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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44393   clinical trials with a EudraCT protocol, of which   7405   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,393 result(s) found. Displaying page 205 of 2,220.
    EudraCT Number: 2009-010436-17 Sponsor Protocol Number: CPNM-RT-09 Start Date*: 2009-09-09
    Sponsor Name:ASOCIACION TERAPEUTICA EN HEMATOLOGIA Y ONCOLOGIA MEDICAS DEL HOSPITAL ARNAU DE VILANOVA DE VALENCIA
    Full Title: Ensayo clínico en fase II de la combinación de vinorelbina oral y cisplatino, administrada en inducción y concomitante con radioterapia, en pcaientes con cácner de pulmón no microcítico (CPNM) loca...
    Medical condition: Cáncer de pulmón no microcítico irresecable en estadios IIIA y IIIB
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-019345-26 Sponsor Protocol Number: 03-AnIt-10 Start Date*: 2010-06-02
    Sponsor Name:Department of Anesthesiology and Intensive Care, University Hospital Muenster
    Full Title: Immunmodulatory effects of local anesthetics on neutrophils during sepsis
    Medical condition: Sepsis and severe sepsis
    Disease: Version SOC Term Classification Code Term Level
    12.1 10040047 Sepsis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-004224-23 Sponsor Protocol Number: TSAIMT01 Start Date*: 2009-03-13
    Sponsor Name:University of Glasgow / NHS Greater Glasgow and Clyde
    Full Title: The effect of allopurinol on carotid ultrasound intima-media thickness and markers of endothelial function in patients with recent stroke - a pilot study.
    Medical condition: Ischaemic stroke or transient ischaemic attack (TIA) (ICD Classification Code I63.0-9 and G45.0-1).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10061256 Ischaemic stroke LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006474-28 Sponsor Protocol Number: NBI-56418-0703 Start Date*: 2008-05-14
    Sponsor Name:Neurocrine Biosciences, INC
    Full Title: A Phase II, Randomized, Double-Blind, Placebo- and Active-Controlled Study to Assess the Efficacy and Safety of NBI-56418 in Subjects with Endometriosis
    Medical condition: Endometriosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10014778 Endometriosis LLT
    Population Age: Adults Gender: Female
    Trial protocol: HU (Completed) PL (Completed) BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-019937-85 Sponsor Protocol Number: dmestatina Start Date*: 2010-09-16
    Sponsor Name:Dr. Luis Serra Majem
    Full Title: Dieta Mediterránea, Ejercicio y Estatinas en el Tratamiento de la Dislipemia
    Medical condition: Dislipidemia
    Disease: Version SOC Term Classification Code Term Level
    11 10058108 Dislipidemia PT
    Population Age: Adults Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-017376-25 Sponsor Protocol Number: MEK111759 Start Date*: 2011-03-15
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: An Open-Label, Dose-Escalation, Phase I/II Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of the MEK Inhibitor GSK1120212 in Subjects with Relapsed or Ref...
    Medical condition: Relapsed or refractory leukemias
    Disease: Version SOC Term Classification Code Term Level
    12.1 10000880 Acute myeloid leukaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007346-63 Sponsor Protocol Number: ALS-003-2008 Start Date*: 2011-04-05
    Sponsor Name:Alloksys Life Sciences B.V.
    Full Title: Reumap: An Open Label phase II study of Bovine Intestinal Alkaline Phosphatase (bIAP), An Inflammation modulating moiety, in RA patients
    Medical condition: Rheumatoid Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Temporarily Halted)
    Trial results: (No results available)
    EudraCT Number: 2008-007404-28 Sponsor Protocol Number: HRT Start Date*: 2009-02-12
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: Role of Estrogens in osteoclastogenesis and immunomodulation of T cells.
    Medical condition: post-menopausal osteoporosis
    Disease: Version SOC Term Classification Code Term Level
    9.1 10031282 Osteoporosis LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007406-11 Sponsor Protocol Number: ENB-002-08 Start Date*: 2009-02-25
    Sponsor Name:Enobia Canada Limited Partnership
    Full Title: A Multicenter, Open-Label Study of the Safety, Tolerability and Pharmacology of ENB-0040 (Enobia’s human recombinant tissue non-specific alkaline phosphatase fusion protein) in up to 6 Severely Aff...
    Medical condition: Infantile Hypophosphatasia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10010331 - Congenital, familial and genetic disorders 10049933 Hypophosphatasia PT
    Population Age: Newborns, Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-016066-91 Sponsor Protocol Number: EPO200901 Start Date*: 2010-03-10
    Sponsor Name:ISTITUTO NEUROLOGICO "CARLO BESTA"
    Full Title: SAFETY AND EFFICACY OF ERYTHROPOIETIN IN AMYOTROPHIC LATERAL SCLEROSIS: A RANDOMIZED, PLACEBO-CONTROLLED CLINICAL TRIAL
    Medical condition: ALS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006826-33 Sponsor Protocol Number: CHU-P 2008-07 Start Date*: 2009-03-20
    Sponsor Name:CHU d'Angers
    Full Title: Effet d’une prémédication sur la douleur, en IRM fonctionnelle, chez des volontaires sains.
    Medical condition: volontaire sain en situation de prémédication identique à celle administrée avant une intervention chirurgicale.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-022011-19 Sponsor Protocol Number: PA-CL-05A Start Date*: 2011-02-21
    Sponsor Name:Vifor (International) Inc.
    Full Title: An Open-label, Randomised, Active-controlled, Parallel Group, Multicentre, Phase 3 Study to Investigate the Safety and Efficacy of PA21 Compared with Sevelamer Carbonate Followed by a Randomised Co...
    Medical condition: Control of hyperphosphataemia in patients with chronic kidney disease on dialysis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease LLT
    14.0 10027433 - Metabolism and nutrition disorders 10020711 Hyperphosphataemia PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) CZ (Completed) LV (Completed) LT (Completed) SE (Completed) AT (Completed) DE (Completed) BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001075-35 Sponsor Protocol Number: TG-M-003 Start Date*: 2007-04-12
    Sponsor Name:ThromboGenics Ltd.
    Full Title: AN OPEN-LABEL CLINICAL TRIAL OF INTRA-ARTERIAL MICROPLASMIN ADMINISTRATION IN PATIENTS WITH ACUTE INTRACRANIAL VERTEBROBASILAR ARTERY OCCLUSION
    Medical condition: ACUTE INTRACRANIAL VERTEBROBASILAR ARTERY OCCLUSION RESULTING IN ACUTE ISCHEMIC STROKE
    Disease: Version SOC Term Classification Code Term Level
    8.1 10048963 Basilar artery occlusion LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016789-10 Sponsor Protocol Number: 02-04-80 Start Date*: 2010-02-19
    Sponsor Name:Div KIR AMC
    Full Title: Efficacy of the H1N1 Flu (swine flu) vaccination in patients with Rheumatoid Arthritis treated with rituximab
    Medical condition: To assess the efficacy of A/H1N1 vaccination in patients treated with rituximab therapy
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004578-15 Sponsor Protocol Number: 01082007 Start Date*: 2008-03-03
    Sponsor Name:Dutch Heart Foundation
    Full Title: A randomised, double blind placebo controlled trial to (A) assess the optimal vitamin K dosage for supplementation, and (B) to access whether complications of anticoagulation treatment will diminis...
    Medical condition: Anti-coagulationtreatment with vitamine K antagonists.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10058768 Vitamin K LLT
    9.1 10053755 Vitamin K antagonist LLT
    9.1 10009728 Coagulation and bleeding analyses HLT
    9.1 10043607 Thrombosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-004584-22 Sponsor Protocol Number: D0520C00003 Start Date*: 2007-11-21
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomised, Double-Blind, Placebo-Controlled, Two-Way Crossover Study in Healthy Volunteers to Investigate the Effect of Oral Dosing with AZD9668 on Airway Inflammation as Assessed in Induced Spu...
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10010952 COPD LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2009-017525-19 Sponsor Protocol Number: 77777 Start Date*: 2010-03-12
    Sponsor Name:St. Vincents University Hospital, Department of Rheumatology.
    Full Title: Abatacept in Psoriasis and Psoriatic Arthritis: a single centre, placebo-controlled, crossover study in 15 patients.
    Medical condition: Psoriatic Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017537-21 Sponsor Protocol Number: PHT/2009/36 Start Date*: 2010-03-02
    Sponsor Name:Portsmouth Hospitals NHS Trust
    Full Title: Oral thiamine (Vitamin B1) supplementation in subjects with type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled crossover trial assessing biophysical markers of endothelial fun...
    Medical condition: Type 2 diabetes
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017591-24 Sponsor Protocol Number: H8Z-MC-JACW Start Date*: Information not available in EudraCT
    Sponsor Name:Eli Lilly and Company
    Full Title: A Randomized Phase 2 Study of LY2181308 in Combination with Docetaxel versus Docetaxel in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer who Were Previously Treated with Fi...
    Medical condition: Locally Advanced or Metastatic Non-Small Cell Lung Cancer
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061873 Non-small cell lung cancer PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed) BE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2009-017599-26 Sponsor Protocol Number: WS508648 Start Date*: 2010-01-12
    Sponsor Name:CENTRO PER LA PREVENZIONE E CURA DEL TABAGISMO
    Full Title: EFFICACY AND SAFETY OF SMOKING CESSATION WITH VARENICLINE TARTRATE IN DIBETIC SMOKERS: A DOUBLE-BLIND,PLACEBO-CONTROLLED, RANDOMIZED, TRIAL
    Medical condition: diabetic smokers
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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