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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,380 result(s) found. Displaying page 420 of 2,219.
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    EudraCT Number: 2005-004605-29 Sponsor Protocol Number: ML19537 Start Date*: 2006-05-09
    Sponsor Name:ROCHE
    Full Title: A Phase IIIb Study of Tarceva (Erlotinib) in patients with locally advanced, unresectable or metastatic pancreatic cancer
    Medical condition: Locally advanced, unresectable or metastatic pancreatic cancer (adenocarcinoma)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033610 Pancreatic carcinoma metastatic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-005841-13 Sponsor Protocol Number: 65705 Start Date*: 2007-01-25
    Sponsor Name:Gedeon Richter Plc
    Full Title: Multicenter, open-label study to investigate the efficacy and safety of Cavinton Forte (vinpocetine) tablet in patients with mild cognitive impairment (MCI).
    Medical condition: Mild cognitive impairment
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009846 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2006-005855-14 Sponsor Protocol Number: C2L-OCT-01 PR-301 Start Date*: 2007-02-22
    Sponsor Name:Ambrilia Biopharma Inc.
    Full Title: OPEN LABEL, RANDOMIZED STUDY COMPARING THE BIOLOGICAL EFFICACY AND SAFETY OF A NEW PROLONGED RELEASE FORMULATION OF OCTREOTIDE ACETATE, C2L-OCT-01 PR, 30 MG ADMINISTERED INTRA MUSCULARLY EVERY 42 D...
    Medical condition: Acromegaly
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) SK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-005891-41 Sponsor Protocol Number: 109509 Start Date*: Information not available in EudraCT
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase IIIb, observer-blind, controlled study to assess the safety, reactogenicity and immunogenicity of GlaxoSmithKline (GSK) Biologicals’ 10-valent pneumococcal conjugate vaccine or Prevenar whe...
    Medical condition: Booster vaccination against Streptococcus pneumoniae or Haemophilus influenzae in healthy infants 12 to 18 months of age who were previously primed with three doses of pneumococcal conjugate vaccin...
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: PL (Ongoing)
    Trial results: View results
    EudraCT Number: 2005-002009-22 Sponsor Protocol Number: Inoc 04/03/02 Start Date*: 2006-01-19
    Sponsor Name:VALEAS
    Full Title: CTi-Inoc Study. Compliance to the Inhalatory Therapy - Inoc . Nitric oxide in exhaled air as a marker for monitoring the compliance of therapy with steroid inhalers in asthmatic patients Pilot st...
    Medical condition: Antiasthamatic desease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003553 Asthma LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-003298-10 Sponsor Protocol Number: C0524T08 Start Date*: 2006-06-07
    Sponsor Name:Centocor BV
    Full Title: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Golimumab, a Fully Human Anti-TNFalfa Monoclonal Antibody, Administered Subcutaneously in Subjects with Active Psoriatic Arthritis
    Medical condition: Psoriatic Arthritis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) HU (Prematurely Ended) GB (Completed) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2004-000876-14 Sponsor Protocol Number: P030089-01 Start Date*: 2005-01-31
    Sponsor Name:FERRER INTERNACIONAL, S.A.
    Full Title: A multicentre, multinational, parallel, randomised, double blind clinical trial, to evaluate the non-inferiority of Prolonged Release Torasemide (PR) versus Immediate Release Torasemide (IR) in pat...
    Medical condition: MILD TO MODERATE ARTERIAL HYPERTENSION
    Disease: Version SOC Term Classification Code Term Level
    LLT 10020772 Hype
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-002880-26 Sponsor Protocol Number: AI424-128 Start Date*: 2005-04-06
    Sponsor Name:Bristol-Myers Squibb International Corporation
    Full Title: A Phase IV, Multi-center, Cross-sectional study to evaluate the I50L substitution among subjects experiencing virologic failure on a HAART regimen containing atazanavir (ATV) Protocol: version 2.0...
    Medical condition: Subjects experiencing virologic failure after a HAART regimen containing ATV
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed) DE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-002889-38 Sponsor Protocol Number: OV-WV03 Start Date*: 2004-12-16
    Sponsor Name:OmniVision GmbH
    Full Title: Randomisierte, kontrollierte, doppelblinde klinische Prüfung zur Untersuchung der Wirksamkeit und Verträglichkeit von Novesine® 0,4% Augentropfen im Vergleich zur Augentropfengrundlage bei zur Tono...
    Medical condition:
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2004-002899-42 Sponsor Protocol Number: E-L 001 Start Date*: 2004-12-15
    Sponsor Name:Dept of Paediatric Anaesthesia, Karolinska University Hospital-Solna
    Full Title: Etomidate-Lipuro vs. Diprivan-Propofol with added lignocaine: incidence of injection pain in association with induction of anaesthesia in children.
    Medical condition: Any child who is to be anaesthetised for a surgical intervention on an out-patient basis. No specific diagnosis is applicable.
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-004146-40 Sponsor Protocol Number: LEV Start Date*: 2005-03-10
    Sponsor Name:ISTITUTI FISIOTERAPICI OSPITALIERI
    Full Title: pILOT STUDY TO EVALUATE QUALITY OF LIFE, SEIZURES CONTROL AND SIDE EFFECTS IN PATIENTS WITH BRAIN TUMORS AND EPILEPSY TREATED WITH LEVETIRACETAM IN MONOTHERAPY
    Medical condition: TREATMENT OF EPILEPSY IN PATIENTS WITH BRAIN TUMORS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10015037 Epilepsy LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2005-005130-12 Sponsor Protocol Number: 6096A1-007 Start Date*: 2006-08-03
    Sponsor Name:Wyeth Research Division of Wyeth Pharmaceuticals Inc
    Full Title: A Phase 3, Randomized, Active-Controlled, Double-blind Trial Evaluating the Safety, Tolerability, and Immunogenicity of a 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants Given With Rout...
    Medical condition: Healthy infants
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-005778-63 Sponsor Protocol Number: NB1-STI571 Start Date*: 2005-12-20
    Sponsor Name:ISTITUTO GIANNINA GASLINI
    Full Title: Phase II study of Glivec (imatinib mesylate) in patients with advanced neuroblastoma
    Medical condition: High risk Neuroblastoma
    Disease: Version SOC Term Classification Code Term Level
    6.1 10029260 PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004071-34 Sponsor Protocol Number: PRG-Opioid-06-/03 Start Date*: 2009-01-14
    Sponsor Name:Queen Mary, University of London (QMUL)
    Full Title: A single centre, parallel group, pilot study to investigate the effect of opioids on immunomarkers using gene expression profiling.
    Medical condition: This study is not looking at any disease process
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2006-004102-13 Sponsor Protocol Number: AcadMed CTU210406 Start Date*: 2006-10-16
    Sponsor Name:Hull and east yorkshire Hospitals Trust
    Full Title: An 8 week, non-selected, cohort, study to investigate whether the treatment of reflux induced cough alters associated bronchial hyperresponsiveness.
    Medical condition: Bronchial hyper-responsiveness in relation to reflux associated chronic cough
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011233 Coughing and associated symptoms HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-004106-87 Sponsor Protocol Number: CAS CVVH Start Date*: 2007-10-23
    Sponsor Name:Meical University, Dpt. Internal Medicine, Div. of General Internal Medicine
    Full Title: CLINICAL PHARMACOKINETICS OF CASPOFUNGIN IN CRITICALLY ILL PATIENTS DURING CONTINUOUS VENO-VENOUS HEMOFILTRATION
    Medical condition: Plasma concentrations of Caspofungin will be measured in patients requiring treatment with Cancidas (Caspofungin) and continuous veno-venous hemofiltration
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2006-004111-22 Sponsor Protocol Number: CSOM230B2305 Start Date*: 2007-01-05
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A randomized, double-blind study to assess the safety and efficacy of different dose levels of Pasireotide (SOM230) s.c. over a 6 month treatment period in patients with de novo, persistent or recu...
    Medical condition: Cushing’s disease is rare disease that is caused by an adrenocorticotropic hormone (ACTH) secreting pituitary adenoma. The elevated ACTH secreted by these tumors stimulates the adrenal glands to pr...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10011651 Cushing's disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended) BE (Completed) IT (Completed) FI (Completed) FR (Completed) DE (Completed) PT (Completed) GR (Completed) GB (Completed) HU (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2006-004128-35 Sponsor Protocol Number: CAEB071A2207 Start Date*: 2007-03-06
    Sponsor Name:Novartis Pharma Services AG
    Full Title: A 12-month open-label, randomized, multicenter, sequential cohort, dose finding study to evaluate the efficacy, safety and tolerability of oral AEB071 versus tacrolimus® in combination with myforti...
    Medical condition: Evaluation of the efficacy and safety of AEB071 in de novo CNI free regimen for prevention of rejection in solid organ transplantation. Combination of AEB071 with a well established, effective ad...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) DE (Prematurely Ended) GB (Prematurely Ended) BE (Completed) ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001537-15 Sponsor Protocol Number: CSTI571BDE28 Start Date*: 2006-03-14
    Sponsor Name:Novartis Pharma GmbH
    Full Title: Open-label trial of imatinib mesylate (Glivec, formerly known as STI571) in combination with vinorelbine (Navelbine) for patients with advanced breast carcinoma
    Medical condition: carcinoma breast
    Disease: Version SOC Term Classification Code Term Level
    M15 10007305 LLT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2005-001539-31 Sponsor Protocol Number: FE999905 CS002 Start Date*: 2005-09-16
    Sponsor Name:Ferring Pharmaceuticals A/S
    Full Title: An Open-label, Multi-centre, Phase III Study of Local Tolerability of Zomacton 10 mg (Recombinant Somatropin) administered by ZomaJet Vision X
    Medical condition: Zomacton is indicated for the long term treatment of children who have growth failure due to inadequate secretion of growth hormone and for the long-term treatment of growth retardation due to Turn...
    Disease:
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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