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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44347   clinical trials with a EudraCT protocol, of which   7375   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    9,051 result(s) found. Displaying page 127 of 453.
    «« First « Previous 123  124  125  126  127  128  129  130  131  Next» Last»»
    EudraCT Number: 2008-006716-38 Sponsor Protocol Number: 0816002 Start Date*: 2009-05-11
    Sponsor Name:CHU de Toulouse
    Full Title: Etude observationnelle des évènements indésirables graves survenant chez les patients traités par rituximab pour maladie dysimmunitaire hors polyarthrite rhumatoïde .
    Medical condition: maladies dysimmunitaires hors polyarthrite rhumatoîde
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061664 Autoimmune disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005206-39 Sponsor Protocol Number: deferiprone08 Start Date*: 2008-10-13
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALI GALLIERA
    Full Title: Pilot Study: Iron-chelating treatment in patients with Neurodegeneration with Brain Iron Accumulation (NBIA).
    Medical condition: patients with NBIA
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 Nervous system disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-005212-40 Sponsor Protocol Number: MR080508 Start Date*: 2008-10-14
    Sponsor Name:Karolinska Institute
    Full Title: Pain mechanisms and fatigue in rheumatoid arthritis (RA) and healthy volunteers. Can antirheumatic and biological therapy affect pain processing and fatigue in RA?
    Medical condition: Rheumatoid arthritis (RA) The overall aim with this project is to investigate central pain mechanisms in RA and healthy controls, and in RA how these are influenced by autonomic neural regulation ...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039073 Rheumatoid arthritis LLT
    9.1 10060016 Alpha tumor necrosis factor LLT
    9.1 10029817 Nuclear magnetic resonance imaging brain LLT
    9.1 10053689 Cardiovascular autonomic function test LLT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001081-80 Sponsor Protocol Number: NL22172 Start Date*: 2008-06-20
    Sponsor Name:Leiden University Medical Center
    Full Title: Relevance of Biomarkers and Clinical Predictors of Outcome in Unselected Population with Febrile Urinary Tract Infection at Primary Care and Emergency Department in a Prospective, Randomized Cohort...
    Medical condition: To determine whether a 7-day duration of antibiotic treatment is non inferior to 14-day standard duration of treatment in adults presenting at primary care or emergency department with febrile uri...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-005985-10 Sponsor Protocol Number: PTF-REN-001 Start Date*: 2008-03-03
    Sponsor Name:Juan Francisco Navarro González
    Full Title: Análisis del Efecto Renoprotector de la Pentoxifilina en Pacientes con Enfermedad Renal Crónica Secundaria a Nefropatía Diabética
    Medical condition: Enfermedad renal crónica secundaria a nefropatía diabética.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061835 Diabetic nephropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-002378-68 Sponsor Protocol Number: SIRES Start Date*: 2007-10-30
    Sponsor Name:SERVICIO NEFROLOGIA HOSPITAL BELLVITGE
    Full Title: Estudio piloto de Selección de la Inmunosupresión basado en un régimen basado en inhibidores de CNI o libre de CNI dependiendo de la aloreactividad donante-especifica mediante el ensayo ELISPOT en ...
    Medical condition: PATIENTS THAT RECEIVE A FIRST RENAL ALLOGRAFT TRANSPLANTATION. It has been shown that the assessment of the donor specific T-cell alloimmune response can be successfully performed by using new too...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023438 Kidney transplant LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003636-30 Sponsor Protocol Number: LMS2006 Start Date*: 2008-04-16
    Sponsor Name:Karolinska University Hospital
    Full Title: Effect of continuous versus cyclic dosing regimen of hormonal contraception on bleeding pattern, cardivascular risk marker, sexual function and satisfaction
    Medical condition: The study aims to evaluate the bleeding pattern, side-effects, cardiovascular riskmarker, sexual function and user-satisfaction when combined contraceptive hormonal methods are being administered c...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010808 Contraception LLT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004231-38 Sponsor Protocol Number: 08-BO-VIBH Start Date*: 2009-01-26
    Sponsor Name:Department of Medicine I, University Hospital St.Josef-Hospital, Ruhr University Bochum
    Full Title: Effects of vildagliptin (Galvus®) on beta-cell function and turnover in humans
    Medical condition: Diabetes mellitus, beta-cell function before and after pancreatic surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10012601 Diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004285-53 Sponsor Protocol Number: VA 2008/28 Start Date*: 2008-12-19
    Sponsor Name:Centre Régional de Lutte contre le Cancer Val d'Aurelle- Paul Lamarque
    Full Title: Etude de phase I-II évaluant l’association Sorafénib (NEXAVAR®) et Irinotecan en deuxième ligne ou plus de traitement des cancers colorectaux métastatiques avec une mutation de Kras – NEXIRI
    Medical condition: Cancer du côlon ou du rectum métastatique prouvé histologiquement
    Disease: Version SOC Term Classification Code Term Level
    9.1 10052358 Colorectal cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-000885-21 Sponsor Protocol Number: BETA Start Date*: 2008-03-25
    Sponsor Name:TNO
    Full Title: The effect of betahistine 48 mg three times daily on motion sickness
    Medical condition: This study will evaluate the impact of betahistine on motion sickness.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027990 Motion sickness LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007650-35 Sponsor Protocol Number: GOTEL/09-01 Start Date*: 2009-04-02
    Sponsor Name:GOTEL (Grupo Oncológico para el Tratamiento de las Enfermedades Linfoides)
    Full Title: Estudio Fase II abierto prospectivo no aleatorizado para valorar la combinación de rituximab, bendamustina (R-B) en pacientes con Linfoma Folicular refractarios o en recaída tras tratamiento con R...
    Medical condition: Linfoma Folicular refractarios o en recaída tras tratamiento con R-quimioterapia en primera línea
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016762-87 Sponsor Protocol Number: early transition Start Date*: 2006-03-24
    Sponsor Name:OSPEDALE MAGGIORE DI MILANO (IRCCS)
    Full Title: a randomized, open-label study to evaluate the safety and efficacy of delayed introduction of sirolimus and concomitant tacrolimus elimination in de novo renal allograft recipients
    Medical condition: no
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038359 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011289-27 Sponsor Protocol Number: CF001 Start Date*: 2009-04-22
    Sponsor Name:UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
    Full Title: Probiotics in Cystic Fibrosis
    Medical condition: Cystic Fibrosis Patients
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017947 SOC
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012370-12 Sponsor Protocol Number: 09/3-W Start Date*: 2009-10-30
    Sponsor Name:CHU Nantes
    Full Title: Pharmacocinétique de l’ertapénème chez des patients brûlés sous ventilation mécanique. Étude monocentrique de médicament, de phase IV, ouverte, prospective.
    Medical condition: Grands brûlés (30 à 60% de la surface corporelle)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10022117 Injury, poisoning and procedural complications SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012372-27 Sponsor Protocol Number: 200901 Start Date*: 2009-09-17
    Sponsor Name:LUMC
    Full Title: The Sevoflurane study, understanding the effects of Sevoflurane to improve safety and outcome of cardiac surgery
    Medical condition: myocardial ischemia reperfusion injury during cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10017501 Functional disturbances following cardiac surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011156-21 Sponsor Protocol Number: CCFM 119/209 Start Date*: 2011-04-28
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: Effects of beta-blockers on exercise performance in uncomplicated hypertension
    Medical condition: Non complicated arterial hypertension
    Disease: Version SOC Term Classification Code Term Level
    14.0 10047065 - Vascular disorders 10015488 Essential hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013547-11 Sponsor Protocol Number: 09-059 Start Date*: 2009-07-16
    Sponsor Name:Leids Universitair Medisch Centrum
    Full Title: Sodium Bicarbonate for the prevention of Contrast Induced Nephropathy in patients undergoing CTPA
    Medical condition: The prevention of Contrast Induced Nephropathy is under investigation. Contrast induced nephropathy (CIN) can occur after injecting radiographic iso osmolair contrast media. Patients with a renal i...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10037790 Radiocontrast nephropathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014892-31 Sponsor Protocol Number: MAIVECMOPAIN Start Date*: 2009-11-10
    Sponsor Name:ErasmusMC - Sophia
    Full Title: Morphine intravenous vs. Paracetamol intravenous in children on ECMO
    Medical condition: Patients treated with Extra Corporal Membrane Oxygenation (ECMO) receive morphine as standardised analgesic drug. Morphine is associated with several side effects. In these patients a non-opioid dr...
    Disease:
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-012300-69 Sponsor Protocol Number: Number 1 Start Date*: 2010-03-26
    Sponsor Name:Meander Medisch Centrum
    Full Title: Does vitamin D deficiency contribute to fatigue in patients in remission after treatment of gynaecological malignancy?
    Medical condition: Vitamin D deficiency in patients in complete remission after successful treatment of a gynaecological malignancy.
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018992-16 Sponsor Protocol Number: PI10 - Pr. Dupont Start Date*: 2010-12-30
    Sponsor Name:Centre hospitalier universitaire d'Amiens
    Full Title: Evaluation pharmacocinétique de MDZ028 après administration unique d'une forme orale nouvelle, lors de la prémédication anesthésique chez l'enfant.
    Medical condition: prémédication anesthésique
    Disease: Version SOC Term Classification Code Term Level
    12.1 10058073 Anaesthetic premedication LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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