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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44352   clinical trials with a EudraCT protocol, of which   7379   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,352 result(s) found. Displaying page 356 of 2,218.
    EudraCT Number: 2010-021022-35 Sponsor Protocol Number: 0908125 Start Date*: 2010-10-12
    Sponsor Name:CHU de Saint-Etienne
    Full Title: Effet of curarization under general anaesthesia on eye movements in non-strabismus children
    Medical condition: Healthy volunteer who will have a surgery requiring curare administration (amygdalectomy...)
    Disease: Version SOC Term Classification Code Term Level
    12.1 10042609 Surgery LLT
    12.1 10057290 Curarization LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021039-14 Sponsor Protocol Number: S001-2010 Start Date*: 2010-08-19
    Sponsor Name:Tampere University, Faculty of Medicine, Department of Ophthalmology
    Full Title: An open-label, phase IV, pilot study, to evaluate confocal microscopic findings of cornea, ocular signs and symptoms in patients with ocular hypertension or open-angle glaucoma switching from latan...
    Medical condition: Ocular Hypertension (OH) or Open-Angle Glaucoma (OAG); primary open-angle glaucoma [POAG] or capsular glaucoma.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10030043 Ocular hypertension LLT
    12.1 10030856 Open-angle glaucoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-021221-12 Sponsor Protocol Number: UMC Utrecht Start Date*: 2011-07-11
    Sponsor Name:UMCU
    Full Title: A phase I/ II study Efficacy and safety of alpha/beta T- /CD19B-cell depleted allogeneic haematopoietic stem cells transplantation in high risk or relapsed acute leukaemia / MDS followed by an inn...
    Medical condition: Patients with high risk acute leukemia / MDS or relapse acute leukemia /MDS
    Disease: Version SOC Term Classification Code Term Level
    12.1 10066481 Hematological malignancy LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001616-57 Sponsor Protocol Number: ARD12130 Start Date*: 2011-10-05
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: A Phase 2 study of SAR245409 in patients with relapsed or refractory mantle cell lymphoma, follicular lymphoma, or chronic lymphocytic leukemia/small lymphocytic lymphoma
    Medical condition: Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    13.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10025310 Lymphoma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021520-10 Sponsor Protocol Number: D9830C00021 Start Date*: 2010-09-16
    Sponsor Name:AstraZeneca AB
    Full Title: An open, single centre, phase I study in male adolescents with asthma, aged 12 to 17 years, to assess pharmacokinetics of orally administered AZD1981 tablets 100mg twice daily for 6½ days
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    12.1 10003553 Asthma LLT
    Population Age: Adolescents, Under 18 Gender: Male
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021533-31 Sponsor Protocol Number: CRIT124D2302 Start Date*: 2011-02-08
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 40-week, randomized, double-blind, placebo-controlled, multicenter efficacy and safety study of Ritalin® LA in the treatment of adult patients with childhood-onset ADHD
    Medical condition: Adult patients with childhood-onset Attention Deficit Hyperactivity Disorder
    Disease: Version SOC Term Classification Code Term Level
    14.1 10037175 - Psychiatric disorders 10003735 Attention deficit-hyperactivity disorder LLT
    14.1 10037175 - Psychiatric disorders 10003737 Attention deficit/hyperactivity disorder NOS LLT
    14.1 10037175 - Psychiatric disorders 10003736 Attention deficit/hyperactivity disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) SE (Completed) BE (Completed) DK (Completed) NO (Completed)
    Trial results: View results
    EudraCT Number: 2010-021534-55 Sponsor Protocol Number: 72311424 Start Date*: 2010-12-16
    Sponsor Name:Luis Carlos Imaz Navarro
    Full Title: Comparación analgésica de bupivacaína, a diferentes dosis por catéter paravertebral torácico, y su implicación en la función pulmonar en pacientes intervenidos de toracotomía para cirugía de resecc...
    Medical condition: Pacientes intervenidos de toracotomía para cirugía de resección pulmonar (Thoracotomy for pulmonar resection)
    Disease: Version SOC Term Classification Code Term Level
    13 10002708 Toracotomía anterior LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-021456-25 Sponsor Protocol Number: LAT-SOP-01-2010 Start Date*: 2011-03-15
    Sponsor Name:Laboratorios SOPHIA, S.A. de C.V.
    Full Title: “ESTUDIO CLÍNICO DE SEGURIDAD PARA COMPARAR UNA SOLUCIÓN TÓPICA OFTÁLMICA DE GAAP OFTENO® (LATANOPROST AL 0.005%) FRENTE A XALATAN® (LATANOPROST AL 0.005%) COMO PRODUCTO DE REFERENCIA, EN PACIENTES...
    Medical condition: Pacientes con glaucoma primario de ángulo abierto y/o hipertensión ocular
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016953-16 Sponsor Protocol Number: FTG-AD Start Date*: 2010-07-14
    Sponsor Name:Inn-Salzach-Klinikum gGmbH
    Full Title: Depressions-Spektrums-Störung und differenzielle Effekte neuerer Antidepressiva auf die Verkehrssicherheit
    Medical condition: Spectrum of depressive diseases, ICD-10: F32.x, F33.x
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-016140-39 Sponsor Protocol Number: IDI-GAD-2009-01 Start Date*: 2010-01-19
    Sponsor Name:Institut Diagnostic per la Imatge
    Full Title: MRI in Clinically Isolated Syndromes and relapsing multiple sclerosis after single dose (0.1 mmol/kg) and cumulative dose (0.1 + 0.1 mmol/kg) of GADOVIST at 3.0T Estudio de resonancia magnética 3...
    Medical condition: Realce de contraste en resonancia magnética en pacientes con Síndrome Clínico Aislado o recaída de Esclerosis Múltiple con resonancia magnética anormal anterior después de la administración de dosi...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-021086-73 Sponsor Protocol Number: Uni-Koeln-1443 Start Date*: 2012-05-11
    Sponsor Name:University of Cologne
    Full Title: HD-R3i - A prospective, randomized, placebo-controlled, international, multicenter phase I/II trial of RAD001 (everolimus) in combination with DHAP as induction therapy in patients with relapsed or...
    Medical condition: relapsed or refractory Hodgkin Lymphoma
    Disease: Version SOC Term Classification Code Term Level
    20.0 10005329 - Blood and lymphatic system disorders 10025319 Lymphomas Hodgkin's disease HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2010-021092-89 Sponsor Protocol Number: SICOG1001 Start Date*: 2011-04-07
    Sponsor Name:SOUTHERN ITALY COOPERATIVE ONCOLOGY GROUP
    Full Title: Cisplatin and Alimta with panitumumaB for Advanced non-squamous Lung cAncer (CABALA Trial): a SICOG multicenter, phase II trial
    Medical condition: previously untreated, EGFR + (FISH), advanced, non-squamous, NSCLC
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029107 HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2010-021123-26 Sponsor Protocol Number: 03062010 Start Date*: 2010-10-29
    Sponsor Name:National Institute for Health and Welfare
    Full Title: Kaksoissokkoutettu kliininen hoitotutkimus: Rahapeliriippuvuuden hoitaminen opiaattisalpaaja naltreksonilla ja oppimismallilla
    Medical condition: Pathological gambling dependence
    Disease: Version SOC Term Classification Code Term Level
    12.1 10017657 Gambling pathological LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001769-27 Sponsor Protocol Number: CHI0465 Start Date*: 2008-09-29
    Sponsor Name:Southampton University Hospital Trust
    Full Title: Microbiological assessment of prophylactic ciprofloxacin therapy for children with cystic fibrosis during viral respiratory viral infection to prevent Pseudomonas aeruginosa colonisation – a random...
    Medical condition: Cystic Fibrosis Specifically the trial will include children aged 2-14 years with a diagnosis of cystic fibrosis and not chronically infected with pseudomonas aeruginosa in their lungs.
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2008-001774-32 Sponsor Protocol Number: 880701 Start Date*: 2008-06-04
    Sponsor Name:Baxter Innovations GmbH
    Full Title: A BLINDED PHASE I/II DOSE ESCALATION STUDY TO ASSESS SAFETY AND IMMUNOGENICITY AND INVESTIGATE THE OPTIMAL DOSE LEVEL OF A FORMALIN-TREATED, UV-INACTIVATED, VERO CELL-DERIVED ROSS RIVER VIRUS (RRV)...
    Medical condition: Vaccination against Ross River Virus Infection in healthy subjects between 18-40 years of age.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10050931 Ross river virus infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: BE (Completed) AT (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2008-001779-31 Sponsor Protocol Number: FONDAPARINUX Start Date*: 2008-05-09
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI
    Full Title: Markers of hypercoagulability and risk of death and rehospitalization in heart failure patients: a pilot study on the effects of Fondaparinux
    Medical condition: heart failure patients (III-IV NYHA)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-010434-22 Sponsor Protocol Number: CCD-0902-PR-0013 Start Date*: 2009-08-24
    Sponsor Name:Chiesi Farmaceutici S.p.A.
    Full Title: A SINGLE-DOSE, OPEN-LABEL, 2-WAY CROSS-OVER, CLINICAL PHARMACOLOGY STUDY OF CHF 1535 50/6 HFA pMDI (FIXED COMBINATION OF BECLOMETHASONE DIPROPIONATE 50µg PLUS FORMOTEROL FUMARATE 6 µg ) USING THE A...
    Medical condition: Asthmatic children, aged 5-11, with a forced expiratory volume in one second (FEV1) > 70% of predicted values.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2009-009952-18 Sponsor Protocol Number: P071222 Start Date*: 2010-01-05
    Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
    Full Title: Intérêt des inhibiteurs de l'enzyme de conversion dans l'atteinte rénale précoce des enfants drépanocytaires : Etude randomisée en double aveugle énalapril versus placebo.
    Medical condition: Atteinte rénale précoce des enfants drépanocytaires.
    Disease: Version SOC Term Classification Code Term Level
    8.1 10051051 Drépanocytose PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007177-20 Sponsor Protocol Number: Sirolimus_Liver_Tolerance Start Date*: 2009-09-07
    Sponsor Name:Hospital Clinic Barcelona
    Full Title: EFECTO DEL SIROLIMUS SOBRE LOS BIOMARCADORES RELACIONADOS CON LA TOLERANCIA EN RECEPTORES DE TRASPLANTE HEPÁTICO ESTABLES
    Medical condition: Stable liver transplant recipients identified as non-tolerant (i.e. requiring indefinite immunosuppressive therapy) on the basis of peripheral blood transcriptional biomarkers.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024716 Liver transplantation LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-007183-42 Sponsor Protocol Number: A7881006 Start Date*: 2009-03-20
    Sponsor Name:Pfizer Ltd.
    Full Title: A PHASE IIb RANDOMISED DOUBLE BLIND, PLACEBO CONTROLLED PARALLEL GROUP STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF PF-00610355 OVER 4 WEEKS IN MODERATE ASTHMATIC SUBJECTS
    Medical condition: Asthma
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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