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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44338   clinical trials with a EudraCT protocol, of which   7368   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,338 result(s) found. Displaying page 1,093 of 2,217.
    EudraCT Number: 2017-005093-19 Sponsor Protocol Number: AT251-G-17-005 Start Date*: 2019-01-08
    Sponsor Name:Akros Pharma Inc.
    Full Title: A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JTT-251 Administered for 24 Weeks to Participants with Heart Failure with Reduced E...
    Medical condition: Heart Failure with Reduced Ejection Fraction (HFrEF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10078289 Heart failure with reduced ejection fraction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) HU (Completed) DK (Prematurely Ended) NL (Completed)
    Trial results: View results
    EudraCT Number: 2021-001266-38 Sponsor Protocol Number: C3291027 Start Date*: 2021-06-09
    Sponsor Name:Pfizer Inc
    Full Title: A PHASE 3, MULTICENTER, OPEN-LABEL STUDY OF THE LONG-TERM SAFETY OF CRISABOROLE OINTMENT, 2% IN JAPANESE PEDIATRIC AND ADULT PARTICIPANTS WITH MILD TO MODERATE ATOPIC DERMATITIS
    Medical condition: Atopic dermatitis
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2014-000296-12 Sponsor Protocol Number: T13/2014 Start Date*: 2014-04-15
    Sponsor Name:Turku University Hospital
    Full Title:
    Medical condition: Multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029205 - Nervous system disorders 10028245 Multiple sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2015-001962-25 Sponsor Protocol Number: BR1-142 Start Date*: 2016-03-04
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: A Prospective Multicenter Phase III Clinical Evaluation of the Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress Echocardiography with Dobutamine for the Diagnosis ...
    Medical condition: Suspected or known Coronary Artery Disease
    Disease: Version SOC Term Classification Code Term Level
    18.0 10007541 - Cardiac disorders 10011082 Coronary artery disorders HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2013-004626-28 Sponsor Protocol Number: T214/2013 Start Date*: 2013-12-20
    Sponsor Name:Turku University Hospital
    Full Title: Does targeting of S1P receptors reduce microglial activation in multiple sclerosis?
    Medical condition: Multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10028245 Multiple sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: View results
    EudraCT Number: 2013-004204-19 Sponsor Protocol Number: 2013-827 Start Date*: 2014-02-26
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Efficacité du bevacizumab en spray nasal pour le traitement des épistaxis dans la maladie de Rendu-Osler
    Medical condition: Rendu-Osler disease
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004850 10031132 Osler-Weber-Rendu disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2015-005303-91 Sponsor Protocol Number: VIT_D_2015 Start Date*: 2016-07-04
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Full Title: Clinical Trial of pharmacokinetics of calcifediol (25OHD3) in women with postmenopausal osteoporosis
    Medical condition: postmenopausal osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    20.0 10027433 - Metabolism and nutrition disorders 10013296 Bone, calcium, magnesium and phosphorus metabolism disorders HLGT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2021-000364-30 Sponsor Protocol Number: I4T-MC-JVDA Start Date*: 2021-06-01
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 1 Study Of Ramucirumab, a Human Monoclonal Antibody Against the Vascular Endothelial Growth Factor-2 (VEGFR-2) Receptor in Children With Refractory Solid Tumors, Including CNS Tumors
    Medical condition: Pediatric Solid Tumor CNS Malignancies
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2008-005354-20 Sponsor Protocol Number: 12710A Start Date*: 2016-03-15
    Sponsor Name:H. Lundbeck A/S
    Full Title: Interventional, randomised, double-blind, placebo-controlled, active reference (fluoxetine), fixed-dose study of vortioxetine in paediatric patients aged 12 to 17 years, with Major depressive disor...
    Medical condition: Major Depressive Disorder
    Disease: Version SOC Term Classification Code Term Level
    19.1 10037175 - Psychiatric disorders 10057840 Major depression PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LV (Completed) EE (Completed) GB (Completed) HU (Completed) BG (Completed) DE (Completed) FI (Not Authorised) IT (Completed) ES (Completed) BE (Completed) PL (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2020-005515-51 Sponsor Protocol Number: 202000814 Start Date*: 2021-06-28
    Sponsor Name:Medical University Medical Center Groningen
    Full Title: An explorative and feasibility study of Venetoclax combined with Tamoxifen in patients with relapsed/refractory Diffuse Large B-cell Lymphoma
    Medical condition: relapsed/refractory Diffuse Large B-cell Lymphoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019225-33 Sponsor Protocol Number: 31630 Start Date*: 2010-05-18
    Sponsor Name:
    Full Title: A Randomized Phase II Study Of Reirradiation And Hyperthermia Versus Reirradiation And Hyperthermia Plus Chemotherapy For Locally Recurrent Breast Cancer In Previously Irradiated Area
    Medical condition: All patients with a local regional recurrence of invasive breast cancer in previously irradiated area with measurable lesions not suitable for resection are eligible for this trial. Patients with m...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10008456 Chemotherapy single agent systemic LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003789-25 Sponsor Protocol Number: mela1 Start Date*: 2015-02-26
    Sponsor Name:Department of surgery, Herlev Hospital
    Full Title: The anxiolytic effects of melatonin: A randomized, placebo-controlled, double-blinded clinical study.
    Medical condition: We intend to investigate the anxiolytic effects of melatonin in relation to surgery.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10002855 Anxiety PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-009928-37 Sponsor Protocol Number: CONKO-008 Start Date*: 2009-10-21
    Sponsor Name:Charite Universitätsmedizin Berlin
    Full Title: Phase 1/2 Studie: CONKO-008 Oxaliplatin/Folinsäure/5-Fluorouracil (24h) in Kombination mit Lapatinib in der Zweitlinientherapie des Pankreaskarzinoms nach Progress unter Gemcitabin-Monotherapie
    Medical condition: Pancreatic cancer patients who failed first line therapy with gemcitabine
    Disease: Version SOC Term Classification Code Term Level
    9.1 10033604 Pancreatic cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2011-000035-89 Sponsor Protocol Number: Start Date*: 2011-02-16
    Sponsor Name:Med. Univ. Wien, Klinik für klinische Pharmakologie
    Full Title: Target site pharmacokinetics of doripenem at steady state in intubated intensive care patients
    Medical condition: We will carry out the present study to determine concentrations of doripenem in plasma, in the interstitial space fluid of the subcutaneous and muscle tissue and ELF in 20 intubated intensive care ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2016-000393-37 Sponsor Protocol Number: RA0134 Start Date*: 2016-08-08
    Sponsor Name:UCB Biopharma Sprl
    Full Title: A MULTICENTER, SUBJECT-BLIND, INVESTIGATOR-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY EVALUATING THE EFFICACY, SAFETY/TOLERABILITY, AND PHARMACOKINETICS OF MULTIPLE INTRAVENOUS DOSES OF BIMEKIZUMA...
    Medical condition: RHEUMATOID ARTHRITIS
    Disease: Version SOC Term Classification Code Term Level
    19.0 10028395 - Musculoskeletal and connective tissue disorders 10039073 Rheumatoid arthritis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: View results
    EudraCT Number: 2011-004518-40 Sponsor Protocol Number: PCV13-HIV2011 Start Date*: 2011-10-25
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: Serological response to antipneumococcal vaccination and consequent impact on Streptococcus pneumoniae nasal carriage in HIV positive adults: a prospective study using 13-valent conjugate vaccine
    Medical condition: HIV positive adults with out previous PPV23 or PCV7 vaccination
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10035652 Pneumococcus infection in conditions classified elsewhere and of unspecified site LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-002124-27 Sponsor Protocol Number: Exa-Bone_1 Start Date*: 2014-10-28
    Sponsor Name:Endocrine Research Unit, Odense University Hospital
    Full Title: GLP-1 Agonist and Bone: Effects of Exenatide on Bone Metabolism
    Medical condition: bone metabolism
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004848 10067225 Biochemical markers of bone metabolism HLT
    Population Age: Elderly Gender: Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000216-28 Sponsor Protocol Number: KIMIII Start Date*: 2013-01-14
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Innere Medizin III
    Full Title: Treat-To-Target Trial of Continuous Subcutaneous , sensor-augmented insulin-pump therapy in new-onset diabetes after transplantation (SAPT-NODAT): Efficacy and Safety of an Intensive Insulin Protoc...
    Medical condition: New onset diabetes after organ-transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-002780-82 Sponsor Protocol Number: 63513 Start Date*: 2005-07-20
    Sponsor Name:Richter Gedeon Rt
    Full Title: Alendronat (Sedron 70 mg) hatékonyságának és biztonságosságának nyílt, multicentrikus, fázis IV vizsgálata osteoporosisban szenvedő veseköves férfibetegekben
    Medical condition: osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    8.0 10031282 PT
    Population Age: Adults Gender: Male
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2017-000234-57 Sponsor Protocol Number: allo-APZ2-DFU-II-01 Start Date*: 2017-08-07
    Sponsor Name:RHEACELL GmbH & Co. KG
    Full Title: An interventional, multicenter, single arm, phase I/IIa clinical trial to investigate the efficacy and safety of allo-APZ2-DFU on wound healing of diabetic neuropathic ulcer (DFU).
    Medical condition: Diabetic neuropathic ulcer (DFU)
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10012664 Diabetic foot ulcer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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