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Clinical trials for Paracetamol

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

  • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   44349   clinical trials with a EudraCT protocol, of which   7376   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    436 result(s) found for: Paracetamol. Displaying page 8 of 22.
    EudraCT Number: 2013-005402-65 Sponsor Protocol Number: IIBSP-ANA-2013-163 Start Date*: 2015-01-19
    Sponsor Name:Institut de Recerca HSCSP
    Full Title: Efficacy and safety of anakinra (antagonist of the interleukin-1 receptor) in the treatment of periarticular inflammation in patients refractory to NSAID and / or steroids
    Medical condition: Inflammation in periarticular structures in patients refractory to NSAIDs and / or corticosteroids.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-004885-33 Sponsor Protocol Number: 04/4 Start Date*: 2008-07-29
    Sponsor Name:Bio Minerals n.v.
    Full Title: Topical treatment of hand osteoarthritis with glucosamine cream.
    Medical condition: osteoarthritis of the hands
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Completed)
    Trial results: View results
    EudraCT Number: 2007-001559-20 Sponsor Protocol Number: 95195608 Start Date*: 2007-04-17
    Sponsor Name:Cliniques Universitaires Saint-Luc
    Full Title: Steady-state pharmacokinetics of high dose acetaminophen inpost-op children. Rational use of N-acetyl cysteine for prevention of liver toxicity related to cumulative doses.
    Medical condition: Major surgery when the use of paracetamol is required for pain release
    Disease:
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2015-005561-23 Sponsor Protocol Number: KodAmpPain_1.0 Start Date*: 2016-03-16
    Sponsor Name:Klaus Olkkola
    Full Title: Effect of CYP2D6 polymorphism on the analgesic efficacy and side-effects of codeine
    Medical condition: Postoperative pain
    Disease: Version SOC Term Classification Code Term Level
    18.1 10042613 - Surgical and medical procedures 10036236 Postoperative pain relief LLT
    18.1 10042613 - Surgical and medical procedures 10036276 Postoperative analgesia PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: FI (Completed)
    Trial results: (No results available)
    EudraCT Number: 2008-008235-28 Sponsor Protocol Number: 82772673 Start Date*: 2009-01-28
    Sponsor Name:Vesa Pakanen
    Full Title: Parasetamolin käyttö oheiskipulääkkeenä oksikodonin kanssa ohitusleikkauksen jälkeisen kivun hoidossa Paracetamol as Adjuctive Treatment for Postoperative Pain after Off-Pump Bypass Surgery
    Medical condition: Patient with chronic ischemic heart disease ongoing elective coronary artery bypass grafting. Any major organ failures like heart, kidney, liver failures are excluded.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008937 Chronic ischemic heart disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FI (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2022-003273-37 Sponsor Protocol Number: LOCAL/2022/RW-01 Start Date*: 2022-12-19
    Sponsor Name:CHU de NIMES
    Full Title: Opioid-Free analgesia in Intensive Care Unit
    Medical condition: Intensive care patient requiring sedation and analgesia for invasive mechanical ventilation
    Disease: Version SOC Term Classification Code Term Level
    21.1 10042613 - Surgical and medical procedures 10022519 Intensive care PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Trial now transitioned)
    Trial results: (No results available)
    EudraCT Number: 2019-004297-26 Sponsor Protocol Number: C19-29 Start Date*: 2020-04-17
    Sponsor Name:Institut National de la Santé et de la Recherche Médicale (INSERM)
    Full Title: Prophylactic treatment of the ductus arteriosus in preterm infants by acetaminophen
    Medical condition: Patent ductus arteriosus
    Disease:
    Population Age: Preterm newborn infants, Under 18 Gender: Male, Female
    Trial protocol: FR (Completed) EE (Completed) IE (Completed) FI (Completed) BE (Completed) PT (Completed) SE (Completed) HU (Completed) DK (Completed) GB (Not Authorised) NO (Completed) AT (Completed) GR (Completed) PL (Ongoing) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-005807-41 Sponsor Protocol Number: PRE-EMPTIVE Start Date*: 2013-04-28
    Sponsor Name:"Sapienza" University of Rome
    Full Title: RANDOMIZED CLINICAL TRIAL, PLACEBO-CONTROLLED, SPLIT-MOUTH, A DOUBLE-BLIND, FOR THE EVALUATION OF THE EFFECTIVENESS OF PRE-emptive ANALGESIA BY ADMINISTRATION OF PARACETAMOL 500MG + codeine 30mg, ...
    Medical condition: POST-OPERATIVE ACUTE PAIN (DAPO)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10017947 - Gastrointestinal disorders 10031009 Oral pain PT
    14.1 10017947 - Gastrointestinal disorders 10030973 Oral discomfort PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-000559-16 Sponsor Protocol Number: 107017 Start Date*: 2006-08-09
    Sponsor Name:GlaxoSmithKline Biologicals
    Full Title: A phase IIIb randomized, open, controlled study to assess the effect of prophylactic antipyretic treatment on the rate of febrile reactions following concomitant administration of GlaxoSmithKline ...
    Medical condition: A three-dose primary vaccination of healthy infants between 9-16 weeks (63-118 days) of age at the time of the first vaccination against Streptococcus pneumoniae.
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2011-000753-24 Sponsor Protocol Number: DC2011LiBrain001 Start Date*: 2011-10-13
    Sponsor Name:VU University Medical Center
    Full Title: Central effects of endogenous GLP-1 and the GLP-1 analog liraglutide on brain satiety and reward circuits and feeding behavior in diabetes.
    Medical condition: diabetes mellitus obesity
    Disease: Version SOC Term Classification Code Term Level
    16.1 10027433 - Metabolism and nutrition disorders 10012594 Diabetes LLT
    16.1 10027433 - Metabolism and nutrition disorders 10029883 Obesity PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-004921-33 Sponsor Protocol Number: R475-OA-1758 Start Date*: 2018-11-09
    Sponsor Name:Regeneron Pharmaceuticals, Inc.
    Full Title: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients with Pain Due to Osteoarthritis of the Hip or Knee
    Medical condition: Pain due to osteoarthritis of the hip or knee
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004859 10023476 Knee osteoarthritis LLT
    20.0 100000004859 10020108 Hips osteoarthritis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) PL (Completed)
    Trial results: View results
    EudraCT Number: 2009-011856-23 Sponsor Protocol Number: ERNPL Start Date*: 2009-09-16
    Sponsor Name:OSPEDALE POLICLINICO S. MATTEO
    Full Title: Evaluation of acute postsurgery pain management in patients who undergo inguen hernia surgery
    Medical condition: Acute post surgery pain in patients who undergo inguen hernia surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10019917 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2007-001501-13 Sponsor Protocol Number: GS PSPK2 Start Date*: 2007-07-31
    Sponsor Name:ROTTAPHARM / ROTTA RESEARCH LABORATORIUM
    Full Title: An open, randomized study to investigate the plasma and synovial fluid concentrations of glucosamine before and after repeated doses of crystalline glucosamine sulfate administered as oral soluble ...
    Medical condition: Joint disorders
    Disease: Version SOC Term Classification Code Term Level
    9.1 10048794 Gonarthrosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-001833-16 Sponsor Protocol Number: PROTOCOLLO NPDEP0106 Start Date*: 2006-07-13
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Multicentric, no-profit, open, controlled randomized clinical study to evaluate comparable tolerability and efficacy of two pharmacological treatments for persistent, non oncological pain in the el...
    Medical condition: persistent non oncological pain
    Disease: Version SOC Term Classification Code Term Level
    10033371 PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2006-006165-17 Sponsor Protocol Number: L00013 CP 301 Start Date*: 2006-12-27
    Sponsor Name:PIERRE FABRE MEDICAMENT
    Full Title: EFFICACY OF AN EARLY ADMINISTRATION OF L0013CP 10 MG/DAY VERSUS PLACEBO DURING 4 WEEKS IN THE TREATMENT OF INFECTIOUS DISEASES INDUCED ARTHRITIS PAINFUL SYMPTOMS. A MULTICENTER, RANDOMISED, DOUBLE ...
    Medical condition: CHIKUNGUNYA FEVER.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-000537-24 Sponsor Protocol Number: IIS-HEPA-TEST Start Date*: 2014-07-16
    Sponsor Name:INSTITUTO DE INVESTIGACION SANITARIA LA FE
    Full Title: Pilot clinical trial phase I / IIa to determine condition, low dose and effectiveness of liver function tests (Hepatotest)
    Medical condition: Hepatic Function.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2004-000397-31 Sponsor Protocol Number: 6106A1-500 Start Date*: 2005-05-09
    Sponsor Name:Wyeth Vaccines Research
    Full Title: A Randomized Controlled Open-Label Phase IV Multi Center Study to Assess the Effect of Antipyretic Prophylactic Treatment on the Rate of Febrile Reactions Following Concomitant Contralateral Admini...
    Medical condition: Healthy infants who shall receive their first routine vaccination.
    Disease:
    Population Age: Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2009-013156-72 Sponsor Protocol Number: FAROBE/1 Start Date*: 2009-10-06
    Sponsor Name:IMAS
    Full Title: Farmacocinética en la obesidad mórbida: estudio de la influencia de dos técnicas de cirugía bariátrica (bypass Gástrico y Sleeve Gastrectomy) en el metabolismo de fármacos.
    Medical condition: Obesidad mórbida
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-004698-86 Sponsor Protocol Number: AcuZoster Effectiveness2006 Start Date*: 2008-07-16
    Sponsor Name:Schmerzambulanz Innenstadt der LMU
    Full Title: Untersuchung der analgetischen Wirkung der AKupunktur bei Patienten mit Herpes zoster im Vergleich mit einer medikamentösen Standardtherapie- Comparison of acupuncture treatment to medical standard...
    Medical condition: Patients suffering from pain due to a herpes zoster infection
    Disease: Version SOC Term Classification Code Term Level
    8.1 10019974 Herpes zoster LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-001974-11 Sponsor Protocol Number: HEPATOTEST Start Date*: 2013-08-29
    Sponsor Name:INSTITUTO DE INVESTIGACION SANITARIA LA FE
    Full Title: PILOT TRIAL FOR THE EVALUATION OF HEPATOTEST IN PREOPERATIVE ASSESSMENT IN LIVER FUNCTION.
    Medical condition: Patients with liver metastases (mainly colorectal cancer) who will be undergoing major hepatic resection (3 or more liver segments) which have been treated with neoadjuvant chemotherapy.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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