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Clinical trials for II

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    11,928 result(s) found for: II. Displaying page 282 of 597.
    EudraCT Number: 2018-001481-42 Sponsor Protocol Number: ITFE-2026-C11 Start Date*: 2018-10-04
    Sponsor Name:ITF RESEARCH PHARMA S.L.U.
    Full Title: Prospective, multicentre, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy of a 0.005% estriol vaginal gel in the prevention of recurrent urinary tract infection...
    Medical condition: Recurrent Urinary Tract Infection (UTI) in postmenopausal women with vaginal atrophy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10038140 Recurrent urinary tract infection LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003936-62 Sponsor Protocol Number: PRONE Start Date*: 2019-06-13
    Sponsor Name:HOSPITAL UNIVERSITARI DE BELLVITGE-IDIBELL
    Full Title: RENINE ANGIOTENSINE SYSTEM BLOCKADE (RAAS) IN RENAL TRANSPLANT RECIPIENTS WITH RENAL PROGENITOR CELLS (PEC's) IN URINE: RANDOMIZED CLINICAL TRIAL
    Medical condition: POST TRANSPLANT RENAL GLOMERULOPATHY
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10038533 Renal transplant PT
    20.1 100000004870 10063210 Transplant glomerulopathy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-003571-19 Sponsor Protocol Number: RBH2019/001 Start Date*: 2020-05-21
    Sponsor Name:Royal Brompton and Harefield NHS Foundation Trust
    Full Title: PAciFy Cough: A multicentre, double blind, placebo controlled, crossover trial of morphine sulfate for the treatment of PulmonAry Fibrosis Cough
    Medical condition: Idiopathic pulmonary fibrosis
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038738 - Respiratory, thoracic and mediastinal disorders 10021240 Idiopathic pulmonary fibrosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2020-001576-15 Sponsor Protocol Number: MK-3009-029 Start Date*: 2020-05-28
    Sponsor Name:Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
    Full Title: A Phase II Open-Label, Single-arm Clinical Trial to Study the Safety, Efficacy and Pharmacokinetics of MK-3009 (Daptomycin) in Japanese Pediatric Participants Aged 1 to 17 Years with Complicated Sk...
    Medical condition: Complicated Skin and Soft Tissue Infections or Bacteremia caused by Gram-positive cocci
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10060945 Bacterial infection PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-002672-12 Sponsor Protocol Number: 73807 Start Date*: 2020-12-11
    Sponsor Name:Erasmus Medical Center
    Full Title: Frontotemporal dementia Imaging of Neuroinflammation, Degeneration and Microglia-Related Effects
    Medical condition: Frontotemporal dementia (FTD), including symptomatic patients and presymptomatic individuals with genetic mutations predisposing to FTD at a later stage in life.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-004665-10 Sponsor Protocol Number: GIADA-CA209-959 Start Date*: 2017-06-27
    Sponsor Name:DIPARTIMENTO SCIENZE CHIRURGICHE, ONCOLOGICHE E GASTROENTEROLOGICHE (DISCOG) - UNIVERSITA' DI PADOVA
    Full Title: THE GIADA TRIAL. ENGAGING THE IMMUNE SYSTEM TO IMPROVE THE EFFICACY OF NEOADJUVANT CHEMO-ENDOCRINE THERAPY FOR PREMENOPAUSAL LUMINAL B BREAST CANCER PATIENTS.
    Medical condition: Hormone-sensitive, HER-negative, Luminal B, premenopausal Breast cancer
    Disease: Version SOC Term Classification Code Term Level
    23.0 100000004864 10070577 Oestrogen receptor positive breast cancer LLT
    Population Age: Adults Gender: Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000362-12 Sponsor Protocol Number: K-832-2.01EU Start Date*: 2004-07-23
    Sponsor Name:Kowa Research Europe Ltd
    Full Title: A Double-Blind, Randomised, Dose-Ranging Study to Compare K-832 with Placebo in the treatment of Patients with Active Rheumatoid Arthritis
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    6.0 10028395 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2004-001453-28 Sponsor Protocol Number: CRFB002B2201 Start Date*: 2004-11-19
    Sponsor Name:Novartis Pharma AG
    Full Title: Open-label, Multicenter, Phase II Study Assessing the Safety of Lucentis (ranibizumab) Administered in Conjunction with Photodynamic Therapy with Visudyne in Patients with Occult or Predominantly C...
    Medical condition: Male and female patients > 50 years of age with subfoveal choroidal neovascularization (CNV) secondary to AMD.
    Disease: Version SOC Term Classification Code Term Level
    7.0 10060837 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2005-000313-35 Sponsor Protocol Number: 041210 Start Date*: 2005-04-13
    Sponsor Name:Aerovance Inc
    Full Title: A Phase I/II Study to Investigate the Efficacy and Safety of AER 002 in Cystic Fibrosis Given at 3 mg, 10 mg, and 30 mg Doses in Single then Multiple Ascending Doses and to Determine Efficacy of th...
    Medical condition: Cystic Fibrosis
    Disease: Version SOC Term Classification Code Term Level
    7.1 10011762 LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-000767-10 Sponsor Protocol Number: V82P1 Start Date*: 2004-06-29
    Sponsor Name:CHIRON
    Full Title: A Phase I/II, Single Center, Partially Observer-Blind, Controlled, Randomized Study to Explore Safety and Immunogenicity in Healthy Adult Subjects who Receive Either One Dose of Chiron Combined Men...
    Medical condition: Active immnunisation for the prevention of invasive disease caused by N. Meningitidis serogroup C and H. influenzae type b
    Disease: Version SOC Term Classification Code Term Level
    6.1 10027249 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2005-001816-27 Sponsor Protocol Number: 62202-655 Start Date*: 2005-07-28
    Sponsor Name:Clinical Data Care Spain S.L.
    Full Title: Open label randomized phase II, multicentre, pilot study to evaluate safety and efficacy of the combination of cetuximab and concomitant-boost accelerated radiotherapy followed or not by a compleme...
    Medical condition: locally advanced oropharynx squamous cell carcinoma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-001027-11 Sponsor Protocol Number: AS07/1104-001 Start Date*: 2005-06-03
    Sponsor Name:University Hospitals Coventry and Warwickshire NHS Trust
    Full Title: Diabetes in the Very Elderly Trial
    Medical condition: Type 2 Diabetes Mellitus
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-000483-77 Sponsor Protocol Number: PROPOFOL Start Date*: 2005-07-07
    Sponsor Name:Lund University, Malmö University Hospital
    Full Title: Inverkan av fraktionerad tillförsel av propofol med eller utan samtidig venstas på intensitet av lokal smärta utlöst av efterföljande intravenös injektion av propofol.
    Medical condition: Studien avser inte att studera något särskilt medicinskt tillstånd utan att klarlägga om man på patienter inför generell anestesi kan reducera den lokala smärta från injektionsområdet som idag besv...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-001217-17 Sponsor Protocol Number: Max-Planck-Institute of Psychiatry Start Date*: 2005-09-12
    Sponsor Name:Max-Planck-Institute of Psychiatry
    Full Title: Comparison of venlafaxine augmentation with lamotrigine, quetiapine, or placebo in treatment resistant depression
    Medical condition: Treatment resistant depression
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-000922-22 Sponsor Protocol Number: TA-NIC/03 Start Date*: 2006-04-18
    Sponsor Name:Xenova Ltd
    Full Title: A phase II double blind, randomised, placebo controlled, multicentre study to assess the efficacy and safety of TA-NIC in maintaining smoking cessation when given in conjunction with Nicotine Repla...
    Medical condition: Prevention of relapse in smokers who have quit.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2005-003248-75 Sponsor Protocol Number: STEMALS 01 Start Date*: 2005-08-31
    Sponsor Name:AZIENDA SANITARIA OSPEDALIERA "S. GIOVANNI BATTISTA DI TORINO"
    Full Title: PILOT STUDY ON SAFETY AND TOLERABILITY OF REPEATED MOBILIZATION PROCEDURES OF OSTEO-MEDULLARY DERIVED CELLS IN PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS
    Medical condition: SLOWING OF ALS PROGRESSION
    Disease: Version SOC Term Classification Code Term Level
    6.1 10002026 PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002650-59 Sponsor Protocol Number: SP824 Start Date*: 2005-02-03
    Sponsor Name:SCHWARZ BIOSCIENCES
    Full Title: A phase 3b, open-label, multicentre, multinational trial to assess the tolerability of switching subjects from ropinerole, pramipexole or cabergoline to the rotigotine transdermal system and its ef...
    Medical condition: Idiopathic Parkinson's disease
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-002231-92 Sponsor Protocol Number: AP23573-04-202 Start Date*: Information not available in EudraCT
    Sponsor Name:ARIAD Pharmaceuticals, Inc.
    Full Title: A Phase II Study of AP23573, an mTOR Inhibitor, in Patients with Advanced Sarcoma
    Medical condition: Metastatic and/or unresectable soft tissue or bone sarcoma (excluding GIST).
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2005-002736-10 Sponsor Protocol Number: MVPV1 Start Date*: 2006-01-20
    Sponsor Name:Royal Marsden Hospital
    Full Title: Open, Randomised Phase II Study Assessing The Toxicity And Efficacy Of Platinum-Based Chemotherapy With Vitamin Supplementation In The Treatment Of Lung Cancer
    Medical condition: Non-small cell lung cancer Small-cell lung cancer Malignant Mesothelioma (ICD classification code:C45.9)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-004283-23 Sponsor Protocol Number: Emboli Inhibition Start Date*: 2006-05-05
    Sponsor Name:South Manchester University Hospital
    Full Title: An evaluation of potential therapies to inhibit cerebral emboli in dementia
    Medical condition: Alzheimer's Disease and Vascular Dementia
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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