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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    8,950 result(s) found. Displaying page 127 of 448.
    «« First « Previous 123  124  125  126  127  128  129  130  131  Next» Last»»
    EudraCT Number: 2014-001675-32 Sponsor Protocol Number: ARTE Start Date*: 2014-10-20
    Sponsor Name:IUCPQ
    Full Title: Aspirin versus Aspirin + ClopidogRel as Antithrombotic Treatment Following Transcatheter Aortic Valve Implantation with the Edwards Valve. A Randomized Study (the ARTE trial).
    Medical condition: Incidence of death, MI, ischemic stroke/Transient ischemic attack (TIA) or life threatening/major bleeding at 3-month follow-up.
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004849 10013118 Diseases of aortic valve LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-005310-35 Sponsor Protocol Number: AD-03-013 Start Date*: 2014-08-13
    Sponsor Name:Fundación para la Investigación en Enfermedades del Aparato Digestivo
    Full Title: A phase IV double-blind, randomized, placebo-controlled, multi-center study with pancreatic enzyme replacement therapy (PERT) in subjects suffering from pancreatic exocrine insufficiency (PEI) afte...
    Medical condition: Patients 2 weeks after discharge from the hospital after an attack of acute necrotizing pancreatitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002044-41 Sponsor Protocol Number: 38RC14.176 Start Date*: 2014-08-18
    Sponsor Name:University Hospital of Grenoble
    Full Title:
    Medical condition:
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003610-86 Sponsor Protocol Number: EMCD1403 Start Date*: 2014-11-14
    Sponsor Name:
    Full Title: A double blind randomized controlled trial comparing the efficacy of 7% lidocaine / 7% tetracaine cream versus 2,5% lidocaine / 2,5% prilocaine cream for local anaesthesia during laser treatment of...
    Medical condition: Pain during laser treatment of: 1. Tattoo 2. Acne keloidalis nuchae
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004799-50 Sponsor Protocol Number: PNEUMOREG Start Date*: 2015-02-13
    Sponsor Name:Federico Martinon Torres
    Full Title: Evaluation of the immunoregulatory role of pneumococcal conjugate vaccination in pediatric patients with allergic asthma or type 1 diabetes mellitus versus pediatric population control.
    Medical condition: Allergic asthma and type 1 diabetes mellitus in pediatric subjects.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-003631-36 Sponsor Protocol Number: RG_12-124 Start Date*: 2015-02-10
    Sponsor Name:University of Birmingham
    Full Title: CALiBRe: Assessment of the Mechanism of Action of idelalisib (CAL-101) in B-cell Receptor Pathway Inhibition in CLL
    Medical condition: Chronic lymphocytic leukaemia
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004864 10068852 B-cell chronic lymphocytic leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2013-001226-25 Sponsor Protocol Number: HD-TNBC-TRIAL Start Date*: 2015-04-20
    Sponsor Name:ISTITUTI OSPITALIERI DI CREMONA
    Full Title: A phase II randomized, open-label neo-adjuvant study of standard chemotherapy regimen compared to high dose chemotherapy regimen with autologous stem cell transplantation in patients with triple ne...
    Medical condition: Triple Negative Breast Cancer patients with breast tumor >2,5 cm
    Disease: Version SOC Term Classification Code Term Level
    17.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006187 Breast cancer PT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005786-23 Sponsor Protocol Number: XCEL-SCI-01 Start Date*: 2016-04-20
    Sponsor Name:Banc de Sang i Teixits
    Full Title: A phase I/IIa, randomized, double-blind, single-dose, placebo controlled, two-way crossover clinical trial to assess the safety and to obtain efficacy data in intrathecal administration of expanded...
    Medical condition: Chronic traumatic spinal cord injury
    Disease: Version SOC Term Classification Code Term Level
    18.1 10022117 - Injury, poisoning and procedural complications 10041558 Spinal cord injury thoracic PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-004414-28 Sponsor Protocol Number: BLASTO-01-2014 Start Date*: 2015-06-10
    Sponsor Name:Hospital Universitari Mutua Terrassa
    Full Title: Controlled, randomized trial, comparing the efficacy of paromomicin and cotrimoxazol versus metronidazol in the eradication of Blastocystis hominis in patients with gastrointestinal symptoms.
    Medical condition: Gastrointestinal symptoms by Blastocystis hominis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-002445-31 Sponsor Protocol Number: SIMBA-16 Start Date*: 2017-01-20
    Sponsor Name:Enrique de Madaria
    Full Title: SIMBA trial: Simvastatin in the Prevention of Recurrent Acute Pancreatitis, a Triple Blind Randomized Controlled Trial
    Medical condition: Recurrent acute pancreatitis (RAP)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10017947 - Gastrointestinal disorders 10033647 Pancreatitis acute PT
    20.0 10017947 - Gastrointestinal disorders 10033657 Pancreatitis relapsing PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-001876-31 Sponsor Protocol Number: SWAP Start Date*: 2016-10-26
    Sponsor Name:King's College London [...]
    1. King's College London
    2. Guy's and St Thomas NHS Foundation Trust
    Full Title: Feasibility of the safe withdrawal of inhaled corticosteroids in patients with mild to moderate COPD prescribed outside guidelines (SWAP)
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10009033 Chronic obstructive pulmonary disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2015-002836-42 Sponsor Protocol Number: PRUEI Start Date*: 2017-06-22
    Sponsor Name:Asociación Instituto de Investigación Sanitaria BioCruces
    Full Title: Phase II Pilot Study to assess security, potential feasibility and effectiveness of treatment with platelet rich plasma in vascular ulcers iwth difficult healing in lower extremities.
    Medical condition: Ulcer that does not heal after being administered the optimal basic care after a period of six weeks.
    Disease: Version SOC Term Classification Code Term Level
    19.1 10040785 - Skin and subcutaneous tissue disorders 10050502 Neuropathic ulcer PT
    19.1 10040785 - Skin and subcutaneous tissue disorders 10012679 Diabetic neuropathic ulcer PT
    19.1 10040785 - Skin and subcutaneous tissue disorders 10040796 Skin and subcutaneous tissue ulcerations HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004137-91 Sponsor Protocol Number: Gesida92016 Start Date*: 2018-01-23
    Sponsor Name:Fundacion SEIMC-GESIDA
    Full Title: A single-arm, open-label, multicenter phase IV trial to evaluate the efficacy and safety of elvitegravir / cobicistat / emtricitabine / tenofovir alfa-namide as first-line treatment in naïve patien...
    Medical condition: AIDS
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10001509 AIDS LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002355-28 Sponsor Protocol Number: PAP_RI1_2017/12 Start Date*: 2018-07-12
    Sponsor Name:CHU of Pointe-A-Pitre
    Full Title: Impact of high dose of cholecalciferol in critically ill septic patients with vitamin D deficiency: the CaribDean study
    Medical condition: Morbi-mortality in critically ill patients is linked to vitamin D deficiency. Moreover, vitamin D deficiency has been related to inappropriate response to infection (due to vitamin D involvement in...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-003009-40 Sponsor Protocol Number: CCR4326 Start Date*: 2015-12-18
    Sponsor Name:Royal Marsden NHS Foundation Trust
    Full Title: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker to Stratify Management of Good And Poor Responders To Chemoradiotherapy: A Rectal Cancer Multicentre Randomised Control Trial
    Medical condition: Rectal cancer
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10061758 Chemotherapy PT
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
    18.0 10042613 - Surgical and medical procedures 10068093 Gastrointestinal surgery PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2017-004983-37 Sponsor Protocol Number: FFIS-INM-2017-04 Start Date*: 2018-10-16
    Sponsor Name:Fundación para la Formación e Investigación Sanitarias de la Región de Murcia
    Full Title: Multicenter, randomized, prospective study to establish the clinical efficacy and the mechanisms of tolerance following immunosuppression withdrawal in liver transplantation
    Medical condition: Hepatic transplant
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004299-24 Sponsor Protocol Number: 1.0 Start Date*: 2017-11-02
    Sponsor Name:Erasmus MC Kanker Instituut
    Full Title: Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk score - a feasibility study
    Medical condition: Patients with resectable colorectal liver metastases
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-001143-12 Sponsor Protocol Number: 11-EI-0264 Start Date*: 2018-01-09
    Sponsor Name:The National Eye Institute
    Full Title: A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein Occlusions
    Medical condition: Central Retinal Vein Occlusion
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2016-003413-10 Sponsor Protocol Number: ACDHUVV-16 Start Date*: 2016-12-20
    Sponsor Name:FIMABIS
    Full Title: MicroRNAs expression analysis in patients undergoing cardiac surgery treated with halogenated anesthetics. Identification of microRNAs related to the cardioprotective effect
    Medical condition: Cardiac surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-002764-94 Sponsor Protocol Number: OZBS82.17204 Start Date*: 2019-07-29
    Sponsor Name:Erasmus MC
    Full Title: Adjuvant vaccination against HPV in surgical treatment of CIN lesions, a Randomised Controlled Trial
    Medical condition: Human papilloma virus (HPV) causes cervical cancer. HPV vaccination is highly effective in primary prevention. There is less known about a possible secondary effect in women already infected with H...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10028986 Neoplasm cervix LLT
    20.0 100000004865 10046859 Vaccination LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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