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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44359   clinical trials with a EudraCT protocol, of which   7383   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,359 result(s) found. Displaying page 1,767 of 2,218.
    EudraCT Number: 2016-004491-22 Sponsor Protocol Number: LIFE-PC-01 Start Date*: 2017-09-01
    Sponsor Name:Dept. Clinical Medicine, Aarhus Universit
    Full Title: Early detection of effects of chemotherapy in pancreatic cancer patients – a study using MR-hyperpolarization scanning based on hyperpolarized Pyruvate (13C) injection
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10033575 Pancreas cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2015-003820-30 Sponsor Protocol Number: HYD-HD85/45-CLL-02 Start Date*: 2016-02-22
    Sponsor Name:HYD Pharma Zrt.
    Full Title: A MULTICENTER, SINGLE ARM, OPEN LABEL, EXPLORATORY PROSPECTIVE PHASE II STUDY TO EXPLORE THE EFFICACY, SAFETY AND TOLERABILITY OF DEUTERIUM DEPLETED WATER IN PREVIOUSLY UNTREATED PATIENTS WITH ASYM...
    Medical condition: Previously untreated patients with asymptomatic chronic lymphocytic leukemia but who are at high risk of progression.
    Disease: Version SOC Term Classification Code Term Level
    18.1 100000004864 10060576 Chronic lymphoid leukemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2021-006991-18 Sponsor Protocol Number: 2020/0423/HP Start Date*: 2023-04-21
    Sponsor Name:CHU de Rouen
    Full Title: Postoperative anti-infective strategy following pancreaticoduodenectomy in patients with preoperative biliary stent
    Medical condition: Patients with preoperative biliary stent treated by pancreaticoduodenectomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10073866 Tumor of hepatopancreatic ampulla LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-001576-30 Sponsor Protocol Number: 15783408 Start Date*: 2016-11-07
    Sponsor Name:CHU TOULOUSE
    Full Title: Interest of Intra-nodal injection of gentamicin for the treatment of suppurated cat scratch disease’s lymphadenitis: a randomized controlled study. "BIGG" : Bartonellosis and intra-nodal injection...
    Medical condition: Bartonellosis
    Disease: Version SOC Term Classification Code Term Level
    19.0 10021881 - Infections and infestations 10004145 Bartonellosis PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-002314-17 Sponsor Protocol Number: JR-441-101 Start Date*: 2023-07-03
    Sponsor Name:JCR Pharmaceuticals Co., Ltd.
    Full Title: Phase I/II study of weekly infusions of JR-441 in patients with mucopolysaccharidosis type IIIA
    Medical condition: Mucopolysaccharidosis type IIIA (MPS IIIA) MPS III is an autosomal recessive disease characterized by the accumulation of HS in the tissues throughout the body due to a deficiency in enzymes involv...
    Disease: Version SOC Term Classification Code Term Level
    20.1 10010331 - Congenital, familial and genetic disorders 10056890 Mucopolysaccharidosis III PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-002225-30 Sponsor Protocol Number: 69HCL18_0957 Start Date*: 2019-07-18
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Impact of low protein diet supplemented with ketoanalogues on uremic toxins production and glucose metabolism in chronic kidney disease_KETO GUT study
    Medical condition: chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004857 10076412 Chronic kidney disease stage 5 LLT
    20.0 100000004857 10076411 Chronic kidney disease stage 4 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-001726-99 Sponsor Protocol Number: P17/15 Start Date*: 2021-07-12
    Sponsor Name:Centre Hospitalier de Versailles
    Full Title: Comparison of corticosteroids versus placebo on duration of ventilatory support during severe acute exacerbations of COPD patients in the intensive care unit: a multicentre randomized controlled tr...
    Medical condition: Severe acute exacerbations of Chronic Obstructive Pulmonary Disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-001305-16 Sponsor Protocol Number: 69HCL14_0442 Start Date*: 2017-07-05
    Sponsor Name:Hospices Civils de Lyon - Direction de la Recherche Clinique et de l'Innovation
    Full Title: Assessment of the efficacy of bevacizumab in combination with Folfiri as second-line treatment after the failure of the cisplatin (or carboplatin)-etoposide combination in patients suffering from a...
    Medical condition: Neuroendocrine carcinoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057270 Neuroendocrine carcinoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003309-88 Sponsor Protocol Number: ROR-PH-302 Start Date*: 2020-06-02
    Sponsor Name:United Therapeutics Corporation
    Full Title: A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Ralinepag to Evaluate Safety and Effects on Exercise Capacity Assessed by Cardiopulmonary Exercise Testing in Subjects with World He...
    Medical condition: pulmonary arterial hypertension (PAH)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10077731 Pulmonary hypertension WHO functional class I LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) AT (Prematurely Ended) DE (Prematurely Ended) ES (Ongoing) PL (Prematurely Ended) BE (Completed) IT (Prematurely Ended) PT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-002350-68 Sponsor Protocol Number: F506-CL-0405 Start Date*: 2022-10-12
    Sponsor Name:Astellas Pharma China, Inc.
    Full Title: A Multicenter, Open-label, Non-comparative Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidne...
    Medical condition: liver and kidney transplantation
    Disease:
    Population Age: Newborns, Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2021-004923-34 Sponsor Protocol Number: RSV-MVA-004 Start Date*: 2022-07-07
    Sponsor Name:Bavarian Nordic A/S
    Full Title: A Randomized, Double-blind, Phase 3 Trial to Assess Clinical Efficacy, Safety and Reactogenicity of the Recombinant MVA-BN®-RSV Vaccine in Adults ≥60 Years of Age
    Medical condition: respiratory syncytial virus disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10066742 Respiratory syncytial virus infection prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2020-003414-12 Sponsor Protocol Number: HDP-101-01 Start Date*: 2021-09-09
    Sponsor Name:Heidelberg Pharma AG
    Full Title: A Phase 1/2a, First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of HDP-101 in Patients with Plasma Cell Disorders Including Multiple Myeloma
    Medical condition: Relapsed or refractory Multiple Myeloma (r/r MM)
    Disease: Version SOC Term Classification Code Term Level
    21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned) HU (Trial now transitioned) PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-003929-27 Sponsor Protocol Number: LP0053-2187 Start Date*: 2022-02-08
    Sponsor Name:LEO Pharma A/S (also referred to as LEO Pharma)
    Full Title: Assessing target lesion score via daily photograph capture in subjects with psoriasis vulgaris on the body treated once daily with topical LEO 90100 (calcipotriol 50 mcg/g plus betamethasone 0.5 mg...
    Medical condition: Psoriasis vulgaris
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing) DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2022-003178-22 Sponsor Protocol Number: 91255 Start Date*: 2022-11-16
    Sponsor Name:Unknown at this point Between jobs [...]
    1. Unknown at this point Between jobs
    2. Unknown at this point Between jobs
    Full Title: Intrathecal morphine versus sufentanil in ultra-low dose of isobaric bupivacaine in the management of postoperative pain in patients with hip fractures
    Medical condition: Patients Habile
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10041537 Spinal anaesthesia (all forms) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-002508-42 Sponsor Protocol Number: SBMASTER Start Date*: 2019-12-19
    Sponsor Name:Aarhus University Hospital
    Full Title: A randomized, multicenter, double-blind, placebo-controlled comparison of standard (neo)adjuvant therapy plus placebo versus standard (neo)adjuvant therapy plus atorvastatin in patients with early ...
    Medical condition: Breast Cancer
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004864 10006192 Breast cancer NOS LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2021-000728-36 Sponsor Protocol Number: TQhemi Start Date*: 2021-10-29
    Sponsor Name:Tampere University Hospital
    Full Title: Laparoskooppisen paksusuoliresektion leikkauksen jälkeisten kivunhoitomenetelmien vertailu nykytiedon valossa
    Medical condition: Tutkittavat tulevat paksusuoliresektiotoimenpiteeseen joko paksusuolisyövän tai divertikuloosin vuoksi. Tutkimuksessa selvitetään puudutusmenetelmän vaikutusta toimenpiteen jälkeiseen kivunhoitoon.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10002183 Analgesia intra/post op LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2009-017659-83 Sponsor Protocol Number: - Start Date*: 2010-04-08
    Sponsor Name:BGP Kranj
    Full Title: Intravensko lajšanje porodnih bolečin z remifentanilom, ki si ga uravnava porodnica sama – vpliv hitrosti dovajanja posameznih odmerkov na kvaliteto lajšanja porodnih bolečin in varnost uporabe ...
    Medical condition: labour pain
    Disease: Version SOC Term Classification Code Term Level
    12.1 10059204 Labour pain LLT
    Population Age: In utero, Newborns, Under 18, Adults Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-016752-52 Sponsor Protocol Number: - Start Date*: 2010-03-24
    Sponsor Name:BGP Kranj [...]
    1. BGP Kranj
    2. Katedra za biofarmacijo in farmakokinetiko, Fakulteta za farmacijo
    Full Title: Intravensko lajšanje porodnih bolečin z remifentanilom, ki si ga uravnava porodnica sama – primerjava protokola brez uporabe bazalne infuzije in protokola z uporabo bazalne infuzije glede kvalitete...
    Medical condition: labour pain
    Disease: Version SOC Term Classification Code Term Level
    12.0 10059204 Labour pain LLT
    Population Age: In utero, Newborns, Under 18, Adults Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004304-19 Sponsor Protocol Number: AMAG-FER-IDA-352 Start Date*: 2019-07-10
    Sponsor Name:AMAG Pharmaceuticals, Inc.
    Full Title: A Phase 3, Randomized, Open-Label, Multicenter Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects
    Medical condition: Iron Deficiency Anemia (IDA) in Pediatric Subjects
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004851 10022974 Iron deficiency anemia LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: LT (Trial now transitioned) PL (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-003381-33 Sponsor Protocol Number: EMR-62202-717 Start Date*: 2007-08-30
    Sponsor Name:Institute of Oncology Ljubljana
    Full Title: Induction chemotherapy followed by chemoradiation with cetuximab and cisplatin for inoperable squamous cell carcinoma of the head and neck.
    Medical condition: Inoperable squamous cell carcinoma of the head and neck.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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