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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44341   clinical trials with a EudraCT protocol, of which   7370   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,341 result(s) found. Displaying page 71 of 2,218.
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    EudraCT Number: 2007-007591-42 Sponsor Protocol Number: SPON416-07(WCTU011) Start Date*: 2009-01-14
    Sponsor Name:Cardiff University
    Full Title: A Phase II single-arm trial to evaluate cisplatin and gemcitabine chemotherapy in combination with sunitinib for first-line treatment of patients with advancd transitional carcinoma of the urothelium.
    Medical condition: Advanced transitional cell carcinoma of the urothelium.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10005003 Bladder cancer LLT
    9.1 10038517 Renal pelvis cancer NOS LLT
    9.1 10046375 Ureter cancer LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007593-31 Sponsor Protocol Number: prot 122 Start Date*: 2008-11-21
    Sponsor Name:FONDAZIONE RICERCA TRAPIANTO DI MIDOLLO OSSEO
    Full Title: Thiotepa dose finding study for allogeneic SCT in adult patients with high risk haematological malignancies
    Medical condition: bone marrow transplantation
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007604-15 Sponsor Protocol Number: STH14971 Start Date*: 2009-03-03
    Sponsor Name:Sheffield Teaching Hospitals NHS Foundation Trust
    Full Title: A Pilot Study of the Effect of Glucocorticoid Receptor Antagonism in Patients with Sub-Clinical Cushing's Syndrome
    Medical condition: Sub Clinical Cushing's Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011652 Cushing's syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-007623-40 Sponsor Protocol Number: D4320C00035 Start Date*: 2008-09-05
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase II, Double-blind, Placebo-Controlled, Randomised Study to Assess the Efficacy and Safety of ZD4054 in Combination with Pemetrexed (Alimta®) vs. Pemetrexed Alone in Patients with Non-small C...
    Medical condition: Locally advanced or metastatic Non small cell lung cancer (NSCLC) without predominantly squamous cell histology
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066490 Progression of non small cell lung cancer LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing) CZ (Completed) BG (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-001201-42 Sponsor Protocol Number: 4-001-LVS Start Date*: 2008-06-01
    Sponsor Name:POLICLINICO SAN DONATO IRCSS
    Full Title: Clinical trial on the use of ivabradine in patients with inappropriate sinus tachycardia
    Medical condition: Inappropriate sinus tachycardia
    Disease: Version SOC Term Classification Code Term Level
    9.1 10003133 Arrythmia sinus LLT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-001226-14 Sponsor Protocol Number: 3207-005 Start Date*: 2008-07-25
    Sponsor Name:Merck Sharp & Dohme (Sweden) AB
    Full Title: A Phase IIb, Multicenter, Randomized, Double-Blind, Placebo- Controlled, Dose-Finding Study of MK-3207 in the Treatment of Acute Migraine
    Medical condition: migraine
    Disease: Version SOC Term Classification Code Term Level
    9.1 10027599 Migraine LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed) BE (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-001236-13 Sponsor Protocol Number: 2008-001236-13 Start Date*: 2007-12-01
    Sponsor Name:AZIENDA OSPEDALIERA DI PADOVA
    Full Title: Sperimental controlled and randomized in singol blind study. Use of continuous epidural ketamina in patients submitted to toracotomy for pulmonary resection.
    Medical condition: pulmonary resection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038738 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014286-20 Sponsor Protocol Number: AGTC-AAT-002 Start Date*: 2010-12-21
    Sponsor Name:Applied Genetic Technologies Corporation
    Full Title: A Multiple-Site, Phase 2, Safety and Efficacy Trial of a Recombinant Adeno-associated Virus Vector Expressing Alpha 1 Antitrypsin (rAAV1-CB-hAAT) in Patients with Alpha 1 Antitrypsin Deficiency
    Medical condition: Alpha 1 antitrypsin deficiency.This is an inherited, genetic condition characterized by reduced serum levels of alpha-1 antitrypsin (AAT) which increases the risk of developing emphysema and liver ...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10001806 Alpha-1 anti-trypsin deficiency PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IE (Completed)
    Trial results: View results
    EudraCT Number: 2008-007507-83 Sponsor Protocol Number: CRAD001AIT12 Start Date*: 2009-03-18
    Sponsor Name:NOVARTIS FARMA
    Full Title: Once-a-day regimen or Steroid withdrawal in de novo kidney transplant recipients treated with everolimus, cyclosporin and steroids: a 12-month, prospective, randomized, multicenter, open-label stud...
    Medical condition: Recipients of a de novo kidney transplant.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10023438 Kidney transplant LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-007520-26 Sponsor Protocol Number: PROSPERA (Rasagiline) Start Date*: 2010-06-24
    Sponsor Name:Klinikum der Universität München
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to assess the Efficacy, Tolerability and Safety of Rasagiline in Subjects with Progressive Supranuclear Palsy (Phase III)
    Medical condition: Progressive Supranuclear Palsy
    Disease: Version SOC Term Classification Code Term Level
    12.0 10036813 Progressive supranuclear palsy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-011585-28 Sponsor Protocol Number: BGC20-0134-02 Start Date*: 2009-10-08
    Sponsor Name:BTG International Ltd
    Full Title: A randomised double-blind placebo-controlled phase IIa study of orally administered BGC20-0134 in patients with relapsing-remitting multiple sclerosis (RRMS)
    Medical condition: relapsing-remitting multiple sclerosis
    Disease: Version SOC Term Classification Code Term Level
    14.0 10029205 - Nervous system disorders 10063399 Relapsing-remitting multiple sclerosis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Prematurely Ended) FR (Ongoing) ES (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2009-011589-27 Sponsor Protocol Number: S337.2.001 Start Date*: 2009-09-01
    Sponsor Name:Laboratoires Fournier S.A. A Solvay Pharmaceuticals company
    Full Title: A Double-blind, Randomized, Placebo-controlled, Parallel Group Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SLV337 in Patients with Type 2 Diabetes on Metformin Mo...
    Medical condition: Type 2 diabetes mellitus (T2DM)
    Disease: Version SOC Term Classification Code Term Level
    12.0 10067585 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: PL (Completed) BG (Completed)
    Trial results: View results
    EudraCT Number: 2010-023008-29 Sponsor Protocol Number: FH-10 Start Date*: 2011-01-12
    Sponsor Name:Fundación Huésped
    Full Title: Estudio Fase 3, Aleatorizado, Abierto, Controlado de Lopinavir/Ritonavir y Lamivudina versus terapia estándar en Pacientes Infectados con HIV-1 Naïve.
    Medical condition: El propósito del estudio es comparar la seguridad y la eficacia de la combinación de Lopinavir/Ritonavir más 3TC versus terapia estándar con 2 INTIs y Lopinavir/Ritonavir en pacientes infectados co...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022416-40 Sponsor Protocol Number: 3591 Start Date*: 2011-09-30
    Sponsor Name:The Royal Marsden NHS Foundation Trust
    Full Title: A Translational, proof of the concept, study Of Pre-operative Pazopanib in treatment-naive patients with resectable soft tissue Sarcomas (TOPPS)
    Medical condition: Resectable Soft Tisue Sarcomas (cancer of conective soft tissues)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-024566-22 Sponsor Protocol Number: DMD114118 Start Date*: Information not available in EudraCT
    Sponsor Name:GlaxoSmithKline Research and Development LTD
    Full Title: A double-blind, escalating dose, randomized, placebo-controlled study to assess the pharmacokinetics, safety and tolerability of single subcutaneous injections of GSK2402968 in non-ambulant subject...
    Medical condition: Duchenne Muscular Dystrophy
    Disease: Version SOC Term Classification Code Term Level
    12.1 10013801 Duchenne muscular dystrophy LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male
    Trial protocol: FR (Ongoing) Outside EU/EEA
    Trial results: View results
    EudraCT Number: 2009-014501-13 Sponsor Protocol Number: 2008.543/44 Start Date*: 2009-11-23
    Sponsor Name:Hospices Civils de Lyon
    Full Title: Determination De La Dose Efficace De L-Bupivacaine Pour Rachianesthésie En Chirurgie Proctologique : Étude Comparative Prospective Randomisée En Double Aveugle.
    Medical condition: chirurgie ano-rectale
    Disease: Version SOC Term Classification Code Term Level
    12.0 10050622 Anorectal operation LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-014516-35 Sponsor Protocol Number: L00023 GE 303 Start Date*: 2009-12-01
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: EFFICACY AND TOLERABILITY OF CHONDROITIN SULPHATE 1000MG, TWICE DAILY IN PATIENTS WITH SYMPTOMATIC KNEE OSTEOARTHRITIS
    Medical condition: Symptomatic knee osteoarthtitis
    Disease: Version SOC Term Classification Code Term Level
    12.0 10023476 Knee osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) LT (Completed) BE (Completed) EE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2009-014527-23 Sponsor Protocol Number: MG-ECALTA1 Start Date*: 2009-10-13
    Sponsor Name:KH der Elisabethinen Linz GmbH, I. Interne Abteilung
    Full Title: Anidulafungin in patients with hematologic malignancies - An open-label, prospective study to evaluate the safety profile at prophylactic and therapeutic dosages
    Medical condition: hematologic malignancies with risk for or active invasive fungal infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-014543-36 Sponsor Protocol Number: AC4113073 Start Date*: 2009-11-17
    Sponsor Name:GlaxoSmithKline Research & Development
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, 3-Way Cross-Over Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of GSK573719 Administered Once- and Twice-Daily in Subjects with COPD
    Medical condition: Chronic Obstructive Pulmonary Disease (COPD)
    Disease: Version SOC Term Classification Code Term Level
    12.0 10010952 COPD LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-014552-30 Sponsor Protocol Number: UREP-01-2009 Start Date*: 2010-04-30
    Sponsor Name:Consorci Mar Parc de Salut de Barcelona (Parc de salut MAR)
    Full Title: Ensayo clínico exploratorio, prospectivo, aleatorizado, comparativo, para determinar la eficacia y seguridad de dos protocolos para hiperestimulación ovárica controlada en mujeres que van a ser tra...
    Medical condition: Mujeres diagnosticadas de esterilidad de origen desconocido
    Disease:
    Population Age: Adults Gender: Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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