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Clinical trials for Surgery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44344   clinical trials with a EudraCT protocol, of which   7373   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    5,833 result(s) found for: Surgery. Displaying page 7 of 292.
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    EudraCT Number: 2018-001305-82 Sponsor Protocol Number: IC3627/18 Start Date*: 2019-05-16
    Sponsor Name:Laura Perelló Moreno
    Full Title: Study on the advantages of local post-operative infiltration in forefoot surgery.
    Medical condition: management of postoperative pain in ambulatory foot surgery that allows the realization of immediate rehabilitation and better functional results and personal satisfaction
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006163-22 Sponsor Protocol Number: PK-VIT-D Start Date*: 2012-04-20
    Sponsor Name:Fundació Clínic per a la Recerca Biomèdica
    Full Title: Study to evaluate the pharmacokinetic of vitamin D (cholecalciferol) in patients with obesity after bariatric surgery in vitamin D deficiency and after normalization
    Medical condition: Obese patients after bariatric surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10059610 Obesity surgery PT
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002672-25 Sponsor Protocol Number: STR001-201 Start Date*: 2015-11-18
    Sponsor Name:Strekin AG
    Full Title: A Phase II multicenter, placebo-controlled, proof-of-concept study evaluating the safety, and efficacy of intratympanic STR001 thermogel to preserve residual hearing in adults undergoing cochlear ...
    Medical condition: Prevention of Hearing Loss after Cochlear Implant Surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) ES (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2017-001646-10 Sponsor Protocol Number: ANIMAL-523-2014-2569 Start Date*: 2017-06-22
    Sponsor Name:Uppsala University Hospital
    Full Title: Anesthesia Induced Hormonal Oliguria Trial
    Medical condition: Anaesthesia in adult patients undergoing general surgery
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2018-004852-39 Sponsor Protocol Number: ORTEGA-PHRCK-2017 Start Date*: 2019-03-12
    Sponsor Name:CHU Dijon Bourgogne
    Full Title: Benefit of a flash dose of corticosteroids in digestive surgical oncology: a randomized, double blind, placebo-controlled trial
    Medical condition:
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2022-003262-20 Sponsor Protocol Number: PROPHYLOXITIN Start Date*: 2023-02-23
    Sponsor Name:CHU de Poitiers
    Full Title: Intermittent cefoxitin administration versus loading bolus followed by continuous infusion for the prevention of surgical site infection in colorectal surgery: a multicentre, double-blind, randomiz...
    Medical condition: colorectal surgery
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2020-003407-34 Sponsor Protocol Number: pre-CIN Start Date*: 2021-06-01
    Sponsor Name:Oslo University Hospital
    Full Title: A randomized clinical three-arm trial comparing inflammation and cystoid macular edema for the medication regimens preoperative and postoperative topical NSAIDs to only postoperative topical NSAIDs...
    Medical condition: Cataract surgery, and the medical treatment is anti-inflammatory eye drops to treat (and prevent) intraocular inflammation and development og cystoid macular edema.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NO (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2011-005534-19 Sponsor Protocol Number: FRIA_FATSURG_1 Start Date*: 2012-01-31
    Sponsor Name:Vrije Universiteit Brussel
    Full Title: The effect of peri-operative anti-inflammatory treatment on postoperative muscle weakness and muscle fatigue in elderly elective surgery patients: a double blinded randomized placebo-controlled trial.
    Medical condition: Post-operative muscle weakness, fatigue and inflammation.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2022-001252-41 Sponsor Protocol Number: NA Start Date*: 2022-07-08
    Sponsor Name:CHU de Liège
    Full Title: Preventing postoperative anaemia in total knee arthroplasty and impact of intravenous iron supplementation on postoperative functional recovery : a randomized clinical trial
    Medical condition: Total Knee Arthroplasty
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2020-003300-14 Sponsor Protocol Number: 74719 Start Date*: 2020-10-07
    Sponsor Name:Department of Cardiothoracic Surgery, Aalborg Universityhospital
    Full Title: Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery: a Randomized Controlled Pilot Trial
    Medical condition: Post Thoracotomy Pain Syndrome (PTPS)
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2013-002217-36 Sponsor Protocol Number: 20130021 Start Date*: 2013-07-04
    Sponsor Name:Dept. of Anaesthesiology, Odense University Hospital
    Full Title: Crystalloid versus colloid for goal directed haemodynamic optimisation in major abdominal cancer surgery.
    Medical condition: Patients undergoing surgery for pancreatic, gastric or esophageal cancer.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10068093 Gastrointestinal surgery PT
    20.0 10042613 - Surgical and medical procedures 10011508 Crystalloid colloid fluid replacement LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2012-005701-43 Sponsor Protocol Number: PROP-001-CP3 Start Date*: 2013-04-11
    Sponsor Name:Fresenius Kabi Deutschland GmbH
    Full Title: Therapeutic Equivalence Study of Propofol Using Target-Controlled Infusion of Propofol 2% (20 mg/mL) MCT Fresenius Compared with Diprivan® 20 mg/mL (AstraZeneca) in Patients Undergoing Elective Sur...
    Medical condition: Elective minor Surgery
    Disease: Version SOC Term Classification Code Term Level
    18.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2008-001124-31 Sponsor Protocol Number: VDM 02/08 Start Date*: 2008-04-11
    Sponsor Name:UZ Leuven
    Full Title: Can the use of statin reduce the incidence of atrial flutter after major non-cardiac thoracic surgery ? A randomised double-blind study.
    Medical condition: Prevention of atrial flutter after major non-cardiac thoracic surgery.
    Disease:
    Population Age: Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-002348-26 Sponsor Protocol Number: HUS-PERFECT Start Date*: 2020-02-18
    Sponsor Name:Helsinki University Hospital
    Full Title: Role of delay and antibiotics on PERForation rate while waiting appendECTomy – Randomized non-inferiority trial (PERFECT)
    Medical condition: Acute appendicitis
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Completed) NO (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-005169-33 Sponsor Protocol Number: CLEAN2 Start Date*: 2018-02-23
    Sponsor Name:CHU DE POITIERS
    Full Title: An open label, multicenter, randomized trial of 2% chlorhexidine-70% isopropanol vs 5% povidone iodine-69% ethanol for skin antisepsis in reducing surgical-site infection after cardiac surgery
    Medical condition: surgery of the heart (valve, coronary or combined surgery) or of the aorta via a median sternotomy
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004865 10048935 Open heart surgery LLT
    20.0 100000004865 10049052 Aortic surgery NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2016-004446-29 Sponsor Protocol Number: LIBERAL-Trial Start Date*: 2017-10-30
    Sponsor Name:University Hospital Wuerzburg, Institution under public law, represented by the Medical Director
    Full Title: Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients
    Medical condition: Elderly patients (>= 70 years) undergoing intermediate- or high-risk non-cardiac surgery
    Disease: Version SOC Term Classification Code Term Level
    27.0 10022117 - Injury, poisoning and procedural complications 10048861 Anaemia postoperative PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005155-27 Sponsor Protocol Number: KCT09/2015-SeptaNazal-Double Start Date*: 2017-02-22
    Sponsor Name:Krka, d.d., Novo mesto
    Full Title: Comparison of the efficacy and safety of the fixed-dose combination of xylometazoline and dexpanthenol in SeptaNazal® and xylometazoline in nasal congestion in patients after surgery in the nose an...
    Medical condition: Nasal congestion in patients after nasal surgery or nasal cavities surgery and in patients with acute rhinitis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004855 10028736 Nasal congestion and inflammations HLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SI (Completed) HR (Completed)
    Trial results: View results
    EudraCT Number: 2010-019427-58 Sponsor Protocol Number: 400-10-001 Start Date*: 2010-09-08
    Sponsor Name:Omrix Biopharmaceuticals Ltd
    Full Title: A Phase III Randomized, Controlled, Superiority Study Evaluating the Fibrin Pad Versus Standard of Care Treatment in Controlling Parenchymal Bleeding During Elective Hepatic Surgery
    Medical condition: Subjects undergoing elective, open, hepatic surgery during which a resection plane is created and wherein an appropriate Target Bleeding Site is identified.
    Disease: Version SOC Term Classification Code Term Level
    12.1 10068093 Gastrointestinal surgery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-005775-16 Sponsor Protocol Number: SUBLIME1 Start Date*: 2012-06-19
    Sponsor Name:Research and Development Department
    Full Title: A randomised, double blind, placebo-controlled trial of continuous subpectoral local anaesthetic infusion for pain and shoulder function following mastectomy.
    Medical condition: Post-operative pain following mastectomy surgery
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10024758 Local anaesthesia PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-003638-10 Sponsor Protocol Number: 2016_37 Start Date*: Information not available in EudraCT
    Sponsor Name:CHRU LILLE
    Full Title: INTRANASAL CLONIDINE PREDICTION IN PEDIATRIC SURGERY: RANDOMIZED STUDY AGAINST PLACEBO
    Medical condition: intra-nasal premedication instead of oral, intravenous or no premedication.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10042613 - Surgical and medical procedures 10042609 Surgery PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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