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Clinical trials for System

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    9,808 result(s) found for: System. Displaying page 111 of 491.
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    EudraCT Number: 2015-000244-42 Sponsor Protocol Number: acid_permeability_healthyvolunteers Start Date*: 2015-04-21
    Sponsor Name:KU Leuven
    Full Title: The role of mast cells on duodenal permeability after duodenal acid perfusion in healthy volunteers
    Medical condition: To investigate the role of mast cells on duodenal permeability after duodenal acid perfusion. The study will be done in healthy volunteers and the results will give an indication about the role of ...
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004856 10064536 Functional dyspepsia LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2009-010708-28 Sponsor Protocol Number: none02 Start Date*: 2009-07-03
    Sponsor Name:Department of Anaesthesia
    Full Title: Does the stellate ganglion block improve postoperative analgesia following upper limb trauma?
    Medical condition: We propose that the sympathetic nervous system contributes to acute pain and that a sympathetic nerve block, the stellate ganglion block, will improve postoperative pain in patients presenting for ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10054711 Postoperative pain LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-003396-20 Sponsor Protocol Number: MMUH-Conway01 Start Date*: 2012-11-26
    Sponsor Name:Cardiothoracic Surgery, Mater Misericordiae University Hospital
    Full Title: Is the optimal dose of preoperative statin associated with decreased end organ injury and better clinical outcome post cardiopulmonary bypass?
    Medical condition: Patient listed for open heart surgery involving cardiopulmonary bypass.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-003337-15 Sponsor Protocol Number: CLR_18_06 Start Date*: 2019-06-18
    Sponsor Name:Sun Pharma Advanced Research Company (SPARC) Limited
    Full Title: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of K0706 in Subjects With Early Parkinson’s Disease
    Medical condition: Early Parkinson’s Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10061536 Parkinson's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Prematurely Ended) SK (Completed) ES (Ongoing)
    Trial results: View results
    EudraCT Number: 2013-001199-39 Sponsor Protocol Number: MulticenterEbastineIBS Start Date*: 2013-11-21
    Sponsor Name:KULeuven
    Full Title: Histamine 1 receptor antagonist ebastine as novel treatment in IBS
    Medical condition: Patients who suffer from irritable bowel syndrome which are diarrhea predominant and mixed (alteration of constipation and diarrhea)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-000228-24 Sponsor Protocol Number: MANA2016-1 Start Date*: 2016-07-13
    Sponsor Name:UZ Brussel
    Full Title: Eradication of H. pylori infection in Belgium: bismuth versus first line therapy
    Medical condition: Patients with H. pylori infection, never treated before
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2021-004057-23 Sponsor Protocol Number: 2021-12945 Start Date*: 2022-02-28
    Sponsor Name:Radboudumc
    Full Title: Ethanol submandibular duct ligation for drooling in children with neurodisabilities
    Medical condition: Drooling or sialorrhea
    Disease:
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2020-002307-18 Sponsor Protocol Number: 2020-002307-18 Start Date*: 2021-02-10
    Sponsor Name:Oslo University Hospital
    Full Title: A phase IIa, double-blind, randomised, placebo-controlled study on the efficacy and tolerability of a 14-day treatment with teriflunomide 14 mg tablets vs. placebo in subjects with well-controlled ...
    Medical condition: Coeliac disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10009839 Coeliac disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000105-65 Sponsor Protocol Number: 1 Start Date*: 2006-08-30
    Sponsor Name:Medical University of Vienna, Department of Internal Med. I, Division of Infectious Diseases
    Full Title: Comparative study of the efficacy and tolerance of intravenously administered azithromycin (1.5 g) given either as a single dose or over a 3 day period in patients with community-acquired pneumonia
    Medical condition: community aquired pneumonia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002180-33 Sponsor Protocol Number: SMderpept Start Date*: 2016-11-16
    Sponsor Name:Centrum Neurologii Krzysztof Selmaj
    Full Title: Multiple sclerosis therapy with transdermal myelin peptide stimulation.
    Medical condition: relapsing-remitting multiple sclerosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: PL (Completed)
    Trial results: (No results available)
    EudraCT Number: 2025-000121-13 Sponsor Protocol Number: ZP4207-21052 Start Date*: 2025-05-21
    Sponsor Name:Zealand Pharma A/S
    Full Title: A Phase 3, single-administration, open-label trial to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of dasiglucagon when administered as a rescue therapy for severe hypoglycem...
    Medical condition: Severe hypoglycemia in Type 1 Diabetes (T1D) patients
    Disease:
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2018-002295-40 Sponsor Protocol Number: 08-06-2018-paracet Start Date*: 2018-09-11
    Sponsor Name:Copenhagen Neuromuscular Center
    Full Title: Pharmacokinetics and safety of treatment with paracetamol in children and adults with spinal muscular atrophy and cerebral palsy
    Medical condition: Spinal muscular atrophy type II (SMA II) Cerebral palsy (CP)
    Disease:
    Population Age: Children, Under 18, Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-002175-34 Sponsor Protocol Number: EPOCH Start Date*: 2012-10-23
    Sponsor Name:Med. Univ. Wien, Universitätsklinik f. Innere Medizin III, Abt. f. Nephrologie und Dialyse
    Full Title: Eplerenone on Top of ACE Inhibition in Chronic Kidney Disease Patients with Hypertension (EPOCH)
    Medical condition: proteinuric patients suffering from chronic kidney disease (II - III) ,diabetes mellitus II and hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2014-004282-25 Sponsor Protocol Number: CHUBX2014/10 Start Date*: 2015-03-25
    Sponsor Name:CHU de Bordeaux
    Full Title: Subcutaneous route and pharmacology of metoclopramide - SOPHA-Méto
    Medical condition: Digestive disorder (Nausea and vomiting) in palliative care and oncology
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2019-003151-11 Sponsor Protocol Number: CNTO1275UCO2001 Start Date*: 2020-05-08
    Sponsor Name:UZ Leuven
    Full Title: Stelara fOr ChRonic AntibioTic rEfractory pouchitiS (SOCRATES): A Belgian open label multicenter pilot-study
    Medical condition: Chronic antibiotic refractory and relapsing pouchitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2019-004600-35 Sponsor Protocol Number: 70880 Start Date*: 2020-02-25
    Sponsor Name:Department of Hepatology and Gastroenterology, Aarhus University Hospital
    Full Title: Fat-reduced diet vs. bile acid binder as a treatment for bile acid malabsorption in patients with chronic diarrhoea as a late side effect after cancer treatment in the pelvic region - a randomised,...
    Medical condition: Bile acid malabsorption as a late side effect to cancer treatment in the pelvic region.
    Disease: Version SOC Term Classification Code Term Level
    20.1 100000004856 10080051 Bile acid diarrhoea LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003133-42 Sponsor Protocol Number: 1672_2019 Start Date*: 2020-02-14
    Sponsor Name:Medical University of Vienna, Department of Ophthalmology and Optometry
    Full Title: Personalized treatment aided by automated analysis of fluid in active neovascular age-related macular degeneration (nAMD) in a prospective, multicenter, randomized study
    Medical condition: Nevoascular age related macular degneration (nAMD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Trial now transitioned)
    Trial results: View results
    EudraCT Number: 2021-002629-95 Sponsor Protocol Number: 170188 Start Date*: 2022-08-02
    Sponsor Name:Department of vascular surgery, Lillebaelt Hospital
    Full Title: Cefuroxime and Piperacillin Concentrations in the Biliary System
    Medical condition: Infection in the biliary system such as cholecystitis and cholangitis both as acute infections and post-operative infections.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004871 10008618 Cholecystitis chronic NOS LLT
    20.0 100000004871 10008615 Cholecystitis acute NOS LLT
    20.0 100000004871 10008619 Cholecystitis NOS LLT
    20.0 100000004871 10004638 Bile duct stone with cholecystitis LLT
    20.0 100000004871 10007004 Calculus of gallbladder with acute cholecystitis LLT
    20.0 100000004871 10006995 Calculus of bile duct with acute cholecystitis LLT
    20.0 100000004871 10008606 Cholangitis acute NOS LLT
    20.0 100000004871 10008608 Cholangitis NOS LLT
    20.0 100000004871 10008607 Cholangitis chronic NOS LLT
    20.1 100000004862 10056952 Septic cholangitis LLT
    23.0 100000004862 10083504 Acute obstructive suppurative cholangitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2021-006788-11 Sponsor Protocol Number: NBI-827104-CSWS2025 Start Date*: 2022-03-25
    Sponsor Name:Neurocrine Biosciences, Inc.
    Full Title: Long-Term, Open-Label Extension Study to Evaluate the Safety and Tolerability of NBI-827104 in Pediatric Subjects with Epileptic Encephalopathy with Continuous Spike-and-Wave During Sleep
    Medical condition: Epileptic Encephalopathy with Continuous Spike-and-Wave During Sleep (EECSWS)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10077380 Epileptic encephalopathy PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed) ES (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2020-005340-39 Sponsor Protocol Number: S64807 Start Date*: 2021-02-01
    Sponsor Name:University Hospitals Leuven
    Full Title: Duodenal neuro-immune interactions and effects of proton pump inhibitors in functional dyspepsia
    Medical condition: Functional Dyspepsia (FD)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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