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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44394   clinical trials with a EudraCT protocol, of which   7406   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,394 result(s) found. Displaying page 1,409 of 2,220.
    «« First « Previous 1405  1406  1407  1408  1409  1410  1411  1412  1413  Next» Last»»
    EudraCT Number: 2018-004019-34 Sponsor Protocol Number: ABI-H0731-211 Start Date*: 2019-02-20
    Sponsor Name:Assembly Biosciences
    Full Title: A Multi-center, Open-label, Long-term Extension Study of ABI-H0731 + Nucleos(t)ide as Finite Treatment for Chronic Hepatitis B Patients
    Medical condition: Chronic Hepatitis B
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: View results
    EudraCT Number: 2007-003756-11 Sponsor Protocol Number: MU0728 Start Date*: 2008-06-17
    Sponsor Name:Ardeypharm GmbH
    Full Title: Behandlung der Darm-assoziierten Halitosis mit E. coli Stamm Nissle 1917 Treatment for GUT-Caused Halitosis With with E. coli strain Nissle 1917
    Medical condition: gut-caused halitosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019058 Halitosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005344-15 Sponsor Protocol Number: BOTC3-OAB-01 Start Date*: 2013-03-25
    Sponsor Name:Adyton, s.r.o.
    Full Title: A Double Blind Study Aiming To Evaluate The Efficacy Of Bladder Instillation With Botulinum Toxin (200U) + TC-3 Gel In Comparison To Instillation With Botulinum Toxin (200U) + TC-3 Gel + DMSO, To D...
    Medical condition: Overactive bladder (OAB) syndrome (in women), as defined by the International Continence Society (ICS): severe urgency with or without urge urinary incontinence, usually accompanied with increased ...
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004857 10059617 Overactive bladder LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2013-001619-62 Sponsor Protocol Number: 12EU/Ct06 Start Date*: 2014-02-10
    Sponsor Name:IBSA, Institut Biochimique S.A.
    Full Title: A multicentre, comparative, randomised, double-blind, double-dummy clinical trial on the efficacy and safety of Condrosulf® versus Celebrex® and versus a placebo in the treatment of knee osteoarthr...
    Medical condition: knee osteoarthritisi, the most common form of arthritis and a leading cause of morbidity and disability
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) BE (Completed) CZ (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2016-001352-21 Sponsor Protocol Number: ABT-C5-2016 Start Date*: 2016-09-19
    Sponsor Name:Ability Pharmaceuticals, SL
    Full Title: A phase I/ II, open label study to assess the efficacy and safety of ABTL0812 in combination with paclitaxel and carboplatin in patients with advanced endometrial cancer or squamous NSCLC
    Medical condition: Squamous Cell Non-Small Cell Lung Cancer and advanced endometrial cancer
    Disease: Version SOC Term Classification Code Term Level
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014743 Endometrial carcinoma LLT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025120 Lung squamous cell carcinoma recurrent PT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10071533 Lung squamous cell carcinoma metastatic PT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014747 Endometrial carcinoma recurrent LLT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025124 Lung squamous cell carcinoma stage III PT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014745 Endometrial carcinoma metastatic LLT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014749 Endometrial carcinoma stage II LLT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014751 Endometrial carcinoma stage IV LLT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025125 Lung squamous cell carcinoma stage IV PT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10014750 Endometrial carcinoma stage III LLT
    19.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025126 Lung squamous cell carcinoma stage unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-000982-19 Sponsor Protocol Number: IOBA-ImmunEyez_011-2018 Start Date*: 2019-12-11
    Sponsor Name:Instituto de Oftalmobiología Aplicada (IOBA)
    Full Title: A Phase IV Open-Label Clinical Trial to Evaluate the Efficacy of Ikervis® on Clinical Parameters and Molecular/Cellular Biomarkers in Dry Eye Patients with Severe Keratitis who have not improved de...
    Medical condition: Dry eye disease with severe keratitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002510-13 Sponsor Protocol Number: TROMBOFIBtrial Start Date*: 2018-09-28
    Sponsor Name:Antoni Sabaté Pes (Servicio de Anestesiología y Reanimación) del Hospital Universitari de Bellvitge
    Full Title: Impact of two thrombelastography-guided strategies of fibrinogen correction on blood product requirements in liver transplantation: a multicenter, randomized trial. TROMBOFIB trial
    Medical condition: Liver transplantation is a special risk situation for acute and severe bleeding determined by the complexity of the surgical procedure and by the alteration of haemostasis and coagulation factors, ...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10024716 Liver transplantation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-004860-23 Sponsor Protocol Number: REACTIC2019-HAC Start Date*: 2020-05-22
    Sponsor Name:Andres Iñiguez Romo
    Full Title: REACTIC-TAVI TRIAL: Platelet REACtivity according to TICagrelor dose after Trancathter Aortic Valve Implantation. A pilot study.
    Medical condition: Patients with severe aortic stenosis submitted for Transcatheter Aortic Valve Implantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001342-18 Sponsor Protocol Number: IB-0319-001 Start Date*: 2019-08-19
    Sponsor Name:Instituto Bernabeu
    Full Title: CONVENTIONAL STIMULATION IN FOLICULAR PHASE VS. STIMULATION IN LUTEA PHASE IN PATIENTS WITH SUBOPTIMA RESPONSE. RANDOMIZED CLINICAL TRIAL. SUBLUTEAL STUDY
    Medical condition: Suboptimal response of ovarian stimulation
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-001573-78 Sponsor Protocol Number: 87RI20_0012 Start Date*: 2020-05-06
    Sponsor Name:RevImmune
    Full Title: Recombinant InterLeukin-7 (CYT107) to Improve clinical outcomes in lymphopenic pAtients with COVID-19 infection
    Medical condition: SARSCo-V-2
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001049-24 Sponsor Protocol Number: ACW0002 Start Date*: 2017-04-03
    Sponsor Name:Actinogen Medical
    Full Title: XanADu: A Phase II, Double-Blind, 12-Week, Randomised, Placebo-Controlled Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in Subjects with Mild Dementia due to Alzheimer’s Disea...
    Medical condition: Mild Dementia due to Alzheimer’s Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029205 - Nervous system disorders 10012271 Dementia Alzheimer's type PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2016-000631-40 Sponsor Protocol Number: T3inj-01 Start Date*: 2016-04-04
    Sponsor Name:Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.
    Full Title: Triiodothyronine for repair of left ventricular dysfunction and Remodeling in STEMI Patients
    Medical condition: Patients with anterior or anterolateral STEMI subjected to primary PCI.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064346 STEMI LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
    EudraCT Number: 2014-000354-11 Sponsor Protocol Number: ABR47613 Start Date*: 2021-04-30
    Sponsor Name:Radboud UMC
    Full Title: The Efficacy of Ibogaine in the Treatment of Addiction; an open label, single fixed dose pilot-study of the efficacy of ibogaine in opioid-dependent subjects
    Medical condition: Dependence on opiate narcotics
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-023446-70 Sponsor Protocol Number: Start Date*: 2011-07-22
    Sponsor Name:Med. Univ. Wien, Univ. Klinik für Psychiatrie und Psychotherapie
    Full Title: Neural, Genetic, and Peripheral Correlates of SSRI Pharmaco-Response
    Medical condition: Major Depressive Disorder (MDD) remains to be under-recognized and under-treated, though it is amongst the leading causes of disease burden worldwide. Despite the proven efficacy of modern antidepr...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001604-30 Sponsor Protocol Number: 1001 Start Date*: 2017-12-11
    Sponsor Name:Medical University of Vienna
    Full Title: Safety, Tolerability and Efficacy of anti-IL-6 Antibody Clazakizumab in Late Antibody-Mediated Rejection after Kidney Transplantation - A Pilot Trial
    Medical condition: Antibody-mediated rejection of a kidney transplant
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-003723-39 Sponsor Protocol Number: 123/2005/U-26866138-MMY-3006 Start Date*: 2005-07-26
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: A phase 3, prospective, randomized clinical study with Velcade-Thalidomide- Dexamethasone versus Thalidomide-Dexamethasone for previously untreated patients with symptomatic multiple myeloma who ...
    Medical condition: terapia del mieloma nultuplo in pazienti con danno d' organo e assenza di precedente terapia per MM
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028229 Multiple myelomas HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-003484-23 Sponsor Protocol Number: Paccis-RCT_2005 Start Date*: 2010-04-14
    Sponsor Name:Universitätsklinikum Erlangen, Strahlenklinik insoweit handelnd für den Freistaat Bayern
    Full Title: Randomised phase-III-trial of simultaneous radiochemotherapy (RCT) of locally advanced head and neck cancer in the stages III and IV A-B: Comparing dose reduced RCT (63.6 Gy) with Paclitaxel/Cispla...
    Medical condition: Head and Neck cancer, Stage III-IV A-B
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004864 10026518 Malignant neoplasm of supraglottis stage III LLT
    18.0 100000004864 10026185 Malignant neoplasm of oropharynx, unspecified LLT
    18.0 100000004864 10041862 Squamous cell carcinoma of the oral cavity stage III LLT
    18.0 100000004864 10041863 Squamous cell carcinoma of the oral cavity stage IV LLT
    18.0 100000004864 10041855 Squamous cell carcinoma of the hypopharynx stage IV LLT
    18.0 100000004864 10041854 Squamous cell carcinoma of the hypopharynx stage III LLT
    18.0 100000004864 10026519 Malignant neoplasm of supraglottis stage IV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002895-15 Sponsor Protocol Number: EPROBRI-2011 Start Date*: 2012-12-19
    Sponsor Name:Fundación Oftalmológica del Mediterráneo
    Full Title: Prophylactic effect of brimonidine on bleeding subconjunctival in 23G vitrectomy
    Medical condition: Subconjunctival haemorrhages after surgery of vitrectomía with 23G
    Disease: Version SOC Term Classification Code Term Level
    15.0 10015919 - Eye disorders 10042341 Subconjunctival haemorrhage LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2016-003678-42 Sponsor Protocol Number: IIV-316 Start Date*: 2017-09-01
    Sponsor Name:RIVM [...]
    1. RIVM
    2. Clinical Trials and Research Governance
    3. Turun Yliopisto
    Full Title: Immunological effects of an acellular pertussis booster vaccination in children, young adults and elderly with different immunisation background. An international study in Finland, the Netherlands...
    Medical condition: Pertussis infection
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) FI (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-020452-64 Sponsor Protocol Number: version2.0 Start Date*: 2010-10-05
    Sponsor Name:Hull and East Yorkshire Hospitals NHS Trust
    Full Title: A prospective randomisd open label study to determine the effects of intravenous iron administration on markers of acute kidney injury in chronic kidney disease (CKD)
    Medical condition: patients with known chonic kidney disease with functional or absolute Iron deficiency Anaemia, and are greater than 18 years will be given repleacement iron therapy accoring to current local protoc...
    Disease: Version SOC Term Classification Code Term Level
    15.0 10005329 - Blood and lymphatic system disorders 10022973 Iron deficiency anaemias LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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