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Clinical trials for Photodynamic therapy

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    The EU Clinical Trials Register currently displays   44343   clinical trials with a EudraCT protocol, of which   7372   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    20 result(s) found for: Photodynamic therapy. Displaying page 1 of 1.
    EudraCT Number: 2018-004685-33 Sponsor Protocol Number: NL67545 Start Date*: 2019-05-01
    Sponsor Name:azM
    Full Title: Surgical excision versus photodynamic therapy and topical 5-fluorouracil in treatment of Bowen’s disease: a multicenter randomized controlled trial
    Medical condition: Bowens's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2022-003913-12 Sponsor Protocol Number: 22/589-EC_M. Start Date*: 2023-03-07
    Sponsor Name:COMPLUTENSE UNIVERSITY OF MADRID
    Full Title: Diode laser and photodynamic therapy Versus Ciclopirox Hydroxypropyl Chitosan. Randomised controlled clinical trial.
    Medical condition: Onychomycosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005809-77 Sponsor Protocol Number: NL38217 Start Date*: 2013-01-31
    Sponsor Name:Maastricht University Medical Centre
    Full Title: Treatment of superficial basal cell carcinoma by topical photodynamic therapy with fractionated 5-aminolevulinic acid 20% versus two stage topical photodynamic therapy with methylaminolevulinate
    Medical condition: Superficial basal cell carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003416-31 Sponsor Protocol Number: FAEDV-2012-01 Start Date*: 2013-02-22
    Sponsor Name:Fundación Academia Española de Dermatología y Venereología
    Full Title: Multicenter, randomized, open clinical trial comparing three sessions of methyl-aminolevulinate 16% (Metvix®) photodynamic therapy versus a group without photodynamic therapy to treat onychomycosis.
    Medical condition: onychomycosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011897-14 Sponsor Protocol Number: CLIN904 CCM201 Start Date*: 2009-07-08
    Sponsor Name:STEBA BIOTECH
    Full Title: EVALUATION OF THE SAFETY AND EFFICACY OF WST11-MEDIATED VASCULAR TARGETED PHOTODYNAMIC THERAPY ON NON-RESECTABLE OR INOPERABLE CHOLANGIOCARCINOMA
    Medical condition: Non-resectable or inoperable cholangiocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008594 Cholangiocarcinoma non-resectable LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001468-34 Sponsor Protocol Number: HLS01/2008 Start Date*: 2008-11-20
    Sponsor Name:AZIENDA OSPEDALIERA L. SACCO (A.O. DI RILIEVO NAZIONALE)
    Full Title: Phase III clinical trial multicenter randomized for the evaluation of the safety and efficacy of the combined treatment of intravitreal triamcinolone and photodynamic therapy versus intravitreal Be...
    Medical condition: Choroideal neo-vascularization type RAP.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015919 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019714-24 Sponsor Protocol Number: 10.002 Start Date*: 2010-09-02
    Sponsor Name:Research & Development Department
    Full Title: A phase II, open label, single site light dose escalation trial of single dose Verteporfin Photodynamic Therapy (PDT) in primary soft tissue sarcoma
    Medical condition: Primary soft tissue sarcoma in the upper and lower limbs of adults.
    Disease: Version SOC Term Classification Code Term Level
    13 10061271 Malignant soft tissue neoplasm LLT
    13 10039491 Sarcoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-017435-18 Sponsor Protocol Number: CLIN905 MLT202 Start Date*: 2010-02-04
    Sponsor Name:Steba Biotech S.A.
    Full Title: A Phase IIa, Safety and Preliminary Effects Study of WST11 (Stakel®)-Mediated Vascular-Targeted Photodynamic (VTP) Therapy in Subjects with Choroidal Neovasularization (CNV) Associated with Age-Rel...
    Medical condition: Age associated Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064930 Age-related macular degeneration LLT
    12.1 10067791 Wet macular degeneration LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011895-31 Sponsor Protocol Number: CLIN903 LCM201 Start Date*: 2009-07-08
    Sponsor Name:STEBA BIOTECH
    Full Title: EVALUATION OF THE SAFETY AND EFFICACY OF WST11 MEDIATED VASCULAR TARGETED PHOTODYNAMIC THERAPY ON OBSTRUCTING ENDOBRONCHIAL NON-SMALL CELL LUNG CANCER
    Medical condition: Obstructive endobronchial non-small cell lung cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029514 Non-small cell lung cancer NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003134-13 Sponsor Protocol Number: A551109 Start Date*: 2012-02-13
    Sponsor Name:Erasmus MC
    Full Title: 5-Aminolevulinic Acid PhotoDynamic Therapy for the treatment of premalignant disorders of the vulva.
    Medical condition: Premalignant vulvar disorders (usual type Vulvar Intraepithelial Neoplasia)
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062135 Vulval neoplasm PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000110-37 Sponsor Protocol Number: PDT-DCF-1 Start Date*: 2013-03-18
    Sponsor Name:Fundacion para la investigación biomédica del hospital Ramón y Cajal de Madrid
    Full Title: Clinical effectiveness and effect on COX-2 expression of the sequential treatment of actinic keratoses (AK) with photodynamic therapy (PDT) and diclofenac 3% gel: a phase IV clinical trial.
    Medical condition: Actinic keratosis
    Disease: Version SOC Term Classification Code Term Level
    15.1 10040785 - Skin and subcutaneous tissue disorders 10000614 Actinic keratosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004119-11 Sponsor Protocol Number: SPECT Start Date*: 2016-12-19
    Sponsor Name:Leiden University Medical Center
    Full Title: Study on half-dose Photodynamic therapy versus Eplerenone in chronic CenTRAl serous chorioretinopathy (SPECTRA trial)
    Medical condition: Chronic central serous chorioretinopathy
    Disease: Version SOC Term Classification Code Term Level
    19.0 10015919 - Eye disorders 10063118 Chorioretinopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018399-25 Sponsor Protocol Number: MuSH_1.2 Start Date*: 2011-03-17
    Sponsor Name:Medizinische Universität Wien, Univ.Klinik für Zahn-,Mund-u.Kieferheilkunde,Klin.Abt.f.orale Chirurg
    Full Title: A randomized controlled trial: Photodynamic Treatment for the therapy of premalignant mucosal oral lesions.
    Medical condition: Leukoplakia and oral lichen ruber.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10062037 Leukoplakia LLT
    12.1 10062037 Leukoplakia PT
    12.1 10030983 Oral lichen planus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-001781-15 Sponsor Protocol Number: IOBA-04-2012 Start Date*: 2012-07-31
    Sponsor Name:IOBA, Universidad de Valladolid
    Full Title: Initial protocol setting for the treatment of choroidal neovascularization associated to myopia magna with intravitreal bevacizumab: 3 vs 1 (BENEMCOR.es study)
    Medical condition: choroidal neovascularization associated to myopia magna
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10060837 Choroidal neovascularization LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016748-38 Sponsor Protocol Number: MAL-REG_01 Start Date*: Information not available in EudraCT
    Sponsor Name:Free State of Bavaria rep. by the Univ. of Regensburg, rep. by the Regensburg Univ. Hospital
    Full Title: Prospective, randomized, placebo-controlled, monocentric, two-armed, observer-blinded and within-patient study for Photodynamic Therapy (PDT) with MAL in the treatment of actinic keratoses (AK) and...
    Medical condition: actinic keratoses and photoaged skin
    Disease: Version SOC Term Classification Code Term Level
    12.0 10000614 Actinic keratosis LLT
    12.0 10065944 Photodamaged skin LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004494-41 Sponsor Protocol Number: CLIN2001UCM301 Start Date*: 2021-06-11
    Sponsor Name:Steba Biotech, S.A.
    Full Title: Multicenter Phase 3 Pivotal Study to Evaluate the Safety and Efficacy of TOOKAD (padeliporfin) Vascular Targeted Photodynamic Therapy in the Treatment of Low Grade Upper Tract Urothelial Cancer
    Medical condition: Low Grade Upper Tract Urothelial Cancer
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10077840 Urothelial cancer of renal pelvis LLT
    20.0 100000004864 10046375 Ureter cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) DE (Trial now transitioned) IT (Trial now transitioned) AT (Trial now transitioned) ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012809-19 Sponsor Protocol Number: CLIN902 PCM203 Start Date*: 2009-07-15
    Sponsor Name:STEBA BIOTECH SA
    Full Title: VASCULAR-TARGETED PHOTODYNAMIC THERAPY USING WST11 IN PATIENTS WITH LOCALISED PROSTATE CANCER
    Medical condition: Localized prostate cancer
    Disease: Version SOC Term Classification Code Term Level
    9.1 10060862 Prostate cancer LLT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: FR (Ongoing) NL (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000944-82 Sponsor Protocol Number: MK-3475-966 Start Date*: 2020-03-05
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase 3 Randomized, Double Blind Study of Pembrolizumab Plus Gemcitabine/Cisplatin versus Placebo Plus Gemcitabine/Cisplatin as First-Line Therapy in Participants with Advanced and/or Unresectabl...
    Medical condition: Advanced and/or Unresectable Biliary Tract Carcinoma (Intrahepatic, Extrahepatic, or Gallbladder)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10004655 Biliary carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Trial now transitioned) IE (Trial now transitioned) ES (Ongoing) NL (Trial now transitioned) FR (Trial now transitioned) IT (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-004826-14 Sponsor Protocol Number: KHB-1802 Start Date*: 2019-01-09
    Sponsor Name:Chengdu Kanghong Biotechnology Co., Ltd.
    Full Title: A Multicenter, Double-Masked, Randomized, Dose-Ranging Trial to Evaluate the Efficacy and Safety of Conbercept Intravitreal Injection in Subjects with Neovascular Age related Macular Degeneration
    Medical condition: Neovascular Age Related Macular Degeneration
    Disease: Version SOC Term Classification Code Term Level
    20.1 10015919 - Eye disorders 10064930 Age-related macular degeneration PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) LV (Completed) CZ (Completed) SK (Prematurely Ended) DK (Prematurely Ended) BG (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004004-19 Sponsor Protocol Number: QBGJ398-301 Start Date*: 2020-02-13
    Sponsor Name:QED Therapeutics, Inc.
    Full Title: A Phase 3 Multicenter, Open-Label, Randomized, Controlled Study of Oral Infigratinib versus Gemcitabine with Cisplatin in Subjects with Advanced/Metastatic or Inoperable Cholangiocarcinoma with FGF...
    Medical condition: Cholangiocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10008593 Cholangiocarcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Prematurely Ended) BE (Completed) GB (GB - no longer in EU/EEA) PT (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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