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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44346   clinical trials with a EudraCT protocol, of which   7374   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,346 result(s) found. Displaying page 1,386 of 2,218.
    EudraCT Number: 2014-003878-16 Sponsor Protocol Number: B7391003 Start Date*: 2015-05-27
    Sponsor Name:Pfizer Inc, 235 East 42nd Street, New York, NY 10017
    Full Title: A Phase 3 randomized, double-blind study of PF-06439535 plus Paclitaxel-Carboplatin and Bevacizumab plus Paclitaxel-Carboplatin for the first-line treatment of patients with advanced non-squamous n...
    Medical condition: Advanced non-squamous non-small cell lung cancer.
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) NL (Completed) CZ (Completed) DE (Completed) ES (Completed) PL (Completed) HU (Completed) GR (Completed) HR (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2015-005134-21 Sponsor Protocol Number: HP-3070-GL-04 Start Date*: 2016-07-01
    Sponsor Name:Noven Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Fixed-Dose, 6-Week, In-Patient Study to Assess Efficacy and Safety of HP-3070 in Subjects Diagnosed with Schizophrenia
    Medical condition: Schizophrenia
    Disease: Version SOC Term Classification Code Term Level
    18.1 10037175 - Psychiatric disorders 10039626 Schizophrenia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: View results
    EudraCT Number: 2013-000508-40 Sponsor Protocol Number: 2819-CL-0202 Start Date*: 2014-11-18
    Sponsor Name:Astellas Pharma Europe B.V.
    Full Title: A Phase 3, Multicenter, Investigator-blind, Randomized, Parallel Group Study to Investigate the Safety and Efficacy of Fidaxomicin Oral Suspension or Tablets Taken q12h, and Vancomycin Oral Liquid ...
    Medical condition: Treatment of enterocolitis caused by Clostridium difficile
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004862 10012734 Diarrhea, Clostridium difficile LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) SK (Completed) PL (Completed) IT (Completed) ES (Completed) HU (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2014-000583-18 Sponsor Protocol Number: 1160.108 Start Date*: 2014-07-25
    Sponsor Name:Boehringer Ingelheim España, S.A.
    Full Title: Open label, single arm safety prospective cohort study of dabigatran etexilate for secondary prevention of venous thromboembolism in children from 0 to less than 18 years
    Medical condition: Secondary prevention of venous thromboembolism
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004865 10049909 Venous thromboembolism prophylaxis LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) FI (Completed) AT (Completed) GR (Completed) IT (Completed) LT (Completed) CZ (Completed) BE (Completed) SK (Completed) SE (Temporarily Halted) BG (Completed) FR (Completed) HU (Completed) DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-003791-23 Sponsor Protocol Number: I4T-MC-JVDB Start Date*: 2015-04-23
    Sponsor Name:Eli Lilly and Company
    Full Title: Protocol I4T-MC-JVDB Randomized Phase 2 Trial Evaluating Pharmacokinetics and Safety of Four Ramucirumab Dosing Regimens in Second Line Gastric or Gastroesophageal Junction Adenocarcinoma
    Medical condition: Second Line Gastric or Gastroesophageal Junction Adenocarcinoma
    Disease: Version SOC Term Classification Code Term Level
    18.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10063916 Metastatic gastric cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) SK (Completed) FR (Completed) PL (Completed) RO (Completed)
    Trial results: View results
    EudraCT Number: 2006-002022-29 Sponsor Protocol Number: MV20145 Start Date*: 2006-07-27
    Sponsor Name:Karolinska Institutet, Center for Molecular medicine, L8:03 L8:03
    Full Title: A randomized double blind controlled proof of concept study of the efficacy and safety of Valcyte® as an add-on therapy in patients with malignant glioblastoma with successful surgical resection of...
    Medical condition: Malignant Glioblastoma with CMV infection demonstrated histologically and immunohistochemically
    Disease: Version SOC Term Classification Code Term Level
    8.1 10018336 Glioblastoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-004545-34 Sponsor Protocol Number: AT10001 Start Date*: 2006-02-20
    Sponsor Name:Unit of Esophageal and Gastric Research Dep. of Molecular Medicine and Surgery Karolinska Institutet
    Full Title: Can Angiotensin II type 1 Receptor Inhibitor Be Used to Lower the Amount of Lipase and Amylase Level after Endoscopic Retrograde Cholangio-Pancreatography?
    Medical condition: The clinical diagnosis of acute pancreatitis is set by a combination of symptoms (abdominal pain) and increased blood levels of pancreatic enzymes (i.e. amylase and lipase). The most common complic...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-002608-33 Sponsor Protocol Number: KI CLINTEC mikro 02 Start Date*: 2006-10-27
    Sponsor Name:Karolinska Institute, CLINTEC, div of orthopedics
    Full Title: En dubbelblind placebokontrollerad studie för utvärdering av postoperativa analgetikaeffekter via mikrodialys synovialt på patienter som genomgår artroskopi.
    Medical condition: Painfull knee condition of traumatic or other origin, where arthroscopic surgery is indicated, as judged by the surgeon.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002757-31 Sponsor Protocol Number: CLAF237A 2303E1 Start Date*: 2004-12-16
    Sponsor Name:Novartis Sverige AB
    Full Title: A 28-Week Extension to a Multicenter, Double-Blind, Randomized, Parallel-Group Study to Compare the Effect of 24 Weeks Treatment with LAF237 (50 mg qd or bid) to Placebo as Add-On Therapy in Patien...
    Medical condition: Type 2 Dibetes
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2006-003485-33 Sponsor Protocol Number: F1J-MC-HMFG Start Date*: 2007-03-21
    Sponsor Name:Eli Lilly and Company Limited
    Full Title: Duloxetine 60 to 120 mg versus Placebo in the Treatment of Patients with Osteoarthritis Knee Pain
    Medical condition: Osteoarthritis Knee Pain
    Disease: Version SOC Term Classification Code Term Level
    8.1 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2006-007031-27 Sponsor Protocol Number: INS-001 Start Date*: 2007-04-17
    Sponsor Name:Karolinska Institute
    Full Title: Effects of insulin treatment on postprandial platelet activation in patients with NIDDM: a placebo-controlled dose-response study with insulin aspart (Novorapid®)
    Medical condition: Patients with type 2 diabetes mellitus below 70 years of age and without a history of cardiovascular disease.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-003186-40 Sponsor Protocol Number: DM-ASA 001 Start Date*: 2007-09-05
    Sponsor Name:Karolinska Institute
    Full Title: Evaluation of antiplatelet effects of different dosages of aspirin in type 2 diabetic patients.
    Medical condition: Patients with type 2 diabetes mellitus with an indication for aspirin treatment or already on aspirin treatment.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007519-34 Sponsor Protocol Number: FAST VERSION Start Date*: 2009-04-17
    Sponsor Name:University of Leuven Hospitals, Division of Gastroenterology
    Full Title: Feasibility of Accelerated infliximab infusions - Safety and Tolerability in patients wit IBD. FAST
    Medical condition: This is a open label, prospective, multicenter trial in patients recieving one hour infusions of infliximab (i.e. Remicade)as part of their daily practice. Main objective: Is to assess the tolerab...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-000922-31 Sponsor Protocol Number: Cognitivefunction2011001 Start Date*: 2011-04-18
    Sponsor Name:Karolinska Institutet
    Full Title: Patients´ recovery day 0-3 after short-stay elective surgery – a pilot study comparing desflurane and propofol TCI as main anaesthetics.
    Medical condition: Patients undergoing elective general anaesthesia for breat surgery
    Disease: Version SOC Term Classification Code Term Level
    12.1 10002091 Anaesthesia LLT
    Population Age: Adults Gender: Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-002233-19 Sponsor Protocol Number: ASA-CABG-01 Start Date*: 2011-10-14
    Sponsor Name:Karolinska Institute
    Full Title: Antiplatelet effects of once versus twice daily dosing of aspirin after coronary artery bypass grafting
    Medical condition: Patients having successfully undergone coronary artery bypass graft (CABG) surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2005-005918-20 Sponsor Protocol Number: ITP001 Start Date*: 2008-12-23
    Sponsor Name:Rikshospitalet
    Full Title: Rituximab as second line treatment for ITP: A Multicentre, Randomized, Double blind, Placebo-controlled, Phase III study. “The RITP study”
    Medical condition: Immune thrombocytopenic purpura (ITP)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10021245 Idiopathic thrombocytopenic purpura LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) SE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-019214-25 Sponsor Protocol Number: AXP-CT-001 Start Date*: 2010-08-24
    Sponsor Name:Axcentua Pharmaceuticals AB
    Full Title: Safety, pharmacokinetics and efficacy of AXP107-11 in combination with standard gemcitabine (Gemzar®) treatment in patients with locally advanced or metastatic, unresectable, adenocarcinoma of the ...
    Medical condition: Histologically confirmed, unresectable, locally advanced or metastatic pancreatic cancer stage III-IV
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004864 10033606 Pancreatic cancer non-resectable LLT
    16.0 100000004864 10033605 Pancreatic cancer metastatic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2011-006206-27 Sponsor Protocol Number: Gra-geneticver1 Start Date*: 2012-02-21
    Sponsor Name:Karolinska Institutet
    Full Title: Does 5-HT polymorphism contribute to pain regulation and efficacy of granisetron?
    Medical condition: Experimentally induced muscle pain in healthy volunteers, both sexes and over 18 years of age.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004416-22 Sponsor Protocol Number: DMK001 Start Date*: 2005-01-05
    Sponsor Name:Karolinska Institutet, Dept of Medicine, Clinical Pharmacology Unit
    Full Title: Platelet function in diabetic patients without and with renal impairment, and the effects of lipid-lowering treatment
    Medical condition: Diabetes mellitus type 2, without or with renal impairment
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2013-000026-57 Sponsor Protocol Number: Gra-sensv1 Start Date*: 2013-07-19
    Sponsor Name:Karolinska Institutet
    Full Title: Effect of granisetron on facial skin sensitivity in healthy volunteers
    Medical condition: Healthy and pain-free volunteers > 20 years of age, both sexes
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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