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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 1,139 of 2,219.
    «« First « Previous 1135  1136  1137  1138  1139  1140  1141  1142  1143  Next» Last»»
    EudraCT Number: 2005-004468-22 Sponsor Protocol Number: HEAD-STUDIE Start Date*: 2006-03-31
    Sponsor Name:Klinikum der Universität München, Kinderklinik und Poliklinik im Dr. von Haunerschen Kinderspital
    Full Title: HEAD-TO-HEAD evaluation of the antiepileptic drugs Levetiracetam (LEV) vs. Sulthiame (STM) in a German multi-centre, doubleblind controlled trial in children with benign epilepsy with centro-tempor...
    Medical condition: Benign epilepsy of childhood with centro-temporal spikes (BECTS)
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-003742-16 Sponsor Protocol Number: IB1001-04 Start Date*: 2014-04-29
    Sponsor Name:Cangene Europe Limited
    Full Title: Pharmacokinetics, Safety and Efficacy of Recombinant Factor IX Product, IB1001, in Patients with Severe Hemophilia B
    Medical condition: Severe Hemophilia B
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004850 10018939 Haemophilia B (Factor IX) LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005299-32 Sponsor Protocol Number: OPHT-110912 Start Date*: 2013-01-24
    Sponsor Name:Medizinische Universität Wien, Universitätsklinik für Klinische Pharmakologie
    Full Title: Effect of breathing 100% oxygen on brain metabolites measured by 7-Tesla MRI
    Medical condition: brain metabolism
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022891 - Investigations 10033316 Oxygen saturation PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-004898-16 Sponsor Protocol Number: V_1 Start Date*: 2015-05-27
    Sponsor Name:Medizinische Universität Wien
    Full Title: A study to investigate (R)-11C-verapamil PET as a predictive biomarker for epilepsy surgery outcome
    Medical condition: temporal lobe epilepsy
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029205 - Nervous system disorders 10043209 Temporal lobe epilepsy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-005895-34 Sponsor Protocol Number: VER1.0 Start Date*: 2006-06-05
    Sponsor Name:Department of Clinical Pharmacology, Medical University of Vienna
    Full Title: Effects of common topical glaucoma therapy on optic nerve head blood flow autoregulation during increased arterial blood pressure and artificially elevated intraocular pressure in healthy humans
    Medical condition: only healthy volunteers are included
    Disease:
    Population Age: Adults Gender: Male
    Trial protocol: AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-004463-69 Sponsor Protocol Number: RadiRet Start Date*: 2012-12-11
    Sponsor Name:Charité – University Medicine Berlin
    Full Title: Investigation of Radiation Retinopathy (RadiRet Study) Subtitle: Influence of Lucentis® on radiation retinopathy after irradiation of choroidal melanoma
    Medical condition: Patients with retinopathy, due to irradiation in uveal melanoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10022117 - Injury, poisoning and procedural complications 10064714 Radiation retinopathy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-003943-32 Sponsor Protocol Number: DORO001 Start Date*: 2015-08-06
    Sponsor Name:Charité University Medicine Berlin
    Full Title: Influence of diabetes control on treatment of diabetic macular edema with ranibizumab
    Medical condition: Diabetic macular edema
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004853 10057934 Diabetic macular edema LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-001027-20 Sponsor Protocol Number: CACZ885GDE01T Start Date*: 2012-04-03
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: A Multi-Centre, Placebo-Controlled Phase II Study of Canakinumab for the Treatment of Adult-onset Still's disease (AOSD) including an open-label long term extension.
    Medical condition: adult onset Still's disease (AOSD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10028395 - Musculoskeletal and connective tissue disorders 10042061 Still's disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-006126-10 Sponsor Protocol Number: Efalizumab in CTCL Start Date*: 2008-11-27
    Sponsor Name:Charité - University Hospital Berlin
    Full Title: pilot study to evaluate the efficacy of Efalizumab in patients with cutaneous t-cell lymphoma
    Medical condition: The cutaneous T-cell lymphoma (also known as Sézary syndrome) is a common disorder of proliferated cells with characteristics of maligne t-lymphocytes immigrating from the cutaneous blood vessels t...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2011-000844-56 Sponsor Protocol Number: TOPAS2011 Start Date*: 2011-07-12
    Sponsor Name:Charité Universitätsmedizin Berlin
    Full Title: UsTekinumab for the treatment Of Patients with active Ankylosing Spondylitis (TOPAS) – a 28-week, prospective, open-label, proof-of-concept study
    Medical condition: Ankylosing spondylitis
    Disease: Version SOC Term Classification Code Term Level
    13.1 10028395 - Musculoskeletal and connective tissue disorders 10002556 Ankylosing spondylitis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-004466-26 Sponsor Protocol Number: G1T28-04 Start Date*: 2017-07-10
    Sponsor Name:G1 Therapeutics
    Full Title: Phase 2 Study of the Safety, Efficacy, and Pharmacokinetics of G1T28 in Patients with Metastatic Triple Negative Breast Cancer Receiving Gemcitabine and Carboplatin Chemotherapy
    Medical condition: Locally recurrent or metastatic Triple Negative Breast Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10075566 Triple negative breast cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) SI (Completed) HR (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2020-003168-22 Sponsor Protocol Number: 2020/0206/HP Start Date*: 2021-09-02
    Sponsor Name:Rouen University Hospital
    Full Title: Multicenter, uncontrolled pilot study evaluating the efficacy of eculizumab in the treatment of gemcitabine-induced thrombotic microangiopathies.
    Medical condition: Thrombotic microangiopathies induced by gemcitabine
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10043645 Thrombotic microangiopathy PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007011-85 Sponsor Protocol Number: 13578 Start Date*: 2009-12-10
    Sponsor Name:Charite Universitätsmedizin Berlin
    Full Title: Topical application of morphine for wound healing and analgesia in patients with painful oral lesions
    Medical condition: Erosive and/or ulcerative Oral Lichen Planus.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-000963-42 Sponsor Protocol Number: GB29298 Start Date*: 2014-10-01
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: A randomized, double-blind, placebo-controlled, phase II study to assess the efficacy and safety of oral vismodegib for the treatment of idiopathic pulmonary fibrosis
    Medical condition: Idiopathic pulmonary fibrosis
    Disease: Version SOC Term Classification Code Term Level
    17.0 10038738 - Respiratory, thoracic and mediastinal disorders 10021240 Idiopathic pulmonary fibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-000248-91 Sponsor Protocol Number: BTACH2012 Start Date*: 2013-01-08
    Sponsor Name:Institutt for nevromedisin, NTNU
    Full Title: Endoscopic block of the sphenopalatine ganglion with botulinum toxin in intractable cluster headache. Safety issues.
    Medical condition: Pharmacological refractory cluster headache with durations of periods of attacks normally more than 2 months
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004852 10009698 Cluster headaches LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NO (Completed)
    Trial results: View results
    EudraCT Number: 2008-002143-16 Sponsor Protocol Number: CUV023 Start Date*: 2010-02-04
    Sponsor Name:Clinuvel Pharmaceuticals Limited
    Full Title: A Phase III, multicentre, double–blind, placebo controlled, cross over study to evaluate the safety and efficacy of subcutaneous bioresorbable implants of afamelanotide in the treatment of solar ur...
    Medical condition: Solar urticaria (SU)
    Disease: Version SOC Term Classification Code Term Level
    12.0 10041307 Solar urticaria LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-001581-42 Sponsor Protocol Number: 17972A Start Date*: 2018-11-19
    Sponsor Name:H. Lunbeck A/S
    Full Title: Interventional, randomized, double-blind, parallel-group, placebo-controlled, fixed-flexible-dose study of Lu AF11167 for the treatment of persistent prominent negative symptoms in patients with sc...
    Medical condition: schizophrenia with persistent prominent negative symptoms
    Disease: Version SOC Term Classification Code Term Level
    20.0 10037175 - Psychiatric disorders 10039626 Schizophrenia PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: EE (Prematurely Ended) LV (Prematurely Ended) HU (Completed) BG (Prematurely Ended) PL (Completed) CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-010843-15 Sponsor Protocol Number: CUV026 Start Date*: 2009-10-09
    Sponsor Name:Clinuvel Pharmaceuticals Limited
    Full Title: A Phase III, randomised, double blind, placebo controlled study to evaluate the safety and efficacy of subcutaneous implants of afamelanotide (16 mg) in patients suffering from polymorphic light er...
    Medical condition: Polymorphic light eruption (PLE)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10036087 Polymorphic light eruption PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-023790-19 Sponsor Protocol Number: Monofer-ISS-Blooddonor-01 Start Date*: 2011-08-29
    Sponsor Name:Rigshospitalet, afd. 2034
    Full Title: Et randomiseret, prospektivt, dobbeltblindt, komparativt, placebokontrolleret forsøg med intravenøs indgift af jernisomaltosid 1000 (Monofer®) via infusioner til bloddonorer med jernmangel
    Medical condition: Forsøg med intravenøs indgift af jernisomaltosid 1000 (Monofer®) via infusioner til bloddonorer med jernmangel. Dobbelblindet, placebokontrolleret forsøg.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10005329 - Blood and lymphatic system disorders 10022974 Iron deficiency anemia LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-004370-34 Sponsor Protocol Number: POM-003 Start Date*: 2018-04-09
    Sponsor Name:Amicus Therapeutics, Inc.
    Full Title: A Prospective Study in Subjects with Late-onset Pompe Disease who are Currently Being Treated with Enzyme Replacement Therapy
    Medical condition: Late-onset Pompe disease (LOPD) in subjects receiving standard-of-care enzyme replacement therapy (ERT)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004850 10075702 Pompe's disease late onset LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Prematurely Ended) HU (Prematurely Ended)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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