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Clinical trials for Type 2 diabetes

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44380   clinical trials with a EudraCT protocol, of which   7392   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    2,113 result(s) found for: Type 2 diabetes. Displaying page 7 of 106.
    EudraCT Number: 2011-005806-32 Sponsor Protocol Number: SAN-LTM-001 Start Date*: 2011-12-21
    Sponsor Name:ikfe GmbH
    Full Title: Clinical Study to Collect Clinical Data Sets for Development of Insulin Glargine Titration Algorithms
    Medical condition: Type 2 diabetes mellitus receiving BOT Therapy or insulin therapy only
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-006573-24 Sponsor Protocol Number: Glargine and EPC Start Date*: 2007-07-11
    Sponsor Name:University Hospital of Heidelberg
    Full Title: Prospective influence of bedtime insulin glargine on mobilization and function of endothelial progenitor cells in patients with type 2 diabetes: a partially double-blind, randomized, three-arm unic...
    Medical condition: The medical disease that will be investigated is type 2, diabetes mellitus. The patients who will be investigated are between 35 and 70 years old and on oral antidiabetic therapy.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-016244-39 Sponsor Protocol Number: 1245.28 Start Date*: 2010-10-18
    Sponsor Name:Boehringer Ingelheim B.V.
    Full Title: A phase III randomised, double-blind, active-controlled parallel group efficacy and safety study of BI 10773 compared to glimepiride administered orally during 104 weeks in patients with type 2 dia...
    Medical condition: Type 2 diabetes mellitus pre-treated with metformin
    Disease: Version SOC Term Classification Code Term Level
    12.1 10067585 Type 2 diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) NO (Completed) FI (Completed) SE (Completed) IT (Completed) ES (Completed) GB (Completed) PT (Completed) CZ (Completed) AT (Completed)
    Trial results: View results
    EudraCT Number: 2008-006215-20 Sponsor Protocol Number: 0941-018 Start Date*: 2009-01-27
    Sponsor Name:Merck & Co., Inc.
    Full Title: A Phase IIa, Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Trial of MK-0941 in Patients with Type 2 Diabetes Mellitus with Inadequate Glycemic Control on Insulin
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DK (Completed) SE (Completed) FI (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-005886-36 Sponsor Protocol Number: EFC6016 Start Date*: 2008-07-03
    Sponsor Name:Sanofi -Aventis Recherche & De'veloppement
    Full Title: A randomized, double-blind, placebo-controlled, 2-arm parallel-group, multicenter study with a 24-week main treatment period and an extension assessing the efficacy and safety of AVE0010 in patient...
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed) DE (Completed) FR (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-005225-40 Sponsor Protocol Number: MB102-091 Start Date*: 2013-05-27
    Sponsor Name:Bristol-Myers Squibb Company
    Full Title: A Randomized, Multi-Center, Parallel Group, Single-Dose, Pharmacokinetics and Pharmacodynamics Study of Dapagliflozin in Children and Adolescents Aged 10 to 17 Years with Type 2 Diabetes Mellitus
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    14.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2005-002907-18 Sponsor Protocol Number: BM18248 Start Date*: 2005-12-19
    Sponsor Name:F. Hoffmann-La Roche Ltd
    Full Title: A multi-center phase 2 randomized, double-blind, placebo-controlled dose-ranging study to determine the efficacy, safety, tolerability and pharmacokinetics of RO4389620 in patients with type 2 diab...
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    7 10012613 low
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed)
    Trial results: View results
    EudraCT Number: 2007-004585-40 Sponsor Protocol Number: 1218.20 Start Date*: 2008-01-25
    Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG
    Full Title: A randomised, double-blind, active-controlled parallel group efficacy and safety study of BI 1356 (5.0 mg, administered orally once daily) compared to glimepiride (1 to 4 mg once daily) over two ye...
    Medical condition: Patients with type 2 diabetes.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) IE (Completed) FR (Completed) SE (Completed) NL (Completed) GB (Completed) DK (Completed) HU (Completed) IT (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2008-000300-89 Sponsor Protocol Number: DSSita-01 Start Date*: 2008-05-07
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust
    Full Title: The effects of sitagliptin (Januvia) on myocardial performance in patients with coronary artery disease and diabetes
    Medical condition: coronary artery disease and type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011085 Ischaemic coronary artery disorders HLT
    9.1 10012613 Diabetes mellitus non-insulin-dependent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-006085-15 Sponsor Protocol Number: VIAjectTM-09J Start Date*: 2008-03-14
    Sponsor Name:Biodel Inc.
    Full Title: An Open Label, Multi-Center, Follow-on Study Examining the Long- Term Safety and Efficacy of Insulin VIAject™ in Subjects with Type 2 Diabetes Mellitus
    Medical condition: Diabetes Mellitus Type 2
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012663-34 Sponsor Protocol Number: PHX1149-PROT402 Start Date*: 2010-04-07
    Sponsor Name:Phenomix Corporation
    Full Title: A Phase 3, Randomized, Double-Blind, Active-Controlled, Multi-Center Extension Study to Evaluate Safety and Efficacy of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medicat...
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    12.1 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2008-002500-26 Sponsor Protocol Number: EFC10231 Start Date*: 2008-10-13
    Sponsor Name:Sanofi-Aventis Recherche & Développement
    Full Title: A multicenter, double blind, placebo controlled randomized study of the efficacy and safety of two rimonabant/metformin combinations for reducing A1C in the treatment of patients with type 2 diabet...
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    11.0 10045242 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2013-000022-63 Sponsor Protocol Number: 1-10-72-393-12 Start Date*: 2013-03-15
    Sponsor Name:Aarhus University
    Full Title: Acyl and desacyl ghrelin: The Yin and Yang of glucose homeostasis and insulin sensitivity? -Acute metabolic effects of desacyl ghrelin in insulin resistant patients
    Medical condition: Type 2 diabetes mellitus
    Disease: Version SOC Term Classification Code Term Level
    16.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults Gender: Male
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2006-002847-96 Sponsor Protocol Number: DRI6012 Start Date*: Information not available in EudraCT
    Sponsor Name:Sanofi aventis US Inc.
    Full Title: A 13-week Multinational, Randomized, Double-Blind, Placebo-Controlled, Dose-Response Trial Assessing the Safety, Tolerability and Efficacy of AVE0010 in Metformin-Treated Subjects with Type 2 Diabe...
    Medical condition: The current study is designed to confirm the already observed clinically meaningful pharmacodynamic effect of AVE0010 on glycemic control, as measured by HbA1c, and to determine the clinically rele...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10012613 Diabetes mellitus non-insulin-dependent LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BG (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-005881-11 Sponsor Protocol Number: EFC6015 Start Date*: 2008-07-18
    Sponsor Name:Sanofi-Aventis Recherche&Développement
    Full Title: A randomized, double-blind, placebo-controlled, 2-arm parallel-group, multicenter 24-week study followed by an extension assessing the efficacy and safety of AVE0010 on top of a sulfonylurea in pat...
    Medical condition: Type II Diabetes
    Disease: Version SOC Term Classification Code Term Level
    10.1 10067585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) CZ (Completed) NL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2007-005884-92 Sponsor Protocol Number: EFC6017 Start Date*: 2009-03-30
    Sponsor Name:Sanofi-Aventis Recherche & Développement
    Full Title: A randomized, double-blind, placebo-controlled, 2-arm parallel-group, multicenter study with a 24-week main treatment period and an extension assessing the efficacy and safety of AVE0010 on top of ...
    Medical condition: Type II diabetes
    Disease: Version SOC Term Classification Code Term Level
    10.1 10067585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) FR (Completed) DE (Completed) GR (Completed)
    Trial results: View results
    EudraCT Number: 2010-023770-39 Sponsor Protocol Number: EFC11629 Start Date*: 2011-10-28
    Sponsor Name:sanofi-aventis recherche & développement
    Full Title: 6-Month, Multicenter, Randomized, Open-label, Parallel-group Study Comparing the Efficacy and Safety of a New Formulation of Insulin glargine and Lantus® both in combination with oral antihyperglyc...
    Medical condition: Type 2 Diabetes Mellitus
    Disease: Version SOC Term Classification Code Term Level
    16.0 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) PT (Completed) ES (Completed) HU (Completed) FI (Completed)
    Trial results: View results
    EudraCT Number: 2007-005887-29 Sponsor Protocol Number: EFC6018 Start Date*: 2008-04-30
    Sponsor Name:Sanofi-Aventis Recherche & Développement
    Full Title: A randomized, double-blind, placebo-controlled, parallel-group, multicenter 12-week study assessing the efficacy and safety of AVE0010 in patients with type 2 diabetes not treated with antidiabetic...
    Medical condition: Type II diabetes
    Disease: Version SOC Term Classification Code Term Level
    10.1 10067585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2016-001233-27 Sponsor Protocol Number: PI2016_843_0008 Start Date*: 2016-11-03
    Sponsor Name:CHU Amiens Picardie
    Full Title: Efficacity and safety of metformin extended release (XR) in diabetic patients with CKD in stages 1 to 3 (METXR/CKD)
    Medical condition: type 2 diabetes
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2021-005891-21 Sponsor Protocol Number: I8H-MC-BDCX Start Date*: 2022-08-04
    Sponsor Name:Eli Lilly and Company
    Full Title: A Phase 3, Parallel-Design, Open-Label, Randomized Control Study to Evaluate the Efficacy and Safety of LY3209590 as a Weekly Basal Insulin Compared to Insulin Degludec in Insulin Naïve Adults with...
    Medical condition:
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004861 10045242 Type II diabetes mellitus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GR (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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