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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44396   clinical trials with a EudraCT protocol, of which   7408   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,396 result(s) found. Displaying page 152 of 2,220.
    EudraCT Number: 2006-003322-28 Sponsor Protocol Number: BUP4006 Start Date*: 2007-06-21
    Sponsor Name:Norpharma A/S
    Full Title: A randomised, double-blind, multicentre non-inferiority study with active, parallel comparator group, to evaluate the efficacy and safety of Norspan® versus Tramadol in subjects with chronic, mode...
    Medical condition: Chronic, moderate to severe osteoarthritis in hip, knee and/or lumbar spine
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-001321-25 Sponsor Protocol Number: Adenosin, låg- och högdos Start Date*: 2006-05-22
    Sponsor Name:Karolinska Universitetssjukhuset
    Full Title: Prövning av hypotesen att lågdosinfusion av adenosin hos patienter med ischemisk hjärtsjukdom har en prekonditionerande effekt. En placebokontrollerad crossover-studie.
    Medical condition: Patienter med konstaterad kranskärlssjukdom, dvs signifikanta stenoser enl koronarangiografi (LAD-stenos eller 3-kärlssjukdom).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001786-34 Sponsor Protocol Number: IT-04-01 Start Date*: 2005-05-16
    Sponsor Name:ALCON ITALIA
    Full Title: Hypotonic efficacy and tollerability of Travoprost in patient with open angle primary glaucoma and/or ocular hypertension, not controlled with dorzolamide + timolol treatment in fixed association...
    Medical condition: Reducing high intraocular pressure in patient with ocular hypertension or open-angle glaucoma
    Disease: Version SOC Term Classification Code Term Level
    6.1 10030348 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000983-29 Sponsor Protocol Number: MA 17502 Start Date*: 2005-01-12
    Sponsor Name:F. Hoffmann-La Roche Ltd.
    Full Title: Effectiveness of a once weekly subcutaneous epoetin beta treatment in hemodialysis patients.
    Medical condition: Renal anemia in hemodialysis patients
    Disease: Version SOC Term Classification Code Term Level
    7.1 10058116
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-004752-13 Sponsor Protocol Number: MAR-LEV-2005-01 Start Date*: 2006-05-25
    Sponsor Name:H. Universitari Germans Trias i Pujol
    Full Title: Comparación cruzada, a doble ciego, aleatoria, de dosis única, de levocetirizina con desloratadina, rupatadina, ebastina y placebo: supresión de la respuesta de pápula y eritema inducida por histam...
    Medical condition: Rinitis alérgica estacional
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002074-22 Sponsor Protocol Number: UM2005/00201/00 Start Date*: 2006-10-18
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Randomized, Phase III, Open-Label Study of Oral Topotecan Plus Whole-Brain Radiation Therapy (WBRT) Compared with WBRT Alone in Patients with Brain Metastases from Non-Small Cell Lung Cancer.
    Medical condition: Brain metastases from primary non-small cell lung cancer (NSCLC).
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) SK (Completed)
    Trial results: View results
    EudraCT Number: 2005-000727-42 Sponsor Protocol Number: CYT004-MelQbG10 01 Start Date*: 2006-01-20
    Sponsor Name:Cytos Biotechnology AG
    Full Title: A Phase IIa Study to Evaluate Safety, Tolerability, and Immunogenicity of a Melan-A-VLP Vaccine in HLA-A2 Positive Patients with stage III/IV Malignant Melanoma
    Medical condition: Patients with Stage III/IV Malignant Melanoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-000730-20 Sponsor Protocol Number: FP-001-IM Start Date*: 2006-02-02
    Sponsor Name:Nycomed Danmark Aps
    Full Title: An open label, international, multi centre, parallel group, phase III b, randomised trial, investigating lumbar spine Bone Mineral Density (BMD) changes in postmenopausal women with primary osteopo...
    Medical condition: Primary postmenopausal osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031285 Osteoporosis postmenopausal LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: SE (Completed) DE (Completed) GB (Completed) ES (Completed) IT (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2005-000737-38 Sponsor Protocol Number: TS2005 Start Date*: 2005-05-31
    Sponsor Name:RAFAEL GARCIA LOPEZ
    Full Title: NUEVOS ENFOQUES TERAPEUTICOS PARA EL SINDROME DE TOURETTE EN NIÑOS: Estudio fase II para conocer la eficacia y la seguridad del Magnesio y Vitamina B6 para el tratamiento del Síndrome de Tourette ...
    Medical condition: Síndrome de Tourette Tics motores múltiples y uno o más tics vocales, presentes en algún momento durante la enfermedad, aunque no necesariamente al mismo tiempo. Los tics ocurren muchas veces a...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-003115-74 Sponsor Protocol Number: SM4-05 Start Date*: 2005-10-24
    Sponsor Name:Dept. of Anaestesiology, University hospital in Glostrup
    Full Title: Effect of paracetamol versus paracetamol combined with pregabalin versus paracetamol combined with pregabalin and dexamethason on pain and opiod requirements in patient sheduled for tonsilectomie
    Medical condition: Patients scheduled for toncilectomia need postoperative paintreatment. Morphine has sideeffects: Nausea, vomiting, sedation and dizziness. These sideeffects are og couse unpleasent for the patient ...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-003122-25 Sponsor Protocol Number: ICS-1-05 Start Date*: 2005-11-24
    Sponsor Name:ANGEL LANAS
    Full Title: EFECTO DEL ÁCIDO ACETILSALICÍLICO EN LA PROLIFERACIÓN Y APOPTOSIS CELULAR DEL EPITELIO METAPLÁSICO DEL ESÓFAGO DE BARRETT
    Medical condition: Esófago de Barrett.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003627-37 Sponsor Protocol Number: IT-04-04 Start Date*: 2006-09-22
    Sponsor Name:ALCON ITALIA
    Full Title: Hypotonic efficacy and tollerability of concomitant supply of Travoprost e Brinzolamide vs dorzolamide-timololo in fixed association in patient with glaucoma or ocular hypertension clinical study,...
    Medical condition: Patient with glaucoma or ocular hypertension bilateral non controlled
    Disease: Version SOC Term Classification Code Term Level
    6.1 10018307 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-002614-38 Sponsor Protocol Number: HMR1964A/4002 Start Date*: 2006-09-07
    Sponsor Name:SANOFI AVENTIS GROUPE
    Full Title: COMPARISON OF TWO THERAPEUTIC STRATEGIES FOR TREATING TYPE 2 DIABETIC PATIENTS POORLY CONTROLLED WITH BASAL INSULIN ASSOCIATED WITH ORAL ANTIDIABETIC DRUGS: 6-MONTH PROOF OF CONCEPT STUDY
    Medical condition: Type II diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    8.1 10045242 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001297-27 Sponsor Protocol Number: BRN03 Start Date*: 2005-06-08
    Sponsor Name:Neolab td
    Full Title: Comparative Efficacy & Safety of Two Intranasal Fluticasone Propionate Formulations in Persistent Allergic Rhinitis
    Medical condition: Persistent allergic rhinitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000376-14 Sponsor Protocol Number: CLAF237A2309 Start Date*: 2004-05-28
    Sponsor Name:NOVARTIS FARMA
    Full Title: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, ACTIVE CONTROLLED STUDY TO COMPARE THE EFFECT OF 52 WEEKS TREATMENT WITH LAF237 50 MG BID TO METFORMIN UP TO 1000 MG BID IN DRUG NAIVE PATIENTS WITH TYPE 2 ...
    Medical condition: MONOTHERAPY TREATMENT OF PATIENTS WITH TYPE 2 DIABETES
    Disease: Version SOC Term Classification Code Term Level
    6.1 10012601 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-005363-28 Sponsor Protocol Number: AST001 Start Date*: 2006-07-11
    Sponsor Name:Ocera Therapeutics, Inc.
    Full Title: A DOUBLE BLIND, RANDOMIZED, PLACEBO-CONTROLLED MULTICENTER STUDY TO ASSESS THE SAFETY AND EFFICACY OF AST-120 IN MILD TO MODERATELY ACTIVE CROHN’S PATIENTS WITH FISTULAS
    Medical condition: The two main categories of inflammatory bowel disease (IBD) are ulcerative colitis and Crohn’s disease. Crohn’s disease is characterized by recurring episodes of suppurative inflammation of any par...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) BE (Completed) DE (Completed) HU (Completed) AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003906-81 Sponsor Protocol Number: A7-2 Start Date*: 2005-01-14
    Sponsor Name:Oncology Institute of Vilnius University
    Full Title: Chemoradiation with once weekly gemcitabine for invasive bladder cancer
    Medical condition: Invasive transitional cell bladder cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: LT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001045-34 Sponsor Protocol Number: ASL604LIOM02 Studio CPTTS Start Date*: 2005-04-05
    Sponsor Name:AZIENDA USL 6 LIVORNO ZONA LIVORNESE
    Full Title: Metronomic chemiotherapic treatment WITH IRINOTECAN Cpt-11 IN PATIENTS WITH metastatic colon-rectal cancer PHARMACODYNAMIC And PHARMACOKINETIC evaluation.
    Medical condition: Colonrectal metatstatic cancer
    Disease: Version SOC Term Classification Code Term Level
    6.1 10052358 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-001065-41 Sponsor Protocol Number: CSET 2006/1205 Start Date*: 2007-04-30
    Sponsor Name:Institut Gustave Roussy
    Full Title: Phase 2 single-arm studies of gemcitabine in combination with oxaliplatin in refractory and relapsed pediatric solid tumors
    Medical condition: refractory or relapsing malignant pediatric solid tumors
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed) GB (Completed) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004442-16 Sponsor Protocol Number: cro524 Start Date*: 2006-11-29
    Sponsor Name:Imperial College London
    Full Title: Modulation of lung injury complicating lung resection
    Medical condition: Acute respiratory distress syndrome, Acute Lung Injury, Ventilator-Induced Lung Injury
    Disease: Version SOC Term Classification Code Term Level
    8.1 10001052 Acute respiratory distress syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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