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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,349 result(s) found. Displaying page 173 of 2,218.
    EudraCT Number: 2005-000915-80 Sponsor Protocol Number: NB 2006 05 Start Date*: 2005-09-06
    Sponsor Name:University of Birmingham
    Full Title: A phase II study of Topotecan-Vincristine-Doxorubicin (TVD) in children with stage 4 neuroblastoma failing to respond to COJEC
    Medical condition: Neuroblastoma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029260 Neuroblastoma LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000333-38 Sponsor Protocol Number: Hcy2005 Start Date*: 2005-05-25
    Sponsor Name:Organisation name was not entered
    Full Title: A randomized placebo-controlled trial to investigate blood pressure lowering effects of folic acid in patients with borderline hypertension.
    Medical condition: Patients with hyperhomocysteinemia and high-normal blood pressure, otherwise healthy
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002267-24 Sponsor Protocol Number: CRAD001A2413 Start Date*: 2005-07-29
    Sponsor Name:Novartis Pharma Services AG
    Full Title: Assessment of everolimus in addition to calcineurin inhibitors reduction in maintenance renal transplant recipients (ASCERTAIN)
    Medical condition: Renal transplantation
    Disease: Version SOC Term Classification Code Term Level
    M15 10023438
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) FI (Completed) IT (Completed) ES (Completed) DK (Completed) CZ (Completed) HU (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-005223-18 Sponsor Protocol Number: NRA6280030 Start Date*: 2005-05-12
    Sponsor Name:Childrens´ Hospital Erlangen
    Full Title: Evaluation of growth response in short children suffering from a disease with growth retardation and treated with Somatropin: A prospective, longitudinal non-randomised, open, phase II study
    Medical condition: Genotropin®) is approved for treatment of short statured children in specific indications. A benefit can also be achieved in other pathological conditions that lead to growth retardation. Because ...
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002138-36 Sponsor Protocol Number: UHL9927 Start Date*: 2006-02-24
    Sponsor Name:University Hospital of Leicester NHS Trust
    Full Title: Randomised placebo controlled trial of low dose prednisolone for 3-years in subjects with chronic obstructive pulmonary disease with a sputum eosinophilia
    Medical condition: Chronic obstructive pulmonary disease with sputum eosinophilia>3%
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002160-28 Sponsor Protocol Number: hepatology_MT_2005-05 Start Date*: 2005-09-23
    Sponsor Name:Medical University Graz,Department of Internal Medicine, Division of Gastroenterology and Hepatology
    Full Title: Safety and efficacy of long-term treatment with atorvastatin in patients with primary biliary cirrhosis
    Medical condition: Reduction of cardiovascular risk may become key for the management of PBC. Therefore information on safety and efficacy (lipid-lowering effects) of statins in chronic cholestatic disorders is essen...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004343-21 Sponsor Protocol Number: LAM100036 Start Date*: Information not available in EudraCT
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A Multicenter, Double-Blind, Randomized, Parallel-group Evaluation of LAMICTAL Extended-release Adjunctive Therapy in Subjects with Primary Generalized Tonic-Clonic Seizures
    Medical condition: Epilepsy - Primary genralised tonic clonic seizures
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-004346-40 Sponsor Protocol Number: CRAD001A2418 Start Date*: 2005-05-02
    Sponsor Name:Novartis Pharma GmbH
    Full Title: Full title of the trial : Multi-center, open-label, prospective, randomized, parallel group study investigating a CNI-free regimen with Myfortic® and Certican® in comparison to standard therapy wit...
    Medical condition: de novo kidney transplantation (cadaveric, living unrelated or living related)
    Disease: Version SOC Term Classification Code Term Level
    M15 10023438 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002823-15 Sponsor Protocol Number: 1968 Start Date*: 2005-10-25
    Sponsor Name:Nottingham University Hospitals NHS Trust
    Full Title: A PHASE I/II TRIAL OF THE USE OF SIROLIMUS (RAPAMUNE) AND LOW DOSE ARA-C IN OLDER PATIENTS WITH ACUTE MYELOID LEUKAEMIA (AML)
    Medical condition: Acute myeloid leukaemia (AML) and high risk myelodysplasia (MDS)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-002432-10 Sponsor Protocol Number: S308.3.005 Start Date*: 2005-11-25
    Sponsor Name:Solvay Pharmaceuticals
    Full Title: A multicenter, randomized, double-blind, placebo-controlled, ascending dose, parallel group study exploring effects of SLV308 up to 42 mg/day administered as an adjunctive therapy to l-dopa in pati...
    Medical condition: Parkinson Disease late stage
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: MT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001324-36 Sponsor Protocol Number: VERTA Start Date*: 2005-11-08
    Sponsor Name:Instituto Oftalmológico de Alicante (VISSUM)
    Full Title: ENSAYO CLÍNICO DE FASE IIIB, PROSPECTIVO, CONTROLADO, DOBLE CIEGO, ALEATORIZADO CON GRUPOS PARALELOS Y MULTICÉNTRICO PARA COMPARAR LA SEGURIDAD Y LA EFICACIA DE LA TERAPIA FOTODINÁMICA CON VERTEPOR...
    Medical condition: Neovascularización coroidea (NVC) subfoveal secundaria a la degeneración macular asociada a la edad (DMAE)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing) PT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001340-22 Sponsor Protocol Number: BHT-3009-03 Start Date*: 2005-08-12
    Sponsor Name:Bayhill Therapeutics
    Full Title: BHT-3009 IMMUNOTHERAPY IN RELAPSING REMITTING MULTIPLE SCLEROSIS
    Medical condition: Multiple sclerosis results from an auto-immune reaction characterized by inflammation within the nervous system. Myelin basic protein is a target of the autoimmune response and is generally regarde...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) FI (Prematurely Ended) SK (Completed) CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001723-10 Sponsor Protocol Number: 767905/012 Start Date*: 2005-08-26
    Sponsor Name:GlaxoSmithKline R & D Limited
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Efficacy and Safety of Alvimopan 0.5mg Once Daily and 0.5mg Twice Daily for 12 Weeks for the Treatment of O...
    Medical condition: Opioid-induced bowel dysfunction
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed) FI (Completed) GB (Completed) DE (Completed) DK (Completed) EE (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001738-34 Sponsor Protocol Number: 210-03 Start Date*: 2005-07-13
    Sponsor Name:Medivir AB
    Full Title: Phase 2 open-label study of MIV-210 in antiretroviral treatment experienced HIV-1 infected subjects
    Medical condition: HIV-1 infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-004948-45 Sponsor Protocol Number: EXTRADOS Start Date*: 2005-05-08
    Sponsor Name:José Hernández-Quero. Hospital Clínico San Cecilio
    Full Title: Open, multicenter and randomized study phase IV to evaluate the efficacy and safety of 24 weeks more of treatment in patients with chronic hepatitis C genotype 1 and/or 4 co-infected with human inm...
    Medical condition: Chronic hepatitis C
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004952-38 Sponsor Protocol Number: MREC/04/4/016 Start Date*: 2005-02-11
    Sponsor Name:Prof John Yarnold, Institute of Cancer Research
    Full Title: Randomised phase II trial of hyperbaric oxygen therapy in patients with chronic arm lymphoedema after radiotherapy for early breast cancer (HOT)
    Medical condition: Chronic radiation-induced arm lymphoedema.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001060-50 Sponsor Protocol Number: CSPP100A2303 Start Date*: 2005-02-25
    Sponsor Name:Novartis Pharma Services AG
    Full Title: An eight-week, randomized, double-blind, multi-center, active-controlled, parallel group study to evaluate the safety and efficacy of an aliskiren based regimen compared to a lisinopril based regim...
    Medical condition: Hypertension
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-001083-43 Sponsor Protocol Number: BAY 59-7939 / 11223 Start Date*: 2004-11-23
    Sponsor Name:Bayer HealthCare AG
    Full Title: Oral Direct Factor Xa Inhibitor BAY 59-7939 in Patients with acute symptomatic Deep Vein Thrombosis ODIXa-DVT A prospective, randomized, multinational, multicenter, partially blinded, parallel-grou...
    Medical condition: Acute deep vein thrombosis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10051055 Code
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001588-22 Sponsor Protocol Number: BUP-002/04 Start Date*: 2005-06-16
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: PHARMACOKINETIC/PHARMACODINAMIC STUDY OF TRANSDERMAL BUPRENORPHINE FOR TREATMENT OF CHRONIC, MEDIUM-SEVERE, NON-ONCOLOGIC PAIN.
    Medical condition: PATIENTS WITH CHRONIC, MEDIUM-SEVERE, VASCULOPATIC PAIN NON-RESPONDERS TO FANS.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004573-29 Sponsor Protocol Number: DORI-06 Start Date*: 2005-01-21
    Sponsor Name:Peninsula Pharmaceuticals, Inc.
    Full Title: A Multicenter, Phase 3 Study to Confirm the Safety and Efficacy of Intravenous Doripenem in Complicated Lower Urinary Tract Infection or Pyelonephritis
    Medical condition: Complicated Lower Urinary Tract Infection or Pyelonephritis MedDRA: Lower urinary tract infection or pyelonephritis (10024981 and/or 10059517)
    Disease: Version SOC Term Classification Code Term Level
    7.0 10024981 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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