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Clinical trials for General anesthesia

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    368 result(s) found for: General anesthesia. Displaying page 10 of 19.
    EudraCT Number: 2012-000839-54 Sponsor Protocol Number: SMi-MW-12 Start Date*: 2012-06-07
    Sponsor Name:Rigshospitalet
    Full Title: The effect of late naloxon-infusion on secondary hyperalgesia after a first degree burn injury
    Medical condition: Induced pain in volunteers
    Disease: Version SOC Term Classification Code Term Level
    14.1 10018065 - General disorders and administration site conditions 10033371 Pain PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017921-20 Sponsor Protocol Number: none Start Date*: 2010-09-16
    Sponsor Name:Univ. Klinik für Anästhesiologie
    Full Title: Influence of Gender on the Plasma-Effect site equilibration time of propofol anesthetic and Cisatracurium Besylate neuromuscular blocking agent. A pilot study.
    Medical condition: effect of Gender on Pharmacokinetics of Propofol and cisatracurium
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2020-004931-25 Sponsor Protocol Number: INDEX Start Date*: 2021-09-10
    Sponsor Name:Turku University Hospital
    Full Title: Intranasal dexmedetomidine pharmacokinetics on patients under general anesthesia
    Medical condition: Knee osteoarthritis Hip osteoarthritis
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004859 10020108 Hips osteoarthritis LLT
    21.1 100000004859 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-001135-20 Sponsor Protocol Number: Albumin Start Date*: 2015-04-28
    Sponsor Name:Södertälje sjukhus AB
    Full Title: Volume kinetics for 20% albumin in conscious and anaesthetized humans with and without inflammation.
    Medical condition: Healthy adult volunteers, healthy patients undergoing surgery under general anesthesia, and patients in a state of inflammation after having undergone surgery under general anaesthesia (within 24 h...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-000537-69 Sponsor Protocol Number: PROP2% Start Date*: 2015-09-21
    Sponsor Name:Universitair Ziekenhuis Brussel
    Full Title: Real time monitoring of blood propofol concentration
    Medical condition: - General anaesthesia - Pharmacokinetics and Pharmacodynamics of Propofol - Inflammatory parameters - Elective thyroid, oncologic breast,ENT or cervical arthrodesis surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2022-002892-12 Sponsor Protocol Number: CHUB-VASO-IRC Start Date*: 2022-09-13
    Sponsor Name:CHU Brugmann
    Full Title: Comparison of the efficacy of ephedrine versus norepinephrine in the treatment of hypotension occurring after induction of general anesthesia in patients with chronic renal failure: randomized doub...
    Medical condition: Hypotension occurring post-induction of general anesthesia in patients with chronic renal failure during elective surgery.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004857 10009119 Chronic renal failure LLT
    20.0 10047065 - Vascular disorders 10021097 Hypotension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2004-000369-37 Sponsor Protocol Number: NKT102245 Start Date*: 2005-02-01
    Sponsor Name:GlaxoSmithKline Group of Companies
    Full Title: A multicentre, randomised, double-blind, placebo-controlled, parallel group study to evaluate the safety and efficacy of oral dosing with GW679769 (50 mg or 150 mg) for 3 consecutive days in conjun...
    Medical condition: Post Operative Nausea and Vomiting (PONV) Post Discharge Nausea and Vomiting (PDNV)
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: HU (Completed) GB (Completed) ES (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2017-002009-37 Sponsor Protocol Number: 0517 Start Date*: 2017-07-14
    Sponsor Name:Neuroanæstesiologisk Klinik, RH/Glostrup
    Full Title: "The effect of Betamethasone gel and NSAID gel lubricated on the laryngeal mask on pain in the throat, hoarseness and cough after anesthesia. "
    Medical condition: 'Healthy volunteers' (sore throat, hoarseness and cough, consumption of analgesics, postoperative itching, numbness and burning sensation from the throat)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10022891 Investigations SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-000232-15 Sponsor Protocol Number: HIDROGEL-014 Start Date*: 2016-07-13
    Sponsor Name:Consorcio Hospital General Universitario de Valencia . Servicio de Anestesia , Reanimacion y tto del Dolor
    Full Title: Analgesic efficacy of levobupivacaine administered by wet wound dressing for the management split-thickness skin graft donor sites
    Medical condition: acute postoperative pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005179-25 Sponsor Protocol Number: 402-C-326 Start Date*: 2016-06-10
    Sponsor Name:Pacira Pharmaceuticals, Inc.
    Full Title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block with EXPAREL for Postsurgical Analgesia in Subjects Un...
    Medical condition: Total Knee Arthroplasty
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004865 10038286 Regional nerve block LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DK (Completed)
    Trial results: View results
    EudraCT Number: 2007-002314-19 Sponsor Protocol Number: meduniwien_lma_lido_3 Start Date*: 2007-10-19
    Sponsor Name:Medical University of Vienna, Department of Anesthesiology
    Full Title: Larynxmaske bei Kindern nach Atemwegsinfekt: Der Effekt topischer Anästhesie mit Lidocain Effect of Lidocain-gel for laryngeal mask lubrification in pediatric patients after acute respiratory disease
    Medical condition: Acute respiratory diseases are common in pediatric patients scheduled for general anesthesia, and can cause perioperative problems up to 6 weeks after the acute respiratory infection. In the prese...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038700 Respiratory infection LLT
    Population Age: Children, Under 18 Gender: Male
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-004833-25 Sponsor Protocol Number: UNLOCK Start Date*: 2017-03-29
    Sponsor Name:Consorci Mar Parc de Salut de Barcelona (Parc de Salut Mar)
    Full Title: Synchronous effect of anesthetics on fMRI, EEG and clinical responses. Development of a more precise system for monitoring anesthetic effect.
    Medical condition: General anaesthesia in healthy subjects
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-004920-40 Sponsor Protocol Number: AFFECT Start Date*: 2021-03-22
    Sponsor Name:Vestre Viken HF
    Full Title: Affective effects of pre-surgery opioids (AFFECT): a randomized double-blind controlled trial
    Medical condition: Healthy adult surgery patients. Health status ASA1 or ASA2 as categorised by a medical doctor at the hospital based on medical history, physical examination. The American Society of Anesthesiologis...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006006-27 Sponsor Protocol Number: 0869-219 Start Date*: 2012-11-05
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc
    Full Title: A Phase IIb, Partially-Blinded, Randomized, Active Comparator-Controlled Study to Evaluate the Pharmacokinetics/Pharmacodynamics, Safety, and Tolerability of Aprepitant in Pediatric Patients for th...
    Medical condition: Post Operative Nausea and Vomiting in surgical patients
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10036901 Prophylaxis against postoperative nausea and vomiting LLT
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: HU (Completed) ES (Completed) CZ (Completed) IT (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2017-001122-17 Sponsor Protocol Number: ISRCTN12771155 Start Date*: 2017-11-13
    Sponsor Name:SILVIA GONZALEZ SANTOS
    Full Title: "ANALGESIC EFFICACY OF INTRADURAL MORPHINE VERSUS INTERCOSTAL LEVOBUPIVACAINE IN THE POSTOPERATIVE PERIOD OF MAJOR PULMONARY RESECTION BY VIDEOTHORASCOCOPY"
    Medical condition: Control of the pain in surgery of major resection for videotoracoscopia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-000663-83 Sponsor Protocol Number: SM3-ME-13 Start Date*: 2013-04-19
    Sponsor Name:Rigshospitalet
    Full Title: The effect of Adductor-Channel Blockade with high pain responders after reconstruction of the anterior cruciate ligament
    Medical condition: Patients who will undergo reconstruktion of ligament cruciate ligament.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004865 10036236 Postoperative pain relief LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-005086-55 Sponsor Protocol Number: 2008/PAEDAN/01 Start Date*: 2008-11-18
    Sponsor Name:NHS Greater Glasgow & Clyde and University of Glasgow
    Full Title: Evaluation of propofol TCI anaesthesia in infants age 6m-3y.
    Medical condition: Children undergoing general anaesthesia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021722 Induction and maintenance anaesthesia LLT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-002848-25 Sponsor Protocol Number: CN145-010 Start Date*: 2006-02-28
    Sponsor Name:Bristol-Myers Squibb SL
    Full Title: Protocol Title: A Phase IV, Multi-Center, Randomized, Double-Blind, Placebo- Controlled Study to Evaluate The Analgesic Efficacy And Safety of IV Paracetamol Versus Placebo in subjects with postope...
    Medical condition: Pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2020-001215-24 Sponsor Protocol Number: 7-190320 Start Date*: 2020-05-12
    Sponsor Name:Aarhus University Hospital
    Full Title: The effect of subpectineal obturator nerve block on opioid consumption and pain after hip arthroscopy A double-blind randomized, controlled trial
    Medical condition: Postoperative pain after hip arthroscopy
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004848 10080604 Hip arthroscopy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-000164-93 Sponsor Protocol Number: 1000000 Start Date*: 2006-05-10
    Sponsor Name:Department of Anesthesiology University Hospital Center
    Full Title: Effect of Nutritional Support on Liver Integrity during General Anesthesia for Laparoscopic Cholecystectomy. A Pilot Study
    Medical condition: To the best of our knowledge, there is no clinical study on the protective effect of nutritional support on the liver in the perioperative setting using clinical and biological variables. Regarding...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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