Flag of the European Union EU Clinical Trials Register Help

Clinical trials for Perioperative mortality

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
    How to search [pdf]
    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
    Advanced Search: Search tools
     
    101 result(s) found for: Perioperative mortality. Displaying page 2 of 6.
    « Previous 1  2  3  4  5  6  Next»
    EudraCT Number: 2017-003832-35 Sponsor Protocol Number: HIPEC/FLOT9 Start Date*: 2020-07-27
    Sponsor Name:Institute of Clinical Cancer Research (IKF) Krankenhaus Nordwest
    Full Title: Preventive HIPEC in combination with perioperative FLOT versus FLOT alone for resectable diffuse type gastric and gastroesophageal junction Type II/III adenocarcinoma – The phase III “PREVENT” tri...
    Medical condition: locally advanced resectable diffuse type adenocarcinoma of the oesophagogastric junction or the stomach
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062878 Gastrooesophageal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000539-29 Sponsor Protocol Number: 2018.02.08 Start Date*: 2018-12-11
    Sponsor Name:Hamilton Health Sciences Corporation
    Full Title: PeriOperative ISchemic Evaluation-3 (POISE-3) Trial
    Medical condition: The occurrence of life-threatening, major, and critical organ bleeding, and, major arterial and venous thrombosis in patients undergoing noncardiac surgery. And for patients in the blood pressure m...
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10043611 Thrombosis arterial LLT
    21.0 100000004866 10043640 Thrombosis venous LLT
    23.1 100000004863 10051014 Post procedural bleeding LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DK (Completed) AT (Completed) NL (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2017-003714-68 Sponsor Protocol Number: 1744/2017 Start Date*: 2017-11-15
    Sponsor Name:Medical University of Vienna
    Full Title: Effect of Supplemental Oxygen on Perioperative Brain Natriuretic Peptide Concentration in Cardiac Risk Patients - A prospective randomized clinical trial
    Medical condition: Evaluation of the effect of 80% versus 30% supplemental oxygen administration during major abdominal surgery on postoperative brain natriuretic peptide concentration.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10059883 Fraction of inspired oxygen PT
    20.0 100000173317 10050322 Oxygen supplementation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002076-14 Sponsor Protocol Number: EPICSstudy Start Date*: 2014-05-12
    Sponsor Name:
    Full Title: Pre-operative treatment with Erythropoietin and iron supplement for prevention of perioperative blood transfusion in cardiac surgery
    Medical condition: Patients (male and female) scheduled for coronary artery bypass grafting surgery (CABG) or single Aortic Valve replacement (AVR) on conventional cardiopulmonary bypass.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-004938-11 Sponsor Protocol Number: PI-GR-21-2386 Start Date*: 2021-12-21
    Sponsor Name:Hospital Clínico Universitario de Valladolid
    Full Title: Prevention of cardiac surgery-associated acute kidney injury through the use of sodium-glucose cotransporter 2 inhibitors
    Medical condition: Cardiac surgery-associated acute kidney injury
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-001728-20 Sponsor Protocol Number: RACE Start Date*: 2020-01-17
    Sponsor Name:Ruprecht-Karls-Universität Heidelberg
    Full Title: - RACE - Neoadjuvant Radiochemotherapy versus Chemotherapy for Patients with Locally Advanced, Potentially Resectable Adenocarcinoma of the Gastroesophageal Junction (GEJ) A randomized phase III j...
    Medical condition: Locally Advanced, Potentially Resectable Adenocarcinoma of the Gastroesophageal Junction (GEJ)
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062878 Gastrooesophageal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2018-000263-92 Sponsor Protocol Number: 17-251 Start Date*: 2018-05-28
    Sponsor Name:CHU CAEN
    Full Title: Spironolactone and perioperative atrial fibrillation occurrence in cardiac surgery patients: a multicenter randomized, double-blind study
    Medical condition: Patients > 18 years referred for elective cardiac bypass graft (CABG) surgery ± aortic valve replacement (AVR) without any systolic heart failure or any mitral surgery associated
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-002936-34 Sponsor Protocol Number: iPROVE-O2-16 Start Date*: 2017-01-30
    Sponsor Name:Francisco Javier Belda Nacher
    Full Title: Effects on surgical site infection of an individualized perioperative openlung ventilatory strategy with high versus conventional inspiratory oxygen fraction (iPROVEO2). A comparative, prospective,...
    Medical condition: The study population will be patients who are scheduled for major abdominal (laparotomy and laparoscopic) surgery under general anaesthesia.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001979-23 Sponsor Protocol Number: DANTE/FLOT8 Start Date*: 2018-06-06
    Sponsor Name:Frankfurter Institut für Klinische Krebsforschung IKF GmbH am Krankenhaus Nordwest
    Full Title: A randomized, open-label Phase II/III efficacy and safety study of Atezolizumab in combination with FLOT versus FLOT alone in patients with gastric cancer and adenocarcinoma of the oesophago-gastri...
    Medical condition: locally advanced resectable adenocarcinoma of the oesophagogastric junction or the stomach
    Disease: Version SOC Term Classification Code Term Level
    20.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10062878 Gastrooesophageal cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2016-003413-10 Sponsor Protocol Number: ACDHUVV-16 Start Date*: 2016-12-20
    Sponsor Name:FIMABIS
    Full Title: MicroRNAs expression analysis in patients undergoing cardiac surgery treated with halogenated anesthetics. Identification of microRNAs related to the cardioprotective effect
    Medical condition: Cardiac surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-003818-92 Sponsor Protocol Number: CURITIBA_TRIAL Start Date*: 2014-12-22
    Sponsor Name:Ospedale San Raffaele, UO Chirurgia Vascolare
    Full Title: CUstodiol vs RInger: whaT Is the Best Agent?
    Medical condition: Thoracoabdominal aortic aneurysm
    Disease: Version SOC Term Classification Code Term Level
    17.1 10047065 - Vascular disorders 10002882 Aortic aneurysm PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2020-002586-34 Sponsor Protocol Number: STEROID_MC_1 Start Date*: 2020-11-12
    Sponsor Name:Department of Anesthesiology, Copenhagen University Hospital Hvidovre, Capital Region of Denmark
    Full Title: The effects of preoperative high-dose Dexamethasone on inflammatory response and recovery after emergency laparotomy, a randomized, double-blind, placebo-controlled clinical trial - AHA STEROID ...
    Medical condition: Patients undergoing emergency laparotomy due to either Intestinal obstruction or perforated abdominal viscus.
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10053361 Explorative laparotomy PT
    20.1 10018065 - General disorders and administration site conditions 10051379 Systemic inflammatory response syndrome PT
    22.0 10017947 - Gastrointestinal disorders 10021328 Ileus PT
    20.0 10017947 - Gastrointestinal disorders 10034406 Perforation bowel LLT
    20.0 10017947 - Gastrointestinal disorders 10034430 Perforation stomach LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2020-006001-35 Sponsor Protocol Number: PREBOT-II Start Date*: 2021-10-27
    Sponsor Name:University Hospital Heidelberg
    Full Title: Randomized controlled trial of PREoperative injection of BOTulinum toxin into the sphincter of Oddi to reduce bile leakage after hepatic resection PREBOT-II
    Medical condition: Patients undergoing partial hepatic resection for various underlying diseases.
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004865 10077348 Liver resection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-018173-31 Sponsor Protocol Number: POISE-2 Start Date*: 2011-02-25
    Sponsor Name:Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
    Full Title: Ensayo clínico factorial de clonidina y aspirina en pacientes que van a ser sometidos a cirugía no cardiaca y que estén en riesgo moderado o alto de sufrir eventos cardíacos perioperatorios (Estudi...
    Medical condition: Prevención de episodios cardiovasculares en pacientes de moderado a alto riesgo cardiovascular que son sometidos a una cirugía no cardiaca.
    Disease: Version SOC Term Classification Code Term Level
    9 10007649 Cardiovascular disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed) AT (Completed) BE (Completed) DK (Completed) GB (Completed) DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-002333-21 Sponsor Protocol Number: 1 Start Date*: 2006-07-28
    Sponsor Name:Allgemeines Krankenhaus Wien, Medizinische Un iversität Wien [...]
    1. Allgemeines Krankenhaus Wien, Medizinische Un iversität Wien
    2. Allgemeines Krankenhaus Wien, Medizinische Universität Wien
    Full Title: Intraoperative Goal-Directed Fluid Therapy in Lean and Obese Patients
    Medical condition: Hemodynamics in obese patients differ from lean patients: Obese patients have a higher cardiac output, the absolute amount of their intravascular volume is increased, as is the intracellular volume...
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-004814-33 Sponsor Protocol Number: MOFA Start Date*: 2006-03-23
    Sponsor Name:Gesellschaft für Wissens- und Technologietransfer
    Full Title: Metabolic optimized fast track concept in general surgery
    Medical condition: Carcinoma of the colon or the liver scheduled for surgical resection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2022-001393-58 Sponsor Protocol Number: T21-118 Start Date*: 2023-04-13
    Sponsor Name:Hagaziekenhuis
    Full Title: POMPAE trial: Peri-Operative Magnesium infusion to Prevent Atrial fibrillation Evaluated.
    Medical condition: Atrial fibrillation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2016-001313-24 Sponsor Protocol Number: SUPERADD Start Date*: 2017-02-13
    Sponsor Name:Technische Universität München, Fakultät für Medizin
    Full Title: SUbstition of PERioperative Albumin Deficiency Disorders
    Medical condition: High risk surgical patients or procedures showing a hypoalbuminemia intraoperatively.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10022891 - Investigations 10005286 Blood albumin abnormal PT
    20.0 10022891 - Investigations 10005287 Blood albumin decreased PT
    20.1 10027433 - Metabolism and nutrition disorders 10020943 Hypoalbuminemia LLT
    20.0 10027433 - Metabolism and nutrition disorders 10020942 Hypoalbuminaemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-003684-19 Sponsor Protocol Number: 15-163 Start Date*: 2018-02-08
    Sponsor Name:RWTH Aachen, represented by the Rector, himself represented by the Dean of the Medical Faculty
    Full Title: Xenon-anesthesia on patients undergoing major liver-resection: randomized controlled trial
    Medical condition: post-resectional liver failure
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000415-25 Sponsor Protocol Number: PROSPER Start Date*: 2018-08-10
    Sponsor Name:University Hospital Heidelberg
    Full Title: PANCREATIC RESECTION WITH PERIOPERATIVE OFF-LABEL STUDY OF PROPRANOLOL AND ETODOLAC – A PHASE II RANDOMIZED TRIAL
    Medical condition: Patients with pancreatic carcinoma treated by pancreatoduodenectomy.
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004865 10033659 Pancreatoduodenectomy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    Download Options:
    Number of Trials to download:
    Download Content:
    Download Format:
    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
    « Previous 1  2  3  4  5  6  Next»
    Query did not match any studies.
    For support, Contact us.
    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

    European Medicines Agency © 1995-Thu Feb 12 07:09:41 CET 2026 | Domenico Scarlattilaan 6, 1083 HS Amsterdam, The Netherlands
    EMA HMA