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Clinical trials for Connective Tissue Diseases AND Skin and Connective Tissue Diseases

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44334   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,106 result(s) found for: Connective Tissue Diseases AND Skin and Connective Tissue Diseases. Displaying page 21 of 56.
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    EudraCT Number: 2013-002266-40 Sponsor Protocol Number: CAIN457ADE02 Start Date*: 2013-12-09
    Sponsor Name:Novartis Pharma GmbH
    Full Title: A randomized, double-blind, placebo-controlled, multicenter, exploratory evaluation of surrogate markers of cardiovascular risk in patients with active chronic plaque-type psoriasis treated for 52 ...
    Medical condition: active chronic plaque-type psoriasis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2014-004612-10 Sponsor Protocol Number: BAY86-5300/91772 Start Date*: 2015-01-12
    Sponsor Name:Bayer HealthCare AG
    Full Title: A multicenter, double-blind, randomized, placebo controlled study to evaluate the efficacy and safety of an oral contraceptive preparation YAZ (drospirenone 3 mg / ethinylestradiol 20 µg) for 6 tre...
    Medical condition: Acne Vulgaris
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004858 10000519 Acne vulgaris LLT
    Population Age: Adolescents, Under 18, Adults Gender: Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2011-006283-42 Sponsor Protocol Number: KAD166 Start Date*: 2012-04-30
    Sponsor Name:Dr. Kade Pharmazeutische Fabrik GmbH
    Full Title: Placebo-controlled double-blind trial investigating the efficacy and tolerability of Posterisan® akut with lidocaine (50 mg/g rectal ointment) in abatement of complaints associated with the anorect...
    Medical condition: Relief of complaints associated with anorectal symptom complex (pain, burning, itching)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10002580 Anorectal therapeutic procedures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2016-002714-45 Sponsor Protocol Number: FJD-MET-2016-01 Start Date*: 2017-01-13
    Sponsor Name:Instituto de Investigación Sanitaria Fundación Jiménez Díaz
    Full Title: "Pilot study to assess the efficacy of treatment with metformin in patients with Hidradenitis suppurativa refractory to standard treatment "
    Medical condition: Hidradenitis suppurativa
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003867-21 Sponsor Protocol Number: LP0160-1327 Start Date*: 2017-10-30
    Sponsor Name:LEO Pharma A/S
    Full Title: A phase 4 trial comparing the efficacy of subcutaneous injections of brodalumab to oral administrations of fumaric acid esters in adults with moderate to severe plaque psoriasis
    Medical condition: moderate to severe plaque psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-005288-29 Sponsor Protocol Number: P1204LT Start Date*: 2013-06-07
    Sponsor Name:G. Pohl-Boskamp GmbH & Co. KG
    Full Title: A single-center randomized, active-controlled, observer-blinded, parallel group trial to evaluate the efficacy and safety of a topical dimeticone formulation (Loion®) compared to 10% saliclylic aci...
    Medical condition: psoriatic plaques in patients with chronic psoriasis capitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004858 10037157 Psoriasis of scalp LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-004370-28 Sponsor Protocol Number: 11-03/FusBet-C Start Date*: 2012-06-25
    Sponsor Name:Dermapharm AG
    Full Title: Double-blind, randomized clinical trial to compare the efficacy and safety of fusidic acid 2% betamethasone 0,1% cream vs. Fucicort cream vs. vehicle for patients with bacterial infected eczemas.
    Medical condition: Bacterial infected eczemas
    Disease: Version SOC Term Classification Code Term Level
    17.1 10021881 - Infections and infestations 10014199 Eczema infected PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2013-005003-14 Sponsor Protocol Number: Pro_MC2-01_13_Biotek Start Date*: 2014-04-02
    Sponsor Name:Drug Delivery Solutions ApS
    Full Title: A randomized, multi-centre, observer-blind, controlled exploratory study to assess efficacy and safety of new topical formulations (MC2-01) in patients with plaque psoriasis
    Medical condition: Patients with stable plaque type psoriasis (sufficient number and size of psoriatic plaques(s)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2021-001442-35 Sponsor Protocol Number: PTZ Start Date*: 2021-06-04
    Sponsor Name:ISTITUTI FISIOTERAPICI OSPITALIERI
    Full Title: A PHASE 2 MONOCENTRIC PILOT STUDY TO EVALUATE THE EFFICACY AND SAFETY PROFILE OF PIOGLITAZONE IN SUBJECTS WITH ACTIVE NON-SEGMENTAL VITILIGO
    Medical condition: NON SEGMENTAL VITILIGO WITH BSA BETWEEN 2% AND 50% AND A NON-SATISFACTORY RESPONSE (LESS THAN 10%) TO A PREVIOUS PHOTOTHERAPY CYCLE
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004858 10047643 Vitiligo vulgaris LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-000294-78 Sponsor Protocol Number: CTP001H Start Date*: 2019-06-07
    Sponsor Name:Nektr Technologies
    Full Title: A Randomized, Single-Blinded, Comparative Study of Mycosinate and Curanail in the Treatment of Fungal Nail Infection
    Medical condition: Onychomycosis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000097-30 Sponsor Protocol Number: 2018-PSO-IL17R Start Date*: 2018-04-18
    Sponsor Name:Herlev and Gentofte Hospital
    Full Title: Efficacy of brodalumab in patients with psoriasis with failure of other anti-IL-17 treatments
    Medical condition: Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10050576 Psoriasis vulgaris LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-001971-38 Sponsor Protocol Number: HARRAS1/2006 Start Date*: 2012-01-05
    Sponsor Name:HARRAS-PHARMA-CURARINA GmbH
    Full Title: Comparative Study with a Propolis Cream vs. Aciclovir Cream in Patients with Herpes labialis A single-blind, randomised, two-arm study
    Medical condition: Herpes labialis Single-blind, randomised, controlled parallel group comparison of a Propolis special extract GH 2002 cream (Herpetino® Balsam) and an aciclovir 5% containing cream. Up to 10 day...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2012-004372-19 Sponsor Protocol Number: HARRAS1/2012 Start Date*: 2013-06-05
    Sponsor Name:HARRAS-PHARMA-CURARINA GmbH
    Full Title: Comparative Study with a Propolis Cream vs. Aciclovir Cream in Patients with Herpes labialis A double-blind, randomised, two-arm study
    Medical condition: Herpes labialis Double-blind, randomised, controlled parallel group comparison of a Propolis special extract GH 2002 cream (Herpetino® Balsam) and an aciclovir 5% containing cream. Up to 10 day...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed)
    Trial results: View results
    EudraCT Number: 2014-000334-30 Sponsor Protocol Number: INT27/14 Start Date*: 2014-09-17
    Sponsor Name:Fondazione IRCCS ''IStituto Nazionale dei Tumori''
    Full Title: Immunomodulatory effect of esomeprazole antitumoral and high-dose under neoadjuvant and adjuvant in patients with melanoma in stage III. Randomized pilot study treatment vs control
    Medical condition: metastatic melanoma BLS+ and BRAF wt
    Disease: Version SOC Term Classification Code Term Level
    16.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025670 Malignant melanoma stage III PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2014-003691-23 Sponsor Protocol Number: 50621 Start Date*: 2014-11-10
    Sponsor Name:Maastricht Universitair Medisch Centrum
    Full Title: Topical Ingenol mebutate versus 5% 5-fluorouracil versus 5% Imiquimod versus photodynamic therapy in the treatment of actinic keratosis: a multi-center randomized efficacy and cost-effectiveness st...
    Medical condition: Actinic keratosis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2018-001743-31 Sponsor Protocol Number: 18-03/MPA-M Start Date*: Information not available in EudraCT
    Sponsor Name:Dermapharm AG
    Full Title: Double-blind, randomised clinical study comparing efficacy and safety of Methylprednisolone Aceponate 0.1% Cutaneous emulsion (Test) vs. Advantan Milk 0.1% Cutaneous emulsion (Reference) vs. Vehicl...
    Medical condition: Atopic dermatitis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10003639 Atopic dermatitis LLT
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005726-30 Sponsor Protocol Number: CURES-IL1T-OT-1236 Start Date*: 2014-04-28
    Sponsor Name:Charité - Universitätsmedizin
    Full Title: A multi-center, double-blind placebo-controlled parallel group phase II study of the efficacy and safety of rilonacept in subjects with cold contact urticaria (CCU)
    Medical condition: cold contact urticaria (CCU)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-003944-38 Sponsor Protocol Number: 15-PP-13 Start Date*: 2016-04-19
    Sponsor Name:CHU NICE
    Full Title: Treatment of the oral aphtose récidivante and idiopathique of the adult by probiotics Double-blind randomized interventional study versus placebo
    Medical condition: aphtous stoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2018-003487-31 Sponsor Protocol Number: 1407-0005 Start Date*: 2019-07-17
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: Phase II long-term extension study to assess the safety, tolerability, and efficacy of BI 730357 in patients with moderate-to-severe plaque psoriasis
    Medical condition: Plaque Psoriasis
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004858 10071117 Plaque psoriasis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-004067-31 Sponsor Protocol Number: OA-orMSCp-02 Start Date*: 2018-12-21
    Sponsor Name:Bioinova, s.r.o.
    Full Title: Autologous bone marrow-derived mesenchymal stem cells seeded on a 3D scaffold in treatment of knee cartilage defects. Prospective open-label study to assess safety and feasibility.
    Medical condition: Knee Cartilage Defect
    Disease: Version SOC Term Classification Code Term Level
    20.1 10022117 - Injury, poisoning and procedural complications 10007710 Cartilage injury PT
    20.0 10042613 - Surgical and medical procedures 10052913 Cartilage operation PT
    20.0 10042613 - Surgical and medical procedures 10057104 Cartilage repair LLT
    21.0 100000004859 10072638 Articular cartilage defect LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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