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Clinical trials for CABG

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    252 result(s) found for: CABG. Displaying page 4 of 13.
    « Previous 1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2006-006404-11 Sponsor Protocol Number: PERFECT001(M-2006-144) Start Date*: 2008-03-19
    Sponsor Name:Miltenyi Biotec GmbH
    Full Title: INTRAMYOCARDIAL TRANSPLANTATION OF BONE MARROW STEM CELLS FOR IMPROVEMENT OF POST-INFARCT MYOCARDIAL REGENERATION IN ADDITION TO CABG SURGERY: a controlled prospective, randomized, double blinded m...
    Medical condition: Coronary artery disease after myocardial infarction with an indication for CABG surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 10007541 - Cardiac disorders 10028596 Myocardial infarction PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2018-000263-92 Sponsor Protocol Number: 17-251 Start Date*: 2018-05-28
    Sponsor Name:CHU CAEN
    Full Title: Spironolactone and perioperative atrial fibrillation occurrence in cardiac surgery patients: a multicenter randomized, double-blind study
    Medical condition: Patients > 18 years referred for elective cardiac bypass graft (CABG) surgery ± aortic valve replacement (AVR) without any systolic heart failure or any mitral surgery associated
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-010191-19 Sponsor Protocol Number: ALS-002-2009 Start Date*: 2010-03-19
    Sponsor Name:Alloksys Life Sciences BV
    Full Title: A randomized, double-blind, placebo-controlled phase IIIa study on bIAP, an anti-inflammatory moiety, in patients undergoing combined aortic valve replacement and coronary artery bypass grafting.
    Medical condition: Patients undergoing invasive cardiac surgery with prolonged perfusion time. This often is associated with potentially life-threatening inflammatory complications due to ischemic periods during surg...
    Disease: Version SOC Term Classification Code Term Level
    12.0 10057944 Combined valvular disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000024-13 Sponsor Protocol Number: aspirin v1 Start Date*: 2006-03-19
    Sponsor Name:Cardiff and Vale NHS Trust
    Full Title: Does Aggressive management with early high dose aspirin reduce the hypercoagulability of platelets following coronary artery bypass grafting?
    Medical condition: Aspirin is an antiplatelet drug that affects the ability of platelets in the blood to bind together and form clots. It is used routinely in patients with or at risk of heart disease and after surg...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-005600-28 Sponsor Protocol Number: EBI-CABG Start Date*: 2016-06-17
    Sponsor Name:Exponential Biotherapies Inc.
    Full Title: Randomized double blind placebo-controlled phase II study on the effects of EA-230 on the innate immune response following on-pump cardiac surgery
    Medical condition: Systemic inflammatory respons (SIRS) and associated acute kidney injury (AKI)
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2022-000077-57 Sponsor Protocol Number: 2021-THORANE-Pharma-001 Start Date*: 2022-06-25
    Sponsor Name:Rigshospitalet
    Full Title: Methadone versus fentanil and oxycodone for post-operative pain reduction in patients undergoing coronary artery bypass grafting and/or valve surgery – a placebo-controlled, double-blind, randomiz...
    Medical condition: We investigate the efficacy of methadonehydrochloride for reducing optoperative opioid requirements, pain scores and improving quality of recovery in patients undergoing heart surgery (i.e. corona...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10008937 Chronic ischemic heart disease, unspecified LLT
    20.0 10007541 - Cardiac disorders 10002911 Aortic valvular disorders HLT
    20.0 10007541 - Cardiac disorders 10061532 Mitral valve disease PT
    20.0 10042613 - Surgical and medical procedures 10062202 Mitral valve repair PT
    20.0 10042613 - Surgical and medical procedures 10027732 Mitral valve replacement PT
    20.0 10042613 - Surgical and medical procedures 10002916 Aortic valve replacement PT
    20.0 10042613 - Surgical and medical procedures 10061652 Aortic valve repair PT
    21.1 10042613 - Surgical and medical procedures 10011077 Coronary artery bypass PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2017-001754-33 Sponsor Protocol Number: SDAT-IRC Start Date*: 2018-10-16
    Sponsor Name:UNIVERSITÀ CAMPUS BIO-MEDICO DI ROMA
    Full Title: Single versus Dual Antiplatelet Therapy in patients with Incomplete Revascularization after Coronary artery bypass graft surgery
    Medical condition: in patients with Incomplete Revascularization after Coronary artery bypass graft surgery
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10032492 Other specified acute and subacute form of ischemic heart disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2019-003244-79 Sponsor Protocol Number: 20603 Start Date*: 2020-02-03
    Sponsor Name:Bayer AG
    Full Title: Multicenter, randomized, placebo controlled, double-blind, parallel group, dose-finding Phase 2 study to evaluate the efficacy and safety of BAY 2433334 in patients following an acute myocardial in...
    Medical condition: Acute Myocardial Infarction
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10064939 Cardiovascular event prophylaxis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) BE (Completed) HU (Completed) NL (Completed) DE (Completed) AT (Completed) ES (Completed) SE (Completed) PL (Completed) GB (GB - no longer in EU/EEA) IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003630-16 Sponsor Protocol Number: GEIDENo.D00112 Start Date*: 2013-04-10
    Sponsor Name:German Heart Centre Munich, Department of
    Full Title: A Randomized, Parallel Group, Double-Blind Study of Ticagrelor Compared with Aspirin for Prevention of Vascular Events in Patients Undergoing Coronary Artery Bypass Graft Operation TiCAB– Ticagrelo...
    Medical condition: Ticagrelor Compared with Aspirin for Prevention of Vascular Events in Patients Undergoing Coronary Artery Bypass Graft Operation
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004866 10003601 Atherosclerosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) AT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-002076-14 Sponsor Protocol Number: EPICSstudy Start Date*: 2014-05-12
    Sponsor Name:
    Full Title: Pre-operative treatment with Erythropoietin and iron supplement for prevention of perioperative blood transfusion in cardiac surgery
    Medical condition: Patients (male and female) scheduled for coronary artery bypass grafting surgery (CABG) or single Aortic Valve replacement (AVR) on conventional cardiopulmonary bypass.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-003278-15 Sponsor Protocol Number: AGO/2017/005 Start Date*: 2017-12-14
    Sponsor Name:Ghent University Hospital
    Full Title: Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting
    Medical condition: Secondary wound hyperalgesia Persistent Pain
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2015-000233-73 Sponsor Protocol Number: HCQvJan11 Start Date*: 2016-01-05
    Sponsor Name:Helsinki University Central Hospital
    Full Title: HYDROXYCHLOROQUINE IN ACUTE CORONARY SYNDROME: PREVENTION OF RECURRENT CARDIOVASCULAR EVENTS
    Medical condition: Cardiovascular disease
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-002653-31 Sponsor Protocol Number: VF20040171 Start Date*: 2004-11-25
    Sponsor Name:Odense University hospital
    Full Title: CAPHI. Profylactic effect of Ca2+ sensitizer versus phosphodiesterase inhibitor infusion at CAGB patients with preoperative low ejection fraction. A prospective randomised clinical trial.
    Medical condition: Perioperative use of Milrinon to CAGB patients has shown to reduce postoperative complications. Levosimendan improves cardiac performance without interfering with the calcium turnover and there by ...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-005526-22 Sponsor Protocol Number: V4 Start Date*: 2012-05-14
    Sponsor Name:Medizinische Universität Wien
    Full Title: Tissue concentration of cefazolin and linezolid in sternal spongiosa in elective coronary artery bypass grafting: an in-vivo microdialysis study
    Medical condition: perioperative antibiotic prophylaxis during coronary artery bypass grafting
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10036894 Prophylactic antibiotic therapy LLT
    14.1 10042613 - Surgical and medical procedures 10011077 Coronary artery bypass PT
    14.1 10042613 - Surgical and medical procedures 10064736 Antibiotic prophylaxis PT
    14.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-004565-14 Sponsor Protocol Number: 20170625 Start Date*: 2019-09-13
    Sponsor Name:Amgen Inc.
    Full Title: A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardia...
    Medical condition: Dyslipidemia
    Disease: Version SOC Term Classification Code Term Level
    21.0 100000004861 10058110 Dyslipidemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned) NL (Trial now transitioned) GB (GB - no longer in EU/EEA) SE (Trial now transitioned) HU (Trial now transitioned) DK (Trial now transitioned) DE (Trial now transitioned) PL (Trial now transitioned) BG (Trial now transitioned) ES (Ongoing) PT (Trial now transitioned) FI (Trial now transitioned) AT (Trial now transitioned) LT (Trial now transitioned) LV (Trial now transitioned) EE (Trial now transitioned) SK (Trial now transitioned) GR (Trial now transitioned) IT (Trial now transitioned) RO (Trial now transitioned) IS (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2006-005757-30 Sponsor Protocol Number: MIRACL IN CABG Start Date*: 2007-07-30
    Sponsor Name:AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI
    Full Title: MIRACL IN CABG - Statins in cardiac surgery. Effect of doses on inflammatory response and early results
    Medical condition: Pts with coronary disease undergoing coronary artery bypass graft surgery.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028600 Myocardial ischaemia LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2021-005032-30 Sponsor Protocol Number: 2021-PDNO-003 Start Date*: 2022-05-16
    Sponsor Name:Attgeno AB
    Full Title: An open-label, multicenter study to evaluate the DOSE, efficacy, safety and tolerability of PDNO (Nitrosooxypropanol) infusion in patients with pulmonary hypertension after cardiopulmonary bypass (...
    Medical condition: Acute Pulmonary Hypertension
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004855 10037401 Pulmonary hypertensions HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-013957-13 Sponsor Protocol Number: 020173 Start Date*: 2009-09-21
    Sponsor Name:Helsinki University Central Hospital
    Full Title: The effect of levosimendan on blood coagulation after cardiac surgery.
    Medical condition: Sepelvaltimotauti I20.0 Sydämen vajaatoiminta I50.0
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2020-002752-20 Sponsor Protocol Number: LAN_POAF_01 Start Date*: 2020-12-17
    Sponsor Name:Medical University of Vienna
    Full Title: A prospective, randomized, double- blind, placebo- controlled study to evaluate the efficacy of Landiolol hydrochloride for prevention of atrial fibrillation in patients undergoing cardiac surgery
    Medical condition: Perioperative atrial fibrillation (POAF) is the most common arryhthmia after cardiac surgery with incidences ranging from 20% to 40%, depending on various patient's risk factors and the type of sur...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10003658 Atrial fibrillation PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Ongoing)
    Trial results: View results
    EudraCT Number: 2021-005618-32 Sponsor Protocol Number: 2021-HJEPharma-002 Start Date*: 2022-06-29
    Sponsor Name:Rigshospitalet
    Full Title: Dexamethasone, olanzapine, flow-targeted versus pressure-targeted hemodynamic management, and low tidal volume ventilation in patients undergoing on-pump cardiac surgery – a multifactorial design r...
    Medical condition: We investigate the efficacy of two pharmaceutical interventions for reducing mortality and organ damage, and shortening length of hospital stay in patients undergoing heart surgery (i.e. coronary a...
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10008937 Chronic ischemic heart disease, unspecified LLT
    21.1 10042613 - Surgical and medical procedures 10061994 Heart valve operation PT
    20.0 10007541 - Cardiac disorders 10011085 Ischaemic coronary artery disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Trial now transitioned)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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