controlled Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in Subjects with Mild Dementia due to Alzheimer’s Disea...
    Medical condition: Mild Dementia due to Alzheimer’s Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10012271 Dementia Alzheimer's type PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020452-64 Sponsor Protocol Number: version2.0 Start Date*: 2010-10-05
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: A prospective randomisd open label study to determine the effects of intravenous iron administration on markers of acute kidney injury in chronic kidney disease (CKD)
    Medical condition: patients with known chonic kidney disease with functional or absolute Iron deficiency Anaemia, and are greater than 18 years will be given repleacement iron therapy accoring to current local protoc...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10005329 - Blood and lymphatic system disorders 10022973 Iron deficiency anaemias LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005295-32 Sponsor Protocol Number: TRALIS001 Start Date*: 2006-02-01
    Sponsor Name:Research and Development Department, Addenbrookes NHS Foundation Trust
    Full Title: Trial in rheumatoid arthritis of lisinopril (TRALIS)
    Medical condition: Rheumatoid arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-004974-16 Sponsor Protocol Number: IL1ra03 Start Date*: 2018-11-08
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
    Full Title: DOUBLE-BLIND PLACEBO-CONTROLLED RANDOMISED CLINICAL DOSE-RANGING STUDY TREATING MODERATE-SEVERE TRAUMATIC BRAIN INJURY PATIENTS WITH RECOMBINANT HUMAN INTERLEUKIN 1 RECEPTOR ANTAGONIST.
    Medical condition: We wish to study the drug Kineret in patients suffering from moderate-to-severe traumatic brain injury
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004863 10060690 Traumatic brain injury LLT
    20.1 10029205 - Nervous system disorders 10051288 Central nervous system inflammation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-004210-26 Sponsor Protocol Number: 14/0647 Start Date*: 2016-11-22
    Sponsor Name:PRIMENT Clinical Trials Unit, UCL
    Full Title: A Phase IV double blind multi-site, individually randomised parallel group controlled trial investigating the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in pati...
    Medical condition: Depression
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000024331 10066555 Chronic depression LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000982-38 Sponsor Protocol Number: 06/JM/119 Start Date*: 2007-06-14
    Sponsor Name:Greenpark Health Care Trust
    Full Title: Pain and mobility outcomes following patient controlled lumbar plexus block for primary joint arthroplasty
    Medical condition: Pain control after primary joint arthroplasty
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-001003-38 Sponsor Protocol Number: RGHT000540 Start Date*: 2008-08-01
    Sponsor Name:The Royal Group of Hospitals, Belfast Trust
    Full Title: A study investigating rimonabant versus placebo in conjunction with a strict low-fat weight reduction diet in overweight and obese subjects: effects on glucose and lipid metabolism and cardiovascul...
    Medical condition: This study will investigate subjects who are overweight and obese with Body Mass Index >27kg/m2.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022489 Insulin resistance LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-013133-22 Sponsor Protocol Number: RGHT 000669 Start Date*: 2009-07-31
    Sponsor Name:Belfast Health & Social Care Trust
    Full Title: Comparison of the effects of single shot or continuous popliteal nerve block on postoperative outcome measures in patients undergoing operative repair of ankle fracture.
    Medical condition: POSTOPERATIVE ANALGESIA AFTER OPERATIVE REPAIR OF ANKLE FRACTURE
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015840-40 Sponsor Protocol Number: LEVO/HK Start Date*: 2009-10-19
    Sponsor Name:Belfast Health and Social Care Trust
    Full Title: Chronic pain and mobility outcomes following primary hip arthroplasty. A comparison of intravenous morphine with lumbar plexus levobupivacaine.
    Medical condition: Acute and chronic pain following hip replacement surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-003835-30 Sponsor Protocol Number: Start Date*: 2005-05-26
    Sponsor Name:Belfast City Hospital
    Full Title: An open label, single centre, assessor blind pilot study comparing topical tacrolimus 0.1% and hydrocortisone ointment 1% in the treatment of flexural psoriasis
    Medical condition: flexural psoriasis
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-001780-40 Sponsor Protocol Number: 11069 Start Date*: 2015-05-21
    Sponsor Name:University of Oxford, Clinical Trials and Research Governance
    Full Title: A multi-centre, double blind, randomised, placebo-controlled, parallel group, phase II trial to determine the efficacy of intra-nodular injection of anti-TNF to control disease progression in early...
    Medical condition: Dupuytren's disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10013872 Dupuytren's contracture PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2014-004133-16 Sponsor Protocol Number: IH141 Start Date*: 2015-02-19
    Sponsor Name:Hull and east Yorkshire Hospitals Trust
    Full Title: Exploratory multicentre prospective double blinded randomised controlled pilot study of the effect of intravenous iron supplementation(Monofer)in iron deficient but not anaemic patients with Chroni...
    Medical condition: Chronic Kidney Disease stages 3b to 5 with iron deficiency
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-012097-12 Sponsor Protocol Number: TP103EU Start Date*: 2009-09-03
    Sponsor Name:CHUGAI PHARMA EUROPE LIMITED
    Full Title: Phase II, open-label, multi-centre study of TP300 as a single agent as first line therapy in patients with advanced gastric cancer or gastroeosophageal junction adenocarcinoma.
    Medical condition: Patients with advanced gastric cancer or gastroeosophageal junction (Types II & III) adenocarcinoma will be investigated. Patients will be given TP300 as a single agent as first line therapy admini...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10017758 Gastric cancer PT
    12.0 10001141 Adenocarcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2017-001739-38 Sponsor Protocol Number: TAK-831-2001 Start Date*: 2017-09-19
    Sponsor Name:Takeda Development Centre Europe Ltd.
    Full Title: A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Cross-Over Study to Evaluate Pharmacodynamic Effects, Safety, Tolerability, and pharmacokinetics of Multiple Oral Doses of TAK-831 in Adult...
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10039626 Schizophrenia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2018-003891-11 Sponsor Protocol Number: LMT-01-02-18 Start Date*: 2019-07-16
    Sponsor Name:Life Molecular Imaging SA
    Full Title: An Open Label, Single Center Study, to evaluate the Safety and Imaging Characteristics of [18F]PI-2620 as PET Radioligand for Imaging Tau deposition in the brains of subjects with amnestic mild cog...
    Medical condition: Alzheimer's Disease Amnestic Mild Cognitive Impairment
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10001897 Alzheimer's disease (incl subtypes) HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2005-000662-39 Sponsor Protocol Number: BMS2/05 Start Date*: 2005-10-04
    Sponsor Name:Oxford Brookes University
    Full Title: A 2x2 phase II randomized controlled trial to investigate the efficacy of NRT plus St John's wort versus NRT plus placebo in smoking cessation and to examine the efficacy of chromium nicotinate ve...
    Medical condition: Stopping smoking.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2008-002467-13 Sponsor Protocol Number: RRG8.46-RRG/3273/05-1 Start Date*: 2009-05-06
    Sponsor Name:Northern Health and Social Care Trust
    Full Title: A non-inferiority study of the clinical effectiveness of anaesthesia obtained via application of Topical Anaesthetic Gel compared to infiltration of lidocaine for the treatment of lacerations in th...
    Medical condition: Small to medium sized lacerations with no underlying nerve or other gross structural damage which would require further medical or surgical investigation.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023572 Laceration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020783-38 Sponsor Protocol Number: VB-201-030 Start Date*: 2010-09-29
    Sponsor Name:Vascular Biogenics Ltd
    Full Title: A Phase II, Randomised, Double blind, Placebo-Controlled, Dose-Ranging Study to Assess the Effect of Multiple Doses of VB-201 on Biomarkers of Inflammation, Safety and Pharmacokinetics in Subjects ...
    Medical condition: elevated hsCRP and other biomarkers for inflammation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-004822-26 Sponsor Protocol Number: SFPT/01 Start Date*: 2007-12-20
    Sponsor Name:Birmingham Children's Hospital
    Full Title: A randomised pilot trial of a steroid-free immunosuppressant regimen in paediatric liver transplantation
    Medical condition: Post isolated liver transplant complications
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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