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Clinical trials

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   44336   clinical trials with a EudraCT protocol, of which   7366   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    Search Tips: Under advanced search you can use filters for Country, Age Group, Gender, Trial Phase, Trial Status, Date Range, Rare Diseases and Orphan Designation. For these items you should use the filters and not add them to your search terms in the text field.
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    44,336 result(s) found. Displaying page 786 of 2,217.
    «« First « Previous 782  783  784  785  786  787  788  789  790  Next» Last»»
    EudraCT Number: 2008-002152-26 Sponsor Protocol Number: ISRCTN86894066 Start Date*: 2009-01-20
    Sponsor Name:The Royal Marsden Foundation Trust and The Institute of Cancer Research
    Full Title: Randomised double-blind controlled phase III trial of hyperbaric oxygen therapy in patients suffering long-term adverse effects of radiotherapy for pelvic cancer
    Medical condition: Chronic radiation-induced gastrointestinal symptoms
    Disease: Version SOC Term Classification Code Term Level
    14.1 10042613 - Surgical and medical procedures 10057480 Hyperbaric oxygen therapy PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2013-001069-18 Sponsor Protocol Number: 12/0533 Start Date*: 2013-07-11
    Sponsor Name:University College London (UCL)
    Full Title: MINeralocorticoid receptor antagonist pretreatment to MINIMISE reperfusion injury after ST-Elevation Myocardial Infarction(STEMI).
    Medical condition: Cardiovascular disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10007649 Cardiovascular disorder PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2007-000004-33 Sponsor Protocol Number: IPR/18 Start Date*: 2008-10-13
    Sponsor Name:MOLMED
    Full Title: NGR012: A phase II study of NGR-hTNF administered in combination with doxorubicin every 3 weeks in patients affected by advanced or metastatic ovarian cancer
    Medical condition: Patients affected by advanced or metastatic ovarian cancer previously treated with platinum regimens (cis or carboplatin) plus paclitaxel
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10057529 Ovarian cancer metastatic PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003162-41 Sponsor Protocol Number: ET2012000058 Start Date*: 2013-01-21
    Sponsor Name:Centre Léon Bérard
    Full Title: A randomized, multicenter, open-label, phase II study of the optimal scheme of administration of pazopanib in thyroid carcinoma
    Medical condition: Iodine refractory Differentiated Thyroid Carcinoma
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10043702 Thyroid carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed)
    Trial results: View results
    EudraCT Number: 2013-001596-21 Sponsor Protocol Number: POL7080-003 Start Date*: 2013-08-19
    Sponsor Name:Polyphor Ltd
    Full Title: A phase II, open-label, multi-center study to assess pharmacokinetics (PK), safety and efficacy of POL7080 co-administered with standard of care (SoC) treatment in patients with ventilator- associa...
    Medical condition: Ventilator- associated pneumonia due to suspected or documented Pseudomonas aeruginosa infection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended) GR (Completed)
    Trial results: (No results available)
    EudraCT Number: 2011-000144-21 Sponsor Protocol Number: UCL/10/0299 Start Date*: 2011-10-05
    Sponsor Name:University College London
    Full Title: ION– Is ablative radiOiodine Necessary for low risk differentiated thyroid cancer patients
    Medical condition: Patients with differentiated thyroid cancer who are classed as low risk
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10016935 Follicular thyroid cancer PT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10065861 Hurthle cell neoplasm of the thyroid LLT
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10033701 Papillary thyroid cancer PT
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2011-005151-13 Sponsor Protocol Number: MEM-COUGH-01 Start Date*: 2012-05-17
    Sponsor Name:University of Manchester [...]
    1. University of Manchester
    2. University Hospital of South Manchester
    Full Title: Open-label Pilot Study of Memantine in Chronic Cough Patients Attending a Specialist Clinic
    Medical condition: Idiopathic and treatment resistant Chronic Cough
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004855 10066656 Chronic cough LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-005129-57 Sponsor Protocol Number: KCT02/2012-VICTORY Start Date*: 2013-02-21
    Sponsor Name:Krka, d.d., Novo mesto
    Full Title: The Efficacy and Safety of Valsartan and Combination of Valsartan and Hydrochlorothiazide in the Treatment of Patients with mild to moderate Arterial Hypertension.
    Medical condition: Patients with mild to moderate arterial hypertension.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10047065 - Vascular disorders 10020775 Hypertension arterial LLT
    14.1 10047065 - Vascular disorders 10020772 Hypertension PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2012-003835-40 Sponsor Protocol Number: RG12-024 Start Date*: 2012-12-10
    Sponsor Name:University of Birmingham
    Full Title: A multicentre, phase II randomised controlled trial evaluating cabazitaxel versus docetaxel re-challenge for the treatment of metastatic Castrate Refractory Prostate Cancer, previously treated with...
    Medical condition: Metastatic Castrate Refractory Prostate Cancer
    Disease:
    Population Age: Adults, Elderly Gender: Male
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2012-000640-10 Sponsor Protocol Number: 2012/VCC/0009 Start Date*: 2012-12-13
    Sponsor Name:Velindre NHS Trust
    Full Title: A randomised Phase II study of two pre-operative chemoradiotherapy regimes (oxaliplatin and capecitabine followed by radiotherapy with either oxaliplatin and capecitabine or paclitaxel and carbopla...
    Medical condition: Histologically confirmed operable oesophageal cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10056104 Squamous cell carcinoma of oesophagus LLT
    14.1 100000004864 10056092 Adenocarcinoma of oesophagus LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2004-001456-36 Sponsor Protocol Number: EGF100151 Start Date*: 2004-09-06
    Sponsor Name:GLAXO SMITHKLINE
    Full Title: A phase III, randomized, open-label, multicenter study comparing GW572016 and Capecitabile (Xeloda) versus Capecitabile in women with refractory advanced or metastatic breast cancer.
    Medical condition: Solid tumor treatment
    Disease: Version SOC Term Classification Code Term Level
    15.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10006279 Breast neoplasm PT
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002762-12 Sponsor Protocol Number: MESOT-TREM-2012 Start Date*: 2012-06-29
    Sponsor Name:AZIENDA OSPEDALIERA SENESE
    Full Title: A SECOND-LINE, SINGLE ARM, PHASE II CLINICAL STUDY WITH TREMELIMUMAB, A FULLY HUMANIZED ANTI-CTLA-4 MONOCLONAL ANTIBODY, AS MONOTHERAPY IN PATIENTS WITH UNRESECTABLE MALIGNANT MESOTHELIOMA
    Medical condition: Patients affected by advanced malignant mesothelioma
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10029104 Neoplasms benign, malignant and unspecified (incl cysts and polyps) SOC
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10035603 Pleural mesothelioma PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-001881-14 Sponsor Protocol Number: GIFT/1 Start Date*: 2013-03-01
    Sponsor Name:AZIENDA UNIVERSITARIA POLICLINICO UMBERTO I DI ROMA
    Full Title: A phase II clinical trial to evaluate the safety and efficacy of interferon gamma in elevating frataxin levels in Friedreich ataxia patients
    Medical condition: Friedreich's Ataxia
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029205 - Nervous system disorders 10029205 Nervous system disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004423-20 Sponsor Protocol Number: V00498TA301 Start Date*: 2013-01-10
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: STUDY OF EFFICACY AND SAFETY OF V0498 VERSUS PLACEBO IN ACUTE SORE THROAT PAIN
    Medical condition: Acute sore throat
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10049140 Pharyngotonsillitis PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) LV (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2011-005486-21 Sponsor Protocol Number: GA1102 Start Date*: 2012-01-26
    Sponsor Name:Reckitt Benckiser Healthcare (UK) Ltd.
    Full Title: A multicentre, randomised, double-blind, two arm, parallel group, placebo controlled, pilot study to assess the effect of Gaviscon Advance as add-on therapy in GORD patients with inadequate respons...
    Medical condition: Gastro Oesophageal Reflux Disease (GORD)
    Disease: Version SOC Term Classification Code Term Level
    15.1 100000004856 10066874 Gastroesophageal reflux disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000333-40 Sponsor Protocol Number: 11-534 Start Date*: 2012-07-30
    Sponsor Name:University Medical Center Utrecht
    Full Title: Towards plannable breast surgery: diagnostic accuracy of microbubble enhanced Iodine-125 seed localization of the sentinel lymph node (MIB study)
    Medical condition: Patient with breast cancer with an indication for sentinel lymph node biopsy
    Disease:
    Population Age: Adults, Elderly Gender: Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2004-001738-17 Sponsor Protocol Number: GIMEMALAL0904 Start Date*: 2004-11-08
    Sponsor Name:G.I.M.E.M.A. GRUPPO ITALIANO MALATTIE EMATOLOGICHE DELL'ADULTO
    Full Title: Evaluation of the intensification of post-remissional therapy in the treatment of high-risks adult Acute Lymphoblastic Leukemia and monitoring of the minimal residual disease
    Medical condition: Patients with T- and B-ALL; Age >14 and <61 years
    Disease: Version SOC Term Classification Code Term Level
    14.1 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10000846 Acute lymphocytic leukaemia PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005589-37 Sponsor Protocol Number: RMRHS0095 Start Date*: 2013-03-08
    Sponsor Name:University of Warwick
    Full Title: select-d: Anticoagulation Therapy in SELECTeD Cancer Patients at Risk of Recurrence of Venous Thromboembolism
    Medical condition: Venous Thromboembolism and Cancer
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004864 10007050 Cancer LLT
    14.1 100000004866 10066899 Venous thromboembolism LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2010-022899-32 Sponsor Protocol Number: TH0918 Start Date*: 2011-01-19
    Sponsor Name:Celerion
    Full Title: An open label, randomised, single dose, 5 way cross over study to compare the rate and extent of absorption of a 8.75mg Flurbiprofen lozenge with flavour and excipient base variants of a 8.75mg Fl...
    Medical condition: Sore throat
    Disease: Version SOC Term Classification Code Term Level
    12.1 10041367 Sore throat LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2011-004795-11 Sponsor Protocol Number: 26866138-MMY-3033 Start Date*: 2013-02-20
    Sponsor Name:Janssen-Cilag International N.V.
    Full Title: A Randomized, Controlled Phase 3 Study to Evaluate Optimized Retreatment and Prolonged Therapy with Bortezomib (Velcade) in Patients with Multiple Myeloma in First or Second Relapse
    Medical condition: Multiple Myeloma
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004864 10028228 Multiple myeloma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DE (Completed) BE (Completed) IT (Completed) PT (Completed) PL (Completed) FI (Completed) NL (Completed)
    Trial results: View results
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    Note, where multi-state trials are shown in search results, selecting "Full Trial details" will download full information for each of the member states/countries involved in the trial.
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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