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Clinical trials for Allergens

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44339   clinical trials with a EudraCT protocol, of which   7369   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    171 result(s) found for: Allergens. Displaying page 4 of 9.
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    EudraCT Number: 2004-001130-16 Sponsor Protocol Number: IC011RUP/4/04 Start Date*: Information not available in EudraCT
    Sponsor Name:J. URIACH & COMPAÑIA
    Full Title: 12 months long term safety and tolerability of Rupatadine 10 mg in the treatment of moderate-severe persistent allergic rhinitis.
    Medical condition: Perennial allergic rhinitis is a autoinmuno disease and its pathopshysiology is based on released of several mediators, such as histamine. The symptoms include: itchy eyes and palate, runny nose, s...
    Disease: Version SOC Term Classification Code Term Level
    6 10039094 pt
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-001521-19 Sponsor Protocol Number: MS04062004 Start Date*: 2004-09-01
    Sponsor Name:SEVAPHARMA a.s.
    Full Title: An open clinical trial on teh efficacy of H-AL pollens (Grass mixture I) administered orally and sublingually in patients with indicated allergen immunotherapy (AIT) with Type I allergy mediated by...
    Medical condition: Type I allergy to pollens mediated by IgE antibodies
    Disease:
    Population Age: Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002872-41 Sponsor Protocol Number: ELR100710 Start Date*: 2005-10-18
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A Study to Validate Key Therapeutic Targets and Biomarkers during Allergen Exposure in Subjects with Allergic Rhinitis
    Medical condition: Seasonal allergic rhinitis
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-003270-28 Sponsor Protocol Number: VB-02-DFLOP Start Date*: 2014-01-27
    Sponsor Name:Instituto de Inmunología y Alergia INMUNAL S.A..U.
    Full Title: Biological standardization of allergenic extracts of Dermatophagoides farinae and Lolium perenne. Open label. Single Center. Phase II Study.
    Medical condition: Biological standardization for allergenic extracts in patients with hipersensibility to extracts.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021428 - Immune system disorders 10001708 Allergic conditions HLGT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-000513-29 Sponsor Protocol Number: CLU-2008-001 Start Date*: 2008-09-30
    Sponsor Name:ROXALL Medizin GmbH
    Full Title: Efficacy and safety of subcutaneous cluster immunotherapy with cluster-allergoid CLUSTOID® (glutaraldehyde-polymerized allergen extract of mixtures of grass and rye allergens – Holcus lanatus, Dact...
    Medical condition: This clinical trial will evaluate the benefit of subcutaneous cluster immunotherapy with cluster-allergoid CLUSTOID® over placebo in patients with allergic rhinoconjunctivits.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002105-11 Sponsor Protocol Number: BTT-gpASIT009 Start Date*: 2015-11-10
    Sponsor Name:BioTech Tools S.A.
    Full Title: A multicenter, international, randomised, double-blind, placebo controlled study to demonstrate the clinical efficacy and safety of a subcutaneous immunotherapy with gpASIT+™ in patients with grass...
    Medical condition: Treatment of seasonal grass pollen rhinoconjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004870 10019170 Hay fever LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed) BE (Completed) CZ (Completed) ES (Completed) FR (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005450-45 Sponsor Protocol Number: P04684 Start Date*: 2006-08-30
    Sponsor Name:Schering-Plough Research Institute
    Full Title: Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Multicenter/ Multinational, Efficacy and Safety Study of Desloratadine 5 mg in the Treatment of Subjects With Allergic Rhinitis Who Mee...
    Medical condition: Persistent Allergic Rhinitis (Allergic Rhinitis)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039085 PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) PT (Completed) ES (Completed) DE (Completed) HU (Completed) SE (Completed) GR (Completed) DK (Completed) IT (Completed) BE (Completed) NL (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-003258-98 Sponsor Protocol Number: VO53.06 Start Date*: 2007-04-11
    Sponsor Name:Stallergenes S.A.
    Full Title: A randomised, double-blind, placebo-controlled, multi-national, multi-centre, Phase III study to assess the long term efficacy, carry-over effect and safety of two dosing regimens of 300 IR subling...
    Medical condition: grass pollen rhinoconjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039085 Rhinitis allergic PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: CZ (Completed) DE (Completed) SK (Completed) AT (Completed) DK (Completed) FR (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2015-004888-37 Sponsor Protocol Number: FFR111158 Start Date*: 2016-08-03
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A Pilot, Randomised, Double-blind, Placebo-controlled, Parallel-group, Multicentre Study to Evaluate the Efficacy and Safety of Once-daily Intranasal Administration of Fluticasone Furoate Nasal Spr...
    Medical condition: Irritant (non-allergic) rhinitis
    Disease:
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2006-005911-82 Sponsor Protocol Number: AL0506st Start Date*: 2007-04-02
    Sponsor Name:Allergopharma GmbH & Co. KG
    Full Title: A multicenter, placebo-controlled, double-blind study to evaluate efficacy and safety of a perennial sublingual specific immunotherapy with a solution of grass pollen allergen extract in children w...
    Medical condition: IgE-mediated allergic disease manifested as symptoms of allergic rhinitis/rhinoconjunctivitis with or without allergic bronchial asthma (GINA I und II) triggered by grass pollen allergens.
    Disease: Version SOC Term Classification Code Term Level
    18.1 10021428 - Immune system disorders 10048908 Seasonal allergy PT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2012-000594-24 Sponsor Protocol Number: 12/014/TAR Start Date*: 2012-04-19
    Sponsor Name:Royal Sussex County Hospital
    Full Title: An open study to investigate the effects of injection immunotherapy on allergen-specific T and B cell responses in adult patients with seasonal allergic rhinitis.
    Medical condition: Allergic Rhinitis due to birch or grass pollen
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038738 - Respiratory, thoracic and mediastinal disorders 10001726 Allergic rhinitis due to pollen LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-002502-34 Sponsor Protocol Number: VO42.05 Start Date*: 2005-12-05
    Sponsor Name:Stallergenes S.A.
    Full Title: A randomised, double-blind, placebo-controlled, multi-national, multi-centre, Phase III paediatric study of the efficacy and safety of one dose of sublingual immunotherapy (SLIT) administered as al...
    Medical condition: Grass Pollen Related Allergic Rhinoconjunctivitis
    Disease: Version SOC Term Classification Code Term Level
    7.0 10010744 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: EE (Prematurely Ended) DE (Completed) DK (Completed) LV (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-003454-29 Sponsor Protocol Number: CYT005-AllQbG10 04 Start Date*: 2007-10-19
    Sponsor Name:Cytos Biotechnology AG
    Full Title: Double-blind, Placebo-controlled Study to Investigate Safety, Tolerability, Immunogenicity and Clinical Efficacy of a Specific Immuotherapy Combining Allergen with CYT003-QbG10 (CYT005-AllQbG10) in...
    Medical condition: Adult patients with perennial allergic rhinoconjunctivitis due to house dust mite allergy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10063527 Allergic respiratory symptom LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-006258-16 Sponsor Protocol Number: AL0801rB Start Date*: 2008-11-19
    Sponsor Name:ALLERGOPHARMA JOACHIM GANZER KG
    Full Title: A multicentre randomised placebo-controlled double-blind clinical trial for the immunological and histological evaluation of specific immunotherapy with an aluminium hydroxide-adsorbed recombinant ...
    Medical condition: ICD classification code: J45.0 and J30.1
    Disease: Version SOC Term Classification Code Term Level
    9.1 10039085 Rhinitis allergic LLT
    9.1 10001705 Allergic asthma LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2012-004257-81 Sponsor Protocol Number: SP121PL201 Start Date*: 2012-12-10
    Sponsor Name:SmartPractice
    Full Title: Clinical Evaluation of Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral®) Dose Response Study
    Medical condition: Diagnosis of Allergic Contact Dermatitis
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004858 10056265 Allergic contact dermatitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2019-003768-31 Sponsor Protocol Number: NNF18OC0052256 Start Date*: 2019-12-05
    Sponsor Name:Lungemedicinsk Forskningsenhed
    Full Title: Effects of azithromycin treatment on anti-viral immunity in patients with asthma and COPD.
    Medical condition: COPD and asthma
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-005449-20 Sponsor Protocol Number: P04683 Start Date*: 2006-08-30
    Sponsor Name:Schering-Plough Research Institute
    Full Title: Double-Blind, Randomized, Placebo-Controlled, Parallel-Groups, Multicenter/ Multinational, Efficacy and Safety Study of Desloratadine 5 mg in the Treatment of Subjects With Allergic Rhinitis who Me...
    Medical condition: Intermittent Allergic Rhinitis (Allergic Rhinitis)
    Disease: Version SOC Term Classification Code Term Level
    8.1 10039085 PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) PT (Completed) ES (Completed) DE (Completed) HU (Completed) SE (Completed) GR (Completed) DK (Completed) IT (Completed) BE (Completed) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2020-002961-32 Sponsor Protocol Number: LP0133-1402 Start Date*: 2021-07-01
    Sponsor Name:LEO Pharma A/S
    Full Title: A phase 3 clinical trial to confirm efficacy and evaluate safety of twice-daily delgocitinib cream 20 mg/g compared with cream vehicle for a 16-week treatment period in adult subjects with moderate...
    Medical condition: Chronic Hand Eczema
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DK (Completed) BE (Completed) PL (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-004732-19 Sponsor Protocol Number: 6043-PG-PSC-206 Start Date*: 2015-07-20
    Sponsor Name:LETI Pharma GmbH
    Full Title: A Randomised, Double-Blind, Parallel Group, Multicentre Study to Assess the Efficacy and Safety of Four Concentrations of Depigoid® Phleum versus Placebo in Patients with Allergic Rhinitis and/or R...
    Medical condition: Allergic Rhinitis and / or Rhinoconjunctivitis with or without Intermittent Asthma
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004853 10001728 Allergic rhinoconjunctivitis LLT
    18.0 100000004855 10001705 Allergic asthma LLT
    18.0 100000004855 10001723 Allergic rhinitis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PL (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2012-000031-59 Sponsor Protocol Number: TT-02 Start Date*: 2012-09-12
    Sponsor Name:ALK-Abelló A/S
    Full Title: A dose-response evaluation of ALK tree AIT
    Medical condition: Subjects with a documented clinically relevant history of moderate to severe birch pollen induced allergic rhinoconjunctivitis (with or without asthma) with symptoms despite having received symptom...
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004870 10066093 Birch pollen allergy LLT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: LT (Completed) FI (Completed) NO (Completed) SE (Completed) NL (Completed) PL (Completed) DK (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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